Based on nonlinear Mohr-Coulomb failure criterion, the analytical solutions of stability number and supporting force on twin shallow tunnels were derived using upper bound theorem of limit analysis. The optimized solu...Based on nonlinear Mohr-Coulomb failure criterion, the analytical solutions of stability number and supporting force on twin shallow tunnels were derived using upper bound theorem of limit analysis. The optimized solutions were obtained by the technique of sequential quadratic programming. When nonlinear coefficient equals 1 and internal friction angle equals 0, the nonlinear Mohr-Coulomb failure criterion degenerates into linear failure criterion. The calculated results of stability number in this work were compared with previous results, and the agreement verifies the effectiveness of the present method. Under the condition of nonlinear Mohr-Coulomb failure criterion, the results show that the supporting force on twin shallow tunnels obviously increases when the nonlinear coefficient, burial depth, ground load or pore water pressure coefficients increase. When the clear distance is 0.5to 1.0 times the diameter of tunnel, the supporting force of twin shallow tunnels reaches its maximum value, which means that the tunnels are the easiest to collapse. While the clear distance increases to 3.5 times the diameter of tunnel, the calculation for twin shallow tunnels can be carried out by the method for independent single shallow tunnel. Therefore, 3.5 times the diameter of tunnel serves as a critical value to determine whether twin shallow tunnels influence each other. In designing twin shallow tunnels,appropriate clear distance value must be selected according to its change rules and actual topographic conditions, meanwhile, the influences of nonlinear failure criterion of soil materials and pore water must be completely considered. During the excavation process, supporting system should be intensified at the positions of larger burial depth or ground load to avoid collapses.展开更多
Clear cell sarcoma(CCS)of soft tissue is extremely rare,accounting for approximately 1%of all soft tissue tumours.It is very difficult to diagnose CCS based on clinical manifestations.Magnetic resonance imaging(MRI)pr...Clear cell sarcoma(CCS)of soft tissue is extremely rare,accounting for approximately 1%of all soft tissue tumours.It is very difficult to diagnose CCS based on clinical manifestations.Magnetic resonance imaging(MRI)provides highresolution images of soft tissues and pathological features such as mucus,necrosis,bleeding,and fat through high and low signals on T1 weighted image(T1WI)and T2 weighted image(T2WI).On the other hand,the paramagnetism of melanin in CCS shortens the relaxation time of T1 and T2,and high signal intensity on T1WI and low signal intensity on T2WI can be found.This is different from most other soft tissue sarcomas.At present,the treatment method for CCS is surgical resection.MRI can effectively display the tumour edge,extent of surrounding oedema,and extent of fat involvement,which is highly important for guiding surgical resection and predicting postoperative recurrence.As an invasive sarcoma,CCS has a high risk of metastasis.Regardless of the pathological condition of the resected tumour,MRI or computed tomography(CT)should be performed every 1-2 years to assess recurrence at the primary site and to screen for metastasis in the lungs,liver,and bones.If necessary,PET-CT can be performed to evaluate the overall condition of the patient.展开更多
AIM: To retrospectively analyze the computed tomography (CT) and magnetic resonance imaging (MRI) appearances of primary clear cell carcinoma of the liver (PCCCL) and compare the imaging appearances of PCCCL and commo...AIM: To retrospectively analyze the computed tomography (CT) and magnetic resonance imaging (MRI) appearances of primary clear cell carcinoma of the liver (PCCCL) and compare the imaging appearances of PCCCL and common type hepatocellular carcinoma (CHCC) to determine whether any differences exist between the two groups. METHODS: Twenty cases with pathologically proven PCCCL and 127 cases with CHCC in the Second Affiliated Hospital of Sun Yat-sen University were included in this study. CT or MRI images from these patients were retrospectively analyzed. The following imaging findings were reviewed: the presence of liver cirrhosis, tumor size, the enhancement pattern on dynamic contrast