关于Concordance Process与企业竞争优势的探索

介绍了由韩国仁荷大学李庆焕教授于2001年提出的竞争战略理论Concordance Process,认为企业取得竞争优势的关键在于如何大量有效地发挥和利用权利的五个基本属性,即创造属性、保存属性、支配属性、归属属性以及结合属性。

语法一致(grammatical conaord)与概念一致(notional concord)

根据“概念一致”的原则,there's+复数名词是“'s”用法的一种发展趋势。

基于局部self-concordant障碍函数的全牛顿步多项式时间算法(英文)

由Nesterov和Nemirovski^([4])创立的self-concordant障碍函数理论为解线性和凸优化问题提供了多项式时间内点算法.根据self-concordant障碍函数的参数,就可以分析内点算法的复杂性.在这篇文章中,我们介绍了基于核函数的局部self-concordant障碍函数,它在线性优化问题的中心路径及其邻域内满足self-concordant性质.通过求解此障碍函数的局部参数值,我们得到了求解线性规划问题的基于此局部Self-concordant障碍函数的纯牛顿步内点算法的理论迭代界.此迭代界与目前已知的最好的理论迭代界是一致的.

Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis

To determine the possible role of the epigenetic mechanisms in carcinogenesis of the hepatocellular carcinoma,we methylation-profiled the promoter CpG islands of twenty four genes both in HCC tumors and the neighboring non-cancerous tissues of twenty eight patients using the methylation-specific PCR (MSP) method in conjunction with the DNA sequencing. In comparison with the normal liver tissues from the healthy donors, it was found that while remained unmethylated the ABL, CAV, EPO, GATA3, LKB 1, NEP, NFL, NIS and p27KIP1 genes, varying extents of the HCC specific hypermethylation were found associated with the ABO, AR, CSPG2, cyclin al, DBCCRl,GALR2, IRF7, MGMT, MT1A, MYOD1, OCT6, p57KIP2, p73, WT1 genes, and demethylation with the MAGEA1 gene, respectively. Judged by whether the hypermethylated occurred in HCC more frequently than in their neighboring normal tissues, the hypermethylation status of the AR, DBCCR1, IRF7, OCT6, and p73 genes was considered as the event specific to the late stage, while that the rest that lacked such a distinguished contrast, as the event specific to the early stage of HCC carcinogenesis. Among all the clinical pathological parameters tested for the association with, the hypermethylation of the cyclin al gene was more prevalent in the non-cirrhosis group (P=0.021) while the hypermethylated p 16INK4a gene was more common in the cirrhosis group (P=0.017). The concordant methylation behaviors of nineteen genes, including the four previously studied and their association with cirrhosis has been evaluated by the best subgroup selection method. The data presented in this report would enable us to shape our understanding of the mechanisms for the HCC specific loss of the epigenetic stability of the genome, as well as the strategy of developing the novel robust methylation based diagnostic and prognostic tools.

Understanding of chemoprophylaxis and concordance in inflammatory bowel disease

AIM:To assess patients' understanding for the reasons for taking 5-aminosalicylic acid or ursodeoxycholic acid as chemoprophylaxis against colorectal carcinoma associated with in? ammatory bowel disease (IBD). METHODS: A questionnaire-based study using a 5 point opinion scale was performed. One hundred and ninety-two patients with colitis only and 74 patients with primary sclerosing cholangitis and IBD were invited to take part. RESULTS: Overall response rate was 58%. Sixtyfour percent of patients claimed full concordance with chemoprophylaxis for maintenance of remission. Eightyfour percent of patients considered daily concordance during remission to be very important. Seventy-five percent stated they understood the reasons for taking the drugs. However, only 50% of the patients were aware of any link of their condition to bowel cancer. Seventy-nine percent of patients felt their concordance and understanding would be improved if they were informed of the chemoprophylactic potential of the medication.

