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Application of Chinese Medicine Nursing Techniques in the Sequelae of Pelvic Inflammatory Diseases: A Review
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作者 Wei Wei Lifeng Ma 《Journal of Biosciences and Medicines》 2024年第3期182-192,共11页
Sequelae of Pelvic Inflammatory Diseases (SPID) is a common and frequent disease in gynecology, which adversely affects women’s reproductive health and quality of life due to its prolonged course. In recent years, tr... Sequelae of Pelvic Inflammatory Diseases (SPID) is a common and frequent disease in gynecology, which adversely affects women’s reproductive health and quality of life due to its prolonged course. In recent years, traditional Chinese medicine (TCM) in China has gradually shown its clinical advantages in the treatment of SPID. Therefore, the present review summarizes the etiology and pathogenesis of SPID, the evidence typology, and the clinical application effects of moxibustion, herbal retention enema, acupoint compresses, external application of traditional Chinese medicine, auricular pressure beans, tuina massage, traditional Chinese medicine gongfu, and other commonly used Chinese medicine nursing techniques, with the aim of providing references and experiences for the subsequent related studies. 展开更多
关键词 Sequelae of pelvic inflammatory diseases chronic pelvic inflammatory disease Chinese Medicine Care REVIEW
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Protective effect of sevoflurane on lung function of elderly chronic obstructive pulmonary disease patients undergoing total hip arthroplasty
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作者 Yuan Yao Man-Si Zhang +1 位作者 Yue-Bing Li Ming-Zhe Zhang 《World Journal of Clinical Cases》 SCIE 2023年第31期7619-7628,共10页
BACKGROUND Chronic obstructive pulmonary disease(COPD)is a common respiratory disorder that affects the elderly population and increases the risk of postoperative pulmonary complications(PPCs)after major surgeries.Sev... BACKGROUND Chronic obstructive pulmonary disease(COPD)is a common respiratory disorder that affects the elderly population and increases the risk of postoperative pulmonary complications(PPCs)after major surgeries.Sevoflurane is a volatile anesthetic that has been shown to have anti-inflammatory and antioxidant properties and attenuate lung injury in animal models.AIM To evaluate the protective effect of sevoflurane on the lung function of elderly COPD patients undergoing total hip arthroplasty(THA).METHODS In this randomized controlled trial,we randomly assigned 120 elderly patients with COPD,who were scheduled for THA,to receive either sevoflurane(sevoflurane group)or propofol(propofol group)as the maintenance anesthetic.The primary outcome was the incidence of PPCs within seven days after surgery.The secondary outcomes were changes in the lung function parameters,inflammatory markers,oxidative stress markers,and postoperative pain scores.RESULTS The results showed that the incidence of PPCs was significantly lower in the sevoflurane group than in the propofol group(10%vs 25%,P=0.02).Furthermore,the decline in the forced expiratory volume in 1 s,forced vital capacity,and peak expiratory flow was significantly lesser in the sevoflurane group than in the propofol group at 24 h and 48 h after surgery(P<0.05).The interleukin-6,tumor necrosis factor-alpha,malondialdehyde,and 8-hydroxy-2α-deoxyguanosine levels were significantly lower in the sevoflurane group than in the propofol group at 24 h after surgery(P<0.05).The sevoflurane group showed significantly lower postoperative pain scores than the propofol group at 6 h,12 h,and 24 h after surgery(P<0.05).CONCLUSION Sevoflurane protects the lung function of elderly COPD patients undergoing THA under general anesthesia by reducing the incidence of PPCs,attenuating inflammatory and oxidative stress responses,and alleviating postoperative pain. 展开更多
关键词 SEVofLURANE PROPofOL Lung function chronic obstructive pulmonary disease Total hip arthroplasty elderly patients inflammatory markers
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Effects of smilax bockii warb polysaccharide on inflammatory mediators, apoptosis and immune cell function in rats with chronic pelvic inflammatory disease
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作者 Jin Qi Ying-Na Cui 《Journal of Hainan Medical University》 2018年第13期1-4,共4页
