The cleavage of DNA （pBR322） by [Cu（Dime-biim）2（H2O）]（ClO4）2 （Dime-biim=1, 1＇- dimethyl-2, 2＇-biimidazole） was investigated. The results showed that the complex could cleave DNA efficiently at pH=8.0 and 3...The cleavage of DNA （pBR322） by [Cu（Dime-biim）2（H2O）]（ClO4）2 （Dime-biim=1, 1＇- dimethyl-2, 2＇-biimidazole） was investigated. The results showed that the complex could cleave DNA efficiently at pH=8.0 and 37℃.展开更多
Copper (II) complex derived from 2, 2'-pyridil ligand has been, demonstrated to cleave efficiently DNA at micromolar concentrations at room temperature and pH 7.25.
基金The authors acknowledge the support of the National Natural Science Foundation of China No.:2017 103 1)the Shanxi Provincial Natural Science Foundation for Youth(No.:20011007).
文摘The cleavage of DNA （pBR322） by [Cu（Dime-biim）2（H2O）]（ClO4）2 （Dime-biim=1, 1＇- dimethyl-2, 2＇-biimidazole） was investigated. The results showed that the complex could cleave DNA efficiently at pH=8.0 and 37℃.
基金Young Science Foundation of Shanxi Province (No.20001005).
文摘Copper (II) complex derived from 2, 2'-pyridil ligand has been, demonstrated to cleave efficiently DNA at micromolar concentrations at room temperature and pH 7.25.