Magnetic resonance imaging and Crohn's disease endoscopic index of severity: Correlations and concordance

AIM To examine the correlation between magnetic resonance imaging(MRI) and endoscopic index of severity(CDEIS) in patients with Crohn's disease(CD).METHODS This was a retrospective study of 104 patients with CD that were treated at the Ruijin Hospital between March 2015 and May 2016. Among them, 61 patients with active CD were evaluated before/after treatment. MRI and endoscopy were performed within 7 d. CDEIS was evaluated. MRI parameters included Ma RIA scores, total relative contrast enhancement(tRCE), arterialRCE(aRCE), portalRCE(pRCE), delay phaseRCE(dRCE), and apparent diffusion coefficient. The correlation and concordance between multiple MRI findings and CDEIS changes before and after CD treatment were examined.RESULTS Among the 104 patients, 61 patients were classified as active CD and 43 patients as inactive CD. Gender, age, disease duration, and disease location were not significantly different between the two groups(all P > 0.05). CRP levels were higher in the active group than in the inactive group(25.12 ± 4.12 vs 5.14 ± 0.98 mg/L, P < 0.001). Before treatment, the correlations between CDEIS and MaRIAs in all patients were r = 0.772 for tRCE, r = 0.754 for aRCE, r = 0.738 for pRCE, and r = 0.712 for dRCE(all MaRIAs, P < 0.001), followed by MRI single indexes. Among the active CD patients, 44 cases were remitted to inactive CD after treatment. The correlations between CDEIS and MaRIAs were r = 0.712 for aRCE, r = 0.705 for tRCE, r = 0.685 for pRCE, and r = 0.634 for dRCE(all MaRIAs, P < 0.001).CONCLUSION Arterial Ma RIA should be an indicator for CD follow-up and dynamic assessment. CD treatment assessment was not completely concordant between CDEIS and MRI.

A Brief Study of Concord in English

The English language is different from the Chinese language in many ways.In Chinese there is noconcord,while in English verbs must be in agreement with subjects in person and number: a pronoun must be in agreement with the noun it refers to;elements in parallel structures must be in agreement with one another,therefore concord in English is quite important.We can say without exaggeration that one cannot produce a single sentence in English if there is no concord.This article is going to deal with concord in English by giving some principles supported by examples.

What's in a name? Compliance, adherence and concordance in chronic psychiatric disorders

About half or more of the patients with chronic psychiatric illnesses, either do not take their medications correctly, or completely stop taking them. The problem of poor initial compliance or adherence is often compounded by a continued decline in compliance/adherence over time. The failure to take medicines, adversely affects the outcome of treatment, and places a huge burden of wasted resources on the society. Three terms have been used to describe medication-taking among patients with chronic psychiatric disorders. Compliance is defined as "the extent to which the patient's behaviour matches the prescriber's recommendations". Though compliance has been frequently employed to describe medication-taking behaviour, it has proved problematic because it refers to a process where the clinician decides on a suitable treatment, which the patient is expected to comply with unquestioningly. Studies over the past few decades have emphasized the importance of patients' perspectives in medicationtaking, based on their own beliefs, their personal circumstances, the information and resources available for them. Adherence has been used as a replacement for compliance in an effort to place the clinician-patient relationship in its proper perspective. Adherence refers to a process, in which the appropriate treatment is decided after a proper discussion with the patient. It also implies that the patient is under no compulsion to accept a particular treatment, and is not to be held solely responsible for the occurrence of non-adherence. Adherence has been defined as "the extent to which a person's behaviour, taking medication, following a diet, and/or executing lifestyle changes, corresponds with agreed recommendations from a health care provider". To overcome certain problems in the concept of adherence, a third term concordance has been used. The concept of concordance has evolved from a narrower view, emphasizing an agreement between the clinician and the patient, which takes into account each other's perspective on medication-taking, to a broader process consisting of open discussions with the patient regarding medication-taking, imparting information and supporting patients on long-term medication. It is a process, which entertains patients' views on medicationtaking, and acknowledges that patients' views have to be respected even if they make choices, which appear to be in conflict with the clinician's views. Although none of these terms are ideal solutions to understanding the complex process of medication-taking behaviour of patients, the move from compliance to adherence and concordance represents genuine progress in this field, which puts the patient's perceptions at the centre of the whole process.

