Early Application Study of Intravenous Pain Pump Combined with Parecoxib Injection in Relieving Pain in Patients after Thoracoscopy

Objective: To explore the clinical effectiveness of combined use of intravenous pain pump with Parecoxib injection in alleviating pain in patients during the early postoperative period after thoracoscopic surgery. Methods: Eighty patients who underwent thoracoscopic surgery in a tertiary hospital were selected as the study subjects and randomly divided into two groups, with 40 patients in each group. The control group received routine postoperative treatment with intravenous pain pump, while the experimental group received Parecoxib in addition to the standard postoperative pain pump treatment. Visual Analog Scale (VAS) pain scores were used to evaluate postoperative pain relief in both groups, along with adverse reactions, postoperative complications, and patient satisfaction with pain relief. Results: Patients who received Parecoxib injection in addition to the routine use of intravenous pain pump had VAS pain scores lower than 3 points at 6 h, 12 h, 24 h, and 36 h postoperatively compared to those in the control group. The incidence of postoperative lung collapse, pleural effusion, and pulmonary infections was also significantly lower in the experimental group. The differences between the two groups were statistically significant (P Conclusion: Early combined use of Parecoxib injection in the early postoperative period after thoracoscopic surgery has shown good clinical efficacy. It can reduce the level of pain in patients, promote effective coughing and expectoration, facilitate early mobilization of patients, improve patient compliance, reduce complications, shorten hospital stay, and expedite patient recovery. Therefore, it is worth promoting the widespread clinical application of Parecoxib injection in this setting.

Effects of Combined Organic-inorganic Fertilization on Quality and Water Use Efficiency of Spring Maize under Equal Nitrogen Fertilization

The experiment was conducted in the abandoned land of Liangjia Village,Huayin City,Shaanxi Province from April to September 2019.The experimental crop was spring maize.A total of six treatments were set up in a randomized block design.The moisture content of the top 0-60 cm soil was determined regularly,and the yield and quality indices of maize at maturity were checked.The results show that:(i)combined organic-inorganic fertilization increased the yield of spring maize by 3%-8%.(ii)Compared with CK,fertilization treatments significantly improved the water use efficiency of spring maize,with an increase of 59.2%.The average water use efficiency of three combined organic-inorganic fertilization treatments was 27.81 kg/(ha·mm).Compared with CON,combined application of organic and inorganic fertilizers significantly improved the water use efficiency of spring maize,with an increase of 12.5%.(iii)The combined application of organic and inorganic fertilizers increased the moisture,total starch,crude protein and crude fat contents,and reduced crude fiber content of maize kernels.However,with the increase of the proportion of organic fertilizer,the crude protein content of maize kernels decreased.(iv)Yield of spring maize showed a significant parabolic relationship with soil water consumption.In summary,70%inorganic fertilizer+30%organic fertilizer is a scientific and reasonable way of fertilization.

Study on the Effect of Shuanghuanglian Powder Needle Combined with Cefoperazone and Sulbactam Sodium on Pseudomonas aeruginosa in Vitro

Objective: To explore the antibacterial activity of combined use of Shuanghuanglian and cefoperazone sulbactam sodium on resistant strains of Pseudomonas aeruginosa. Methods: The Pseudomonas aeruginosa strains which were sensitive and resistant to cefoperazone sulbactam sodium were selected to prepare different test bacterial solutions respectively;The experimental liquid of Shuanghuanglian and Cefoperazone Sulbactam Sodium were prepared separately and set as different test groups and control groups;The Drug Sensitivity Tests of Shuanghuanglian and cefoperazone sulbactam sodium at different concentration gradients which were used alone or used in combination were carried out for different strains with sensitivity and resistance, And use standard entry as a reference control. Result: The results of drug sensitivity test of Shuanghuanglian combined with Cefoperazone-Sulbactam sodium against the resistant strains of Pseudomonas aeruginosa were compared with the results of drug sensitivity test of the two separately used, and the difference was statistically significant (P 〈 0.05) [The drug sensitivity test results of Shuanghuanglian and cefoperazone sulbactam sodium to Pseudomonas aeruginosa resistant strains were statistically significant compared with the drug sensitivity test results of Shuanghuanglian and Cefoperazone Sulbactam Sodium used separately (P 〈 0.05)];There was a dependence between strains and concentration in the effect of the combination of the two drugs. Conclusion: The combination of Shuanghuanglian and cefoperazone sulbactam sodium has synergistic antibacterial or bactericidal effect on Pseudomonas aeruginosa resistant strains. .