Objective:To study the effects of smilax bockii warb polysaccharide on inflammatory mediators, apoptosis and immune cell function in rats with chronic pelvic inflammatory disease.Methods:Female SD rats were chosen as ... Objective:To study the effects of smilax bockii warb polysaccharide on inflammatory mediators, apoptosis and immune cell function in rats with chronic pelvic inflammatory disease.Methods:Female SD rats were chosen as experimental animals and divided into control group, pelvic inflammation group and smilax bockii warb group, pelvic inflammation group and smilax bockii warb group were made into pelvic inflammation models, and smilax bockii warb group were given intragastric administration of smilax bockii warb. The contents of inflammatory mediators and the expression of apoptosis genes in uterine muscle as well as the contents of immune cells in peripheral blood were determined 21 d after molding and intervention.Results:TLR4, NF-κB, TNF-α, ICAM-1 and IL-8 levels as well as Fas, TNFR-1, GRP78, CHOP and Caspase-3 mRNA expression in uterine muscle tissue and CD3+CD8+T cell in peripheral blood of pelvic inflammation group were higher than those of control group whereas peripheral blood CD3+CD4+T cell, red blood cell C3b receptor rosette rate and erythrocyte immune complex rosette were lower than those of control group;TLR4, NF-κB, TNF-α, ICAM-1 and IL-8 levels as well as Fas, TNFR-1, GRP78, CHOP and Caspase-3 mRNA expression in uterine muscle tissue as well as CD3+CD8+T cell in peripheral blood of smilax bockii warb group were lower than those of pelvic inflammation group whereas peripheral blood CD3+CD4+T cell, red blood cell C3b receptor rosette rate and erythrocyte immune complex rosette were higher than those of pelvic inflammation group. Conclusion:Smilax bockii warb polysaccharide for chronic pelvic inflammatory disease intervention can inhibit the inflammatory mediator secretion, apoptosis and regulate the immune cell function. 展开更多
关键词 chronic pelvic inflammatory disease Smilax bockii warb inflammatory MEDIATOR APOPTOSIS Immune FUNCTION
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Effect of Zhuang Yi Liu Fang Teng Fang on the Expression of TNF-αand NF-κB in Chronic Pelvic Inflammatory Disease(CPID)Model Rats
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作者 Gang Li Zhiyong Cao +1 位作者 Jingqin Chen Gang Fang 《Journal of Clinical and Nursing Research》 2020年第4期95-98,共4页
Objecrive:To investigate the expression of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory disease(CPID)model rats.Methods:40 female rats that adaptive fed for 5 days were randomly divided into normal gr... Objecrive:To investigate the expression of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory disease(CPID)model rats.Methods:40 female rats that adaptive fed for 5 days were randomly divided into normal group,model group,high dose group,medium dose group and low dosegroup.In addition to the normal group:the rats in each group were made chronic pelvic inflammatory model by mechanical injuuy combined with implantation of bacteria.The rats in each group were administrated by gavage for 20days.After the last administration,the level of TNF-αand NF-κB in serum was measured by ELASA method.Results:(1)after the establishment of the model,the uterus of the chronic pelvic inflammatory model rats showed the pathological damage of chroic infilammation;the levels of lNF-αand NF-κB inserum were higher than those in the normal group,the difference was statistically significant(P<0.05).(2)After the drug intervention,the uterine tissue morphology of the rats in the Zhuang Yi Liu Fang Teng Fang Group was basically restored to normal,with only a small amount of inflammatory cell infiltration and other pathological changes;compared with the rats in the model group,the TNF-αin serum of the rats in each treatment group was lower,the difference was statistically significant(P<0.05).The expression of NF-κB in serum of each treatment group was lower fthan that of the model group(P<0.05).Conclusion:Zhuang Yi Liu Teng Fang can efectively improve the endometrial histomorphology of CPID model rats,and regulate the levels of TNF-αand NF-κB in the uterus of chronic pelvic inflammatory model rats. 展开更多
关键词 Zhuang Yi Liu Fang Teng Fang chronic pelvic inflammatory disease TNF-Α NF-ΚB
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Progress in nursing methods for chronic pelvic inflammatory disease 被引量:5
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作者 Bin Wang 《国际感染病学(电子版)》 CAS 2016年第2期31-35,共5页
Chronic pelvic inflammatory disease is a highly common gynecological disease.It is often caused by the failure to completely treat acute pelvic inflammatory disease or persistent disease due to the poor physique of pa... Chronic pelvic inflammatory disease is a highly common gynecological disease.It is often caused by the failure to completely treat acute pelvic inflammatory disease or persistent disease due to the poor physique of patients.This paper provides a summary of the recent research studies on chronic pelvic inflammatory disease. 展开更多
关键词 pelvic inflammatory disease NURSING chronic diseases SUMMARY
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Treatment of Chronic Pelvic Inflammation with Acupuncture and TDP Irradiation—A Report of 23 Cases
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作者 辛昕 徐秋玉 +1 位作者 龚东方 毛树章 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2005年第1期16-17, ,共2页
With electro-acupuncture, red-hot needling and TDP irradiation, we have successfully treated 23 cases of chronic pelvic inflammation. A report follows.
