A randomized trail comparing primary percutaneous coronary intervention with a strategy of short-acting thrombolysis and immediate planned primary percutaneous coronary intervention in acute myocardial infarction

Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients referred for percutaneous coronary intervention (PCI).Methods Following aspirin and heparin, 166 patients were randomized to a 50 mg bolus of recombinant tissue type plasminogen activator(rt PA) or to a same volume sodium chloride injection followed by immediate primary PCI. The end points included patency rates on catheterization laboratory (cath lab) arrival, revascularization results when PCI was performed, complication rates, left ventricular function and restored patency rate following PCI. Results Patency on cath lab arrival was 64% with rt PA (34% TIMI 3,30% TIMI 2), while 31% of placebo (13% TIMI 3, 18% TIMI 2). There was no difference in the restored TIMI 3 rates of IRA between the two groups (85% vs 87%). No difference were observed in stroke or major bleeding. Left ventricular function was similar in both groups (52±9% vs 50±8%), but left ventricular ejection fraction fraction (LVEF) was higher with patent IRA (TIMI 3) on cath lab arrival than that of others (56±12% vs 48±10%).Conclusions Strategy thrombolytic regimens were compatible with subsequent PCI lead to more frequenc early recanalization (before cath lab arrival), which facilitates greater left ventricular function preservation with no augmentation of adverse events.

An Audio Zero-Watermark Scheme Based on Energy Comparing

Zero-watermark technique,embedding watermark without modifying carriers,has been broadly applied for copyright protection of images.However,there is little research on audio zerowatermark.This paper proposes an audio zero-watermark scheme based on energy relationship between adjacent audio sections.Taking use of discrete wavelet transformation(DWT),it gets power approximations,or energies,of audio segments.Then,it extracts the audio profile,i.e.the zero-watermark,according to the relative size of energies of consecutive fragments.The experimental results demonstrate that the proposed scheme is robust against general malicious attacks including noise addition,resampling,low-pass filtering,etc.,and this approach effectively solves the contradiction between inaudibility and robustness.

Comparing the rhythm and frequency of heart,breathing and knee movement in Tai Chi Chuan

Background:The basic exercise involved in TCC is a series of individual movements that are linked together in a continuous manner and that flow smoothly from one movement to another.Deep breathing and mental concentration are also required to achieve harmony

Preparative Resolution of Gatifloxacin Enantiomers with Pre-Column Esterification Strategy and Comparing Their Enantioselectivity to Bacteria and Antibody

Gatifloxacin （GFX） is a kind of chiral fluoroquinolones compound due to the methyl group at the C-3 position of the piperazine ring[1]. Although the enantiomers of GFX show similar levels of antimicrobial activity and pharmacokinetics[2], the other biological activities （i.e., toxicity or enantioselective recognition to various receptors in vivo） of GFX enantiomers have not yet been studied. With this in mind, we developed a rapid and cost-effective high performance liquid chromatographic （HPLC） separation procedure for GFX enantiomers with a pre-column esterification strategy.

Comparing of Aviation Network Structure of Mid-south,Northwest and Southwest of China Based on Hierarchical Index Model

In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and improve its structure,hierarchical index model of regional aviation network was established through dividing the aviation network into layers to research its structure characters.Data matrixes were defined to record the basic state of regional aviation network.Index matrixes were constructed to describe the quantitative features of regional aviation network.On the basis of these indexes,several structure indexes of all layers of aviation network were calculated to show the structure features of aviation network,such as ratio of passenger volume within the region with across the region,share rate of passenger volume among layers,ratio of average number of airline for each airport,ratio of average passenger volume for each airline and ratio of airline rate.According to the statistical data,similar structure of share rate of passenger volume among layers and average passenger volume for each airline in their regional aviation network was found after calculating.But on the side of ratio of passenger volume within the region with across the region,ratio of average number of airlines for each airport and ratio of airline rate were different.

Comparing the Effectiveness of Coatings on Carbide andCermet Cutting Tool Inserts

A series of metal cutting experiments was performed on a CNC lathe to evaluate the performance of various coatings on different tool substrates. The workpiece material was plain medium carbon steel and the cutting tool materials were carbide and cermet inserts coated with various single as well as multilayer coatings. Machining was done under various cutting conditions of speed and feed-rate, and for various durations of Cutting. The output parameters studied were the cutting forces (axial, radial and tangential), the surface roughness of the workpiece, as well as the tool wear (crater and flank wear). From these results, the performances of the various cutting inserts are evaluated and compared. Results show that cutting forces are significantly lower when using coated cermets than when using coated carbides although different coatings on the same substrate also result in different cutting forces. However, there is less difference in the surface roughness of the finished workpiece for the various coatings and substrates.