Multi-output Gaussian Process Regression Model with Combined Kernel Function for Polyester Esterification Processes

In polyester fiber industrial processes,the prediction of key performance indicators is vital for product quality.The esterification process is an indispensable step in the polyester polymerization process.It has the characteristics of strong coupling,nonlinearity and complex mechanism.To solve these problems,we put forward a multi-output Gaussian process regression(MGPR)model based on the combined kernel function for the polyester esterification process.Since the seasonal and trend decomposition using loess(STL)can extract the periodic and trend characteristics of time series,a combined kernel function based on the STL and the kernel function analysis is constructed for the MGPR.The effectiveness of the proposed model is verified by the actual polyester esterification process data collected from fiber production.

Evaluation of Clinical Efficacy of Combined Use of Acupuncture and Medicine in Treating Sleep Disorder in Patients with Anxiety Disorder

[Objectives]To evaluate the clinical efficacy of combined acupuncture and medicine in the treatment of sleep disorders in patients with anxiety disorders.[Methods]A total of 300 anxiety patients with sleep disorders were randomly selected and divided into a research group and a control group,with 150 cases in each group.The control group was administered with western medicine,and the research group was treated with acupuncture and medicine to compare their clinical treatment effects.[Results]The total effective rate of treatment in the research group was significantly higher than that in the control group;after treatment,both the PSQI and SAS scores of the two groups were significantly reduced,and the reduction degree of the research group was higher than that of the control group,the difference was statistically significant(P<0.05).[Conclusions]Combined use of acupuncture and medicine to treat sleep disorders in patients with anxiety disorders has better curative effect and fewer adverse reactions,so it has high clinical application value.

Health Care Seeking Behaviour and Predictors of Combined Orthodox and Traditional Health Care Utilization among Households in Communities in Owerri, Imo State, Nigeria

Background: Health care seeking behaviour is a complex, dynamic and multidimensional process that involves a sequence of remedial actions that are influenced by the interaction between the individual, household and community with the intention of addressing perceived ill health. Objective: To determine health care seeking attitude and behaviour and the predictors of combined orthodox and traditional health care use among households in communities in Owerri, Imo State. Nigeria. Methods: A cross sectional design that used a multistage random sampling technique to select 500 participants from households in two communities in Owerri, Imo State. Data was collected using a pretested, semi structured questionnaire. Descriptive analyses were done with frequencies and summary statistics. Chi square statistics were computed to determine significant relationships and binary logistic regression was used to determine predictors of combined use. P was set at 0.05 significance level. Results: The results revealed that, while just more than half of the respondents (56.4%) had a moderate to good level of overall knowledge of health care, almost all of the respondents (96.2%) also had a moderate to good level of overall positive attitude towards seeking health care;with less than one third (29.4%) using combined orthodox and traditional health care treatments. It further revealed that, respondents who were female, traders and from households of polygamous families were significantly more likely to use combined orthodox and traditional health care treatments (p < 0.05) while those with a tertiary level of education, from households with a professional as head, having private water closet toilets and earning a monthly income of more than 50,000 Naira ($140) were significantly less likely to use combined orthodox and traditional health care treatments (p < 0.05). Conclusion: There is a need to be more sensitive to the realities of the combined use of orthodox and traditional treatments, as its use will be difficult to prevent because this behaviour is rooted in the traditional and cultural belief system of our societies.

Tectonic Implications of the Combined Use of Tectonomagmatic Geochemical Discrimination Diagrams and Indicators of Magma Flow Sense in Mafic Dykes

Geochemistry is a powerful tool to help characterize the tectonic setting of igneous rocks associations.However,when continental mafic dykes and flood basalts are the target most of the proposed geochemical discrimination diagrams fail to correctly classify them,i.e.many mafic

Combined Use of the Points Shenmai and Zhaohai for Treatment of Craniofacial Diseases

Shenmai (BL 62) and Zhaohai (KI 6), first recorded in A Classic of Acupuncture and Moxibustion (针灸甲乙经), are respectively the starting point of the YangqiaoChannel and the Yinqiao Channel, and they are two of the eight confluence points. Although records about the right-left compatible use of these two points can be found in documents, the same-side compatible use of them has never been heardabout. Inspired by the good therapeutic effects in the treatment of paralytic strabismus by means of the same-side compatible use of these two points1, the author has applied this compatible use of them in the treatment of craniofacial diseases and obtained obvious therapeutic effects. Some of the sample cases are reported in the following. ……