关键词 Acupuncture Therapy Radiation ADULT chronic disease Combined Modality Therapy FEMALE Humans pelvic inflammatory disease
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Traditional Chinese medicine nursing protocols for leukorrheal disease( pelvic inflammatory disease)
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作者 Editorial Board of Nursing of Integrated Traditional Chinese and Western Medicine 《中西医结合护理(中英文)》 2019年第1期217-223,共7页
Leukorrheal disease is an ascending infection of the female genital tract,with high morbidity among reproductive age women. Antibiotics are usually used to treat leukorrheal disease in clinic,but they can lead to a va... Leukorrheal disease is an ascending infection of the female genital tract,with high morbidity among reproductive age women. Antibiotics are usually used to treat leukorrheal disease in clinic,but they can lead to a variety of side effects if improper use or long-time use. In recent years,traditional Chinese medicine( TCM) has shown its unique advantages in the treatment of leukorrheal disease. This article mainly explored the key points of common syndromes,TCM nursing methods and health guidance of leukorrheal disease in order to further develop the advantages of TCM,improve its efficacy and standardized its nursing behavior. 展开更多
关键词 leukorrheal disease pelvic inflammatory disease MENSTRUATION chronic PAIN traditional Chinese medicine NURSING syndrome differentiation
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Clinical Observation on Abdominal Cluster-Needling for Treatment of Chronic Annexitis
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作者 洪建云 王新中 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第3期203-204,共2页
