Balanced acupuncture, a single-acupoint balance therapy, regulates the balance of the cerebral center, and is characterized by exerting quick effects and a short treatment course. A total of 20 low-back and leg pain p...Balanced acupuncture, a single-acupoint balance therapy, regulates the balance of the cerebral center, and is characterized by exerting quick effects and a short treatment course. A total of 20 low-back and leg pain patients with lumbar disc herniation were treated with balanced acupuncture or body acupuncture. Central mechanisms of vaded acupunctures were compared using resting-state functional MRI. Patients from both groups received functional MRI before and after acupuncture. Functional connectivity in brain regions that were strongly associated with the bilatera amygdala was analyzed utilizing AFNI software. Visual analogue scale scores were greater in the balanced acupuncture group compared with the body acupuncture group. Function of the endogenous pain regulation network was enhanced in patients in the balanced acupuncture group, but was not changed in the body acupuncture group. This result indicates that the analgesic effects of body acupuncture do not work through the central nervous system. These data suggest that balanced acupuncture exerts analgesic effects on low-back and leg pain patients with lumbar disc herniation by regulating the function of the endogenous pain regulation network.展开更多
Nutritional management and suitable weight control during pregnancy are very important. However, in clinical practice, it is difficult to determine in detail precisely what pregnant women are eating. We investigated n...Nutritional management and suitable weight control during pregnancy are very important. However, in clinical practice, it is difficult to determine in detail precisely what pregnant women are eating. We investigated nutritional balance and nutritional requirements in pregnant women and their relationship to the course of pregnancy. A Food Frequency Questionnaire Based on Food Groups (FFQg) was distributed to 223 women at 12 weeks gestation attending one obstetrics clinic. We observed the women’s statuses until delivery and obtained information on pregnancy, delivery, and newborn from their medical records. One hundred and forty-seven (65.9%) of the subjects had problem-free pregnancies. Only 2 (0.9%) subjects developed pregnancy-induced hypertension syndrome. Participants were classified by pre-pregnancy BMI (body mass index;kg/m2) as follows: 44 (19.7%) were underweight (BMI the three groups. However, the underweight group consumed significantly more fat than the normal group and gained significantly more weight before delivery than the others. Blood pressure was significantly higher in the overweight group than in the other groups at some points of gestation, although it remained within the normal range. Fat intake overall was more than the recommended value, especially in the underweight group. The relationship between course of pregnancy and nutritional intake was unclear. However, pre-pregnancy BMI may influence the course of pregnancy in terms of infant weight, gestational weight gain, and blood pressure.展开更多
The body channel based wireless power transfer(BC-WPT)method utilizes the human body as the medium to transfer power for bioelectronics,which can achieve a lower transmission loss due to its higher conductivity.Howeve...The body channel based wireless power transfer(BC-WPT)method utilizes the human body as the medium to transfer power for bioelectronics,which can achieve a lower transmission loss due to its higher conductivity.However,except for the channel length,different on-body loca-tions of the transmitter and receiver also influence the power supply performance.This paper fo-cuses on the wrist-to-forehead path to show the potential of BC-WPT for the brain bioelectronics such as the brain computer interface device.The channel characteristics from 10 MHz to 60 MHz are measured by a vector network analyzer(VNA)and a prototype BC-WPT system with differ-ent copper electrodes and the lowest power loss locates between-22 dB and-33 dB.Furthermore,the minimum path loss limit is simulated in Advanced Design System(ADS)software and the low-est optimum path loss can reach nearly-13 dB.Finally,a rectifier circuit is also built at the receiv-er side to harvest d.c.voltage.The results show that the open-circuit voltage(OCV)can reach 1.75 V with the transmitter of 50Ωoutput impedance supplying 5V_(pp)sine voltage at 60 MHz when adopt-ing 1 cm-diameter circular electrodes.展开更多
Outcome-based contract( OBC) is a kind of contracting mechanism,which allows the customer to pay only when the firm has delivered outcomes,rather than activities and tasks involved. To achieve the higher demand of the...Outcome-based contract( OBC) is a kind of contracting mechanism,which allows the customer to pay only when the firm has delivered outcomes,rather than activities and tasks involved. To achieve the higher demand of the delivering outcome of the contract,the evaluation of contractor's performance was focused on. A reasonable and objective contractor performance evaluation system is constructed by considering various uncertainties. The set pair theory is used to analyze the four-element connection of quality of service contractors. It aims to provide a theoretical basis for the decisionmaker to make confirmation of the equipment contractor who has a better performance and development trend.展开更多