Concordance between bio-impedance analysis and clinical score in fluid-status assessment of maintenance haemodialysis patients: A single centre experience

BACKGROUND The burden of chronic kidney disease(CKD)is rising rapidly globally.Fluid overload(FO),an independent predictor of mortality in CKD,should be accurately assessed to guide estimation of the volume of fluid to be removed during haemodialysis(HD).Clinical score(CS)and bio-impedance analysis(BIA)have been utilized in assessment of FO and BIA has demonstrated reproducibility and accuracy in determination of fluid status in patients on HD.There is need to determine the performance of locally-developed CSs in fluid status assessment when evaluated against BIA.AIM To assess the hydration status of patients on maintenance HD using BIA and a CS,as well as to evaluate the performance of that CS against BIA in fluid status assessment.METHODS This was a single-centre,hospital-based cross-sectional study which recruited adult patients with CKD who were on maintenance HD at Kenyatta National Hospital.The patients were aged 18 years and above and had been on maintenance HD for at least 3 mo.Those with pacemakers,metallic implants,or bilateral limbs amputations were excluded.Data on the patients’clinical history,physical examination,and chest radiograph findings were collected.BIA was performed on each of the study participants using the Quantum®II bio-impedance analyser manufactured by RJL Systems together with the BC 4®software.In evaluating the performance of the CS,BIA was considered as the gold standard test.A 2-by-2 table of the participants’fluid status at each of the CS values obtained compared to their paired BIA results was constructed(either++,+-,--or-+for FO using the CS and BIA,respectively).The results from this 2-by-2 table were used to compute the sensitivity and specificity of the CS at the various reference points and subsequently plot a receiver operating characteristic(ROC)curve that was used to determine the best cut-off point.Those above and below the best CS cut-off point as determined by the ROC were classified as being positive and negative for FO,respectively.The proportions of participants diagnosed with FO by the CS and BIA,respectively,were computed and summarized in a 2-by-2 contingency table for comparison.McNemar’s chi-squared test was used to assess any statistically significant difference in proportions of patients diagnosed as having FO by CS and BIA.Logistic regression analysis was conducted to assess whether the variables for the duration of dialysis,the number of missed dialysis sessions,advisement by health care professional on fluid or salt intake,actual fluid intake,the number of anti-hypertensives used,or body mass index were associated with a patient’s odds of having FO as diagnosed by BIA.RESULTS From 100 patients on maintenance HD screened for eligibility,80 were recruited into this study.Seventy-one(88.75%)patients were fluid overloaded when evaluated using BIA with mean extracellular volume of 3.02±1.79 L as opposed to the forty-seven(58.25%)patients who had FO when evaluated using the CS.The difference was significant,with a P value of<0.0001(95%confidence interval:0.1758-0.4242).Using CS,values above 4 were indicative of FO while values less than or equal to 4 denoted the best cut-off for no FO.The sensitivity and specificity for the CS were 63%and 78%respectively.None of the factors evaluated for association with FO showed statistical significance on the multivariable logistic regression model.CONCLUSION FO is very prevalent in patients on chronic HD at the Kenyatta National Hospital.CS detects FO less frequently when compared with BIA.The sensitivity and specificity for the CS were 63%and 78%respectively.None of the factors evaluated for association with FO showed statistical significance on the multivariable logistic regression model.

On the Principle of Notional Concord in English

According to logical relation,a complete English sentence is usually made up by two major parts that are the subject and the predicate,and the subject and the predicate formally have one kind of corresponding relations in the syntactic constitution.The relation is also called the number concord.Generally speaking,the principle of subject and predicate concord mainly obeys three principles.Here we mainly have a discuss on the principle of Notional Concord.

Spousal concordance in academic achievements and IQ: A principal component analysis

Assortative mating, the tendency for mate selection to occur on the basis of similar traits plays an essential role in understanding the genetic variation on academic achievements and intelligence (IQ), it is also an important mechanism explaining spousal concordance. We used a subset of The Collaborative Study on the Genetics of Alcoholism sample to study the mating patterns in 84 pairs of spouses from Caucasian families with their academic achievements (reading, spelling, arithmetic, vocabulary and comprehension) and IQ (verbal IQ, performance IQ and full scale IQ). Simple correlation analysis showed that 6 of these 8 traits revealed evidence of spousal correlation (P < 0.05). The first principal component (PC1) of husbands explains 73.61% for the variation in the eight variables, which has high loadings from reading, spelling, arithmetic, verbal IQ and full scale IQ while PC1 of wives explains 72.86% for the variation in the eight variables, which has high loadings from reading, spelling, verbal IQ and full scale IQ. There was highly significant positive correlation between spouses by PC1 (P < 0.0001). The new variable PC1 may be important in spousal concordance and mate selection in society and act upon achievements and intelligence levels.

