Singular Points, Closed Orbits, Stable Manifolds and Unstable Manifolds of Second Order Autonomous Birkhoff Systems

Aim To study singular points, closed orbits, stable manifolds and unstable manifolds of a second order autonomous Birkhoff system. Methods Qualitative methods of ordinary differential equation were used. Results and Conclusion The criteria for singular points, closed orbits and hyperbolic equilibrium points of a second order autonomous Birkhoff system are given. Moreover the stability of equilibria, stable manifolds and unstable manifolds are obtained.

Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological recovery.However,the mechanism of CXCR4 upregulation in induced neural stem cells remains unclear.In this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 expression.However,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial activation.In agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury mice.Notably,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head injury.In conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neural stem cells on microglial activation via upregulation of CXCR4 and Crry,thereby promoting induced neural stem cell–mediated improvement of neuronal injury,cerebral edema,and neurological disorders following closed head injury.

如何理解“closing the barn door after the horse have escaped”?

然而,由教育部考试中心组织编写、高等教育出版社出版的《全国硕士研究生入学英语考试分析(2001年版)》对这道题的分析是:“……并且打个比喻说,马逃走了,关上马棚的大门,人们却发现骑在马上的正是这些受过教育的人他们自己。”显然,这样的分析对理解原文并不能起多少作用,读后考生仍然感到云里雾里。

Recent developments on applications of sequential loop closing and diagonal dominance control schemes to industrial multivariable system

With a focus on an industrial multivariable system, two subsystems including the flow and the level outputs are analysed and controlled, which have applicability in both real and academic environments. In such a case, at first, each subsystem is distinctively represented by its model, since the outcomes point out that the chosen models have the same behavior as corresponding ones. Then, the industrial multivariable system and its presentation are achieved in line with the integration of these subsystems, since the interaction between them can not actually be ignored. To analyze the interaction presented, the Gershgorin bands need to be acquired, where the results are used to modify the system parameters to appropriate values. Subsequently, in the view of modeling results, the control concept in two different techniques including sequential loop closing control(SLCC) scheme and diagonal dominance control(DDC) schemes is proposed to implement on the system through the Profibus network, as long as the OPC(OLE for process control) server is utilized to communicate between the control schemes presented and the multivariable system. The real test scenarios are carried out and the corresponding outcomes in their present forms are acquired. In the same way, the proposed control schemes results are compared with each other, where the real consequences verify the validity of them in the field of the presented industrial multivariable system control.

Trajectory Tracking of Vertical Take-off and Landing Unmanned Aerial Vehicles Based on Disturbance Rejection Control

We investigate the trajectory tracking problem of vertical take-off and landing (VTOL) unmanned aerial vehicles (UAV), and propose a practical disturbance rejection control strategy. Firstly, the nonlinear error model is established completely by the modified Rodrigues parameters, while considering dynamics of the servo actuators. Then, a hierarchical control scheme is applied to design the translational and rotational controllers based on the time-scale property of each subsystem, respectively. And the linear extended state observer and auxiliary observer are used to deal with the uncertainties and saturation. At last, global stability of the closed-loop system is analyzed based on the singular perturbation theory. Simulation results show the effectiveness of the proposed control strategy. © 2014 Chinese Association of Automation.

Nonlinear model characterizing stress-strain relationship and permeability change of contact compression fracture at closing stage

Understanding the stress-strain relationship and permeability change for contact compression fracture at closing stage has been a hot issue for a long time.Previous investigations of this topic were mainly focused on experimental tests;however,theoretical approaches were rarely reported.Based on this,this paper focuses on the contact fracture at closing stage when rock is uniaxially loaded,and then a theoretical model is proposed.Based on the change of fracture elasticity modulus,it shows that as crack apertures are gradually reduced in the loading process,the permeability of rock sample will decrease progressively.This scenario shows that theoretical computation matches well with the experimental results.Finally,the effects of ratio of sample size to fracture aperture(n).pore pressure(P),and initial aperture(b) on stress-strain relationship and permeability change for contact compression fracture at closing stage are analyzed.

Experimental Study of the Multi-gap Multi-channel Gas Spark Closing Switch

A coaxial multi-gap multi-channel spark switch with stainless-steel-spring ring gap electrodes is designed and investigated. The switch is triggered by a pulse applied to the cylindrical electrode outside the discharging channel through a parasitic capacitance coupling. The jitter of the switch is reduced by several short-distance gas gaps in series, and its inductance is reduced by a multi-channel discharge on account of the inductance isolation between the coils of the spring ring electrode. The experimental results indicate that the switch is of low inductance (15-30 nH), low jitter (-3 ns), and stable breakdown performance

Miller Cycle with Early Intake Valve Closing in Marine Medium-Speed Diesel Engines

