Measurements Of Cerebral Blood Flow in Postasphyxiated Newborns by Color Doppler Imaging（CDI）

Cerebral blood flow of 10 asphyxiated term newborns was continuously measured during the first 7 days of life and compared with that of 10 normal term infants by CDI. Frequency spectrum and blood flow variables in the anterior, middle and posterior cerebral arteries were studied. The results showed evidently lower systolic amplitude in patients than that in normal subjects. End diastolic amplitude was zero in part of vessels, and values of bloed flow variables were all lower in day 1 of the life as compared with the control groups. Frequency spectrum recovered to normal patterns in 9 survived infants in day 2. but blood flow variables recovered to normal by day 7. Values of resistance index (RI) rose to 1 in some vessels of moderate hypoxic ischemic encephalopathy (HIE) infants and stayed at 1 in the severe HIE infants. It is concluded that low CBF plays a key role in brain damage of post-asphyxiated newborns and RI may be an important parameter in the evaluation prognosis.

Measurement of Liver Size and Intrahepatic Blood Flow of Red-eared Turtles by Color Doppler Ultrasound

In the study, a total of 20 red-eared turtles （ half male and half female） were selected to conduct the measurement of liver size and intrahepatic blood flow of red-eared turtles by color Doppler ultrasound. The results showed that the fight hepatic lobe could be scanned through the right carotid anterior acoustic win- dow, and the left hepatic lobe could be scanned through the left carotid anterior acoustic window, but the vision would be obstructed by the air in trachea. The liver could also be scanned through the left femoral anterior acoustic window and the fight femoral anterior acoustic window when filling of bladder was good. The correla- tion regression analysis suggested that estimated values of liver showed no linear relationship with weight, the longest back curve and the widest back curve. Through the study, the normal indicators for ultrasound examination of red-eared turtle liver were established, in order to provide a reference for examination of turtle liver.

Predicting Endometrium Receptivity with Parameters of Spiral Artery Blood Flow

In order To evaluate whether the parameters of spiral artery blood flow, as measured by transvaginal color Doppler, may be used to assess endometrium receptivity prior to embryo transfer (ET), a retrospective study of 94 infertile women who had undergone ART treatments with different outcomes (pregnant or nonpregnant) was done. Subendometrial blood flow was evaluated. The resistance index (RI), systolic/diastolic ratio (S/D) and pulsatility index (PI) were significantly lower in those who achieved pregnancy as compared with those who did not: 0.62±0.04 vs 0.68±0.04 (P<0.001), 2.66±0.33 vs 3.19±0.39 (P<0.01) and 1.15±0.17 vs 1.34±0.22 (P<0.05), respectively. Furthermore, when RI>0.72, PI>1.6, and S/D>3.6, no pregnancy occurred. These data suggest that the parameters of spiral artery blood flow could be used as a new assay in predicting endometrial receptivity before ET.

Use of color Doppler ultrasonography in the diagnosis of anomalous connection in pancreatobiliary disease

AIM: To estimate the detectability of anomalous connection in pancreatobiliary disease (ACPBD) cases, measuring gallbladder wall blood flow (GWBF).METHODS: In the retrospective study, we enrolled 42subjects with gallbladder wall thickening. GWBF velocity was determined as an average value of the peak velocity of color signals on the gallbladder wall, three times in each case. Based on the findings on endoscopic ultrasonography (EUS) or endoscopic retrograde cholangiopancreatography (ERCP), the 42 subjects were divided into 11 cases with ACPBD and 31 cases without ACPBD. In the prospective study, the subjects were 92 cases with gallbladder wall thickening. Using the cut-off level of the flow velocity obtained in the retrospective study, the usefulness of measuring GWBF velocity in diagnosing ACPBD was evaluated.RESULTS: In the retrospective study, imaging of GWBF was obtained in 40 of the 42 subjects. The mean GWBF velocity of the ACPBD cases was 29.4±3.9 cm/s(mean±SD), which was significantly different (P＜0.0001;95% CI 5.48-13.2) from that of the without ACPBD cases(20.1±5.9 cm/s). Based on this result, we prepared a receiver operating characteristic curve, and the cut-off level appropriate for diagnosing ACPBD was estimated to be 25 cm/s. In the prospective study, GWBF was detected in 86 of the 92 subjects. Based on the EUS or ERCP findings, the 92 subjects were divided into 15 cases with ACPBD and 77 cases without ACPBD. When a cut-off level of 25 cm/s was employed, ACPBD could be diagnosed with a sensitivity of 87.0% (13/15) and a specificity of87.3% (62/71).CONCLUSION: Measurement of GWBF velocity, which is less invasive and provides objective values, is very useful for diagnosing ACPBD prior to the development of malignant tumors in cases with gallbladder wall thickening.

