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Omni-Channel Retailing and Firm Performance from a Customer Lifetime Value Perspective
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作者 Liu Xiangdong Mi Zhuang He Mingqin 《China Economist》 2024年第3期89-103,共15页
In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to... In the digital era,retailers are keen to find out whether omni-channel retailing helps improve long-term firm performance.In this paper,we employ machine learning techniques on a large consumption data set in order to measure customer lifetime value(CLV)as the basis for determining long-term firm performance,and we provide an empirical analysis of the relationship between omni-channel retailing and CLV.The results suggest that omni-channel retailing may effectively enhance CLV.Further analysis reveals that this process is influenced by heterogeneous consumer requirements and that significant differences exist in the extent to which the omni-channel transition may influence CLV depending on consumer preferences for diversity of commodities,sensitivity to the cost of contract performance,and sensitivity to warehousing costs.Hence,retailers should provide consumers with a complete portfolio of goods and services based on target consumers’heterogeneous requirements in order to increase omni-channel efficiency. 展开更多
关键词 Omni-channel retailing customer lifetime value machine learning heterogeneous consumer requirements
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Construction of Value Models of Consumer Creation for Agricultural Products Based on the Analytic Hierarchy Process(AHP) 被引量:2
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作者 杨庆先 汤自英 《Agricultural Science & Technology》 CAS 2010年第4期180-183,共4页
With the increased competition of modern economy and globalization,consumer creation which based on the analysis of consumer behavior was more and more attentioned and respected by business.Based on the meaning and ch... With the increased competition of modern economy and globalization,consumer creation which based on the analysis of consumer behavior was more and more attentioned and respected by business.Based on the meaning and characteristics of agricultural product consumer creation,index system of value model of agricultural product consumer creation was put forward through analytical hierarchy process(AHP).The weights of the indicators and related indicators of impact on the value were analyzed,and value models of agricultural product consumer creation were constructed to provide ideas for development of agricultural product consumer market and research of consumer value.Consumer creation was constructed to provide ideas for development of agricultural product consumer market and research of consumer value. 展开更多
关键词 Agricultural Products consumer Creation Analytic Hierarchy Process(AHP) value Model
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Motives Underlying Organic Food Consumption in Turkey: Impact of Health, Environment, and Consumer Values on Purchase Intentions 被引量:1
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《Economics World》 2017年第4期333-345,共13页
Raising ecological awareness and health concerns create question marks about healthiness and sustainability of conventional foods in customers' minds. Due to augmented mass media coverage of environmental problems, h... Raising ecological awareness and health concerns create question marks about healthiness and sustainability of conventional foods in customers' minds. Due to augmented mass media coverage of environmental problems, health concerns related to consumption of genetically modified food and/or chemical contaminants in food, and consumers' increasing interest in healthy nutrition and environmental protection, there is a growing interest for organic foods in all over the world. Growing interest for organic foods, and increasing production and demand in organic food market has made organic food consumption a significant topic of research. Although organic food market and demand for organic foods have also been growing in