Chronic annexitis is a frequently encountered disease at clinic. According to clinical experience in acupuncture treatment of annexitis, the author has developed an effective acupuncture method called abdominal cluste... Chronic annexitis is a frequently encountered disease at clinic. According to clinical experience in acupuncture treatment of annexitis, the author has developed an effective acupuncture method called abdominal cluster-needling, with quite good therapeutic results as reported in the following.Clinical DataThere were altogether 66 cases of chronic annexitis in this series, which were divided randomly into the treatment group and control group. The treatment group consisted of 36 cases, ranging in age from 20-40 years, and duration of illness from 0.5-9 years. The control group consisted of 30 cases, ranging in age from 21-38 years, and duration of illness from 1-8 years. 展开更多
关键词 Acupuncture Therapy Adult chronic disease Female Humans pelvic inflammatory disease
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红花如意丸对盆腔炎性疾病所致慢性盆腔痛疗效观察
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作者 贾金英 冯丽英 贾丽阳 《吉林中医药》 2024年第10期1204-1207,共4页
目的观察红花如意丸对盆腔炎性疾病所致慢性盆腔痛患者疼痛程度、炎症反应及子宫动脉血流动力学的影响。方法选择2022年9月-2023年9月郑州大学第一附属医院中医科中西医结合妇科门诊收治的104例盆腔炎性疾病所致慢性盆腔痛患者,按照随... 目的观察红花如意丸对盆腔炎性疾病所致慢性盆腔痛患者疼痛程度、炎症反应及子宫动脉血流动力学的影响。方法选择2022年9月-2023年9月郑州大学第一附属医院中医科中西医结合妇科门诊收治的104例盆腔炎性疾病所致慢性盆腔痛患者,按照随机数表法分为治疗组及对照组,各52例。治疗组在常规抗生素治疗基础上加用红花如意丸,对照组将红花如意丸替换为空白模拟剂。比较治疗4周后2组临床疗效,中医证候积分、疼痛程度、生活质量、炎症反应、血液流速及血流动力学变化情况。结果治疗4周后,治疗组总有效率(96.15%)高于对照组(75.00%),差异有统计学意义(P<0.05);2组下腹刺痛、腰骶胀痛、带下异常、经期视觉模拟评分(VAS)、非经期VAS评分,阴道分泌物白细胞酯酶阳性率、全血红细胞沉降率(ESR)、血清白介素-6(IL-6)水平、子宫动脉阻力指数(RI)水平均较治疗前降低,且治疗组优于对照组(P<0.05);2组世界卫生组织生活质量测定简表(WHOQOL-BREF)评分,子宫血流灌注指数(PI)、最大血流速度(PSV)水平较治疗前升高,且治疗组优于对照组(P<0.05)。结论红花如意丸对盆腔炎性疾病所致慢性盆腔痛患者效果较好,可改善患者中医证候积分,缓解疼痛程度,降低炎症反应,调节血液流速及血流动力学,提高生活质量。 展开更多
关键词 盆腔炎性疾病 慢性盆腔痛 红花如意丸 疼痛 炎症反应 血流动力学
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黄熙理教授自拟败酱汤系列方治疗慢性盆腔炎的临床疗效
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作者 沈燕慧 洪丽美 +1 位作者 陈智颖 黄熙理 《延边大学医学学报》 CAS 2024年第3期303-306,共4页
目的:观察黄熙理教授自拟败酱汤系列方治疗慢性盆腔炎的临床疗效。方法:选择慢性盆腔炎患者278例,按照治疗方法的不同分为治疗A组200例和对照B组78例。A组采用黄熙理教授自拟败酱汤系列方治疗,B组采用康妇炎胶囊治疗,观察比较两组的临... 目的:观察黄熙理教授自拟败酱汤系列方治疗慢性盆腔炎的临床疗效。方法:选择慢性盆腔炎患者278例,按照治疗方法的不同分为治疗A组200例和对照B组78例。A组采用黄熙理教授自拟败酱汤系列方治疗,B组采用康妇炎胶囊治疗,观察比较两组的临床疗效、下腹痛缓解时间及治疗前后主要中医证候积分。结果:A组治疗总有效率明显高于B组(P<0.05)。治疗前炎症为中度及重度的患者,下腹痛缓解时间A组明显短于B组(P<0.05)。经治疗,A组下腹痛、腰骶酸痛评分均较B组低(P<0.05)。结论:黄熙理教授自拟败酱汤系列方治疗慢性盆腔炎能有效缓解患者下腹痛、腰骶酸痛,疗效确切。 展开更多