Digital factory technology is an advanced manufacturing technology served as to establish a bridge between the process of product development and manufacturing.In terms of application for digital factory technology in...Digital factory technology is an advanced manufacturing technology served as to establish a bridge between the process of product development and manufacturing.In terms of application for digital factory technology in machining,especially in machining of a complicated part such as a cylinder body part,a concept of digital process planning and its framework are proposed.Its components including machining domain knowledge model,machining knowledge base,machining resource base and process planning system are studied.A machining knowledge model in tree form and an object-driven knowledge reasoning mechanism are used for machining knowledge base.The process planning system is a user interface that leads a planner to finish the planning process.A case about a cylinder head part is given to demonstrate how the platform works.The framework of digital process planning is the foundation of some intelligent CAPP systems and helps to production line planning.展开更多
To efficiently develop deep shale gas in southern Sichuan Basin,under the guidance of“extreme utilization”theory,a basic idea and solutions for deep shale gas development are put forward and applied in practice.In v...To efficiently develop deep shale gas in southern Sichuan Basin,under the guidance of“extreme utilization”theory,a basic idea and solutions for deep shale gas development are put forward and applied in practice.In view of multiple influencing factors of shale gas development,low single-well production and marginal profit of wells in this region,the basic idea is to establish“transparent geological body”of the block in concern,evaluate the factors affecting shale gas development through integrated geological-engineering research and optimize the shale gas development of wells in their whole life cycle to balance the relationship between production objectives and development costs.The solutions are as follows:(1)calculate the gold target index and pinpoint the location of horizontal well drilling target,and shale reservoirs are depicted accurately by geophysical and other means to build underground transparent geological body;(2)optimize the drilling and completion process,improve the adaptability of key tools by cooling,reducing density and optimizing the performance of drilling fluid,the“man-made gas reservoir”is built by comprehensively considering the characteristics of in-situ stress and fractures after the development well is drilled;(3)through efficient management,establishment of learning curve and optimization of drainage and production regime,the development quality and efficiency of the well are improved across its whole life cycle,to fulfil“extreme utilization”development of shale gas.The practice shows that the estimated ultimate recovery of single wells in southern Sichuan Basin increase by 10%-20%than last year.展开更多
In the process of unconventional natural gas development practice,the"extreme utilization"concept that focuses on"continuously breaking through the limit of development technology"is gradually form...In the process of unconventional natural gas development practice,the"extreme utilization"concept that focuses on"continuously breaking through the limit of development technology"is gradually formed,and supports the scale benefit exploration of unconventional gas in China.On this basis,the development theory of"extreme utilization"is proposed,its theoretical connotation together with development technologies of unconventional natural gas are clarified.The theoretical connotation is that,aiming at"extreme gas reservoirs","extreme techniques"are utilized to build subsurface connected bodies,expand the discharge area,and enlarge the production range,to obtain the maximum single-well production,extreme recovery,and eventually achieve the"extreme effect"of production.The series of development technologies include micro/nano-scale reservoir evaluation,"sweet spot"prediction,unconventional percolation theory and production capacity evaluation,optimization of grid well pattern,optimal-fast drilling and volume fracturing,and working regulation optimization and"integrated"organizing system.The"extreme utilization"development theory has been successfully applied in the development of unconventional gas reservoirs such as Sulige tight gas,South Sichuan shale gas,and Qinshui coalbed methane.Such practices demonstrate that,the"extreme utilization"development theory has effectively promoted the development of unconventional gas industry in China,and can provide theoretical guidance for effective development of other potential unconventional and difficult-to-recovery resources.展开更多
The identification of tissue origin of body fluid can provide clues and evidence for criminal case investigations.To establish an efficient method for identifying body fluid in forensic cases,eight novel body fluid-sp...The identification of tissue origin of body fluid can provide clues and evidence for criminal case investigations.To establish an efficient method for identifying body fluid in forensic cases,eight novel body fluid-specific DNA methylation markers were selected in this study,and a multiplex single base extension reaction(SNaPshot)system for these markers was constructed for the identification of five common body fluids(venous blood,saliva,menstrual blood,vaginal fluid,and semen).The results indicated that the in-house system showed good species specificity,sensitivity,and ability to identify mixed biological samples.At the same time,an artificial body fluid prediction model and two machine learning prediction models based on the support vector machine(SVM)and random forest(RF)algorithms were constructed using previous research data,and these models were validated using the detection data obtained in this study(n=95).The accuracy of the prediction model based on experience was 95.79%;the prediction accuracy of the SVM prediction model was 100.00%for four kinds of body fluids except saliva(96.84%);and the prediction accuracy of the RF prediction model was 100.00%for all five kinds of body fluids.In conclusion,the in-house SNaPshot system and RF prediction model could achieve accurate tissue origin identification of body fluids.展开更多
