Band 3, serving as an anion transporter, is the most abundant protein in the humanerythrocyte plasma membrane. It has two strucurally and functionally distinct domains.The membrane domain is responsible for the anion ...Band 3, serving as an anion transporter, is the most abundant protein in the humanerythrocyte plasma membrane. It has two strucurally and functionally distinct domains.The membrane domain is responsible for the anion exchange activity, while thecytoplasmic domain of Band 3 binds with components of the cytoskeleton (such asankyrin) to stabilize the cytoskeleton network. Although the cytoplasmic domain is展开更多
基金Department of Protein Engineering, Institute of Biophysics, the Chinese Academy of Sciences, Beijing 10010, China.
文摘Band 3, serving as an anion transporter, is the most abundant protein in the humanerythrocyte plasma membrane. It has two strucurally and functionally distinct domains.The membrane domain is responsible for the anion exchange activity, while thecytoplasmic domain of Band 3 binds with components of the cytoskeleton (such asankyrin) to stabilize the cytoskeleton network. Although the cytoplasmic domain is