Comparing a small gravel-less perforated pipe leach fields (GPPLF) to a medium one in treating domestic sewage

There were obvious differences between a medium gravel-less perforated pipe leach fields and a small system in the treatment of demestic sewage with the change of influent quality. In small system, COD removal rate was 91%, ammonia nitrogen removal rate was 90%, total nitrogen was 58%. In medium system, COD removal rate was 86.07%, ammonia nitrogen removal rate was 45.3%, and total nitrogen was 48.2%. This paper studied on the differences. Its main reasons were as follows: differences in opening rate (perforated area account of the total area in infiltration pipe), air flow conditions, exterior environment, and wastewater distribution. Considering those problems, Solutions and applications for the development of GPPLF are given.

Comparing Coordination Abilities of 10-11 Years Old Girls Practicing Basketball and Rhythmic Gymnastic

The words---coordination, coordination abilities and coordination training are getting more and more popular among the coaches in different sports. The rhythm makes the movement logical, easy and correct done. The purpose of this study is to determine any difference between the coordination abilities of 10-11 years old gifts practicing basketball and rhythmic gymnastics. In that study, we have tested 40 girls at the age of 10-11 years practicing basketball and rhythmic gymnastic. We have tested them by 7 coordination tests. The results from the tests have been calculated in math-statistic methods and we have used descriptive statistic and t-test by Student with guaranteed probability Pt 〉 95 %. Ten-eleven old girls practicing rhythmic gymnastic have advantage against the girls practicing basketball in all 7 tests examining coordination abilities. The girls practicing rhythmic gymnastic, guaranteed by statistic, have better results in the balance and rhythmic abilities than the girls practicing basketball game. That statement is showing us that at this age the rhythmic gymnastic or elements from rhythmic gymnastic should be used for developing balance and rhythmic ability, which are very important for the basketball game.

Comparing High-resistance Grounding Method with Resonance Grounding Method for Large Generators

For large generators, the problem of high-resistance grounding method and the advantages of resonance, grounding method are discussed in detail, and an overall comparison is given in this paper. It is recommended that the latter should be adopted so as to increase the operation reliability of large generators and power systems.

A randomized double-blind multicenter study on comparing levonorgestrel and mifepristone for emergency contraception

Objective: To compare the efficacy and side effects of levonorgestrel and low dose mifepristone in emergency contraception. Method: The study is a randomized double--blind multicenter comparative trial. A total of 1, 276 women with unprotected intercourse within 72 hours were allocated to one of the two study groups. In the levonorgestrel (LNG) group, 0. 75 mg LNG was taken twice, 12 hours apart, whereas in the mifepristone (Mife) group, a single dose of 10 mg mifepristone was taken and a placebo 12 hours after. Follow--up visit was paid on the seventh day of the expected next menstruation to evaluate the contraceptive efficacy and side effects. Contraceptive efficacy was calculated by Dixon’s method. Result:In the LNG group 20 pregnancies occurred among 643 women, while in the Mife group 9 pregnancies occurred among 633 women. The pregnancy rates were 3. 10% and 1. 43% respectively. Contraceptive efficacy rate of preventing pregnancy was 59. 16% and 79. 73%, the difference was statistically significant (P<O. 05). The incidence of various side effects, which were mild, was less than 10%. There was no statistical difference between the two groups. The percentage of subjects who had their next menstruation 3 days earlier or later than their expected menstruation in LNG group and Mife group was 77. 7% and 78. 5% respectively. Conclusion: Use of levonorgestrel or low dose mifepristone for emergency contraception is effective and safe.

Reflexivity in the Transformation of Higher Education:Comparing Japan,South Korea,and Taiwan

The objective of this paper is to compare the transformation of higher educations in Japan,South Korea,and Taiwan.The higher education systems in these societies were established and transformed from homologous Japanese Imperial Universities,and developed toward various higher education systems intermediated by policies under international and domestic contexts.Using second hand data,the results show the common characteristics of these cases from state-led national elitism to market-led massification by means of privatization and commercialization.However,some differences exist in their finances resources,enrolment rates,policies for tuition fees and mostly important,job rewards for those who obtain higher education degrees,comparing to high school ones.The rise of reflexivity further suggests that the right of access to higher education has been changed from institutional limited opportunities,to the actors who decide when,why,and how to accept higher education.The facts imply that the states have to adjust and re-define their roles in higher education,and diverse programs and learning methods will be provided for multiple students in the future.