Turkey, literature regarding organic food consumption is not very extensive. Therefore, this study aims to understand the underlying motives for organic food consumption in Turkey, and to explore the factors affecting Turkish consumers' attitudes towards organic foods and the behavioral intention of Turkish consumers to purchase organic food by the help of the theory of reasoned action (TRA). The results of 622 successful surveys used for this empirical research indicate that Turkish consumers' attitudes towards organic foods are determined by perception of organic foods, consumer values, and price perception, while their purchase intention is determined by health consciousness, perception of organic foods, consumer values, price perception, and environmental concerns. 展开更多
关键词 organic foods consumer behavior theory of reasoned action food purchase motivations food purchaseintentions TURKEY health consciousness environmental concern consumer values
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Overview of the Consumer Behavior Study in the Markets of Food Products(1998-2018),Based on the Author’s Interpretation of the Consumer's Requirements in the System of Values that Influence on the Consumer Market Behavior
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作者 Galina V.Astratova 《Proceedings of Business and Economic Studies》 2018年第4期1-28,共28页
The purpose of this study was to review the results of a 20-year study in the author’s interpretation of the needs for food products and the value system that determines the market behavior of consumers in the food m... The purpose of this study was to review the results of a 20-year study in the author’s interpretation of the needs for food products and the value system that determines the market behavior of consumers in the food markets.The scientific novelty of the research is the following results:a)The author’s interpretation of the needs for food products,as consisting of three components:(1)The actual need for food(physiological need);(2)the need for emotions obtained from eating(psychological need);and(3)the need for market products that can meet the physiological needs of emotional expectations and social needs(socio-psychological and economic need);b)Interdisciplinary approach to the study of consumer behavior that led to the author’s interpretation of the value of the research methods outlined in the works of J.N.Sheth et al.,extended and supplemented in the study of Galina V.Astratova(1998);c)Identification of the fact that the importance of components in the system of values,according to the results of research,is different for different food products.This allows simulating more clearly the behavior of the consumer in the development of a marketing-mix and developing a marketing strategy based on targeting. 展开更多
关键词 needs wants demand consumer consumer behavior values system of values MARKETING FOOD MARKETING MARKETING research MARKETING research tools marketing-mix FOOD PRODUCTs MARKETs FOOD PRODUCTs organic FOOD PRODUCTs
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Research on the O2O model of consumer behavior under the perspectives of culture and values
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《International Journal of Technology Management》 2016年第8期58-60,共3页
In this paper, we conduct research on the O2O model of the consumer behavior under the perspectives of culture and values.Electronic commerce is striding forward O2O will follow the pace of history. O2O mode obvious a... In this paper, we conduct research on the O2O model of the consumer behavior under the perspectives of culture and values.Electronic commerce is striding forward O2O will follow the pace of history. O2O mode obvious advantages, is helpful to promote thedevelopment of the electricity industry. O2O model development has quietly changed our life, is not only the change of consumption patterns,but also poses challenges to the traditional industry. O2O core is through the sale, to provide information and services, to push offl ine storesales promotion information to Internet users, and take them to the entity shop to consumer goods or enjoy. This paper integrates the consumerbehavior to propose the new O2O model which is innovative. 展开更多