scanning, the presence of pseudo capsules, tumor rupture, portal vein thrombosis and lymph node metastasis. RESULTS: Both PCCCL and CHCC were prone to occur in patients with liver cirrhosis, the association rate of liver cirrhosis was 80.0% and 78.7%, respectively (P > 0.05). The mean sizes of PCCCL and CHCC tumors were (7.28 ± 4.25) cm and (6.96 ± 3.98) cm, respectively. Small HCCs were found in 25.0% (5/20) of PCCCL and 19.7% (25/127) of CHCC cases. No significant differences in mean size and ratio of small HCCs were found between the two groups (P = 0.658 and 0.803, respectively). Compared with CHCC patients, PCCCL patients were more prone to form pseudo capsules (49.6% vs 75.0%, P = 0.034). Tumor rupture, typical HCC enhancement patterns and portal vein tumor thrombosis were detected in 15.0% (3/20), 72.2% (13/18) and 20.0% (4/20) of patients with PCCCL and 3.1% (4/127), 83.6% (97/116) and 17.3% (22/127) of patients with CHCC, respectively. There were no significant differences between the two groups (all P > 0.05). No patients with PCCCL and 2.4% (3/127) of patients with CHCC showed signs of lymph node metastasis (P > 0.05). CONCLUSION: The imaging characteristics of PCCCL are similar to those of CHCC and could be useful for differentiating these from other liver tumors (such as hemangioma and hepatic metastases). PCCCLs are more prone than CHCCs to form pseudo capsules.展开更多
A method of analyzing the stability of twin shallow tunnels was presented using both limit analysis with nonlinear failure criterion and reliability theory.In the condition of nonlinear failure criterion,the critical ...A method of analyzing the stability of twin shallow tunnels was presented using both limit analysis with nonlinear failure criterion and reliability theory.In the condition of nonlinear failure criterion,the critical clear distancesof twin shallow tunnels were obtained by analyzing the change of surrounding pressure.A reliability model was established based on limit state equation,and the failure probability was solved by virtue of Monte Carlo method.Safety factor and corresponding clear distance of different safety levels were obtained by introducing a target reliability index.The scope of clear distance for different safety levels is described,which can be used as a supplement and improvement to the design codes of tunnels.展开更多
BACKGROUND Clear cell sarcoma(CCS)is a rare and highly malignant soft tissue tumor,usually occurring in the deep soft tissues of the distal tendons and aponeurosis of the extremities,especially the feet and knees.CCS ...BACKGROUND Clear cell sarcoma(CCS)is a rare and highly malignant soft tissue tumor,usually occurring in the deep soft tissues of the distal tendons and aponeurosis of the extremities,especially the feet and knees.CCS originating in the head and neck is extremely rare.The clinical manifestations of CCS in the head and neck are not typical,and the imaging manifestations have certain characteristics,but the diagnosis still depends on pathological examination and genetic testing.CASE SUMMARY A 33-year-old male patient had paroxysmal headache for more than 4 years,accompanied by nausea and vomiting,which could be relieved after rest.Computed tomography angiography showed a left paraspinal soft tissue mass.Contrast-enhanced imaging showed obvious uneven enhancement with adjacent bone lytic destruction.Magnetic resonance imaging examination showed isosignal on T_(1)-weighted images,slightly high signal on T_(2)-weighted images(T_(2)WI),high signal on Tirm fat suppression sequence,significantly high signal on diffusion weighted imaging,and obvious and uneven enhancement.The lesion invaded the anterior medulla oblongata through the left atlantoaxial foramen and compressed the cervical spinal cord on T_(2)WI.Primary CCS of soft tissue was diagnosed by pathology and genetic examination.CONCLUSION CCS should be considered in the differential diagnosis of soft tissue tumors of the head and neck,and their diagnosis depends on pathological examination and genetic testing.展开更多