In this study,a one-dimensional simulation was performed to evaluate the performance of in-cylinder combustion to control NO_(x) emissions on a four-stroke,six-cylinder marine medium-speed diesel engine.Reducing the combustion temperature is an important in-cylinder measure to decrease NO_(x) emissions of marine diesel engines.The Miller cycle is an effective method used to reduce the maximum combustion temperature in a cylinder and accordingly decrease NO_(x) emissions.Therefore,the authors of this study designed seven different early intake valve closing(EIVC)Miller cycles for the original engine,and analyzed the cycle effects on combustions and emissions in high-load conditions.The results indicate that the temperature in the cylinder was significantly reduced,whereas fuel consumption was almost unchanged.When the IVC was properly advanced,the ignition delay period increased and the premixed combustion accelerated,but the in-cylinder average pressure,temperature and NO_(x) emissions in the cylinder were lower than the original engine.However,closing the intake valve too early led to high fuel consumption.In addition,the NO_(x) emissions,in-cylinder temperature,and heat release rate remarkably increased.Therefore,the optimal timing of the EIVC varied with different loads.The higher the load was,the earlier the best advance angle appeared.Therefore,the Miller cycle is an effective method for in-engine NO_(x) purification and does not entail significant cost.

Study of the Fast-Closing Switch Used for Fault Current Limiters in Power System

This paper presents a new type of fault current limiter (FCL) based on fast closing switch, which is composed of a capacitor bank and a reactor in series. The main control component is a fast closing switch connected in parallel with the capacitors, which is driven by the electromagnetic repulsion force. It can response the order within 1 ms. When fault occurs, the switch closes and the capacitors are bypassed, and the fault current is limited by the reactor. Simulation analysis and experiment show that the electromagnetic repulsion force actuator can meet the demand of fast closing switch, it is feasible to develop the FCL with low cost and high reliability.

Analysis of the Heat Transfer Efficiency of an Automobile Engine under Different Grille Opening and Closing Conditions

Computational Fluid Dynamics is used to assess the thermal(heat transfer)performances of an automobile engine considering different grille opening and closing degrees.For this purpose the entire vehicle is modelled and three fundamental aspects are examined,namely,the open area of the air intake grille,the position of the upper and lower grilles and their shape.The results show that the opening area and position of the grille have some influence also on the aerodynamic characteristics of the automobile.With an increase in the opening angle of the grille,the CD(Drag Coefficient)value of the whole vehicle becomes higher.When the air intake grille of the car is fully open or closed,the CD value is 0.35434 or 0.31777,respectively,that is,the flow resistance in the engine compartment accounts for 10.32%of the CD value for the whole automobile.

Application of Opening and Closing Morphology in Deep Learning-Based Brain Image Registration

In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training model.How-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the boundary.Thus,the dense deformation field(DDF)is gathered on the boundary and there even appears folding phenomenon.In order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF estimation.The opening information maps supervise the registration model to focus on smaller,narrow brain regions.The closing information maps supervise the registration model to pay more attention to the complex boundary region.Then,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training process.Finally,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and VoxelMorph.Experimental results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 datasets.Especially,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.

Speech by Mme. Wang Zhizhen at the Closing Ceremony of the 2013 “Understanding and Cooperation” Dialogue

Distinguished guests,Ladies and gentlemen,friends,With the joint efforts of all of you,the 2013"Understanding&Cooperation"Dialogue,held by the Chinese Association for International Understanding(CAFIU)has successfully completed all items on its agenda.It’s time to bid farewell.During the past 4 days,we came across over half China from Beijing to Jiangxi Province,feeling the hot summer days and witnessing

Fruit production and quality improvement in aonla （Emblica Officinalis Gaertn.） through canopy management

In order to maintain the health and vigour and to sustain the productivity, a pruning experiment was conducted on four year old ＂Balwant＂ cultivar of aonla grown in laterite soil, planted at a spacing of 5m×5m. To find out the best pruning method, six levels of pruning was performed i.e., （1） Light judicious pruning, （2） Detopping of primary branches at 8 feet from ground level ＋ removal of all secondary branches, （3） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 2 feet from the base of primary branches, （4） Detopping of primary branches at 8 feet from the ground level ＋ removal of all secondary branches at 1 feet from the base of primary branches, （5） Light judicious pruning ＋ Detopping of plant canopy of at 8 feet from the ground level, （6） No pruning （control）. Results of three consecutive years of investigation revealed that light judicious pruning of thin, overlapping, criss-crossed, dead, unproductive and looping branches gave highest fruit yield in all the three years and resulted 64.4 percent yield increment over control when average of three years was considered. Severe pruning of primary and secondary branches caused drastic reduction of yield for two consecutive years after pruning. Judicious pruning helped to produce better sizeable and quality fruits.