OCULAR BLOOD FLOW EVALUATION (POBF AND GDI) IN INJURED AND HEALTHY FELLOW EYES

Purpose: To assess if injured eyes develop ocular blood flow disturbances that may contribute to development of traumatic glaucoma. Materials and Methods: 25 patients hospitalized for eye injury and elevated IOP were evaluated 24 months after the trauma. All injured and fellow eyes underwent IOP measure, visual field (HFAII, Central 30/2SITA), pulsatile ocular blood flow analysis (POBF, OBF Labs UK), CDI examination (PSV, EDV, and RI) of Ophthalmic Artery, Central Retinal Artery, Short Posterior Ciliary Arteries. Results: IOP was significantly higher in injured eyes (15.1 vs 13.0±2.7mmHg) (P= 0,01), but only 2 eyes (8.8%) were under medical treatment POBF values were significantly lower in injured eyes: 11,25 μl/s in traumatised eyes and 15,40 μl/s in fellow eyes (P = 0.002). Resistivity Index (RI) of all investigated retrobulbar vessels was very significantly higher in injured eyes than in fellow eyes (P= 0.0001). There is no significant correlation between IOP and ocular blood flow disturbances.

TRANSVAGINAL COLOR DOPPLER STUDY OF UTEROPLACENTAL CIRCULATION IN NORMAL EARLY PREGNANCY

A cross sectional transvaginal color Doppler study of the uteroplacental circulation was performed on 105 pregnant women with normal intrauterine pregnancy. Gestational age was ranged from 4 to 12 weeks. The blood flow velocity waveforms were obtained from four separate parts of the uteroplacental circulation: uterine, arcuate, radial, and spiral arteries. The resistance index (RI) and peak systolic velocity (PSV) were analyzed. The RI significantly decreased and PSV increased with advancing gestation in uterine artery and its branches (P<0 05). The RI gradully decreased from uterine artery through arcuate, radial to spiral arteries (P<0 05). At the same time, the PSV decreased from uterine artery then arcuate to radial artery, but PSV in spiral arteries were higher than that in radial artery (P<0 05). The results showed that transvaginal color Dopper ultrasonography was a simple, reliable method to assess the uteroplacental circulation in the early pregnancy; the detection of PSV was useful parameter for better understanding of physiological and pathophysiological hemodynamic changes as well as RI.

经阴道彩色多普勒超声在子宫内膜病变患者中的应用价值

目的分析经阴道彩色多普勒超声在子宫内膜病变患者中的应用价值。方法选取2021年2月至2022年4月南昌大学第四附属医院收治的88例子宫内膜病变患者作为研究对象,所有患者均接受经阴道彩色多普勒超声及病理学检查,按照病理学检查结果将患者分为息肉组与癌变组,每组44例。比较两组二维超声子宫内膜情况、病灶血流动力学情况、经阴道彩色多普勒超声血流相关参数;以病理学检查结果为金标准,分析经阴道彩色多普勒超声对子宫内膜癌变的诊断效能。结果癌变组子宫内膜厚度厚于息肉组,内膜-肌层分界清晰、病灶回声均匀占比均低于息肉组,差异有统计学意义(P<0.05);癌变组血流丰富占比高于息肉组,差异有统计学意义(P<0.05);癌变组血流阻力指数(RI)、搏动指数(PI)均低于息肉组,时间平均峰值流速(TAP)慢于息肉组,差异有统计学意义(P<0.05);经阴道彩色多普勒超声对子宫内膜癌变的诊断灵敏度为86.36%,特异度为84.09%,准确度为85.23%;诊断息肉的灵敏度为84.09%,特异度为86.36%,准确度为85.23%。结论经阴道彩色多普勒超声对子宫内膜病变的诊断准确率较高,能通过血流动力学、RI、PI、TAP及影像学表现鉴别息肉或癌变。