The paper considers the mechanism of the Big Bang energy influence on the creation of space-time fields of four structures of the Universe from the 1st type Ether (the Main Field and three spheres of the Relic). It ex...The paper considers the mechanism of the Big Bang energy influence on the creation of space-time fields of four structures of the Universe from the 1st type Ether (the Main Field and three spheres of the Relic). It explains how the Big Bang energy leads to the processes of “melting” in these structures, generating emergent properties that are different from their properties before the Big Bang. The key role of the Big Bang in completing the process of formation of 70% of DE is emphasized. It is shown that the Big Bang preceded the emergence of the furcation point, which chose several directions for the creation of cosmic matter—it was the combined efforts of these directions that created the visible worlds. The principle of dynamic equilibrium is considered the main criterion of the space-time field, in contrast to other physical fields, which is a necessary prerequisite for the quantization of the gravitational field. A spin particle is introduced, capable of emitting special particles—spitons, the characteristics of which are associated with the topology of the Mobius strip and determine the spinor properties of gravitational fields. The mechanism of interaction of particles of the 2nd type of Ether with the fields of space-time is described, allowing the creation of matter first and then the materiality of visible worlds. At the same time, the role of the “matter-negotiator” in the creation process of visible worlds of the Universe is especially highlighted. Since the new properties of gravitational fields go beyond Einstein’s standard theory of gravity, it is proposed to build a new theory of space-time that generalizes it and has a clear geometric interpretation. The proposed theory is based on the action built on a full set of invariants of the Ricci tensor. Within the framework of the Poincaré theory, the classification of furcation points is considered. The processes at the furcation point are described by the Gauss-Laplace curve, for which the principle of conservation of probability density is introduced when considering the transition at the furcation point to four different directions of development.展开更多
量子纠缠是执行量子计算和构建量子通信网络的关键资源,制备与操控纠缠态光场是实现量子信息处理的基础要素.本文提出了利用双端光学腔倍频产生四组份纠缠态的理论模型,从耦合波方程出发得到Ⅱ类倍频过程的传输矩阵,通过腔内自再现方程...量子纠缠是执行量子计算和构建量子通信网络的关键资源,制备与操控纠缠态光场是实现量子信息处理的基础要素.本文提出了利用双端光学腔倍频产生四组份纠缠态的理论模型,从耦合波方程出发得到Ⅱ类倍频过程的传输矩阵,通过腔内自再现方程和输入输出传输矩阵理论研究了输出的两束倍频光的噪声特性;对于两束倍频光和两束基频泵浦场,利用多组份纠缠光场的充分必要判据PPT方法(positivity under partial transposition criterion)分析了最小辛本征值与泵浦功率及分析频率之间的关系,研究结果表明基频泵浦光与倍频光之间存在四组份纠缠.展开更多
基金Project(2013CB036004)supported by the National Basic Research Program of ChinaProject(51378510)supported by the NationalNatural Science Foundation of ChinaProject(CX2013B077)supported by Hunan Provincial Innovation Foundation for Postgraduate,China
文摘Based on nonlinear Mohr-Coulomb failure criterion, the analytical solutions of stability number and supporting force on twin shallow tunnels were derived using upper bound theorem of limit analysis. The optimized solutions were obtained by the technique of sequential quadratic programming. When nonlinear coefficient equals 1 and internal friction angle equals 0, the nonlinear Mohr-Coulomb failure criterion degenerates into linear failure criterion. The calculated results of stability number in this work were compared with previous results, and the agreement verifies the effectiveness of the present method. Under the condition of nonlinear Mohr-Coulomb failure criterion, the results show that the supporting force on twin shallow tunnels obviously increases when the nonlinear coefficient, burial depth, ground load or pore water pressure coefficients increase. When the clear distance is 0.5to 1.0 times the diameter of tunnel, the supporting force of twin shallow tunnels reaches its maximum value, which means that the tunnels are the easiest to collapse. While the clear distance increases to 3.5 times the diameter of tunnel, the calculation for twin shallow tunnels can be carried out by the method for independent single shallow tunnel. Therefore, 3.5 times the diameter of tunnel serves as a critical value to determine whether twin shallow tunnels influence each other. In designing twin shallow tunnels,appropriate clear distance value must be selected according to its change rules and actual topographic conditions, meanwhile, the influences of nonlinear failure criterion of soil materials and pore water must be completely considered. During the excavation process, supporting system should be intensified at the positions of larger burial depth or ground load to avoid collapses.