Combined use of retroperitoneal laparoscopy and bladder resectoscope to treat renal and ureteral tumor occurring at the same side of transplanted kidney (report of 5 cases)

To evaluate the operative characteristics and efficacy of retroperitoneoscopic resection of renal,ureter and partial bladder for the treatment of native renal pelvic and ureteral transitional cell cancer occurring at the same side of transplanted kidney.Methods In 5 cases of renal transplantation,there were 2 cases of right native renal pelvic cancer,1 case of right native renal pelvic and ureter cancer and 2 cases of right ureter cancer respectively.The transplanted kidney was in the same iliac fossa side of the tumor.All 5 patients were subjected to nephroureterectomy and bladder cuff excision by retroperitoneoscopic technique.Results Five operations were completed successfully.The operative time was 180 to 280 min,and the blood loss was 50 to 200 ml.The recovery of intestinal function after operation was 12 to 36 h.The urine output was 1 500 to 4 000 per day.Postoperative serum creatinine was still normal.The mean hospital stay after operation was 4.5 days.Conclusion Retroperitoneal laparoscopic nephroureterectomy and bladder cuff excision is a good method to treat the native renal pelvic and ureteral transitional cell cancer occurring at the same side of transplanted kidney.The procedure is safe and less invasive,which provides a good protection of transplanted kidney.12 refs.

Use of a Laser/TIG Combination for Surface Modification of Ti-6Al-4V Alloy

The surface modification of materials such as Ti-6Al-4V is necessary to improve their wear resistant properties for use in tribological applications. In this paper it is shown that a laser with low power and tungsten inert gas (TIG) can be combined together for surface modification of Ti-6Al-4V alloy, and when performed in a controlled atmosphere of pure nitrogen or a mixture of nitrogen and argon, can produce a wear-resistant surface alloy. Compared with laser processing, a cheaper surface modification process has been developed involving a shorter processing time, which is free of stringent requirements such as a vacuum system.

Combination Use of PFGE and Drug-resistant Analysis in the Epidemiological Investigation of Listeria Monocytogenes

Listeria monocytogenes is the pathogen of listeriosis and it causes severe infections like septicemia, encephalitis, and meningitis, especially in immunocompromised individuals, newborns, and pregnant women. Its wide distribution in the environment and ability to survive or even grow under adverse conditions has made L. monocytogenes an important public health concern and in food industry.

COMBINED TREATMENT OF HEBETIC SCANTY MENSTRUATION WITH ACUPUNCTURE AND DRUGS

According to a random distribution table, 60 cases of scanty menstruation patients were evenly divided into 3 groups: A) estrin (n = 20), B) acupuncture (n = 20), and C) acupuncture +estrin (n = 20) for comparing their therapeutic effect. Results showed that after treatment, 5 cases in estrin group, 12 cases in acupuncture group and 14 cases in acupuncture + estrin group respectively had an ovulation response. Statistical analysis displayed significant differences between acupuncture group or acupuncture + estrin group and estrin group. (P < 0.05, P <0.05 ); and between acupuneture and acupuncture + estrin groups in the estradiol level of the early phase of follicles in patients with ovulation and without ovulation (P < 0. 05, P < 0.01 ). The fact indicates a close interrelation between acupuncture-induced ovulatory effect and the estradiol level of the patient’s body.

The Study of Effect of Commercial Baicalin Combined with Cefoperazone Sulbactam Sodium on Pseudomonas aeruginosa in Vitro

Objective: To investigate the antibacterial effect of baicalin combined with cefoperazone-sulbactam sodium on drug-resistant strains of Pseudomonas aeruginosa. Method: Pseudomonas aeruginosa strains that are sensitive and resistant to cefoperazone-sulbactam sodium were selected to prepare different test bacterial solutions respectively;The test solutions of baicalin and cefoperazone sulbactam sodium were prepared respectively, and different test groups and control groups were set up;The drug sensitivity tests of different concentration gradients of baicalin and cefoperazone sulbactam sodium used alone and in combination were carried out for different sensitive and drug-resistant strains, and the standard strains were used as parallel control. Result: The drug susceptibility test results of the combined use of baicalin and cefoperazone-sulbactam against Pseudomonas aeruginosa drug-resistant strains were compared with the drug susceptibility results of the two used separately, and the difference was statistically significant (P Pseudomonas aeruginosa.

