With the increasing attention on circadian effects driven by light,lighting industry has inspired a revolution of photobiological lighting design.Due to diverse evaluation criteria for visual and non⁃visual systems,mo...With the increasing attention on circadian effects driven by light,lighting industry has inspired a revolution of photobiological lighting design.Due to diverse evaluation criteria for visual and non⁃visual systems,models that combine these evaluation parameters are indeed urgent.Thus,an integrated model for mesopic lighting evaluation of circadian effects was proposed.The circadian efficiency function adopted in this study was synthesized by CIE 1931 XYZ 2 deg color matching functions and standard scotopic sensitivity function.Then,the integrated model composed of International Commission on Illumination 1931 xy chromaticity coordinates,scotopic/photopic ratio,and illuminance could be obtained with synthesized circadian efficiency function.The model showed that for light sources with fixed chromaticity coordinates and fixed illuminance,enhancing the circadian effects is equivalent to increasing the scotopic/photopic ratio,which suggests a useful method for practitioners to explore the photobiologically reasonable spectrum for mesopic lighting.Light⁃emitting diodes spectra optimized by four⁃component color⁃mixing method were employed to figure out the property of the integrated model.展开更多
To date,most current reports on the development and optimization of artificial lighting sources have focused on the energy performance levels and limited color qualities of white light-emitting diodes(LEDs).However,th...To date,most current reports on the development and optimization of artificial lighting sources have focused on the energy performance levels and limited color qualities of white light-emitting diodes(LEDs).However,these properties are insufficient in terms of representing all performance levels required when adjusting white LEDs for healthy and smart lighting.Here,we introduce essential and advanced figures of merit pertaining to circadian performance as well as vision performance and color quality.We compare all possible properties of commercialized artificial lighting,daylight and four-package white LEDs which consist of long-wavelength pass dichroic filter(LPDF)-capped,phosphor-converted red,amber and green LEDs(pc-LEDs)and a blue LED.We show that these tunable four-package white LEDs produce a tunable circadian effect for melatonin suppression/secretion,a high color quality for color perception/reproduction,high efficiency for energy savings and tunable figures of merit for the smart LED lighting market.展开更多
目的探讨氟哌噻吨美利曲辛片对白大衣高血压患者白大衣效应及血压昼夜节律的影响。方法前瞻性选取120例白大衣高血压患者,进行汉密尔顿焦虑量表(HAMA)评分,HAMA总分>7分者共77例,然后将其按随机数字表法分为两组:治疗组39例,使用氟...目的探讨氟哌噻吨美利曲辛片对白大衣高血压患者白大衣效应及血压昼夜节律的影响。方法前瞻性选取120例白大衣高血压患者,进行汉密尔顿焦虑量表(HAMA)评分,HAMA总分>7分者共77例,然后将其按随机数字表法分为两组:治疗组39例,使用氟哌噻吨美利曲辛片,对照组38例,使用安慰剂。比较两组治疗前后动态血压监测各指标、诊室血压(CBP)值、白大衣效应(WCE)值、血压昼夜节律的变化。结果(1)治疗组治疗后白昼动态平均血压dSBP、dDBP略有上升(均为P<0.05),夜间动态平均血压nSBP、nDBP略有下降(均为P<0.05),24 h动态平均血压24 h SBP、24 h DBP无明显变化(均为P>0.05),对照组动态血压各指标均无明显变化(均为P>0.05),两组组间比较差异无统计学意义(均为P>0.05)。(2)治疗组治疗后CBP较治疗前有明显下降(均为P<0.01),对照组无明显变化(均为P>0.05),两组组间比较有统计学意义(均为P<0.01)。治疗组治疗后WCE值较治疗前均明显缩小(均为P<0.01),对照组无明显变化(均为P>0.05),两组组间比较差异有统计学意义(均为P<0.01)。(3)治疗组患者治疗后杓型血压昼夜节律的发生率明显升高(P=0.006),对照组无明显变化(P=1.0),两组组间比较差异有统计学意义(P=0.031)。结论氟哌噻吨美利曲辛片能明显降低伴有焦虑的白大衣高血压患者WCE值,改善血压昼夜节律,可作为此类患者的一种较好的用药选择。展开更多
基金Sponsored by the Opening Funds of State Key Laboratory of Building Safety and Built Environment and National Engineering Research Center of Building Technology(Grant No.BSBE2018-01)the Fundamental Research Funds for the Central Universities(Grant No.2018ZD34)the Autonomous Research Project of State Key Laboratory of Subtropical Building Science(Grant No.2017KB11).
