Road constructing in Ethiopia is increasingly in demand to meet its medium and long term development programs.Most internal roads of Oromia city/town are cobblestone and gravel.Some portions along the alignment propos...Road constructing in Ethiopia is increasingly in demand to meet its medium and long term development programs.Most internal roads of Oromia city/town are cobblestone and gravel.Some portions along the alignment proposed and existing roads traversed low resistance of the subgrade that affect the stability of the upper layers of cobblestones.Structural failure is observed on cobblestone roads,and it would be constructed with good quality or low quality of materials.Nekemte Cobblestones Projects have been started in 2014 widely which were filled in most areas today as we observed that needs to be addressed and a corresponding remedial measures must be drawn.A possible counteractive actions had been ordered for every observed destroyed to achieve the standard road situation of the study zone.An evaluation was made use observation,interviews,laboratory test and field test to govern an appropriateness of cobblestones.The lie beneath soil used for bottom layers of road structure based on standard of Ethiopian Road Authority(ERA)low volume road standards.Therefore,result from the field test and laboratory test shown,causes of cobblestone road failures of Nekemte street segment were mostly because of the construction steps/sequence,quality of materials,road construction time,absence of appropriate design,quality supervisor,absences of drainage structures,lack of highly compaction,lack of accurately fill fine aggregate and suddenly high loads vehicle applied on cobblestone road.展开更多
Background An increasing incidence of Crohn' s disease has been found in China in recent years. Our study has been focused on evaluating the diversity of the clinical manifestations of Crohn' s disease in orde...Background An increasing incidence of Crohn' s disease has been found in China in recent years. Our study has been focused on evaluating the diversity of the clinical manifestations of Crohn' s disease in order to improve early diagnostic accuracy and therapeutic efficacy.Methods Thirty patients with active Crohn's disease were enrolled and their clinical data, including diagnostic and therapeutic results, were analyzed. Endoscopy combined with histological examination of biopsy specimens provided characteristic features of the disease. Transabdominal bowel sonography (TABS) was used for detecting intestinal complications. Nutritional supportive therapy was given to 20 subjects with active cases of the disease.Results Most patients were young adults with a higher proportion of females to males (ratio: 1.14: 1). The disease affects any segment or a combination of segments along with the alimentary tract (from the mouth to the anus). In this study, the colon and small bowel were the major sites involved. Recurrent episodes of abdominal pain in the right lower quadrant and watery diarrhea were the most common symptoms. Granulomas were identifiable in nearly one-third (30.8%) of all biopsy specimens. In moderate cases of the disease, remission was achieved more quickly through the use of oral prednisone therapy than with SASP or 5-ASA. Beneficial effects on the host's nutritional status were observed. Immunosuppressives were used on an individual basis and showed variable therapeutic effects. Sixteen patients had surgery due to intestinal obstruction or failure to respond to drug therapies. Rapid improvement after surgery was reported.Conclusion Endoscopy (with biopsy) and TABS were both crucial procedures for diagnosis. SASP (or 5-ASA) and prednisone were effective as inductive therapies. Azathioprine has demonstrable benefits after induction therapy with prednisone. Surgery, as an alternative treatment, provided another effective choice in selected patients.展开更多
文摘Road constructing in Ethiopia is increasingly in demand to meet its medium and long term development programs.Most internal roads of Oromia city/town are cobblestone and gravel.Some portions along the alignment proposed and existing roads traversed low resistance of the subgrade that affect the stability of the upper layers of cobblestones.Structural failure is observed on cobblestone roads,and it would be constructed with good quality or low quality of materials.Nekemte Cobblestones Projects have been started in 2014 widely which were filled in most areas today as we observed that needs to be addressed and a corresponding remedial measures must be drawn.A possible counteractive actions had been ordered for every observed destroyed to achieve the standard road situation of the study zone.An evaluation was made use observation,interviews,laboratory test and field test to govern an appropriateness of cobblestones.The lie beneath soil used for bottom layers of road structure based on standard of Ethiopian Road Authority(ERA)low volume road standards.Therefore,result from the field test and laboratory test shown,causes of cobblestone road failures of Nekemte street segment were mostly because of the construction steps/sequence,quality of materials,road construction time,absence of appropriate design,quality supervisor,absences of drainage structures,lack of highly compaction,lack of accurately fill fine aggregate and suddenly high loads vehicle applied on cobblestone road.
文摘Background An increasing incidence of Crohn' s disease has been found in China in recent years. Our study has been focused on evaluating the diversity of the clinical manifestations of Crohn' s disease in order to improve early diagnostic accuracy and therapeutic efficacy.Methods Thirty patients with active Crohn's disease were enrolled and their clinical data, including diagnostic and therapeutic results, were analyzed. Endoscopy combined with histological examination of biopsy specimens provided characteristic features of the disease. Transabdominal bowel sonography (TABS) was used for detecting intestinal complications. Nutritional supportive therapy was given to 20 subjects with active cases of the disease.Results Most patients were young adults with a higher proportion of females to males (ratio: 1.14: 1). The disease affects any segment or a combination of segments along with the alimentary tract (from the mouth to the anus). In this study, the colon and small bowel were the major sites involved. Recurrent episodes of abdominal pain in the right lower quadrant and watery diarrhea were the most common symptoms. Granulomas were identifiable in nearly one-third (30.8%) of all biopsy specimens. In moderate cases of the disease, remission was achieved more quickly through the use of oral prednisone therapy than with SASP or 5-ASA. Beneficial effects on the host's nutritional status were observed. Immunosuppressives were used on an individual basis and showed variable therapeutic effects. Sixteen patients had surgery due to intestinal obstruction or failure to respond to drug therapies. Rapid improvement after surgery was reported.Conclusion Endoscopy (with biopsy) and TABS were both crucial procedures for diagnosis. SASP (or 5-ASA) and prednisone were effective as inductive therapies. Azathioprine has demonstrable benefits after induction therapy with prednisone. Surgery, as an alternative treatment, provided another effective choice in selected patients.