二维斑点追踪技术在评估冠心病患者左心室收缩与舒张功能中的应用价值

目的探讨二维斑点追踪技术在评估老年冠心病患者左心室收缩与舒张功能中的应用价值。方法对60例老年冠心病患者(研究组)和60名健康老年人(对照组),应用彩色多普勒超声诊断仪进行左心室功能检查。比较两组血压、生化指标(三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、总胆固醇、糖化血红蛋白)及常规超声参数、二维斑点超声应变参数、血流频谱测量超声参数。结果研究组受试者收缩压、舒张压及三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、总胆固醇、糖化血红蛋白水平均高于对照组(P<0.01)。两组受试者收缩末期和舒张末期的左室内径、室间隔壁厚度、左室前/后/下壁厚度比较,差异无统计学意义(P>0.05)。研究组受试者左室舒张充盈末流速峰值/左室收缩末流速峰值低于对照组(P<0.05);两组受试者左室射血分数、左室舒张充盈末流速峰值、左室收缩末流速峰值比较,差异无统计学意义(P>0.05)。研究组受试者舒张期和收缩期的左心室前壁、后壁、下壁、室间隔的纵向、径向、周向峰值绝对值均低于对照组(P<0.01)。结论二维斑点追踪技术的抗干扰能力较强,二维斑点超声应变参数能有效反映冠心病患者左室收缩、舒张情况,具有较高的应用价值。

基于彩色多普勒超声分析胎儿脐血流对FGR的诊断价值

目的:探讨彩色多普勒超声胎儿脐血流参数对FGR的诊断价值。方法:回顾性选取2019年12月~2021年12月收治的100例FGR孕妇(研究组)及100例正常孕妇(对照组),均接受超声检测。分析胎儿超声脐血流参数与FGR的关系,Logistic回归分析FGR发生的影响因素。ROC曲线分析胎儿脐血流参数对FGR的诊断价值。结果:Logistic分析显示年龄、羊水过少、低蛋白血症、RI,PI,S/D均是FGR发病的影响因素。ROC分析显示S/D、RI、PI对FGR诊断价值高。结论:FGR胎儿彩色多普勒RI,PI,S/D异常升高,具有良好诊断价值。

高频彩超结合E-flow显像对早产儿早期脑血流灌注特点的观察

目的:探讨早产儿出生早期脑组织血流灌注特点。方法:应用高频超声结合E-flow血流显像技术,对体质量≥1 500 g早产儿(早产儿A组)35例、出生体质量<1 500 g(早产儿B组)33例、足月新生儿35例进行研究,在生后72小时内检测大脑中动脉(Middle cerebral artery,MAC)、豆纹动脉(Lenticulostriate artery,LSA)、豆纹动脉终末段(The terminal artery of lenticulostriate artery,LSAt)的血流参数,包括收缩期峰值流速(Vs)、舒张末期速度(Vd)、平均血流速度(Vm)、收缩期峰值流速与舒张末期速度的比值(S/D)、阻力指数(RI)。采用t检验比较各组间的差别。结果:早产儿A组MCA的Vs、Vd、Vm测值低于足月新生儿(P<0.05),且早产儿B组MCA的Vs、Vm低于早产儿A组(P<0.05);S/D、RI三组间比较无统计学差异(P>0.05)。早产儿A组的LSA、LSAt的血流参数Vs、Vd、Vm、S/D及RI均比足月儿组明显减低(P<0.01,P<0.05),且早产儿B组除S/D外,其余测值均低于早产儿A组(P<0.01)。结论:高频超声结合E-flow显像技术对脑实质内细小血管的血流参数进行检测,可更敏感地反映早产儿早期脑实质血流灌注的基础状态,为临床判断早产儿脑损伤时血流动力学变化提供依据。