关键词 慢性盆腔炎 败酱汤系列方 黄熙理 辨证论治
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温针灸联合中药内服治疗慢性盆腔炎的系统评价
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作者 王晓怀 苟发信 +3 位作者 赵多明 张治宽 刘淑贞 景雪 《西部中医药》 2024年第10期51-55,共5页
目的:系统评价温针灸联合中药内服对慢性盆腔炎(chronic pelvic inflammatory disease,CPID)患者的临床疗效。方法:计算机检索PubMed、EMbase、The Cochrane Library、万方数据、中国知网(CNKI)和中文期刊服务平台(VIP)等数据库,检索查... 目的:系统评价温针灸联合中药内服对慢性盆腔炎(chronic pelvic inflammatory disease,CPID)患者的临床疗效。方法:计算机检索PubMed、EMbase、The Cochrane Library、万方数据、中国知网(CNKI)和中文期刊服务平台(VIP)等数据库,检索查询关于温针灸联合中药内服治疗CPID的随机对照试验(randomized controlled trial,RCT)和半随机对照试验,检索时限均从各数据库建库至2024年5月。由2位研究人员独立进行文献筛选和数据提取,并对纳入研究进行质量评价,评估可能存在的偏倚风险,采用Rev Man 5.3软件对纳入研究的有效率和中医症状积分进行Meta分析。结果:共纳入14项研究,发表时间为2011-2023年,共计1370例患者;Meta分析结果显示:观察组有效率高于对照组(RR=1.23,95%CI:1.17~1.28,P<0.00001),观察组中医证候积分改善优于对照组(SMD=-3.03,95%CI:-4.42~-1.64,P<0.0001),差异均有统计学意义;14篇文献中,仅有1篇报道了不良反应,其余研究均未提及。结论:温针灸联合中药内服治疗慢性盆腔炎有一定优势,但本系统评价纳入的研究质量较低,样本量较小,尚需高质量的RCT进行进一步验证。 展开更多
关键词 慢性盆腔炎 针灸 中药 随机对照试验 Meta分析 系统评价
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阶段性服务理念在慢性盆腔炎临床护理中的应用价值探讨
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作者 张汉萍 纪红 游美凤 《中国卫生标准管理》 2024年第5期179-183,共5页
目的探讨阶段性服务理念在慢性盆腔炎临床护理中的应用。方法选取厦门大学附属妇女儿童医院2021年1月—2022年12月慢性盆腔炎患者88例,按照不同护理方法分为2组,各44例。对照组实施常规护理,研究组实施阶段性服务理念护理。比较2组各项... 目的探讨阶段性服务理念在慢性盆腔炎临床护理中的应用。方法选取厦门大学附属妇女儿童医院2021年1月—2022年12月慢性盆腔炎患者88例,按照不同护理方法分为2组,各44例。对照组实施常规护理,研究组实施阶段性服务理念护理。比较2组各项症状缓解时间、疾病知识认知评分、心理情绪评分、护理依从性、并发症发生率及护理满意度。结果与对照组比较,研究组月经紊乱、白带增多、腰腹疼痛缓解时间均更短(P<0.05);与护理前比较,2组护理后的疾病知识认知评分均有所增加,抑郁(self-ratingdepressionscale,SDS)、焦虑(self-ratinganxietyscale,SAS)评分均有所减少(P<0.05);与对照组比较,研究组护理后的疾病知识认知评分更高,SDS、SAS评分均更低(P<0.05);研究组护理依从性更高(P<0.05);研究组败血症、肠梗阻、腹膜炎合计并发症发生率(4.5%)低于对照组(22.7%)(P<0.05);研究组满意度(95.5%)高于对照组(75.0%)(P<0.05)。结论慢性盆腔炎患者临床护理中采用阶段性服务理念护理,患者的临床症状可得到更快缓解,不良心理情绪获得进一步缓解,对疾病的认知有所提升,并发症发生率有明显降低,护理依从性、护理满意度均显著提高,具有较为理想的应用价值。 展开更多