关键词 O2O model consumer behavior culture and values perspective.
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Pearl S. Buck’s Values of “Cultural Convergence” and Their Application
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作者 WANG Yan ZHU Ze-yuan SHI Hui-ge 《Cultural and Religious Studies》 2023年第1期9-18,共10页
The typical features of internal and external integration of cultures as revealed by the conception of“cultural convergence”provide a new perspective on the study of cultural exchanges and mutual learning.In the con... The typical features of internal and external integration of cultures as revealed by the conception of“cultural convergence”provide a new perspective on the study of cultural exchanges and mutual learning.In the context of“a global community of shared future for humankind”,this paper adopts the novel idea of“cultural convergence”to probe the growth of Pearl S.Buck’s cultural values and the specific contents and representation of Pearl S.Buck’s conception of“cultural convergence”,highlighting the application of Pearl S.Buck’s values to cultural education,growth and success,family education,cultural exchanges,humanistic practices,etc.Feasible suggestions and countermeasures are put forward to better promote the cultural exchanges and mutual learning as well as the convergence of different cultures. 展开更多
关键词 Pearl s.Buck values of“cultural convergence” applied research
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Emotional Value Care to Promote Emotional Communication Between Teachers and Students Under the New Era of Education Mode
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作者 Yongdong Xiao 《Journal of Contemporary Educational Research》 2023年第1期7-12,共6页
With the development of the times and the progress of the society,the ancient education mode can no longer meet the requirements of the times.The concept of educating people must keep pace with the times.The way teach... With the development of the times and the progress of the society,the ancient education mode can no longer meet the requirements of the times.The concept of educating people must keep pace with the times.The way teachers and students get along is no longer like in ancient times,where teachers teach students to listen.In the new era,it is necessary to build a new model of interaction between teachers and students.If educators pay attention and come to understand students’psychology,listen to students’aspirations,tend to students’emotions,grow in love for education,and treat students from their hearts,they would be able to win the favor of students.Paying attention to students’emotional value can promote emotional communication between teachers and students.It is possible to adapt to the requirements of the new era for the construction of morality and ethics among teachers by caring for students’emotional value. 展开更多
关键词 Teacher’s morality Teacher’s style Emotional value Emotional communication
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Prognostic Value of Semi-Quantitative 18F-FDG PET/CT Parameters in Hodgkin’s Lymphoma
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作者 Yong Zhou Congyang Hu +7 位作者 Yue Li Xiting Xia Jun Lei Jingyi Chen Hua Xu Mei He Hongyun Jian Shuping You 《Proceedings of Anticancer Research》 2023年第6期108-115,共8页
Objective:To assess the prognostic value of maximum standardized uptake value(SUVmax),metabolic tumor volume(MTV),and total lesion glycolysis(TLG)determined by 18F-fluorodeoxyglucose positron emission tomography-compu... Objective:To assess the prognostic value of maximum standardized uptake value(SUVmax),metabolic tumor volume(MTV),and total lesion glycolysis(TLG)determined by 18F-fluorodeoxyglucose positron emission tomography-computed tomography(18F-FDG PET/CT)imaging in Hodgkin’s lymphoma patients.Methods:A total of 148 Hodgkin’s lymphoma patients diagnosed with lymph node biopsy from October 2014 to October 2015 were retrospectively analyzed