Objective:To observe and analyze the effect of bacterial resistance monitoring in clinical microbiology testing.Methods:600 microbial specimens collected in our hospital in the past year(April 2021 to April 2022)were ...Objective:To observe and analyze the effect of bacterial resistance monitoring in clinical microbiology testing.Methods:600 microbial specimens collected in our hospital in the past year(April 2021 to April 2022)were used as the test subjects of this study.The specimens were divided into Group A(control group)and Group B(research group),with 300 cases in each group.Group A consisted of blood culture specimens,while Group B consisted of sputum specimens.After the tests were completed,the rates of unfavorable and favorable results,bacterial species distribution,and bacterial drug resistance of the specimens in both groups were compared.Results:Among group A specimens,29 cases were positive(9.67%)and 271 cases were negative(90.33%);among group B specimens,99 cases were positive(33.00%)and 201 cases were negative(66.00%);the difference between the two groups of data was statistically significant(P<0.05).As for the distribution of the types of bacteria,there were 472 cases of Gram-negative bacteria and 128 cases of Gram-positive bacteria.Conclusion:Bacterial resistance monitoring is helpful in clinical microbiology testing.Through proper monitoring,bacterial resistance can be well understood.In this way,patients get to receive appropriate treatment measures and suitable antibacterial prescriptions,thereby improving the patient outcome.展开更多
900 abusers were tested for the presence of drug abuse and coronavirus disease.In the early stage,the throat and noise samples of these patients were examined by polymerase chain reaction(PCR).The mean age of the stud...900 abusers were tested for the presence of drug abuse and coronavirus disease.In the early stage,the throat and noise samples of these patients were examined by polymerase chain reaction(PCR).The mean age of the study group is 42±23.Hematological and serological examinations were performed on 131 patients.All data were analyzed by t-test and one-way analysis of variance(ANOVA).Therefore,P<0.05 is considered as the significance of the test results.The results showed that 131 patients in the study group had positive results of PCR tests and nearby they had Covid-19.Approximately 90%of patients with coronavirus disease showed positive serological tests and lymphopenic condition.All of urine or blood samples in the 131 patients were positive for the presence of abuse drugs.C-reactive protein(CRP)is one of important serologic test that detected on these patients.This study showed the importance of molecular genetics test such as PCR and also hematology and serology tests in distinguish of coronavirus diseases.展开更多
In China,50%of Knee Osteoarthritis(KOA)patients will be treated with Traditional Chinese Medicine or a combination of Traditional Chinese and Western Medicine,which call for objective efficacy evaluation methods.The c...In China,50%of Knee Osteoarthritis(KOA)patients will be treated with Traditional Chinese Medicine or a combination of Traditional Chinese and Western Medicine,which call for objective efficacy evaluation methods.The collection,processing and fusion of multisource data were taken as the main methods,with 150 KOA patients and 100 healthy people as an example to design prospective clinical tests.Data were collected with tongue inspection APP,infrared instrument and channel instrument,etc.And the analysis,screening,fusion and modelling of multi-source data were conducted.The traditional clinical tests have been combined with the customized information platform in this study,which is convenient for clinical tests,medical follow-ups and timely feedback to statistical analysis of data.展开更多
Objective:Vestibular dysfunction is a known risk of cochlear implantation(CI).However,the utility of the physical exam to screen CI candidates for vestibular dysfunction is not well-studied.The objective of this study...Objective:Vestibular dysfunction is a known risk of cochlear implantation(CI).However,the utility of the physical exam to screen CI candidates for vestibular dysfunction is not well-studied.The objective of this study is to evaluate the preoperative role of the clinical head impulse test(cHIT)in subjects undergoing CI surgery evaluation.Study Design Setting,and Subjects:We conducted a retrospective review of 64 adult CI candidacy cases between 2017 and 2020 at a tertiary health care center.Methods:All patients underwent audiometric testing and evaluation by the senior author.Patients with an abnormal catch-up saccade contralateral to their worse hearing ear during cHIT were referred for formal vestibular testing.Outcomes included clinical and formal vestibular results,operated ear with regard to audiometric and vestibular results,and postoperative vertigo.Results:Among all CI candidates,44%(n=28)reported preoperative disequilibrium symptoms.Overall,62%(n=40)of the cHITs were normal,33%(n=21)were abnormal,and 5%(n=3)were inconclusive.There was one patient who presented with a false positive cHIT.Among the patients who endorsed disequilibrium,43%had a positive preoperative cHIT.Fourteen percent of the subjects(n=9)without disequilibrium had an abnormal cHIT.In this cohort,bilateral vestibular impairment(71%)was more common than unilateral vestibular impairment(29%).In 3%of the cases(n=2),surgical management was revisited or altered due to cHIT findings.Conclusion:There is a high prevalence of vestibular hypofunction in the CI candidate population.Self-reported assessments of vestibular function are often not congruent with cHIT results.Clinicians should consider incorporating cHITs as part of the preoperative physical exam to potentially avoid bilateral vestibular dysfunction in a minority of patients.展开更多
A traditional Chinese medicinal capsule capable of curing HIV/AIDS has been put under clinical test with the approval of the State Food and Drug Administration.