关键词 慢性盆腔炎 并发症 心理干预 护理满意度 阶段性服务理念 健康教育
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改良置管法在慢性盆腔炎患者中药保留灌肠中的应用研究
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作者 俞国红 杨紫燕 +1 位作者 孟伟洁 赵小换 《临床护理杂志》 2024年第3期71-73,共3页
目的探讨改良置管法在慢性盆腔炎(CPID)患者中药保留灌肠中的应用效果。方法采用便利抽样法,选取2022年3月-2023年3月我院收治的计划接受中药保留灌肠治疗的CPID患者104例,按随机数字表法分为对照组和实验组,各52例。对照组给予常规护... 目的探讨改良置管法在慢性盆腔炎(CPID)患者中药保留灌肠中的应用效果。方法采用便利抽样法,选取2022年3月-2023年3月我院收治的计划接受中药保留灌肠治疗的CPID患者104例,按随机数字表法分为对照组和实验组,各52例。对照组给予常规护理及传统中药保留灌肠法,实验组在对照组的基础上实施改良置管法。比较两组灌肠时患者的舒适度评分及灌肠液保留时间。结果实验组灌肠时舒适度评分高于对照组,灌肠液保留时间优于对照组(P<0.05)。结论改良置管法可改善CPID患者中药保留灌肠舒适度,延长灌肠液的保留时间,可应用于临床护理。 展开更多
关键词 慢性盆腔炎 灌肠
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妇炎净胶囊联合头孢曲松钠治疗慢性盆腔炎的临床效果
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作者 张艳 赵广峰 +1 位作者 孙修丽 辛怀丽 《中国医药》 2024年第9期1379-1382,共4页
目的探讨在头孢曲松钠的基础上联用妇炎净胶囊治疗慢性盆腔炎的效果。方法选取安徽医科大学附属亳州医院2020年10月至2023年9月收治的90例慢性盆腔炎患者,采用随机数字表法分为观察组(45例)和对照组(45例)。对照组给予头孢曲松钠进行治... 目的探讨在头孢曲松钠的基础上联用妇炎净胶囊治疗慢性盆腔炎的效果。方法选取安徽医科大学附属亳州医院2020年10月至2023年9月收治的90例慢性盆腔炎患者,采用随机数字表法分为观察组(45例)和对照组(45例)。对照组给予头孢曲松钠进行治疗,观察组在头孢曲松钠的基础上联合妇炎净胶囊进行治疗,2组均治疗7 d。比较2组的临床疗效、临床症状改善时间以及治疗前后血液流变学指标和血清炎症指标。结果观察组总有效率高于对照组[91.1%(41/45)比75.6%(34/45)],白带增多、下腹部坠胀感、腰骶胀痛改善时间均短于对照组(均P<0.05)。治疗后2组血浆黏度、全血高切黏度、红细胞沉降率、C反应蛋白、单核细胞趋化蛋白及白细胞介素6水平均低于治疗前,且观察组均低于对照组(均P<0.05)。治疗期间2组均未出现明显不良反应。结论在头孢曲松钠的基础上联合妇炎净胶囊治疗慢性盆腔炎可获得较好的效果,并能有效改善患者血液流变学紊乱的状态,降低患者体内的炎症,且安全性较好。 展开更多
关键词 慢性盆腔炎 头孢曲松钠 妇炎净胶囊
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论风药在盆腔炎性疾病后遗症治疗中的应用
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作者 王倩 刘霞 张兰 《中医药临床杂志》 2024年第3期400-404,共5页
盆腔炎性疾病后遗症是妇科常见的慢性疾病,其成因复杂,病程长,缠绵难愈,对女性的生殖健康与正常生活都产生了严重影响。风药能祛除风疾并兼有风木属性,具有“升、行、透、窜、动”的特性,针对盆腔炎性疾病后遗症“湿、瘀、郁、虚”的病... 盆腔炎性疾病后遗症是妇科常见的慢性疾病,其成因复杂,病程长,缠绵难愈,对女性的生殖健康与正常生活都产生了严重影响。风药能祛除风疾并兼有风木属性,具有“升、行、透、窜、动”的特性,针对盆腔炎性疾病后遗症“湿、瘀、郁、虚”的病因病机,能从“助运胜湿、活血化瘀、开散气结、补而不滞”四个方面发挥协同作用。文章从盆腔炎性疾病后遗症的病因病机出发,探讨了风药在本病治疗中的机理及应用,并附验案一则,为该病的中医治疗提供参考。 展开更多
关键词 风药 盆腔炎性疾病后遗症 慢性盆腔炎 病因病机 中医治疗
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左氧氟沙星联合丹黄祛瘀胶囊对慢性盆腔炎临床症状及炎症因子的影响研究