基金Supported by Fundamental Research Funds for the Central Universities,No.2022CDJYGRH-004.
文摘Clear cell sarcoma(CCS)of soft tissue is extremely rare,accounting for approximately 1%of all soft tissue tumours.It is very difficult to diagnose CCS based on clinical manifestations.Magnetic resonance imaging(MRI)provides highresolution images of soft tissues and pathological features such as mucus,necrosis,bleeding,and fat through high and low signals on T1 weighted image(T1WI)and T2 weighted image(T2WI).On the other hand,the paramagnetism of melanin in CCS shortens the relaxation time of T1 and T2,and high signal intensity on T1WI and low signal intensity on T2WI can be found.This is different from most other soft tissue sarcomas.At present,the treatment method for CCS is surgical resection.MRI can effectively display the tumour edge,extent of surrounding oedema,and extent of fat involvement,which is highly important for guiding surgical resection and predicting postoperative recurrence.As an invasive sarcoma,CCS has a high risk of metastasis.Regardless of the pathological condition of the resected tumour,MRI or computed tomography(CT)should be performed every 1-2 years to assess recurrence at the primary site and to screen for metastasis in the lungs,liver,and bones.If necessary,PET-CT can be performed to evaluate the overall condition of the patient.
文摘AIM: To retrospectively analyze the computed tomography (CT) and magnetic resonance imaging (MRI) appearances of primary clear cell carcinoma of the liver (PCCCL) and compare the imaging appearances of PCCCL and common type hepatocellular carcinoma (CHCC) to determine whether any differences exist between the two groups. METHODS: Twenty cases with pathologically proven PCCCL and 127 cases with CHCC in the Second Affiliated Hospital of Sun Yat-sen University were included in this study. CT or MRI images from these patients were retrospectively analyzed. The following imaging findings were reviewed: the presence of liver cirrhosis, tumor size, the enhancement pattern on dynamic contrast scanning, the presence of pseudo capsules, tumor rupture, portal vein thrombosis and lymph node metastasis. RESULTS: Both PCCCL and CHCC were prone to occur in patients with liver cirrhosis, the association rate of liver cirrhosis was 80.0% and 78.7%, respectively (P > 0.05). The mean sizes of PCCCL and CHCC tumors were (7.28 ± 4.25) cm and (6.96 ± 3.98) cm, respectively. Small HCCs were found in 25.0% (5/20) of PCCCL and 19.7% (25/127) of CHCC cases. No significant differences in mean size and ratio of small HCCs were found between the two groups (P = 0.658 and 0.803, respectively). Compared with CHCC patients, PCCCL patients were more prone to form pseudo capsules (49.6% vs 75.0%, P = 0.034). Tumor rupture, typical HCC enhancement patterns and portal vein tumor thrombosis were detected in 15.0% (3/20), 72.2% (13/18) and 20.0% (4/20) of patients with PCCCL and 3.1% (4/127), 83.6% (97/116) and 17.3% (22/127) of patients with CHCC, respectively. There were no significant differences between the two groups (all P > 0.05). No patients with PCCCL and 2.4% (3/127) of patients with CHCC showed signs of lymph node metastasis (P > 0.05). CONCLUSION: The imaging characteristics of PCCCL are similar to those of CHCC and could be useful for differentiating these from other liver tumors (such as hemangioma and hepatic metastases). PCCCLs are more prone than CHCCs to form pseudo capsules.