Control Effects of Bacillus subtilis DJ-6 and Pyraclostrobin Alone and in Combination Against Fusarium oxysporum

[Objective] This study was conducted to screen a synergistic biological fungicide complex to control Fusarium wilt, reducing the use of chemical pesticides. [Method] The inhibitory effects of Bacil us subtilis DJ-6 and pyraclostrobin alone or in combination at five ratios against Fusarium oxysporum were detected by mea-suring mycelium growth rate in laboratory tests. The growth promotion and disease control effect of combined or single use of 20% pyraclostrobin and 2 ×1011 cfu/g B. subtilis DJ-6 WP at 1∶1 000, 1∶2 000 and 1∶3 000 dilutions were detected in field trials. [Result] The EC50 values of combined use of B. subtilis DJ-6 and pyra-clostrobin at ratios of 1∶1, 1∶2, 1∶3, 1∶4 and 1∶5 against F. oxysporum were 5.311 5, 4.008 6, 3.570 6, 3.350 9 and 3.218 9 μg/ml, with the synergistic ratios （SR） of 2.28, 1.77, 1.53, 1.64, 1.11, among which the synergetic effect at 1∶1 was the best. The fungicidal activity of pyraclostrobin was greater than that of B. subtilis DJ-6 in laboratory tests. Field trials revealed that al the 1∶1 000, 1∶2 000 and 1∶3 000 dilu-tions of 20% pyraclostrobin·2×1011 cfu/g B. subtilis DJ-6 WP in combination, 1∶1 000 dilution of 1 ×1012 cfu/g B. subtilis DJ-6 WP and 1∶2 000 dilution of 250 g/L pyra-clostrobin EC promoted the growth of strawberry by increasing plant height, leaf petiole, leaf blade area and stem diameter. Among them, the treatments with 1∶1 000 and 1∶2 000 of 20% pyraclostrobin · 2×1011 cfu/g B. subtilis DJ-6 WP in combina-tion had better effects than other treatments. The control effects of al the treat-ments were measured 30 and 80 d after fungicide application. The control effects of 1∶1 000 dilution of 20% pyraclostrobin and 2×1011 cfu/g B. subtilis DJ-6 in combina-tion were up to 100% and 93.11%, which were higher than those in al other treat-ments. The second highest control effects were found in the treatment with 1∶ 2 000 dilution of 20% pyraclostrobin and 2×1011 cfu/g B. subtilis DJ-6 in combination, they were 92.49% and 86.49%, higher than those in other treatments except the 1∶1 000 dilution of 20% pyraclostrobin and 2 ×1011 cfu/g B. subtilis DJ-6 in combination. The control effects of 1∶3 000 dilution of 20% pyraclostrobin and 2×1011 cfu/g B. subtilis DJ-6 in combination were 82.61% and 72.42%, higher than those in treatment with 1∶1 000 dilution of 1×1012 cfu/g B. subtilis DJ-6 WP, but lower than those in treat-ment with 1∶2 000 dilution of 25% pyraclostrobin EC. [Conclusion] Al the results re-vealed that the combination use of 20% pyraclostrobin and 2 ×1011 cfu/g B. subtilis DJ-6 WP at 1∶1 000 to 1∶2 000 dilution had better control effect against strawberry Fusarium wilt.

Spectral Beam Combining of Fiber Lasers by Using Reflecting Volume Bragg Gratings

By employing three reflecting volume Bragg gratings, a near-infrared 4-channel spectral-beam-combining system is demonstrated to present 720 W combined power with a combining efficiency of 94.7%. The combined laser beam is near-diffraction-limited with a beam factor M^2-1.54. During this 4-channel beam-combining process, no special active cooling measures are used to evaluate the volume Bragg gratings as combining elements are under the higher power laser operation. Thermal expansion and period distortion are verified in a 2 k W 2-channel beam-combining process, and the heat issue in the transmission case is found to be more remarkable than that in the diffraction e-se. Transmitted and diffracted beams experience wave-front aberrations with different degrees, thus leading to distinct beam deterioration.

