Although the animal models of hepatic fibrosis developed by former researchers have pathological changes of hepatic fibrosis, they do not include charac- teristics of important TCM syndromes such as stagnation of qi, ...Although the animal models of hepatic fibrosis developed by former researchers have pathological changes of hepatic fibrosis, they do not include charac- teristics of important TCM syndromes such as stagnation of qi, deficiency of qi, liver depression, phlegm-dampness and blood stasis because of single-factor model- ing. Animal models of hepatic fibrosis and animal models integrated disease and syndrome were reviewed, and several new types of integrated disease and syndrome animal models constructed by multiple-factor modeling method were evaluated, under the guidance of etiological theory of TCM. This kind of hepatic fibrosis model animals has dual characteristics of disease and syndrome. It is consistent with pathological characteristics of hepatic fibrosis in western medicine when replicating the basic characteristics accorded with TCM syndrome. Thus, the pathogenesis and pathogenic process of clinical disease and syndrome formation is simulated more ac- curately, providing a new platform and pathway for studying hepatic fibrosis disease with integrated traditional Chinese and western medicine.展开更多
Psoriasis is an immune-abnormal,chronic,proliferative skin disease determined by polygenic inheritance and induced by a number of environmental factors.It causes worldwide concern because of its high-prevalence,harmfu...Psoriasis is an immune-abnormal,chronic,proliferative skin disease determined by polygenic inheritance and induced by a number of environmental factors.It causes worldwide concern because of its high-prevalence,harmful and incurable characteristics.Over the years,Chinese medicine（CM） treatment of psoriasis has accumulated a wealth of clinical experience.Disease-syndrome combination, which achieves more satisfactory clinical effect,is the basis to highlight the special CM advantages in treating psoriasis.In this paper,we review the advantages of treating psoriasis with the combination of disease and syndrome,analyze the prospects of research on treating psoriasis combining disease with syndrome.We also make a point that there are several key points for the clinical research of combination of disease and syndrome.It can be expected that carrying out clinical research on the combination of disease and syndrome will help improve the clinical efficacy of medical treatment of psoriasis,which will be the main direction of research in the future.展开更多
股骨头坏死(osteonecrosis of the femoral head,ONFH)是骨科临床常见且难治性疾病,早期多无明显症状和体征,容易造成误诊和漏诊。“四辨”即辨病(辨病因病机、发生、发展和预后)、辨证(辨中医证型)、辨位(辨病邪所影响的局部与整体)、...股骨头坏死(osteonecrosis of the femoral head,ONFH)是骨科临床常见且难治性疾病,早期多无明显症状和体征,容易造成误诊和漏诊。“四辨”即辨病(辨病因病机、发生、发展和预后)、辨证(辨中医证型)、辨位(辨病邪所影响的局部与整体)、辨体(辨患者体质)相结合,是以四诊信息为基础的一种更加整体、规范的中医诊断模式;“三法”即内服中药、针药外治(中药热敷结合针刀疗法)、动静结合(康复过程中需动静结合)。“四辨三法”用于股骨头坏死的中医临床诊治,可实现早期精确诊断,有效防治股骨头坏死。展开更多
基金Supported by National Natural Science Foundation of China(81403189,81460628,81660705,81560690)Scientific Research Project of Higher Education in Guangxi Department of Education(YB2014182)
文摘Although the animal models of hepatic fibrosis developed by former researchers have pathological changes of hepatic fibrosis, they do not include charac- teristics of important TCM syndromes such as stagnation of qi, deficiency of qi, liver depression, phlegm-dampness and blood stasis because of single-factor model- ing. Animal models of hepatic fibrosis and animal models integrated disease and syndrome were reviewed, and several new types of integrated disease and syndrome animal models constructed by multiple-factor modeling method were evaluated, under the guidance of etiological theory of TCM. This kind of hepatic fibrosis model animals has dual characteristics of disease and syndrome. It is consistent with pathological characteristics of hepatic fibrosis in western medicine when replicating the basic characteristics accorded with TCM syndrome. Thus, the pathogenesis and pathogenic process of clinical disease and syndrome formation is simulated more ac- curately, providing a new platform and pathway for studying hepatic fibrosis disease with integrated traditional Chinese and western medicine.
基金Supported by the Financial Industry Technology Research and Development Program of Guangdong Province(No.201105)
文摘Psoriasis is an immune-abnormal,chronic,proliferative skin disease determined by polygenic inheritance and induced by a number of environmental factors.It causes worldwide concern because of its high-prevalence,harmful and incurable characteristics.Over the years,Chinese medicine（CM） treatment of psoriasis has accumulated a wealth of clinical experience.Disease-syndrome combination, which achieves more satisfactory clinical effect,is the basis to highlight the special CM advantages in treating psoriasis.In this paper,we review the advantages of treating psoriasis with the combination of disease and syndrome,analyze the prospects of research on treating psoriasis combining disease with syndrome.We also make a point that there are several key points for the clinical research of combination of disease and syndrome.It can be expected that carrying out clinical research on the combination of disease and syndrome will help improve the clinical efficacy of medical treatment of psoriasis,which will be the main direction of research in the future.
文摘股骨头坏死(osteonecrosis of the femoral head,ONFH)是骨科临床常见且难治性疾病,早期多无明显症状和体征,容易造成误诊和漏诊。“四辨”即辨病(辨病因病机、发生、发展和预后)、辨证(辨中医证型)、辨位(辨病邪所影响的局部与整体)、辨体(辨患者体质)相结合,是以四诊信息为基础的一种更加整体、规范的中医诊断模式;“三法”即内服中药、针药外治(中药热敷结合针刀疗法)、动静结合(康复过程中需动静结合)。“四辨三法”用于股骨头坏死的中医临床诊治,可实现早期精确诊断,有效防治股骨头坏死。