followed by categorizing into good(125 cases)and poor(23 cases)prognosis groups.The chi-squared test was used to analyze the clinicopathological characteristics of Hodgkin’s lymphoma patients with the semi-quantitative 18F-FDG PET/CT parameters;the Spearman method was used to analyze the correlation between the semi-quantitative parameters and clinicopathological features of Hodgkin’s lymphoma;receiver operating characteristic curve was used to analyze the predictive value of the semi-quantitative parameters for poor prognosis of Hodgkin’s lymphoma patients.Results:Mean SUVmax,MTV,and TLG of the 148 cases of Hodgkin’s lymphoma were 7.26±2.38,12.46±3.14 cm3,and 76.83±18.56 g,respectively.Significant variations in the Ann Arbor stage and clinical classification were observed with different levels of semi-quantitative parameters(P<0.05).The semi-quantitative parameters were not correlated with age and gender(P>0.05)but positively correlated with Ann Arbor stage and clinical classification(P<0.05).These parameters in the poor prognosis group were higher than those in the good prognosis group(P<0.05).The area under the curve(AUC)of SUVmax,MTV,and TLG in predicting the poor prognosis group was 0.881,0.875,and 0.838,with cut-off values of 7.264,12.898 cm3,and 74.580g,as well as specificity of 88.8%,84.0%,and 78.4%,and sensitivity of 87.0%,87.0%,and 78.3%,respectively;the AUC of the combined prediction was 0.986,with a specificity of 97.6%and sensitivity of 86.3%.Conclusion:The semi-quantitative 18F-FDG PET/CT parameters provide valuable insights for Hodgkin’s lymphoma prognosis assessment. 展开更多
关键词 Hodgkin’s lymphoma 18F-fluorodeoxyglucose positron emission tomography-computed tomography Maximum standardized uptake value Metabolic tumor volume Total lesion glycolysis PROGNOsIs
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Investigation on the Consumption Values of Hong Kong People on Tie Products 被引量:1
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作者 Sarah Mei-yi Leung Alice Wai-ching Chu Kit-lun Yick 《Journal of Donghua University(English Edition)》 EI CAS 2004年第2期52-59,共8页
This study aims at investigating the consumption values of Hong Kong people on necktie. Based on the Sheth-Newman-Gross Model of consumption values on consumers’ choice decision as conceptual framework, results from ... This study aims at investigating the consumption values of Hong Kong people on necktie. Based on the Sheth-Newman-Gross Model of consumption values on consumers’ choice decision as conceptual framework, results from the focus group interview, a questionnaire was designed and adopted for conducting the survey. Data collected from 245 respondents were analysed using the Factor Analysis to review the important elements of consumers’ decision of purchasing tie products. Implications on the results on the Functional value were reviewed and discussed in details. Interesting elements such as fabric hand-feel were also identified as influential associated in Hong Kong consumers’ selection of necktie. Since, both fibre content and fabric handle were also found as major selection criteria for fabric materials, the study was focused on the analysis of functional value of the product and further extended to study the handle preference for Hong Kong customers, in which a subjective handle assessment of a wide range of tie fabrics being newly developed and introduced in the market was conducted and objective fabric physical and mechanical properties were measured. Important fabric handle attributes that influence the consumers’ preference on tie fabrics were identified and their objective translation by fabric physical and mechanical properties were also obtained. The investigation provides decision support to necktie manufacturers and retailers through scientific and quantitative recommendations for product development of tie products and material selection. 展开更多
关键词 Necktie Hand-feel consumption values and consumer Behaviour
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SPD助力手术室高值医用耗材精细化管理 被引量:1
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作者 于卫红 贾佳 《中国医院建筑与装备》 2024年第1期61-64,共4页
