Genetic Algorithm Optimization Design of Gradient Conformal Chiral Metamaterials and 3D Printing Verifiction for Morphing Wings

This paper proposes a gradient conformal design technique to modify the multi-directional stiffness characteristics of 3D printed chiral metamaterials,using various airfoil shapes.The method ensures the integrity of chiral cell nodal circles while improving load transmission efficiency and enhancing manufacturing precision for 3D printing applications.A parametric design framework,integrating finite element analysis and optimization modules,is developed to enhance the wing’s multidirectional stiffness.The optimization process demonstrates that the distribution of chiral structural ligaments and nodal circles significantly affects wing deformation.The stiffness gradient optimization results reveal a variation of over 78%in tail stiffness performance between the best and worst parameter combinations.Experimental outcomes suggest that this strategy can develop metamaterials with enhanced deformability,offering a promising approach for designing morphing wings.

Correcting dynamic residual aberrations of conformal optical systems using AO technology

This paper analyses the dynamic residual aberrations of a conformal optical system and introduces adaptive optics （AO） correction technology to this system. The image sharpening AO system is chosen as the correction scheme.Communication between MATLAB and Code V is established via ActiveX technique in computer simulation.The SPGD algorithm is operated at seven zoom positions to calculate the optimized surface shape of the deformable mirror.After comparison of performance of the corrected system with the baseline system,AO technology is proved to be a good way of correcting the dynamic residual aberration in conformal optical design.

Nucleic Acid Probes for Single-Molecule Localization Imaging of Cellular Biomolecules

Endogenous biomolecules in cells are the basis of all life activities.Directly visualizing the structural characteristics and dynamic behaviors of cellular biomolecules is signiffcant for understanding the molecular mechanisms in various biological processes.Singlemolecule localization microscopy(SMLM)can circumvent the optical diffraction limit,achieving analysis of the ffne structures and biological processes in living cells with nanoscale resolution.However,the large size of traditional imaging probes prevents SMLM from accurately locating ffne structures and densely distributed biomolecules within cells.In recent years,nucleic acid probes have emerged as potential tools to replace conventional SMLM probes by virtue of their small size and high speciffcity.In addition,due to their programmability,nucleic acid probes with different conformations can be constructed via sequence design,further extending the application of SMLM in bioanalysis.Here,we discuss the design concepts of different conformational nucleic acid probes for SMLM and summarize the application of SMLM based on nucleic acid probes in the ffeld of biomolecules.Furthermore,we provide a summary and future perspectives of the nucleic acid probe-based SMLM technology,aiming to provide guidance for the acquisition of nanoscale information about cellular biological processes.