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Study on the Complex Prescription Compatibility Law of the Cold and Hot Nature of Mahuang Decoction(麻黄汤) and Its Categorized Formulae Based on the Cold-Hot Pad Differentiating Assay 被引量:1
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作者 贾雷 赵艳玲 +5 位作者 王伽伯 邹文俊 李瑞生 杨宏博 程丹红 肖小河 《Chinese Journal of Integrative Medicine》 SCIE CAS 2011年第4期290-295,共6页
Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with differe... Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with different hot/cold natures.Methods:Oxygen consumption of mice was determined among three groups:MHD,MXSGD and the control;a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD,MXSGD,and their compositions. Meanwhile,the total anti-oxidant capability(T-AOC) activity were detected.Results:After administration of MHD, the mice showed increased oxygen consumption(P0.01).Compared with MHD group,the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P0.05).There was no significant difference(P0.05) among the remaining rates of MXSGD,MXSGD with high dose Gypsum Fibrosum(MXHGF) group,and MXSGD with low dose Gypsum Fibrosum(MXLGF) group mice.Compared with the MHD group,T-AOC activity of the mice in the Consensus Compositons group was significantly decreased(P=0.0494).Compared with the MXSGD group,T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly(P=0.0013).Conclusions:The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature.The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions.However,increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD. 展开更多
关键词 Mahuang Decoction and its categorized formulae cold and hot nature of Chinese drugs complex prescription compatibility law of Chinese medicine cold-hot pad differentiating assay
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Mining the rules of acupoint selection and manipulation scheme of massage in reducing or substituting drug treatment of simple obesity based on association rules and entropy cluster analysis
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作者 Xiao-Lin Zhang Cao Di +2 位作者 Long Zhang Nuo-Xin Pei Ming-Jun Liu 《Medical Data Mining》 2021年第2期9-19,共11页
Based on the data mining of clinical literature,we analyzed the characteristics of Acupoint Selection and manipulation in the clinical treatment of“simple obesity”,in order to optimize the compatibility of clinical ... Based on the data mining of clinical literature,we analyzed the characteristics of Acupoint Selection and manipulation in the clinical treatment of“simple obesity”,in order to optimize the compatibility of clinical acupoints,simplify the manipulation,and summarize the core prescription of Massage in the treatment of simple obesity.Methods:First we search and screen the clinical literature of Chinese Massage therapy for“simple obesity”by scholars at home and abroad.Then we analyze the Acupoint Selection and manipulation rules of Chinese Massage therapy for“simple obesity”by using data mining technology and traditional Chinese Medicine Inheritance assistant system.Finally we obtain the optimal new prescription based on complex system entropy clustering and unsupervised entropy hierarchical clustering analysis.Results:Fifty-seven prescriptions meeting the inclusion criteria were selected,including TIANSHU(ST25)(36),ZHONGWAN(RN12)(32),GUANYUAN(RN4)(30),ZUSANLI(ST36)(27),QIHAI(RN6)(23),“Stomach Meridians”(10),“Spleen Meridians”(8),Renmai(7),Abdomen(36),Umbilicus(8),Pressing(33),Holding(27),Pressing(26),and get 4 core Prescriptions like ST25-RN12-Renmai-Stomach Meridians-Abdominal Rub-Rubbing-Pushing thumb-Rubbing-Palm Pushing-Thumb Point Acupuncture-Palm Vibration and 4 new prescription of Massage manipulation for the treatment of simple obesity.Conclusion:The results of clinical diagnosis and treatment data are mined and analyzed by traditional Chinese medicine inheritance assistant system.The acupoint compatibility,manipulation rules and core prescriptions obtained can provide statistical basis and references for clinical Massage manipulation in the treatment of simple obesity. 展开更多
关键词 Simple obesity Data mining Manipulation Aacupoints Traditional Chinese Medicine Inheritance assistant platform compatibility law Core prescription
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Study of the Distribution Patterns of the Constituent Herbs in Classical Chinese Medicine Prescriptions Treating Respiratory Disease by Data Mining Methods 被引量:9
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作者 Xian-jun Fu 付先军 (11090) (21090) Xu-xia Song 宋旭霞 (31090) +1 位作者 Lin-bo Wei 魏陵博 (21090) Zhen-guo Wang 王振国 (11090) 《Chinese Journal of Integrative Medicine》 SCIE CAS 2013年第8期621-628,共8页
Objective: To provide the distribution pattern and compatibility laws of the constituent herbs in prescriptions, for doctor's convenience to make decision in choosing correct herbs and prescriptions for treating res... Objective: To provide the distribution pattern and compatibility laws of the constituent herbs in prescriptions, for doctor's convenience to make decision in choosing correct herbs and prescriptions for treating respiratory disease. Methods: Classical prescriptions treating respiratory disease were selected from authoritative prescription books. Data mining methods (frequent itemsets and association rules) were used to analyze the regular patterns and compatibility laws of the constituent herbs in the selected prescriptions. Results: A total of 562 prescriptions were selected to be studied. The result exhibited that, Radix g/ycyrrhizae was the most frequently used in 47.2% prescriptions, other frequently used were Semen armeniacae amarum, Fructus schisandrae Chinese, Herba ephedrae, and Radix ginseng. Herbal ephedrae was always coupled with Semen armeniacae amarum with the confidence of 73.3%, and many herbs were always accompanied by Radix g/ycyrrhizae with high confidence. More over, Fructus schisandrae Chinese, Herba ephedrae and Rhizoma pinelliae was most commonly used to treat cough, dyspnoea and associated sputum respectively besides Radix glycyrrhizae and Semen armeniacae amarum. The prescriptions treating dyspnoea often used double herb group of Herba ephedrae & Radix glycyrrhizae, while prescriptions treating sputum often used double herb group of Rhizoma pinel/iae & Radix glycyrrhizae and Rhizoma pinelliae & Semen armeniacae amarum, triple herb groups of Rhizoma pinelliae & Semen armeniacae amarum & Radix glycyrrhizae and Pericarpium citri reticu/atae & Rhizoma pine/liae & Radix glycyrrhizae. Couclusioas: The prescriptions treating respiratory disease showed common compatibility laws in using herbs and special compatibility laws for treating different respiratory symptoms. These principle patterns and special compatibility laws reported here could be useful for doctors to choose correct herbs and prescriptions in treating respiratory disease. 展开更多
关键词 multi-herb recipes compatibility laws respiratory disease data mining methods
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