文摘With the increasing attention on circadian effects driven by light,lighting industry has inspired a revolution of photobiological lighting design.Due to diverse evaluation criteria for visual and non⁃visual systems,models that combine these evaluation parameters are indeed urgent.Thus,an integrated model for mesopic lighting evaluation of circadian effects was proposed.The circadian efficiency function adopted in this study was synthesized by CIE 1931 XYZ 2 deg color matching functions and standard scotopic sensitivity function.Then,the integrated model composed of International Commission on Illumination 1931 xy chromaticity coordinates,scotopic/photopic ratio,and illuminance could be obtained with synthesized circadian efficiency function.The model showed that for light sources with fixed chromaticity coordinates and fixed illuminance,enhancing the circadian effects is equivalent to increasing the scotopic/photopic ratio,which suggests a useful method for practitioners to explore the photobiologically reasonable spectrum for mesopic lighting.Light⁃emitting diodes spectra optimized by four⁃component color⁃mixing method were employed to figure out the property of the integrated model.
基金This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIP)(No.2011-0017449).
文摘To date,most current reports on the development and optimization of artificial lighting sources have focused on the energy performance levels and limited color qualities of white light-emitting diodes(LEDs).However,these properties are insufficient in terms of representing all performance levels required when adjusting white LEDs for healthy and smart lighting.Here,we introduce essential and advanced figures of merit pertaining to circadian performance as well as vision performance and color quality.We compare all possible properties of commercialized artificial lighting,daylight and four-package white LEDs which consist of long-wavelength pass dichroic filter(LPDF)-capped,phosphor-converted red,amber and green LEDs(pc-LEDs)and a blue LED.We show that these tunable four-package white LEDs produce a tunable circadian effect for melatonin suppression/secretion,a high color quality for color perception/reproduction,high efficiency for energy savings and tunable figures of merit for the smart LED lighting market.
文摘目的探讨氟哌噻吨美利曲辛片对白大衣高血压患者白大衣效应及血压昼夜节律的影响。方法前瞻性选取120例白大衣高血压患者,进行汉密尔顿焦虑量表(HAMA)评分,HAMA总分>7分者共77例,然后将其按随机数字表法分为两组:治疗组39例,使用氟哌噻吨美利曲辛片,对照组38例,使用安慰剂。比较两组治疗前后动态血压监测各指标、诊室血压(CBP)值、白大衣效应(WCE)值、血压昼夜节律的变化。结果(1)治疗组治疗后白昼动态平均血压dSBP、dDBP略有上升(均为P<0.05),夜间动态平均血压nSBP、nDBP略有下降(均为P<0.05),24 h动态平均血压24 h SBP、24 h DBP无明显变化(均为P>0.05),对照组动态血压各指标均无明显变化(均为P>0.05),两组组间比较差异无统计学意义(均为P>0.05)。(2)治疗组治疗后CBP较治疗前有明显下降(均为P<0.01),对照组无明显变化(均为P>0.05),两组组间比较有统计学意义(均为P<0.01)。治疗组治疗后WCE值较治疗前均明显缩小(均为P<0.01),对照组无明显变化(均为P>0.05),两组组间比较差异有统计学意义(均为P<0.01)。(3)治疗组患者治疗后杓型血压昼夜节律的发生率明显升高(P=0.006),对照组无明显变化(P=1.0),两组组间比较差异有统计学意义(P=0.031)。结论氟哌噻吨美利曲辛片能明显降低伴有焦虑的白大衣高血压患者WCE值,改善血压昼夜节律,可作为此类患者的一种较好的用药选择。