Decomposition of Independence Using the Logit Uniform Association Model and Equality of Concordance and Discordance for Two-Way Classifications

For two-way contingency tables with ordered categories, the present paper gives a theorem that the independence model holds if and only if the logit uniform association model holds and equality of concordance and discordance for all pairs of adjacent rows and all dichotomous collapsing of the columns holds. Using the theorem, we analyze the cross-classification of duodenal ulcer patients according to operation and dumping severity.

The effect of acculturation in the concordance of oral health related quality of life in Latino children and their parents

The Latino population is the fastest growing and the largest minority group in the United States comprising 16% of the population younger than 18 years of age. Yet, little is known about the effect of acculturation in oral health related quality of life in Latino children and their parents. Objective: The objective of this study was to assess the effect of acculturation in parent and child’s perceptions of the child’s oral health status and oral health related quality of life (OHRQoL) as well as the effect in the concordance between children and parents/caregivers. Method: Sixty-three Latino children between the ages of 8 and 15, and their parents were recruited from the waiting room at the University of California, San Francisco Orthodontic and Pediatric Clinics. Parent and children each separately completed the Child Oral Health Impact Profile questionnaire (COHIP) for children and COHIP for parent/caregiver. Results: Of the sixty-three children, fifteen children (23.8%) had a more negative perception of their oral health than their parents whereas twenty-three children (36.5%) had a more positive perception. In terms of agreement between children and parents, questions about oral health showed the lowest level of agreement (34.9%) and self-image questions the highest (55.6%). Conclusion: The study findings indicate that the more acculturated the child, the more negative their perception of their oral health. The level of disagreement between parent and child, underscores the importance of obtaining both the child and parent OHRQoL perceptions.

Concordance between Clinical and Histopathological Diagnoses at Komfo Anokye Teaching Hospital Oral and Maxillofacial Unit

Background: Accurate diagnosis of orofacial tumours is important as this determines the treatment options as well as the eventual treatment outcome. Agreement between clinical and histopathological diagnosis becomes important in this regard. Aims: The aim was to determine the level of agreement between clinical and histopathology diagnosis of orofacial lesions. Method: This is a retrospective study of all histopathology reports seen at KATH maxillofacial unit. Thedata collected included, clinical diagnosis and histological diagnosis. Results: A total of 567 histopathology reports were evaluated. The percentage of agreement between clinical and histopathological diagnosis was 62.8%. Conclusion: The agreement between clinical and histopathological diagnosis was high. However clinicians cannot rely on only the clinical diagnosis in managing patients.

Concordance to the Poems of Kyriakos Charalambides Through the ΑntConc Application With Reference Text—The “Sweet Preserves”

This study is based on the combination of the following three primary pylons:(1)Literature;(2)Information—Communication Technology;(3)Utilization of digital means in the educational approach.The objective of this project is the utilization of the concordance with the help of AntConc application in the educational approach and specifically in the subject of Modern Greek literature.With the contribution of the above application,the educational process makes it more effective to comprehend a particularly hard kind of literature such as poetry.Thus,Kyriakos Charalambides’1 poetry can be approached in both a different and an imaginative way,compared to the traditional textual way and as a result poetry can become more attractive for the students.The project is focused on the poetic work of Kyriakos Charalambides,which consists of thirteen collections of poems.The reference text,which is included in the textbook“Modern Greek Texts”taught in the 2nd Grade of High School and is part of the curriculum,is a poem called“Sweet Preserves”(Charalambides,2000).The objective is to investigate whether in practice and particularly in the subject of Modern Greek literature,the above mentioned application can be utilized through the search of the literal type“soil”,through AntConc application for tracing the appearance frequency of this word and by extension the highlighting of this thematic motif in the poetic work of Kyriakos Charalambides.Finally,in order that both the students’response(whether the objective was reached and the educational mediations were successful)and a certain level of awareness have been achieved,a questionnaire was distributed among the students and the students’answers were decoded through a specific type of software called SPSS so that the relevant outcomes were extracted.