对生产厂家、供应商、物流公司、设备物资科及手术室进行规范化管理,利用SPD医用耗材管理系统及智能感知柜管理系统,改变原有手术室高值医用耗材逆向物流的模式,建立院内手术室高值医用耗材的正向物流管理模式及追溯机制,以降低临床医... 对生产厂家、供应商、物流公司、设备物资科及手术室进行规范化管理,利用SPD医用耗材管理系统及智能感知柜管理系统,改变原有手术室高值医用耗材逆向物流的模式,建立院内手术室高值医用耗材的正向物流管理模式及追溯机制,以降低临床医用耗材管理工作强度,实现高值医用耗材可视化管理和精细化管理,为医院进行科学合理的宏观调控提供可靠准确的信息,在保证高值医用耗材使用快捷的同时,最大限度地保证手术室高值医用耗材在使用中的安全性及可追溯性。 展开更多
关键词 手术室 高值医用耗材 医疗器械唯一标识 医用耗材管理系统
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2022年四川芦山M_(S)6.1地震前应力状态研究
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作者 张致伟 曾宪伟 +4 位作者 王迪 路茜 王玮铭 杨鹏 龙锋 《地震研究》 CSCD 北大核心 2024年第4期483-492,共10页
为研究2022年6月1日四川芦山M_(S)6.1地震的孕育和发生过程,采用CAP方法反演了2013年芦山M_(S)7.0主震及M_(S)≥5.0余震的震源机制解,并基于应力张量方差与b值时空分布特征,探讨了芦山M_(S)6.1地震的力学机制和震源区的应力状态。结果表... 为研究2022年6月1日四川芦山M_(S)6.1地震的孕育和发生过程,采用CAP方法反演了2013年芦山M_(S)7.0主震及M_(S)≥5.0余震的震源机制解,并基于应力张量方差与b值时空分布特征,探讨了芦山M_(S)6.1地震的力学机制和震源区的应力状态。结果表明:2022年芦山M_(S)6.1地震震源机制表现出与2013年芦山M_(S)7.0主震和5级余震相似的逆冲型破裂特征,压应力轴方位与龙门山断裂带南段区域应力场一致。2013年芦山M_(S)7.0地震后震中及附近的应力张量方差和b值长期处于低值状态,2022年芦山M_(S)6.1地震前震中及附近出现了应力张量方差和b值的低值异常,表明芦山余震区处于较高的应力水平。分析认为:巴颜喀拉块体持续东向运动受到华南块体的阻挡,震中所在区域长期受挤压逆冲作用,从而使芦山余震区长期处于应力积累的状态,芦山M_(S)6.1地震也是在这种动力学背景下发生的。 展开更多
关键词 芦山M_(s)6.1地震 芦山M_(s)7.0地震 震源机制解 应力张量方差 B值 应力状态
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梅毒螺旋体抗体最佳S/CO截断值在梅毒筛查中的应用价值
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作者 王靖 李小全 +4 位作者 刘敏 杨志立 徐植 赵雅淳 王丽 《实用中西医结合临床》 2024年第10期1-5,共5页
目的 以梅毒螺旋体凝集试验(TPPA)作为确认试验,确立酶联免疫吸附试验(ELISA)法S/CO值与梅毒阳性最佳截断值,减少不必要的TPPA确认重复。方法 选取2022年10月至2023年10月在医院进行梅毒螺旋体(TP)抗体检测的血清标本22 500例,以ELISA... 目的 以梅毒螺旋体凝集试验(TPPA)作为确认试验,确立酶联免疫吸附试验(ELISA)法S/CO值与梅毒阳性最佳截断值,减少不必要的TPPA确认重复。方法 选取2022年10月至2023年10月在医院进行梅毒螺旋体(TP)抗体检测的血清标本22 500例,以ELISA法为梅毒初次筛查试验,采用TPPA和甲苯胺红不加热血清试验(TRUST)对所有反应结果进行复核和确认。分析376例有反应性标本中的S/CO值与TPPA的关系,使用受试者操作特征曲线(ROC)确定ELISA法S/CO值与TPPA阳性最佳截断值。根据S/CO最佳截断值,比较梅毒不同反式筛查策略需要TPPA确认的标本数量。结果 当S/CO≥6.6时,TPPA与ELISA结果一致,特异性和阳性预测值均为100.00%,S/CO=6.6时为最佳截断值;使用欧洲疾病预防与控制中心(ECDC)策略时,376例筛查反应性样本(100.00%,376/376)需TPPA确认;使用美国疾病控制与预防中心(CDC)策略时,TPPA还需确认217例(57.71%,217/376);本研究只有122例(32.45%,122/376)需进行TPPA确认。结论 采用ELISA法梅毒反式筛查策略不受TRUST结果影响,当S/CO≥6.6时不需要进行TPPA确认,与ECDC和CDC反式策略相比,本研究有67.55%的筛查反应样本不必进行TPPA确认,经济且节约时间和人力。 展开更多
关键词 梅毒 s/CO值 最佳截断值 TPPA
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基于S-O-R模型的视觉营销对消费者购买意愿的影响研究——以红色文创网店为例 被引量:1
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作者 魏加兴 张婷婷 《市场周刊》 2024年第1期76-80,共5页
为提高红色文创网店的点击转化率,文章从消费者视角出发,研究影响消费者购买意愿的视觉因素。基于S-O-R模型理论,构建红色文创网店视觉营销对消费者购买意愿因素的理论模型。利用S-O-R模型分析了红色文创网店视觉营销中的商品形象、界... 为提高红色文创网店的点击转化率,文章从消费者视角出发,研究影响消费者购买意愿的视觉因素。基于S-O-R模型理论,构建红色文创网店视觉营销对消费者购买意愿因素的理论模型。利用S-O-R模型分析了红色文创网店视觉营销中的商品形象、界面形象以及品牌视觉形象对顾客感知价值及顾客购买意向的影响。通过设计量表和调查问卷进行实证研究,并结合结构方程模型加以论证,得出品牌视觉形象和界面形象是影响消费者购买意愿的关键因素,为设计师和红色文创品牌进行网店设计提供了一定的理论参考和建议。 展开更多
关键词 s-O-R模型 消费者购买意愿 红色文创产品 视觉营销
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S-100β CysC和NF-κB对急性缺血性脑卒中患者静脉溶栓后出血转化的预测价值
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作者 李鹤 李樱 李磊 《中国实用神经疾病杂志》 2024年第4期415-419,共5页
目的 探讨急性缺血性脑卒中(AIS)外周血中S-100β、CysC和NF-κB水平对静脉溶栓后出血转化的影响及预测价值。方法 收集2019-03—2022-03接受溶栓治疗的AIS患者140例,根据溶栓后24 h是否发生出血转化(HT)将患者分为非HT组(n=112)和HT组(... 目的 探讨急性缺血性脑卒中(AIS)外周血中S-100β、CysC和NF-κB水平对静脉溶栓后出血转化的影响及预测价值。方法 收集2019-03—2022-03接受溶栓治疗的AIS患者140例,根据溶栓后24 h是否发生出血转化(HT)将患者分为非HT组(n=112)和HT组(n=28)。比较2组一般临床资料,采用多因Logistic回归分析影响HT发生的危险因素,受试者工作特征(ROC)曲线评估S-100β、CysC和NF-κB预测HT发生的价值。结果 HT组与非HT组相比,患者年龄、发病至溶栓时间、房颤、TOAST分型、C反应蛋白、凝血酶原时间、S-100β、CysC、NF-κB、白质高信号和脑微出血等均有统计学差异(P<0.05)。Logistic多因素回归分析显示,房颤、S-100β、CysC和NF-κB为影响HT发生的危险因素。S-100β、CysC和NF-κB预测AIS患者静脉溶栓后出血转化的曲线下面积分别为0.915(0.902~0.923)、0.874(0.856~0.882)和0.789(0.771~0.796),均具有一定的预测价值。结论 S-100β、CysC和NF-κB为AIS患者静脉溶栓后HT发生的危险因素,对HT发生具有一定的预测价值。 展开更多
关键词 急性缺血性脑卒中 静脉溶栓 出血转化 中枢神经特异蛋白 胱抑素C 核因子ΚB 外周血 危险因素 预测价值
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EXISTENCE OF SOLUTION FOR A BOUNDARY VALUE PROBLEM OF FRACTIONAL ORDER 被引量:27
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作者 张淑琴 《Acta Mathematica Scientia》 SCIE CSCD 2006年第2期220-228,共9页
This article considers the existence of solution for a boundary value problem of fractional order, involving Caputo's derivative{C0D^δtu(t)=g(t,u(t)),0〈t〈1,1〈δ〈2,u(0)α≠0,u(1)=β≠0.