彩色多普勒超声血流参数在卵巢癌侵袭中的诊断价值

目的探讨彩色多普勒超声血流参数评估卵巢癌周围血管侵袭的价值。方法82例卵巢癌患者均行彩色多普勒超声检查,测量动脉血管血流参数。观察周围血管侵袭情况,比较侵袭与未侵袭患者的血流参数,分析血流参数诊断血管侵袭的价值。结果侵袭组的EDV、PSV高于未侵袭组,PI、RI低于未侵袭组(P<0.05)。联合检测诊断周围血管侵袭的AUC高于EDV、PSV、PI、RI单项检测(P<0.05)。结论彩色多普勒超声血流参数诊断卵巢癌周围血管侵袭的价值较高,联合检测可提高诊断效能。

彩色多普勒成像联合子宫动脉血流参数诊断子宫肌瘤效果

目的:探究彩色多普勒成像联合子宫动脉血流参数诊断子宫肌瘤效果。方法:选取2020年1月-2023年3月本院诊治的子宫肌瘤患者38例为观察组,健康体检非子宫肌瘤者65例为对照组。比较两组超声子宫动脉血流参数,观察组以病理学结果为金标准分析彩色多普勒成像联合子宫动脉血流参数诊断子宫肌瘤价值。结果:观察组超声声像子宫肌瘤具有边界清晰、组织低回声、内部结构呈实性特点,观察组子宫动脉阻力指数、子宫动脉搏动指数、子宫动脉收缩期血流速度、子宫动脉舒张期血流速度均高于对照组(均P<0.05)。声像特征联合子宫动脉血流参数诊断子宫肌瘤的曲线下面积为0.932,灵敏度86.8%、特异度93.8%、准确率90.3%等均高于单独指标诊断。结论:彩色多普勒成像联合子宫动脉血流参数诊断子宫肌瘤具有较高的灵敏度和特异度,提高了诊断子宫肌瘤效能。

各期内痔动脉血供特性的临床研究

目的研究各期内痔动脉血供特点。方法采用经会阴多普勒超声分别对80例不同分度内痔患者(观察组)和20例志愿者(对照组)的痔供血动脉的血流量、管径大小进行检测。结果通过经会阴彩色多普勒超声手段,80例Goligher分度Ⅰ~Ⅳ度痔疮患者与20名健康志愿者进行比较。观察组痔疮动脉供血分支的平均管径为1.90±0.85 mm;明显大于对照组0.97±0.24 mm,差异有统计学意义(P<0.001)。观察组痔疮供血动脉血流47.3±28.3 cm/s明显高于对照组15.6±5.0 cm/s,两组间差异具有统计学意义(P<0.01)。结论痔疮供血动脉管径和血流与内痔病情程度呈正相关。经会阴彩色多普勒超声有望成为内痔患者合理选择治疗方式的一种检测手段。

阴道彩色多普勒超声血流显像对子宫肌瘤检查的图像特征及诊断效能分析

目的:探讨阴道彩色多普勒超声血流显像(CDFI)对子宫肌瘤的诊断效能及其图像特征.方法:选取 2020年1 月至 2022 年 12 月本院收治的 53 例子宫肌瘤患者为研究对象,纳入观察组.选取同期本院收治的 51 例子宫肉瘤患者作为对照,纳入对照组.比较两组经阴道CDFI检查的图像特征、瘤体内部血流信号,CDFI检查对两组患者的诊断效能.结果:观察组CDFI图像呈低回声、瘤体边界清楚、肌瘤内部实性患者,瘤体内部无血流信号、少量血流信号患者占比均大于对照组;瘤体边界欠清楚、肌瘤内部囊性患者、瘤体内部血流信号丰富患者占比,均小于对照组,差异均有统计学意义(P<0.05).阴道CDFI检查诊断子宫肌瘤和子宫肉瘤的特异度、灵敏度、准确率、阳性预测值、阴性预测值分别为 98.03%、96.22%、97.11%、98.07%、96.15%.结论:采取阴道CDFI检查对子宫肌瘤诊断具有较高诊断效能,可清楚显示子宫肌瘤患者图像特征.