基金Project(51378514)supported by the National Natural Science Foundation of China
文摘A method of analyzing the stability of twin shallow tunnels was presented using both limit analysis with nonlinear failure criterion and reliability theory.In the condition of nonlinear failure criterion,the critical clear distancesof twin shallow tunnels were obtained by analyzing the change of surrounding pressure.A reliability model was established based on limit state equation,and the failure probability was solved by virtue of Monte Carlo method.Safety factor and corresponding clear distance of different safety levels were obtained by introducing a target reliability index.The scope of clear distance for different safety levels is described,which can be used as a supplement and improvement to the design codes of tunnels.
文摘BACKGROUND Clear cell sarcoma(CCS)is a rare and highly malignant soft tissue tumor,usually occurring in the deep soft tissues of the distal tendons and aponeurosis of the extremities,especially the feet and knees.CCS originating in the head and neck is extremely rare.The clinical manifestations of CCS in the head and neck are not typical,and the imaging manifestations have certain characteristics,but the diagnosis still depends on pathological examination and genetic testing.CASE SUMMARY A 33-year-old male patient had paroxysmal headache for more than 4 years,accompanied by nausea and vomiting,which could be relieved after rest.Computed tomography angiography showed a left paraspinal soft tissue mass.Contrast-enhanced imaging showed obvious uneven enhancement with adjacent bone lytic destruction.Magnetic resonance imaging examination showed isosignal on T_(1)-weighted images,slightly high signal on T_(2)-weighted images(T_(2)WI),high signal on Tirm fat suppression sequence,significantly high signal on diffusion weighted imaging,and obvious and uneven enhancement.The lesion invaded the anterior medulla oblongata through the left atlantoaxial foramen and compressed the cervical spinal cord on T_(2)WI.Primary CCS of soft tissue was diagnosed by pathology and genetic examination.CONCLUSION CCS should be considered in the differential diagnosis of soft tissue tumors of the head and neck,and their diagnosis depends on pathological examination and genetic testing.
文摘The paper considers the mechanism of the Big Bang energy influence on the creation of space-time fields of four structures of the Universe from the 1st type Ether (the Main Field and three spheres of the Relic). It explains how the Big Bang energy leads to the processes of “melting” in these structures, generating emergent properties that are different from their properties before the Big Bang. The key role of the Big Bang in completing the process of formation of 70% of DE is emphasized. It is shown that the Big Bang preceded the emergence of the furcation point, which chose several directions for the creation of cosmic matter—it was the combined efforts of these directions that created the visible worlds. The principle of dynamic equilibrium is considered the main criterion of the space-time field, in contrast to other physical fields, which is a necessary prerequisite for the quantization of the gravitational field. A spin particle is introduced, capable of emitting special particles—spitons, the characteristics of which are associated with the topology of the Mobius strip and determine the spinor properties of gravitational fields. The mechanism of interaction of particles of the 2nd type of Ether with the fields of space-time is described, allowing the creation of matter first and then the materiality of visible worlds. At the same time, the role of the “matter-negotiator” in the creation process of visible worlds of the Universe is especially highlighted. Since the new properties of gravitational fields go beyond Einstein’s standard theory of gravity, it is proposed to build a new theory of space-time that generalizes it and has a clear geometric interpretation. The proposed theory is based on the action built on a full set of invariants of the Ricci tensor. Within the framework of the Poincaré theory, the classification of furcation points is considered. The processes at the furcation point are described by the Gauss-Laplace curve, for which the principle of conservation of probability density is introduced when considering the transition at the furcation point to four different directions of development.
文摘量子纠缠是执行量子计算和构建量子通信网络的关键资源,制备与操控纠缠态光场是实现量子信息处理的基础要素.本文提出了利用双端光学腔倍频产生四组份纠缠态的理论模型,从耦合波方程出发得到Ⅱ类倍频过程的传输矩阵,通过腔内自再现方程和输入输出传输矩阵理论研究了输出的两束倍频光的噪声特性;对于两束倍频光和两束基频泵浦场,利用多组份纠缠光场的充分必要判据PPT方法(positivity under partial transposition criterion)分析了最小辛本征值与泵浦功率及分析频率之间的关系,研究结果表明基频泵浦光与倍频光之间存在四组份纠缠.