基金funded by the Scientific Research Innovation Program regarding Traditional Chinese Medicine of Guangzhou University of Chinese Medicine (Central mechanism of balanced acupuncture for lumbar disc herniationusing functional MRI), No. 09CX068
文摘Balanced acupuncture, a single-acupoint balance therapy, regulates the balance of the cerebral center, and is characterized by exerting quick effects and a short treatment course. A total of 20 low-back and leg pain patients with lumbar disc herniation were treated with balanced acupuncture or body acupuncture. Central mechanisms of vaded acupunctures were compared using resting-state functional MRI. Patients from both groups received functional MRI before and after acupuncture. Functional connectivity in brain regions that were strongly associated with the bilatera amygdala was analyzed utilizing AFNI software. Visual analogue scale scores were greater in the balanced acupuncture group compared with the body acupuncture group. Function of the endogenous pain regulation network was enhanced in patients in the balanced acupuncture group, but was not changed in the body acupuncture group. This result indicates that the analgesic effects of body acupuncture do not work through the central nervous system. These data suggest that balanced acupuncture exerts analgesic effects on low-back and leg pain patients with lumbar disc herniation by regulating the function of the endogenous pain regulation network.
文摘Nutritional management and suitable weight control during pregnancy are very important. However, in clinical practice, it is difficult to determine in detail precisely what pregnant women are eating. We investigated nutritional balance and nutritional requirements in pregnant women and their relationship to the course of pregnancy. A Food Frequency Questionnaire Based on Food Groups (FFQg) was distributed to 223 women at 12 weeks gestation attending one obstetrics clinic. We observed the women’s statuses until delivery and obtained information on pregnancy, delivery, and newborn from their medical records. One hundred and forty-seven (65.9%) of the subjects had problem-free pregnancies. Only 2 (0.9%) subjects developed pregnancy-induced hypertension syndrome. Participants were classified by pre-pregnancy BMI (body mass index;kg/m2) as follows: 44 (19.7%) were underweight (BMI the three groups. However, the underweight group consumed significantly more fat than the normal group and gained significantly more weight before delivery than the others. Blood pressure was significantly higher in the overweight group than in the other groups at some points of gestation, although it remained within the normal range. Fat intake overall was more than the recommended value, especially in the underweight group. The relationship between course of pregnancy and nutritional intake was unclear. However, pre-pregnancy BMI may influence the course of pregnancy in terms of infant weight, gestational weight gain, and blood pressure.
文摘The body channel based wireless power transfer(BC-WPT)method utilizes the human body as the medium to transfer power for bioelectronics,which can achieve a lower transmission loss due to its higher conductivity.However,except for the channel length,different on-body loca-tions of the transmitter and receiver also influence the power supply performance.This paper fo-cuses on the wrist-to-forehead path to show the potential of BC-WPT for the brain bioelectronics such as the brain computer interface device.The channel characteristics from 10 MHz to 60 MHz are measured by a vector network analyzer(VNA)and a prototype BC-WPT system with differ-ent copper electrodes and the lowest power loss locates between-22 dB and-33 dB.Furthermore,the minimum path loss limit is simulated in Advanced Design System(ADS)software and the low-est optimum path loss can reach nearly-13 dB.Finally,a rectifier circuit is also built at the receiv-er side to harvest d.c.voltage.The results show that the open-circuit voltage(OCV)can reach 1.75 V with the transmitter of 50Ωoutput impedance supplying 5V_(pp)sine voltage at 60 MHz when adopt-ing 1 cm-diameter circular electrodes.
文摘Outcome-based contract( OBC) is a kind of contracting mechanism,which allows the customer to pay only when the firm has delivered outcomes,rather than activities and tasks involved. To achieve the higher demand of the delivering outcome of the contract,the evaluation of contractor's performance was focused on. A reasonable and objective contractor performance evaluation system is constructed by considering various uncertainties. The set pair theory is used to analyze the four-element connection of quality of service contractors. It aims to provide a theoretical basis for the decisionmaker to make confirmation of the equipment contractor who has a better performance and development trend.