经阴道多普勒超声血流参数评估子宫内膜癌预后的价值

目的探讨经阴道彩色多普勒超声(TVCDS)血流参数在子宫内膜癌预后评估中的应用价值。方法选取2015年1月—2019年1月我院收治的85例子宫内膜癌患者,所有纳入患者均经手术治疗并完成为期3年随访,随访日期截止至2022年1月31日,观察患者预后情况(复发与未复发,存活与病死),对比不同预后患者TVCDS血流参数[阻力指数(RI)、最高峰流速(Vmax)、搏动指数(PI)],分析上述参数评估预后的价值。结果存活63例,病死22例,复发25例,未复发60例;与未复发组相比,复发组患者RI、PI较低,Vmax较高(P<0.05),两组年龄、手术病理分期、病理分级、分化程度、LH、E2、PRL、FSH表达对比差异无显著性(P>0.05);与存活组相比,病死组患者RI、PI较低,Vmax较高(P<0.05),两组年龄、手术病理分期、病理分级、分化程度、LH、E2、PRL、FSH表达对比差异无显著性(P>0.05);绘制ROC曲线得到RI、PI、Vmax单独与联合预测复发的AUC分别为0.939、0.879、0.938、0.942,预测病死的AUC分别为0.927、0.854、0.978、0.984。结论TVCDS血流参数评估子宫内膜癌预后价值显著,可作为指导临床治疗的新靶点。

彩色多普勒超声在双波长激光治疗婴幼儿血管瘤中的应用

目的:分析彩色多普勒超声在双波长激光治疗婴幼儿血管瘤的应用价值。方法:回顾性分析2021年3月至2023年3月收治的血管瘤患者临床资料,所有患者在行Cynergy双波长激光治疗前均接受彩色多普勒超声检查,根据不同的血流信号和皮损深度,观察治疗效果及并发症发生情况。结果:198例血管瘤患儿纳入分析,共计212处皮损,其中根据血流信号分为无血流信号73例(34.3%)、稀少血流信号76例(35.8%)、中等血流信号63例(29.9%),有效率为100%,96.1%,85.7%,三组比较差异有统计学意义(P<0.05);根据皮损深度分为<1.2 mm 69例(32.5%),1.2~3.0 mm 88例(41.5%),>3 mm 55例(26.0%),有效率为100%,94.3%,83.6%,三组比较差异有统计学意义(P<0.05);在所有纳入的患者中,有21.7%的患儿出现不良反应。结论:彩色多普勒超声在双波长激光治疗婴幼儿血管瘤中具有重要的应用价值,可以实时监测治疗过程,并帮助临床医师预估疗效。

彩超评测血液透析患者自体动静脉内瘘瘘口及血流速度的价值

目的研究彩超评测血液透析(HD)患者自体动静脉内瘘(AVF)瘘口及血流速度的价值。方法选取2019年2月至2022年2月铜川市人民医院收治的150例HD患者进行前瞻性研究,其中男性87例,女性63例,年龄41~69(56.82±7.12)岁。对所有受试者均开展CT血管成像检查以及彩超检查,根据CT血管成像检查结果将患者分为狭窄组(内瘘狭窄)59例以及无狭窄组(内瘘正常)91例。比较两组肱动脉近分叉处(Qb)、瘘口近端桡动脉(Qr)、瘘口处(Qf)以及瘘口近端头静脉(Qc)的血流量。以受试者操作特征曲线(ROC)分析明确各项彩超参数评估HD患者AVF狭窄的效能,对比两组内瘘并发症发生情况。统计学方法采用t检验、χ^(2)检验。结果狭窄组Qb、Qr、Qf及Qc水平均低于无狭窄组[(377.45±103.46)ml/min比(491.52±136.71)ml/min、(320.58±102.99)ml/min比(410.89±138.46)ml/min、(476.12±112.57)ml/min比(566.43±129.85)ml/min、(519.04±120.87)ml/min比(667.36±134.53)ml/min],差异均有统计学意义(t=5.47、4.30、4.38、6.86,均P<0.05)。经ROC分析发现,Qb评估血液透析患者AVF狭窄的曲线下面积为0.854,灵敏度、特异度分别为86.92%、84.10%,均高于Qr、Qf、Qc。狭窄组静脉侧狭窄、血栓形成、静脉瘤样扩张发生率均高于无狭窄组[23.73%(14/59)比6.59%(6/91)、20.34%(12/59)比4.40%(4/91)、37.29%(22/59)比17.58%(16/91)],差异均有统计学意义(χ^(2)=9.10、9.55、7.35,均P<0.05)。结论彩超可有效评估HD患者AVF瘘口及血流速度,其中Qb在诊断HD患者AVF狭窄中的效能较佳,值得推广普及。

