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STUDY ON MECHANICAL INTERACTIONS BETWEEN SINGLE CARDIAC MYOCYTE AND ELASTIC SUBSTRATE 被引量:3
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作者 Jianyong Huang Tao Zhu +3 位作者 Lei Qin Xiaoling Peng Chunyang Xiong Jing Fang 《Acta Mechanica Solida Sinica》 SCIE EI 2009年第6期563-570,共8页
Quantitative investigation on mechanical characteristics of cardiac myocytes has important physiological significance. Based on elastic substrate technique, this paper develops a set of algorithms for high-efficiency ... Quantitative investigation on mechanical characteristics of cardiac myocytes has important physiological significance. Based on elastic substrate technique, this paper develops a set of algorithms for high-efficiency cellular traction recovery. By applying a gradient-based digital image correlation method to track randomly distributed fluorescence microbeads on the deformed substrate induced by single cardiac myocyte, high-resolution substrate displacement field can readily be obtained. By using a numerical algorithm based on the integral Boussinesq solution, cell-substrate tractions are reconstructed in a stable and reliable manner. Finally, spatiotemporal dynamics of a single cardiac myocyte is investigated as it adheres to a polyacrylamide elastic substrate. 展开更多
关键词 cardiac myocyte elastic substrate deformation digital image correlation traction recovery contraction work intensity
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