Conjugated polymers (CPs) are referred to a kind of fluorescent polymer materials with delocalized n-conjugated backbones. For the last decades, cationic CPs (CCPs) have been widely used in biosensor, imaging and ...Conjugated polymers (CPs) are referred to a kind of fluorescent polymer materials with delocalized n-conjugated backbones. For the last decades, cationic CPs (CCPs) have been widely used in biosensor, imaging and biomedical fields due to their good photophysical properties and solubility in water medium resulting from side chain modification with ionized moieties. In this mini-review, we mainly introduced the applications of CCPs in detection and inactivation of pathogen with typical examples, and also briefly discussed the relevant mechanisms. We hold the expectation that this mini-review can offer researchers a general reference and inspire them to construct new systems with high performances of pathogen detection and antimicrobial activity.展开更多
Infectious disease outbreaks have seriously endangered global health owing to the scarcity of testing materials and techniques.Diversified materials and methods should be urgently developed for rapid detection and dis...Infectious disease outbreaks have seriously endangered global health owing to the scarcity of testing materials and techniques.Diversified materials and methods should be urgently developed for rapid detection and discrimination of pathogenic microorganisms.Conjugated polymer(CP)materials are macromolecular compounds comprising numerous covalently bonded luminescent units.They have excellent light-harvesting and optical signal amplification capabilities owing to the transmission of excitation energy along their backbone.In recent years,CP materials have aroused research enthusiasm in the biosensors field because of their outstanding optoelectronic properties.This brief manuscript provides an overall review of recent progress achieved in CP-based systems for pathogen sensing.展开更多
基金supported by the National Natural Science Foundation of China (21473221, 21473220)
文摘Conjugated polymers (CPs) are referred to a kind of fluorescent polymer materials with delocalized n-conjugated backbones. For the last decades, cationic CPs (CCPs) have been widely used in biosensor, imaging and biomedical fields due to their good photophysical properties and solubility in water medium resulting from side chain modification with ionized moieties. In this mini-review, we mainly introduced the applications of CCPs in detection and inactivation of pathogen with typical examples, and also briefly discussed the relevant mechanisms. We hold the expectation that this mini-review can offer researchers a general reference and inspire them to construct new systems with high performances of pathogen detection and antimicrobial activity.
基金supported by the Natural Science Foundation of China(No.21704005)Fundamental Research Funds for the Cen-tral Universities(No.300102310106).
文摘Infectious disease outbreaks have seriously endangered global health owing to the scarcity of testing materials and techniques.Diversified materials and methods should be urgently developed for rapid detection and discrimination of pathogenic microorganisms.Conjugated polymer(CP)materials are macromolecular compounds comprising numerous covalently bonded luminescent units.They have excellent light-harvesting and optical signal amplification capabilities owing to the transmission of excitation energy along their backbone.In recent years,CP materials have aroused research enthusiasm in the biosensors field because of their outstanding optoelectronic properties.This brief manuscript provides an overall review of recent progress achieved in CP-based systems for pathogen sensing.