Practical Challenges in Comparing Chinese and American Local Government

Parts of China are an advanced industrial society with excellent public transportation, universities, industry, and other modern features; while other parts （geographically and functionally） remain a developing nation. For China, to build a stronger and more equitable society requires much work to develop governance at the local level. In pursuit of this goal, China actively seeks to learn lessons from abroad, including from American local government. This article examines the similarities and differences between these two nations and their systems of government toward the end of identifying potential challenges to Chinese efforts to learn from American-style local governance. This is grounded in policy transfer theory, which guides the discussion of how to learn from other jurisdictions--from other jurisdictions within the nation, from other points in time within the nation, and from other nations. Perhaps the ultimate questions are, ＂Should China continue efforts to learn from external models or focus its energy internally？＂ and ＂Does China need a more clearly defined governance model rather than its current approach that simultaneously allows and questions a high degree of decentralization （both within the party and the government）？＂ This paper seeks to add to that intellectual discourse by applying recent data and a conceptual framework.

What Isat Stake in Comparing the Literatures?

This paper will present and discuss a few questions raised in David Damrosch's Comparing the Literatures:Literary Studies in a Global Age,a book that,divided into chapters based on some selected keywords,develops relevant thematic nuclei,bringing to the fore literary authors,critics,and theorists.

Comparative transcriptome analysis between rhesus macaques(Macaca mulatta) and crab-eating macaques(M. fascicularis)

Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques(Macaca mulatta, MMU)and crab-eating macaques(M. fascicularis, MFA) serve as crucial nonhuman primate biomedical models with different phenotypes. To date, however, large-scale comparative transcriptome research between these two species has not yet been fully explored. Here, we conducted systematic comparisons utilizing newly sequenced RNA-seq data from84 samples(41 MFA samples and 43 MMU samples)encompassing 14 common tissues. Our findings revealed a small fraction of genes(3.7%) with differential expression between the two species, as well as 36.5% of genes with tissue-specific expression in both macaques. Comparison of gene expression between macaques and humans indicated that 22.6% of orthologous genes displayed differential expression in at least two tissues. Moreover,19.41% of genes that overlapped with macaque-specific structural variants showed differential expression between humans and macaques. Of these, the FAM220A gene exhibited elevated expression in humans compared to macaques due to lineage-specific duplication. In summary,this study presents a large-scale transcriptomic comparison between MMU and MFA and between macaques and humans. The discovery of gene expression variations not only enhances the biomedical utility of macaque models but also contributes to the wider field of primate genomics.

超声辅助与纤维支气管镜辅助经皮扩张气管切开术的对比研究

目的探讨超声辅助经皮扩张气管切开术的应用价值。方法回顾性分析2020年12月~2022年12月在甘肃省人民医院重症医学科行经皮扩张气管切开术患者56例,均经口气管插管后呼吸机辅助呼吸,根据不同的辅助方式分为超声辅助(超声组)31例和纤维支气管镜辅助(纤维支气管镜组)25例。结果与纤维支气管镜组比较,超声组术中氧合指数(PaO_(2)/FiO_(2))增高[(157.3±19.2)mmHg vs.(145.4±22.8)mmHg,t=2.117,P=0.039],分钟通气(MV)量增高[(7.3±0.8)L/min vs.(6.1±0.7)L/min,t=5.278,P<0.001],动脉血二氧化碳分压(PCO_(2))降低[(39.1±4.8)mmHgvs.(44.3±5.6)mmHg,t=-3.709,P<0.001],术后出血例数减少[0例vs.4例,χ^(2)=5.246,P=0.022]。结论超声组较纤维支气管镜组行经皮扩张气管切开术手术并发症少,安全性高。

低温等离子射频消融联合下鼻甲骨折外移术治疗阻塞性睡眠呼吸暂停低通气综合征的疗效观察

目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者接受低温等离子射频消融联合下鼻甲骨折外移术后睡眠及经鼻持续气道正压通气(nasal continuous positive airway pressure,nCPAP)治疗耐受性的改善情况。方法选择40例OSAHS合并双侧下鼻甲肥大的患者作为研究对象,均在局麻下接受下鼻甲低温等离子射频消融联合骨折外移术。术前及术后2周分别采用多导睡眠监测(PSG)、鼻阻力仪、autoCPAP呼吸机及视觉模拟量表(VAS)测定睡眠呼吸暂停低通气指数(AHI)、最低血氧饱和度(lowest oxygen saturation,LSaO_(2))、鼻气道阻力及nCPAP治疗耐受性。结果与术前比较,术后2周时患者AHI降低至(35.17±9.72)次/h,LSaO_(2)提高至(83.21±6.58)%,鼻气道阻力降低至(0.55±0.09)kPa·s/cm^(3),VAS评分升高至8.32±1.17,差异比较均有统计学意义(P均<0.05)。结论低温等离子射频消融联合下鼻甲骨折外移术能有效降低OSAHS患者的鼻阻力,提高nCPAP治疗的耐受性,改善OSAHS患者的睡眠情况。