文摘Objective:To observe and analyze the effect of bacterial resistance monitoring in clinical microbiology testing.Methods:600 microbial specimens collected in our hospital in the past year(April 2021 to April 2022)were used as the test subjects of this study.The specimens were divided into Group A(control group)and Group B(research group),with 300 cases in each group.Group A consisted of blood culture specimens,while Group B consisted of sputum specimens.After the tests were completed,the rates of unfavorable and favorable results,bacterial species distribution,and bacterial drug resistance of the specimens in both groups were compared.Results:Among group A specimens,29 cases were positive(9.67%)and 271 cases were negative(90.33%);among group B specimens,99 cases were positive(33.00%)and 201 cases were negative(66.00%);the difference between the two groups of data was statistically significant(P<0.05).As for the distribution of the types of bacteria,there were 472 cases of Gram-negative bacteria and 128 cases of Gram-positive bacteria.Conclusion:Bacterial resistance monitoring is helpful in clinical microbiology testing.Through proper monitoring,bacterial resistance can be well understood.In this way,patients get to receive appropriate treatment measures and suitable antibacterial prescriptions,thereby improving the patient outcome.
文摘900 abusers were tested for the presence of drug abuse and coronavirus disease.In the early stage,the throat and noise samples of these patients were examined by polymerase chain reaction(PCR).The mean age of the study group is 42±23.Hematological and serological examinations were performed on 131 patients.All data were analyzed by t-test and one-way analysis of variance(ANOVA).Therefore,P<0.05 is considered as the significance of the test results.The results showed that 131 patients in the study group had positive results of PCR tests and nearby they had Covid-19.Approximately 90%of patients with coronavirus disease showed positive serological tests and lymphopenic condition.All of urine or blood samples in the 131 patients were positive for the presence of abuse drugs.C-reactive protein(CRP)is one of important serologic test that detected on these patients.This study showed the importance of molecular genetics test such as PCR and also hematology and serology tests in distinguish of coronavirus diseases.
基金Supported by National Natural Science Foundation of China:Research on TCM Equipment Aided Diagnosis Model Based on Multisource Information Fusion and Domain Ontology:a Case Study of Knee Osteoarthritis(No.82074334)Beijing Natural Science Foundation of China:Multi Source Four Diagnostic Information Collection and Fusion Model Based on Portable Equipment(No.7192140)+2 种基金CACMS Innovation Fund:Joint Experimental Platform for Integrated Application of TCM Diagnosis and Treatment Equipment(No.CI2021A00113)Basic Research Business Expenses of China Academy of Chinese Medical Science:Research on TCM Aided Diagnosis Model of Coronary Heart Disease Stable Angina Pectoris Based on Modern Literature(No.YZ-202015)CACMS Special Program for Training Excellent Young Talents:Research on Matching Method of TCM Theory for Instrument Measurement Signal(No.zz13-yq-110)。
文摘In China,50%of Knee Osteoarthritis(KOA)patients will be treated with Traditional Chinese Medicine or a combination of Traditional Chinese and Western Medicine,which call for objective efficacy evaluation methods.The collection,processing and fusion of multisource data were taken as the main methods,with 150 KOA patients and 100 healthy people as an example to design prospective clinical tests.Data were collected with tongue inspection APP,infrared instrument and channel instrument,etc.And the analysis,screening,fusion and modelling of multi-source data were conducted.The traditional clinical tests have been combined with the customized information platform in this study,which is convenient for clinical tests,medical follow-ups and timely feedback to statistical analysis of data.
文摘Objective:Vestibular dysfunction is a known risk of cochlear implantation(CI).However,the utility of the physical exam to screen CI candidates for vestibular dysfunction is not well-studied.The objective of this study is to evaluate the preoperative role of the clinical head impulse test(cHIT)in subjects undergoing CI surgery evaluation.Study Design Setting,and Subjects:We conducted a retrospective review of 64 adult CI candidacy cases between 2017 and 2020 at a tertiary health care center.Methods:All patients underwent audiometric testing and evaluation by the senior author.Patients with an abnormal catch-up saccade contralateral to their worse hearing ear during cHIT were referred for formal vestibular testing.Outcomes included clinical and formal vestibular results,operated ear with regard to audiometric and vestibular results,and postoperative vertigo.Results:Among all CI candidates,44%(n=28)reported preoperative disequilibrium symptoms.Overall,62%(n=40)of the cHITs were normal,33%(n=21)were abnormal,and 5%(n=3)were inconclusive.There was one patient who presented with a false positive cHIT.Among the patients who endorsed disequilibrium,43%had a positive preoperative cHIT.Fourteen percent of the subjects(n=9)without disequilibrium had an abnormal cHIT.In this cohort,bilateral vestibular impairment(71%)was more common than unilateral vestibular impairment(29%).In 3%of the cases(n=2),surgical management was revisited or altered due to cHIT findings.Conclusion:There is a high prevalence of vestibular hypofunction in the CI candidate population.Self-reported assessments of vestibular function are often not congruent with cHIT results.Clinicians should consider incorporating cHITs as part of the preoperative physical exam to potentially avoid bilateral vestibular dysfunction in a minority of patients.
文摘A traditional Chinese medicinal capsule capable of curing HIV/AIDS has been put under clinical test with the approval of the State Food and Drug Administration.