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作者 刘薇莉 殷尽 《实用妇科内分泌电子杂志》 2024年第5期74-76,共3页
目的探讨左氧氟沙星联合丹黄祛瘀胶囊治疗慢性盆腔炎的临床效果。方法选取本院52例慢性盆腔炎患者为研究对象,根据随机数字表法分为两组,各26例。对照组予以左氧氟沙星治疗,研究组予以左氧氟沙星联合丹黄祛瘀胶囊治疗,比较两组的治疗效... 目的探讨左氧氟沙星联合丹黄祛瘀胶囊治疗慢性盆腔炎的临床效果。方法选取本院52例慢性盆腔炎患者为研究对象,根据随机数字表法分为两组,各26例。对照组予以左氧氟沙星治疗,研究组予以左氧氟沙星联合丹黄祛瘀胶囊治疗,比较两组的治疗效果及炎症因子水平。结果研究组治疗总有效率为96.15%,高于对照组的76.92%,差异有统计学意义(P<0.05);治疗后,研究组白细胞介素-1β、白细胞介素-6、C-反应蛋白及肿瘤坏死因子-α水平低于对照组(P<0.05)。结论对慢性盆腔炎患者实施左氧氟沙星联合丹黄祛瘀胶囊治疗,能够取得更为确切的疗效,可有效抑制炎性因子水平,具有应用与推广价值。 展开更多
关键词 左氧氟沙星 丹黄祛瘀胶囊 慢性盆腔炎 临床症状 炎症因子
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整体护理在慢性盆腔炎患者护理中的应用对提升患者身心健康的价值
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作者 李芳 《实用妇科内分泌电子杂志》 2024年第8期92-94,共3页
目的探究整体护理在慢性盆腔炎患者护理中的应用效果及对提升身心健康的价值。方法选取90例慢性盆腔炎患者,根据随机数字表法分为对照组与观察组,每组45例。观察组采用整体护理,对照组采用常规护理。对比两组护理满意度、生活质量及心... 目的探究整体护理在慢性盆腔炎患者护理中的应用效果及对提升身心健康的价值。方法选取90例慢性盆腔炎患者,根据随机数字表法分为对照组与观察组,每组45例。观察组采用整体护理,对照组采用常规护理。对比两组护理满意度、生活质量及心理情绪。结果观察组护理满意度97.78%高于对照组的84.44%,差异有统计学意义(P<0.05)。观察组生活质量评分高于对照组,差异有统计学意义(P<0.05)。干预后两组慌乱、紧张、压抑、愤怒情绪评分低于干预前,且观察组明显低于对照组,差异有统计学意义(P<0.05)。结论整体护理应用于慢性盆腔炎患者中,可提升护理满意度,提高生活质量,缓解负性情绪,值得临床推广。 展开更多
关键词 慢性盆腔炎 整体护理 护理满意度 生活质量 心理情绪
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菝葜总黄酮对慢性盆腔炎大鼠的保护作用研究 被引量:1
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作者 宋路瑶 施婷婷 +3 位作者 马云 冯海兴 刘文钦 侯楚祺 《现代医药卫生》 2024年第5期727-734,740,共9页
目的探讨菝葜总黄酮对慢性盆腔炎(CPID)模型大鼠的治疗作用。方法建立CPID大鼠模型(苯酚胶浆化学烧伤法),将造模成功的SD大鼠按随机数字表法分为模型对照组、菝葜总黄酮高[32.4 g/(kg·d)]、中[16.2 g/(kg·d)]、低[8.1 g/(kg&#... 目的探讨菝葜总黄酮对慢性盆腔炎(CPID)模型大鼠的治疗作用。方法建立CPID大鼠模型(苯酚胶浆化学烧伤法),将造模成功的SD大鼠按随机数字表法分为模型对照组、菝葜总黄酮高[32.4 g/(kg·d)]、中[16.2 g/(kg·d)]、低[8.1 g/(kg·d)]剂量组,金刚藤胶囊组,地塞米松组,各10只。假手术处理大鼠按随机数字表法分为假手术组与本底对照组,各10只。另外设立空白对照组(10只)不作任何处理。给药14 d后检测各组大鼠血液流变学及血常规指标;观察大鼠左右侧子宫的形态变化,计算子宫肿胀率及肿胀抑制率,苏木精-伊红(HE)染色及Masson染色观察大鼠子宫病理改变。采用酶联免疫吸附试验(ELISA)检测大鼠子宫组织炎症因子白细胞介素1β(IL-1β)、IL-4、IL-6和IL-10的表达。结果与模型对照组及金刚藤胶囊组比较,菝葜总黄酮各剂量组均能显著降低CPID模型大鼠血液中白细胞、淋巴细胞、中性粒细胞数及各项血液流变学指标,降低大鼠子宫肿胀率,抑制大鼠子宫组织IL-1β及IL-6的表达,促进IL-4及IL-10的表达,并能显著减轻子宫充血、水肿症状,减少炎症细胞浸润,减轻腺体周围纤维结缔组织增生,改善子宫内膜增生及纤维化,差异均有统计学意义(P<0.01)。结论菝葜总黄酮能综合改善CPID模型大鼠症状,增强其血液流动性,改善局部血液循环,并同时抑制CPID模型大鼠子宫炎症反应及子宫纤维化增生。 展开更多