Rice-wheat comparative genomics:Gains and gaps

Rice and wheat provide nearly 40%of human calorie and protein requirements.They share a common ancestor and belong to the Poaceae(grass)family.Characterizing their genetic homology is crucial for developing new cultivars with enhanced traits.Several wheat genes and gene families have been characterized based on their rice orthologs.Rice–wheat orthology can identify genetic regions that regulate similar traits in both crops.Rice–wheat comparative genomics can identify candidate wheat genes in a genomic region identified by association or QTL mapping,deduce their putative functions and biochemical pathways,and develop molecular markers for marker-assisted breeding.A knowledge of gene homology facilitates the transfer between crops of genes or genomic regions associated with desirable traits by genetic engineering,gene editing,or wide crossing.

Chromosome-level genome and population genomics of the intermediate horseshoe bat(Rhinolophus affinis)reveal the molecular basis of virus tolerance in Rhinolophus and echolocation call frequency variation

Horseshoe bats(genus Rhinolophus,family Rhinolophidae)represent an important group within chiropteran phylogeny due to their distinctive traits,including constant high-frequency echolocation,rapid karyotype evolution,and unique immune system.Advances in evolutionary biology,supported by high-quality reference genomes and comprehensive whole-genome data,have significantly enhanced our understanding of species origins,speciation mechanisms,adaptive evolutionary processes,and phenotypic diversity.However,genomic research and understanding of the evolutionary patterns of Rhinolophus are severely constrained by limited data,with only a single published genome of R.ferrumequinum currently available.In this study,we constructed a high-quality chromosome-level reference genome for the intermediate horseshoe bat(R.affinis).Comparative genomic analyses revealed potential genetic characteristics associated with virus tolerance in Rhinolophidae.Notably,we observed expansions in several immune-related gene families and identified various genes functionally associated with the SARS-CoV-2 signaling pathway,DNA repair,and apoptosis,which displayed signs of rapid evolution.In addition,we observed an expansion of the major histocompatibility complex class II(MHC-II)region and a higher copy number of the HLA-DQB2 gene in horseshoe bats compared to other chiropteran species.Based on whole-genome resequencing and population genomic analyses,we identified multiple candidate loci(e.g.,GLI3)associated with variations in echolocation call frequency across R.affinis subspecies.This research not only expands our understanding of the genetic characteristics of the Rhinolophus genus but also establishes a valuable foundation for future research.

Synergistic effects of Pleistocene geological and climatic events on complex phylogeographic history of widespread sympatric species of Megaloptera in East Asia

Unraveling the phylogeographic histories of species remains a key endeavor for comprehending the evolutionary processes contributing to the rich biodiversity and high endemism found in East Asia.In this study,we explored the phylogeographic patterns and demographic histories of three endemic fishfly and dobsonfly species(Neochauliodes formosanus,Protohermes costalis,and Neoneuromus orientalis)belonging to the holometabolan order Megaloptera.These species,which share a broad and largely overlapping distribution,were analyzed using comprehensive mitogenomic data.Our findings revealed a consistent influence of vicariance on the population isolation of Neoc.formosanus and P.costalis between Hainan,Taiwan,and the East Asian mainland during the early Pleistocene,potentially hindering subsequent colonization of the later diverged Neon.orientalis to these islands.Additionally,we unveiled the dual function of the major mountain ranges in East Asia,serving both as barriers and conduits,in shaping the population structure of all three species.Notably,we demonstrated that these co-distributed species originated from Southwest,Southern,and eastern Central China,respectively,then subsequently migrated along multi-directional routes,leading to their sympatric distribution on the East Asian mainland.Furthermore,our results highlighted the significance of Pleistocene land bridges along the eastern coast of East Asia in facilitating the dispersal of mountain-dwelling insects with low dispersal ability.Overall,this study provides novel insight into the synergistic impact of Pleistocene geological and climatic events in shaping the diversity and distribution of aquatic insects in East Asia.