关键词 Boundary value Laplace transform Mittage-Leffler function fractionalderivative Caputo's derivative fixed point CONE
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Measuring Recreational Value of World Heritage Sites Based on Contingent Valuation Method:A Case Study of Jiuzhaigou 被引量:8
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作者 DONG Xuewang ZHANG Jie +2 位作者 ZHI Ruizhi ZHONG Shi'en LI Min 《Chinese Geographical Science》 SCIE CSCD 2011年第1期119-128,共10页
World heritage possesses various kinds of use value and non-use value. Measuring the recreational value of world heritage sites is a key issue in the heritage tourism. This paper employs Contingent Valuation Method (C... World heritage possesses various kinds of use value and non-use value. Measuring the recreational value of world heritage sites is a key issue in the heritage tourism. This paper employs Contingent Valuation Method (CVM), which is an evaluation instrument on the basis of tourists′ attitude and preference, to measure the recreational value of Jiuzhaigou, one of the World Natural Heritage sites in China, and analyzes the biases in the survey. The results show that: 1) In 2009, Jiuzhaigou′s recreational value was 3.46×108 yuan (RMB), and the per capita Willingness to Pay (WTP) was 137.31 yuan by CVM. Compared with the results of other methods, this result is significantly low. 2) Among the factors that influence Jiuzhaigou tourists′ WTP, psychological perception factors have the greatest effect while demographic and socio-economic characteristics have a small effect on WTP. 3) The virtuality in CVM creates biases both from CVM itself and in the procedures that CVM was implemented. The former includes hypothetical bias, information bias, protest response bias, and strategic bias; and the latter includes the questionnaire design, population and sample definition, sampling and data processing. The paper analyses those biases and illustrates their potential in-fluences on the accuracy of CVM measurement. 4) Although there are various defects in CVM measurement, it is still an effective valuation method. 展开更多
关键词 Contingent valuation Method (CVM) Willingness to Pay (WTP) tourist's attitude tourist's preference world heritage recreational value BIAs Jiuzhalgou
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EXISTENCE OF SOLUTION FOR BOUNDARY VALUE PROBLEM OF NONLINEAR FRACTIONAL DIFFERENTIAL EQUATION 被引量:10
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作者 Su Xinwei Liu Landong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2007年第3期291-298,共8页
This paper is concerned with the boundary value problem of a nonlinear fractional differential equation. By means of Schauder fixed-point theorem, an existence result of solution is obtained.
关键词 fractional differential equation boundary value problem Caputo's fractional derivative schauder fixed-point theorem.
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Optimal b value of diffusion-weighted imaging on a 3.0T magnetic resonance scanner in Crohn's disease 被引量:4
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作者 Qi Feng Yun-Qi Yan +2 位作者 Jiong Zhu Jin-Lu Tong Jian-Rong Xu 《World Journal of Gastroenterology》 SCIE CAS 2014年第35期12621-12627,共7页
AIM: To determine the optimal b value of diffusion-weighted imaging for detecting active inflammation in Crohn&#x02019;s disease.