关键词 菝葜 黄酮 慢性盆腔炎 子宫 纤维化 大鼠
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正念减压法心理护理联合多元化健康宣教在慢性盆腔炎患者中的应用 被引量:2
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作者 王伟敏 张惠敏 《临床研究》 2024年第3期181-184,共4页
目的探讨慢性盆腔炎(CPID)患者应用正念减压法心理护理联合多元化健康宣教的效果。方法选取郑州市妇幼保健院2022年1月至2023年2月收治的CPID患者96例,以随机数字表法分成干预组(n=48,正念减压法心理护理联合多元化健康宣教)与对照组(n=... 目的探讨慢性盆腔炎(CPID)患者应用正念减压法心理护理联合多元化健康宣教的效果。方法选取郑州市妇幼保健院2022年1月至2023年2月收治的CPID患者96例,以随机数字表法分成干预组(n=48,正念减压法心理护理联合多元化健康宣教)与对照组(n=48,常规护理),比较两组症状评分、心理状态[贝克焦虑量表(BAI)、贝克抑郁量表(BDI-Ⅱ)]、疾病知识掌握程度及护理满意度。结果干预后,两组症状、BAI、BDI-Ⅱ评分均降低,但干预组评分显著低于对照组;干预后,两组疾病知识掌握程度均提高,但干预组评分显著高于对照组;干预组护理满意度(95.83%)显著高于对照组(81.25%),差异有统计学意义(P<0.05)。结论对CPID患者应用正念减压法心理护理联合多元化健康宣教,可缓解患者临床症状,改善心理状态,提高疾病知识掌握程度与护理满意度。 展开更多
关键词 慢性盆腔炎 正念减压法心理护理 多元化健康宣教
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基于GC-MS的血清代谢组学探究夏枯草茎叶酚酸抗慢性盆腔炎的作用机制
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作者 李珊 谭知浩 +4 位作者 肖志葵 熊苏慧 罗弘杉 谢菁琛 林丽美 《湖南中医药大学学报》 CAS 2024年第2期235-244,共10页
目的基于GC-MS的血清代谢组学探究夏枯草茎叶酚酸抗慢性盆腔炎的有效成分及其作用机制。方法本实验采用60只雌性大鼠,采用混合菌液加机械损伤对40只大鼠进行慢性盆腔炎造模处理,正常组10只大鼠不做处理,假手术组10只大鼠只做机械损伤。... 目的基于GC-MS的血清代谢组学探究夏枯草茎叶酚酸抗慢性盆腔炎的有效成分及其作用机制。方法本实验采用60只雌性大鼠,采用混合菌液加机械损伤对40只大鼠进行慢性盆腔炎造模处理,正常组10只大鼠不做处理,假手术组10只大鼠只做机械损伤。造模成功后,将模型大鼠分为模型组、康妇炎胶囊组、头孢克洛分散片组和夏枯草茎叶酚酸组,每组10只,连续给药21 d;取正常组、假手术组、模型组和夏枯草茎叶酚酸组、康妇炎胶囊组、头孢克洛分散片组大鼠血清进行代谢组学分析,并对筛选后的差异表达基因进行GO功能分析和KEGG通路富集分析。结果夏枯草茎叶酚酸能修复慢性盆腔炎组织病理损伤;代谢组学鉴定出47种代谢物,主要以糖类、氨基酸、有机酸、脂肪酸、多元醇等多种内源性物质为主;多因素分析表明,夏枯草可改善炎症大鼠血清代谢产物异常。主要差异代谢通路为氨基酸代谢、抗坏血酸和醛糖二酸代谢途径,主要差异代谢物为尿素、葡萄糖酸、D-葡萄糖醛酸、L-赖氨酸、甘氨酸、L-丝氨酸、L-苏氨酸、L-脯氨酸、L-苯丙氨酸等,还影响机体苯丙氨酸、酪氨酸和色氨酸生物合成,抗坏血酸和醛糖二酸代谢,苯丙氨酸代谢,花生四烯酸代谢,甘氨酸、丝氨酸和苏氨酸代谢。GO功能分析表明,对激素的反应、细胞对氮化合物的反应和磷酸化的正向调节等是主要参与的生物过程。KEGG通路富集结果显示,PI3K-Akt信号通路、甲状腺激素信号通路和内分泌抵抗等为主要富集的通路。结论夏枯草茎叶酚酸对慢性盆腔炎大鼠具有明显的治疗作用,其机制可能与作用于COBT、ADH1C、MAOB等靶点,干预PI3K-Akt信号通路、甲状腺激素信号通路和内分泌抵抗等信号通路,引起差异代谢物变化有关。 展开更多
关键词 夏枯草茎叶 酚酸 慢性盆腔炎 血清代谢组学 气相色谱-质谱法
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