Development of Calculation Software for Automotive Side Swing Door Closing Energy

The existing research of the automotive side swing door and the closing angle via tests and simulations. In these tests, the closing energy is mainly conducted by measuring the closing energy door closing velocity and initial door closing angle are usually not taken into consideration, so the accuracy of the test data cannot be ensured, and, meanwhile, simulations require a great deal of manpower and time. Moreover, frequent tests would give rise to the increasing research and development costs. In this paper, in response to the deficiencies of these current methods, the complicated door closing process is decomposed into the closing processes of different subsystems of door, which includes weather strip seal＇, air-binding effect, door weight, hinge, check-link and latch. Mathematical models of those subsystems are established according to their working principles during the door closing process. In addition to the theoretical research, an Excel-based software using Visual Basic Application programming language is developed to realize the mathematical models, which aims to calculate the energy consumption of the subsystems. The energy consumption of different subsystems of a production vehicle door is measured to verify the accuracy of the calculation sottware developed. The proposed research provides not only the theoretical basis for the future door closing energy research, but also an interactive method and system, effectively improving the quality and efficiency of vehicle door design.

Effect of Closing Hillsides Afforestation on Population Diversity

A logaritmic series distribution model was used to evaluate the index of population diversity (α value) inQuercus mongolica forest in Zhanguangcai Mountains, Heilongjiang, Northeastern China. The α value went up from 1.07 to 4.46–6.98, after closing hillsides for 20 years. The spatial distribution of the α value was calculated among the hill slopes. The results were as follows: middle of hill>bottom of hill>top of hill.

Synthesis and Catalytic Activity of a Two-core Ruthenium Carbene Complex: a Unique Catalyst for Ring Closing Metathesis Reaction

The reaction of a ruthenium carbide complex RuCl2（C：）（PCy3）2 with [H（Et2O）x]＋[BF4]- at a molar ratio of 1：2 produced a two-core ruthenium carbene complex, {[RuCl（=CHPCy3）（PCy3）]2（μ-Cl）3}＋·[BF4]-, in the form of a yellow-green crystalline solid in a yield of 94%. This two-core ruthenium complex is a selective catalyst for ring closing metathesis of unsubstituted terminal dienes. More importantly, no isomerized byproduct was observed for N-substrates when the two-core ruthenium complex was used as the catalyst at an elevated temperature（137 °C）, indicating that the complex is a chemo-selective catalyst for ring closing metathesis reactions.

A MICROSCOPIC DAMAGE MODEL CONSIDERING THE CHANGE OF VOID SHAPE AND APPLICATION IN THE VOID CLOSING

A microscopic damage model of ellipsoidal body containing ellipsoidal void for nonlinear matrix materials is developed under a particular coordinate. The change of void shape is considered in this model. The viscous restrained equation obtained from the model is affected by stress ?ij, void volume fraction f, material strain rate exponent m as well as the void shape. Gurson's equation is modified from the numerical solution. The modified equation is suitable for the case of nonlinear matrix materials and changeable voids. Lastly, the model is used to analyze the closing process of voids.

Research on downward crack closing of clay aquiclude in shallow coal seam safety mining

The water resisting property of aquiclude is the key factor of water conservation and safety mining, and the mining induced cracks in aquiclude is major factor of water resisting property. The aquiclude is composed by loess layer and red clay layer in Yushuwan Coal Mine, and the water reaction property of clay and loess of aquiclude was tested by soil mechanics method. The permeability coefficient of the loess is 0.856 m/d and the clay is 0.434 m/d. The dilatability coefficient of the loess is 16.1% and the clay is 14.6%. Through physical solid-liquid simulation with whole stress-stain similarity, the distribution of ＂downward crack zone＂ and ＂upward crack zone＂ was found to be the major factor of aquiclude stability. The downward crack closing length is about 30% of the downward crack length. The expanding of clay and loess with water are principal factors of downward crack closing. At last, the mechanical model of downward crack closing was constructed, and the criterion of crack closing was put forward at all. This work will provides the theoretical base for aquiclude stability research and safety mining in shallow seam.

Francis Turbine and Governor Improved Models Considering Step Closing Law of Guide Vanes for Power System Stability Analysis

The Francis turbine governing system models in PSD-BPA can’t precisely reflect the actual characteristics. Endeavor was done in this paper to solve the problem. An improved model of actuating mechanism was developed, which could reflect the step closing characteristic of hydro guide vanes. The effect of the inflection point value of actuating mechanism on load rejection was analyzed based on simulation. The non-linear Francis turbine model with power versus gate position module was researched in this paper. Based on field test, comparisons of simulation results with measured data were presented. The analysis demonstrates that the improved models of Francis turbine and governor proposed in this paper are more realistic than the models of BPA, and can be applied in power system simulation analysis better.

Closing the Gap

Until late in this century,most Ameri-cans spent time with people of all generations.Now baby boomers may not have muchcontact with old people until they re relativelyold themselves.That s because we group people by age.We put our three-year-olds together in day-care centers,our 13-year-olds in schools