关键词 Crohn’ s disease Diffusion-weighted imaging b value Magnetic resonance image 3.0 Tesla
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Assessment of self- and cross-absorbed SAF values for HDRK-man using GEANT4 code: internal photon and electron emitters 被引量:1
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作者 Maroua Bhar Omrane Kadri Kais Manai 《Nuclear Science and Techniques》 SCIE CAS CSCD 2019年第10期40-47,共8页
The ultimate need to account for the partial amount of energy deposited in target tissue/organ resulting from internal inhalation,ingestion,and injection intakes of radionuclides,defined by the Medical Internal Radiat... The ultimate need to account for the partial amount of energy deposited in target tissue/organ resulting from internal inhalation,ingestion,and injection intakes of radionuclides,defined by the Medical Internal Radiation Dosimetry committee as the specific absorbed fraction(SAF),has become obvious.In this study,we assessed the SAF values for self-and cross-absorption,which were calculated for a uniform distribution of monoenergetic photon and electron emitters with energies ranging from 15 keV to 3 MeV.The voxelized human phantom‘‘High-Definition Reference Korean-man’’(HDRK-man),which was implemented using the Monte Carlo simulation code GEANT4(version 10.1),was used for several combinations of target–source organs.The results were compared to those of the International Commission on Radiological Protection Reference(ICRP133)and Zubal phantoms.It was found that the SAF values of the three models have a similar trend.However,the SAF values for the HDRK-man phantom were higher than those of the other two models,with a relatively good agreement with those for the ICRP133 phantom(differences of 13.9±2.8 and 12.1±3.2 for photon and electron emitters,respectively).To analyze the differences in SAF values,we calculated the chord length distributions(CLDs)for selected target–source combinations.The parameters of organ mass(or volume)and CLDs,in addition to the adopted computational procedures,mainly cause such discrepancies.For realistic radionuclide emission spectra,an overall overestimation was observed when computing the S values for three radiopharmaceuticals studied(I-131,In-111,and Lu-177)and for liver–spleen intra-and inter-organ absorption when compared with published data.The new arrangement of S and SAF values is expected to add value for multidisciplinary research and clinical communities. 展开更多
关键词 GEANT4 Monte Carlo simulation INTERNAL DOsIMETRY HDRK-man s and sAF values
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血清CysC、α-Syn联合MRI对帕金森病病情评估及诊断的意义 被引量:1
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作者 吕晨光 路凯 +1 位作者 王丽 李振玲 《国际检验医学杂志》 CAS 2024年第5期554-558,共5页
目的 探讨血清胱抑素C(CysC)、α-突触核蛋白(α-Syn)联合磁共振成像(MRI)对帕金森病(PD)病情评估及诊断的意义。方法 将2019年4月至2021年4月于河北省沧州中西医结合医院(下称该院)治疗的PD患者87例纳入研究作为PD组。根据Hoehn-Yahr(H... 目的 探讨血清胱抑素C(CysC)、α-突触核蛋白(α-Syn)联合磁共振成像(MRI)对帕金森病(PD)病情评估及诊断的意义。方法 将2019年4月至2021年4月于河北省沧州中西医结合医院(下称该院)治疗的PD患者87例纳入研究作为PD组。根据Hoehn-Yahr(H-Y)分期,将PD患者分为Ⅰ~Ⅱ期13例,Ⅲ~Ⅳ期45例,Ⅴ期29例。另外,选取同期于该院进行体检的健康志愿者87例作为对照组。比较各组血清CysC、α-Syn水平,分析血清CysC、α-Syn联合MRI对PD的诊断效能。结果 PD组血清CysC、α-Syn水平均高于对照组,差异有统计学意义(P<0.05);血清CysC、α-Syn水平随着H-Y分期递增升高(P<0.05)。PD组MRI各相位值与对照组比较,黑质致密带、苍白球、壳核、尾状核相位值均降低(P<0.05);不同H-Y分期的PD患者黑质致密带、苍白球、壳核相位值比较,差异均有统计学意义(P<0.05)。CysC、α-Syn单独诊断PD的AUC分别为0.786、0.767,灵敏度分别为58.62%、64.37%,特异度分别为88.51%、87.36%;与MRI、血清CysC、α-Syn单独诊断相比,三项联合诊断PD的灵敏度和准确度较高同,差异有统计学意义(P<0.05)。结论 血清CysC、α-Syn联合MRI对PD诊断效能较高,能为评估PD病情严重程度和早期诊断提供依据。 展开更多
关键词 胱抑素C Α-突触核蛋白 磁共振成像 帕金森病 诊断价值 病情评估
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