Purpose: To investigate the efficacy and complications of continuous wear of etafilcon A for therapeutic use. Materials and Methods: The subjects were 228 eyes of 219 outpatients prescribed contact lens (CL) for one w...Purpose: To investigate the efficacy and complications of continuous wear of etafilcon A for therapeutic use. Materials and Methods: The subjects were 228 eyes of 219 outpatients prescribed contact lens (CL) for one week of continuous therapeutic wear during 10 years. The reason for prescription of CLs, the primary disease, the duration of CL wear and the complications were assessed retrospectively. Results: The predominant reason for prescription of CLs was relief of pain or a foreign-body sensation (62.3%) and protection of the corneal epithelium (20.6%). The primary disease was post-penetrating keratoplasty (36.8%), followed by corneal epithelial erosion (14.5%), post-lamellar keratoplasty (14.0%) and bullous keratopathy (12.2%). The average duration of wearing single lens was 6.5 ± 3.2 days. The average duration of wearing CLs in total was 9.2 ± 10.7 months. The most frequent problem associated with continuous wear of CLs was their dropping out of CLs (12.3%). The complications associated with CLs included conjunctivitis with papillary hyperplasia, corneal erosion and superficial punctate keratitis, but corneal ulcer and corneal infiltrates were not found. Conclusion: Serious complications were not shown changing the lenses every week to keep to the prescribed time limit for continuous therapeutic wear, even if corneal epithelial barrier function is impaired.展开更多
AIM: To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS: A prospective, double-masked study was conducted on 42 eyes of 21 patients ...AIM: To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS: A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was less than -1.50D. Patients were randomly assigned to wear Galyfilcon A (Lens A) bandage contact lens in one eye and Balafilcon A (Lens B) in the fellow eye after the surgery. The responses to a subjective questionnaire on comfort of wearing, corneal epithelial status, conjunctival hyperemia, limbal neovascularization, lens fitting and contact lens debris were assessed 1 and 5 days postoperatively. Corneal endothelium was assessed before and 5 days after the surgery upon bandage lens removal. RESULTS: There was no difference between the two groups in terms of conjunctival hyperemia, limbal neovascularization, contact lens fitting, corneal epithelial status, corneal endothelium cell density (CD) and endothelium cell size (CS) at any postoperative visit. Complaints of discomfort, including foreign body sensation, pain and intolerance were statistically more among Lens B wearers at any postoperative visit (P < 0.05). Lens B appeared to attract much more debris than Lens A at the 5-day post-operative follow-up visit (P < 0.01). CONCLUSION: The two types of silicon hydrogel lenses investigated in this study demonstrated similar clinical performance in terms of corneal responses and lens fitting. However, Lens A showed a better performance in terms of comfort of wearing and deposit resistance.展开更多
目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,...目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,对照组仅给予人工泪液治疗。连续治疗1个月后比较两组自觉症状评分、泪液分泌试验(SⅠt,SⅡt)情况、泪膜破裂时间(Break Up Time,BUT)以及泪液蕨样变试验(Tear Ferning Test,TFT)情况。结果治疗后,两组患者的自觉症状评分均下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组SⅠt、SⅡt以及BUT指标水平均改善,且观察组改善效果更优,差异有统计学意义(P<0.05);观察组TFT指标检测水平优于对照组,差异有统计学意义(P<0.05)。结论治疗性绷带式角膜接触镜在重症泪眼蒸发过强型干眼症患者的治疗中效果确切,能够显著改善其自觉症状评分以及SⅠt、BUT和TFT等指标。展开更多
文摘Purpose: To investigate the efficacy and complications of continuous wear of etafilcon A for therapeutic use. Materials and Methods: The subjects were 228 eyes of 219 outpatients prescribed contact lens (CL) for one week of continuous therapeutic wear during 10 years. The reason for prescription of CLs, the primary disease, the duration of CL wear and the complications were assessed retrospectively. Results: The predominant reason for prescription of CLs was relief of pain or a foreign-body sensation (62.3%) and protection of the corneal epithelium (20.6%). The primary disease was post-penetrating keratoplasty (36.8%), followed by corneal epithelial erosion (14.5%), post-lamellar keratoplasty (14.0%) and bullous keratopathy (12.2%). The average duration of wearing single lens was 6.5 ± 3.2 days. The average duration of wearing CLs in total was 9.2 ± 10.7 months. The most frequent problem associated with continuous wear of CLs was their dropping out of CLs (12.3%). The complications associated with CLs included conjunctivitis with papillary hyperplasia, corneal erosion and superficial punctate keratitis, but corneal ulcer and corneal infiltrates were not found. Conclusion: Serious complications were not shown changing the lenses every week to keep to the prescribed time limit for continuous therapeutic wear, even if corneal epithelial barrier function is impaired.
文摘AIM: To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS: A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was less than -1.50D. Patients were randomly assigned to wear Galyfilcon A (Lens A) bandage contact lens in one eye and Balafilcon A (Lens B) in the fellow eye after the surgery. The responses to a subjective questionnaire on comfort of wearing, corneal epithelial status, conjunctival hyperemia, limbal neovascularization, lens fitting and contact lens debris were assessed 1 and 5 days postoperatively. Corneal endothelium was assessed before and 5 days after the surgery upon bandage lens removal. RESULTS: There was no difference between the two groups in terms of conjunctival hyperemia, limbal neovascularization, contact lens fitting, corneal epithelial status, corneal endothelium cell density (CD) and endothelium cell size (CS) at any postoperative visit. Complaints of discomfort, including foreign body sensation, pain and intolerance were statistically more among Lens B wearers at any postoperative visit (P < 0.05). Lens B appeared to attract much more debris than Lens A at the 5-day post-operative follow-up visit (P < 0.01). CONCLUSION: The two types of silicon hydrogel lenses investigated in this study demonstrated similar clinical performance in terms of corneal responses and lens fitting. However, Lens A showed a better performance in terms of comfort of wearing and deposit resistance.
文摘目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,对照组仅给予人工泪液治疗。连续治疗1个月后比较两组自觉症状评分、泪液分泌试验(SⅠt,SⅡt)情况、泪膜破裂时间(Break Up Time,BUT)以及泪液蕨样变试验(Tear Ferning Test,TFT)情况。结果治疗后,两组患者的自觉症状评分均下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组SⅠt、SⅡt以及BUT指标水平均改善,且观察组改善效果更优,差异有统计学意义(P<0.05);观察组TFT指标检测水平优于对照组,差异有统计学意义(P<0.05)。结论治疗性绷带式角膜接触镜在重症泪眼蒸发过强型干眼症患者的治疗中效果确切,能够显著改善其自觉症状评分以及SⅠt、BUT和TFT等指标。