Polynomial-time interior-point algorithm based on a local self-concordant finite barrier function

The choice of self-concordant functions is the key to efficient algorithms for linear and quadratic convex optimizations, which provide a method with polynomial-time iterations to solve linear and quadratic convex optimization problems. The parameters of a self-concordant barrier function can be used to compute the complexity bound of the proposed algorithm. In this paper, it is proved that the finite barrier function is a local self-concordant barrier function. By deriving the local values of parameters of this barrier function, the desired complexity bound of an interior-point algorithm based on this local self-concordant function for linear optimization problem is obtained. The bound matches the best known bound for small-update methods.

Mezzera公司开发出CONCORD型水洗机

Mezzera公司是一家著名的纺织机械生产商,其拳头产品是一系列对纺织品进行无张力湿处理的机器.生产的产品有:染色机、前处理设备、漂白设备及染色和印花后的水洗设备.

尿游离轻链与尿总轻链检测在尿轻链定量监测中的价值比较

目的:探讨新型尿游离轻链(urine free light chain,uFLC)检测在尿轻链定量监测方面是否优于传统尿总轻链(urine total light chain,uTLC)检测。方法:收集2022年1月至2023年3月间上海交通大学医学院附属瑞金医院的280例患者(包括浆细胞疾病患者153例和非浆细胞疾病患者137例)的血、尿配对样本,共458例次。应用卡方检验、McNemar配对检验和Spearman相关性分析等方法,统计检测的uFLC和uTLCκ值、λ值、κ/λ比值结果,并分析其与尿免疫固定电泳(urine immunofixation electrophoresis,uIFE)、血游离轻链(serum free light chain,sFLC)等检测结果之间的阳性相符率及相关性。结果:102例次uIFE阳性的样本中,88.2%(90/102)的样本有uFLCκ/λ比值异常,87.3%(89/102)的样本有uTLCκ/λ比值异常(P<0.001)。在183例次sFLCκ/λ比值异常的样本中,65.6%(120/183)的样本存在uFLCκ/λ比值异常,51.4%(94/183)的样本存在uTLCκ/λ比值异常(P<0.001)。457例次同时检测了uFLC和uTLC的样本中,164例次(35.9%)的uFLCκ/λ比值异常,123例次(26.9%)的uTLCκ/λ比值异常(P<0.001)。uFLC检测与uTLC检测的相应κ值、λ值、κ/λ比值之间均有着较强的相关性(r值分别为0.849、0.697和0.648,P<0.001);uFLC检测与sFLC检测的相应κ值、λ值、κ/λ比值之间的相关系数r值分别为0.628、0.552和0.640(P<0.001);而uTLC与sFLC检测的κ值、λ值、κ/λ比值之间的相关系数r值分别为0.520、0.533和0.551(P<0.001),均为中等相关。与uTLC与sFLC结果之间的相关性相比,uFLC与sFLC结果间的相关性更强。结论:uFLC检测在尿轻链定量监测方面较uTLC检测更灵敏,其结果与uIFE及sFLC等检测结果间的阳性相符率及相关性更高,能更客观地反映尿轻链的定量,在临床尿轻链定量监测中,可优先行uFLC检测。

精神专科医院男护士工作投入与反刍思维、自我和谐的相关性研究

目的调查精神专科医院男护士工作投入、反刍思维与自我和谐现状,分析其工作投入影响因素。方法于2021年8月,采用一般资料调查问卷、工作投入量表、反刍思维量表和自我和谐量表对北京市某精神专科医院138名男护士进行调查。采用SPSS 21.0软件对数据进行统计分析,采用Pearson相关分析法进行相关性分析,采用多元线性回归分析法分析男护士工作投入影响因素。结果精神专科医院男护士工作投入总分为(73.95±22.30)分,反刍思维总分为(36.85±12.06)分,自我和谐总分为(95.57±18.44)分。自我与经验不和谐、自我刻板性、反刍思维与工作投入呈负相关(r均<0,P均<0.05),自我灵活性与工作投入呈正相关(r>0,P<0.05)。自我灵活性、自我刻板性、反省深思、症状反刍是精神专科医院男护士工作投入的影响因素。结论反刍思维、自我和谐均对精神专科医院男护士工作投入水平有影响。精神专科医院男护士未“陷入”反刍思维,但工作投入和自我和谐水平有待改善。