彩色多普勒超声检查在评价妊娠期高血压患者胎儿宫内情况中的临床意义及血流指标探析

目的:探讨彩色多普勒超声检查在评价妊娠期高血压(HDP)患者胎儿宫内情况及血流指标的价值。方法:回顾性收集2022年1月—2023年1月费县人民医院收治的106例HDP患者为观察组,并收集同期正常妊娠孕妇106例为对照组。均为单胎妊娠,且均接受彩色多普勒超声检查,对两组胎儿的脐动脉、大脑中动脉搏动指数(PI)、收缩-舒张流速比值(S/D)及阻力指数(RI)与静脉导管S峰、A峰、D峰、PI、RI值及右室Tei指数进行测定并比较。结果:观察组大脑中动脉RI、S/D及PI均比对照组低,脐动脉RI、S/D及PI均比对照组高(P<0.05):观察组胎儿的静脉导管S峰、D峰、PI、RI及右室Tei指数均比对照组高,静脉导管A峰比对照组低(P<0.05)。结论:HDP患者采用彩色多普勒超声参数可有效评估胎儿宫内情况,具有重要的临床应用价值。

经阴道彩色多普勒血流成像检查在先兆流产中的诊断效能及相关参数分析

目的:探讨经阴道彩色多普勒血流成像(CDFI)检查在先兆流产中的诊断效能及其相关参数。方法:选取2020年8月—2023年8月淄博市周村区妇幼保健院收治的先兆流产患者45例为观察组,另选同期健康妊娠孕妇45例为对照组,均行经阴道CDFI检查,比较两组黄体、子宫动脉及螺旋动脉血流,并绘制受试者工作特征(ROC)曲线分析各指标及联合检查诊断先兆流产的临床价值;比较保胎成功与保胎失败患者黄体、子宫动脉及螺旋动脉血流搏动指数(PI)、阻力指数(RI)差异。结果:观察组黄体、子宫螺旋动脉PI、RI高于对照组,差异有统计学意义(P<0.05);绘制ROC曲线显示,黄体、子宫螺旋动脉PI、RI及联合检测诊断先兆流产的AUC值分别为0.762、0.856、0.833、0.847、0.980,联合诊断价值最高;45例先兆流产患者中,保胎成功32例,保胎失败13例;保胎成功患者黄体、子宫螺旋动脉PI、RI低于保胎失败患者,差异有统计学意义(P<0.05)。结论:经阴道CDFI检查在先兆流产诊断中价值高,可明确黄体、子宫螺旋动脉血流变化,提高诊断准确性,便于早期开展保胎治疗,降低流产风险。

彩色多普勒超声对甲亢患者甲状腺血流分级的评估价值及与甲状腺激素的相关性

目的 探讨彩色多普勒超声对甲亢患者甲状腺血流分级的评估价值及与甲状腺激素的相关性。方法 本研究共收治了110例甲亢患者,选取时间为2021年1月至2022年4月,病例来源为安阳市第三人民医院,进行回顾性分析,做131I治疗前采用彩色多普勒超声对患者进行诊断,并对患者的甲状腺激素指标进行检测。采用纵横断面的彩色多普勒超声显像评定甲状腺的血流分级情况,将其分为1级和2级,分析甲状腺影像学检查血流分级与各项血清甲状腺激素相关指标之间的关系。结果 甲状腺血流分级为1级、2级患者的游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺素受体抗体(TRAb)指标之间比较,差异均有统计学意义(均P<0.05),且上述指标与甲状腺血流分级之间均呈正相关(r值=0.42、0.41、0.24,P=0.001、0.003、0.029),甲状腺血流分级越高,则FT3、FT4、TRAb指标水平越高(P=0.001、0.002、0.027)。结论 甲亢患者甲状腺血流分级为1级、2级患者的FT3、FT4、TRAb指标之间差异均有统计学意义,且上述指标与甲状腺血流分级之间均呈正相关,即彩色多普勒超声血流分级和甲状腺激素之间存在联系,在临床诊断和治疗甲亢时可将其作为一种评估手段。