Land use suitability analysis for town development planning in Nanjing hilly areas: A case study of Tangshan new town, China

Land use suitability analysis plays an important role in sustainable land use and solving environmental problems caused by rapid urban development.A land use suitability mapping approach for town development planning in hilly areas was constructed based on two multi-criteria evaluation methods:Weighted Linear Combination(WLC)and Ordered Weighted Averaging(OWA),to comparatively evaluate and map land use suitability of Tangshan new town in Nanjing,China.Fourteen evaluation factors related to topographic,environmental,socio-economics and historical sites data were used as suitability criteria.The analytic hierarchy process(AHP)method and GIS techniques were integrated into the evaluation models to create the land use suitability map for town development planning.The results of WLC approach showed that 11.4%of the total area is highly suitable while the 48.6%is unsuitable.The results of WLC and OWA approach showed the distribution of degree of land use suitability is almost the same.The areas located at the southern and eastern flat regions are highly suitable for land use,whereas the areas close to the mountain forests,steep slopes,waters,and hot springs,have lower suitability for land use.Sensitivity analysis indicated that the suitability results of the two proposed methods are robust.Indirect validation was achieved by mutual comparison of suitability maps derived from the WLC and OWA methods.It demonstrated that the overall agreement is 90.81%and kappa coefficient is 0.81,indicating that both methods provide very similar spatial suitability distributions.By overlaying the resultant map with the previous master plan map of Tangshan new town,the overlay map once again indicated a satisfactory ecological fit between the two maps.At last,several recommendations are proposed aiming at improving the long-term town development plan for Tangshan new town.

Optimizing Nutrient Use Efficiency and Returns from Soybean Production under Smallholders in Three Agro-Ecologies of Malawi

Field trials were conducted to determine the economically optimum fertilizer rates for soybean production and for optimizing net profits in Dedza, Lilongwe and Salima Districts of Malawi. The effects of PK fertilizer rates on rain use efficiency (RUE), harvest index, agronomic use efficiency of phosphorous (AEP) and potassium (AEK), and value cost ratio (VCR) were evaluated. The applied diagnostic PK fertilizer rates significantly improved soybean grain yields, harvest index, rainwater use efficiency, AEP, AEK and returns to fertilizer use expressed as value cost ratio (VCR). However, the results differed significantly

An iterative approach to an integrated land use and transportation planning tool for small urban areas

There has been increasing interests in developing land use models for small urban areas for various planning applications such as air quality conformity analysis. The output of a land use model can serve as a major input to a transportation model; conversely, transportation model output can provide a critical input to a land use model. The connection between the two models can be achieved by an accessibility measure. This paper presents an iterative approach to solving a regression-based land use model and a transportation model with combined trip distribution- assignment. A case study using data from a small urban area is presented to illustrate the application of the proposed modeling framework. Tests show that the procedures can converge, and the modeling framework can be a valuable tool for planners and decision-makers in evaluating land use policies and transportation investment strategies.

Analysis of Drug Use in Outpatients with Hypertension Based on Real-World Study

Objective To explore the situation and trend of drug use in the treatment of hypertension in outpatient department of a hospital,and to provide reference for clinical rational drug use.Methods The data of 833 outpatients with hypertension in a hospital from July to December in 2020 were retrospectively analyzed.Results and Conclusion Among the 833 cases,calcium channel blocker(CCB)was the most frequently used drug(38.54%),followed by angiotensin receptor blocker(ARB)(13.81%),β-receptor blockers(β-RB)(10.44%),angiotensin-converting enzyme inhibitor(ACEI)(5.52%),and diuretics(0.72%).The combination rate was 37.09%(including single-pill combination,SPC).The highest rate was the combination of two drugs(28.21%),followed by the combination of three drugs(8.64%)and four drugs(1.20%).The DDDs and DDC of SPC were the highest among the six kinds of drugs.The use of antihypertensive drugs in outpatient department of the hospital is in line with the medication guidelines,but a small number of drugs are used irrationally,which needs further supervision and management.

Clinical Observation on the Combined Use of Acupuncture and Herbal Medicine for Treatment of Chloasma

Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma.Methods:Totally 60 patients were randomly divided into a treatment group of 30 cases,treated by acupuncture and herbal medicine,and a control group of 30 cases,administered Vitamin C and Vitamin E.The clinical effects were observed.Results:The total effective rate of the treatment group is 93.3%better than that of the control group(76.7%) ,the difference was significant(P<0.01) .Conclusion:Combined use of acupuncture and herbal medicine may yield definite therapeutic effects in treating chloasma patients.