文摘Digital factory technology is an advanced manufacturing technology served as to establish a bridge between the process of product development and manufacturing.In terms of application for digital factory technology in machining,especially in machining of a complicated part such as a cylinder body part,a concept of digital process planning and its framework are proposed.Its components including machining domain knowledge model,machining knowledge base,machining resource base and process planning system are studied.A machining knowledge model in tree form and an object-driven knowledge reasoning mechanism are used for machining knowledge base.The process planning system is a user interface that leads a planner to finish the planning process.A case about a cylinder head part is given to demonstrate how the platform works.The framework of digital process planning is the foundation of some intelligent CAPP systems and helps to production line planning.
基金Suppoted by the Forward-Looking Basic Project of China National Petroleum Corporation(2021DJ19).
文摘To efficiently develop deep shale gas in southern Sichuan Basin,under the guidance of“extreme utilization”theory,a basic idea and solutions for deep shale gas development are put forward and applied in practice.In view of multiple influencing factors of shale gas development,low single-well production and marginal profit of wells in this region,the basic idea is to establish“transparent geological body”of the block in concern,evaluate the factors affecting shale gas development through integrated geological-engineering research and optimize the shale gas development of wells in their whole life cycle to balance the relationship between production objectives and development costs.The solutions are as follows:(1)calculate the gold target index and pinpoint the location of horizontal well drilling target,and shale reservoirs are depicted accurately by geophysical and other means to build underground transparent geological body;(2)optimize the drilling and completion process,improve the adaptability of key tools by cooling,reducing density and optimizing the performance of drilling fluid,the“man-made gas reservoir”is built by comprehensively considering the characteristics of in-situ stress and fractures after the development well is drilled;(3)through efficient management,establishment of learning curve and optimization of drainage and production regime,the development quality and efficiency of the well are improved across its whole life cycle,to fulfil“extreme utilization”development of shale gas.The practice shows that the estimated ultimate recovery of single wells in southern Sichuan Basin increase by 10%-20%than last year.
基金Supported by the China National Science and Technology Major Project(2017ZX05035,2016ZX05037)。
文摘In the process of unconventional natural gas development practice,the"extreme utilization"concept that focuses on"continuously breaking through the limit of development technology"is gradually formed,and supports the scale benefit exploration of unconventional gas in China.On this basis,the development theory of"extreme utilization"is proposed,its theoretical connotation together with development technologies of unconventional natural gas are clarified.The theoretical connotation is that,aiming at"extreme gas reservoirs","extreme techniques"are utilized to build subsurface connected bodies,expand the discharge area,and enlarge the production range,to obtain the maximum single-well production,extreme recovery,and eventually achieve the"extreme effect"of production.The series of development technologies include micro/nano-scale reservoir evaluation,"sweet spot"prediction,unconventional percolation theory and production capacity evaluation,optimization of grid well pattern,optimal-fast drilling and volume fracturing,and working regulation optimization and"integrated"organizing system.The"extreme utilization"development theory has been successfully applied in the development of unconventional gas reservoirs such as Sulige tight gas,South Sichuan shale gas,and Qinshui coalbed methane.Such practices demonstrate that,the"extreme utilization"development theory has effectively promoted the development of unconventional gas industry in China,and can provide theoretical guidance for effective development of other potential unconventional and difficult-to-recovery resources.
基金supported by the National Natural Science Foundation of China(Nos.81930055 and 81772031).
文摘The identification of tissue origin of body fluid can provide clues and evidence for criminal case investigations.To establish an efficient method for identifying body fluid in forensic cases,eight novel body fluid-specific DNA methylation markers were selected in this study,and a multiplex single base extension reaction(SNaPshot)system for these markers was constructed for the identification of five common body fluids(venous blood,saliva,menstrual blood,vaginal fluid,and semen).The results indicated that the in-house system showed good species specificity,sensitivity,and ability to identify mixed biological samples.At the same time,an artificial body fluid prediction model and two machine learning prediction models based on the support vector machine(SVM)and random forest(RF)algorithms were constructed using previous research data,and these models were validated using the detection data obtained in this study(n=95).The accuracy of the prediction model based on experience was 95.79%;the prediction accuracy of the SVM prediction model was 100.00%for four kinds of body fluids except saliva(96.84%);and the prediction accuracy of the RF prediction model was 100.00%for all five kinds of body fluids.In conclusion,the in-house SNaPshot system and RF prediction model could achieve accurate tissue origin identification of body fluids.