Synthesis of 9-Halo Prostaglandin Derivatives and Their Effect on Uterus Contraction

Four 9-halo prostaglandin derivatives were designed and synthesized. Their structures were confirmed by IR,~1HNMR, MS, etc. The effect on uterus contraction of ratswas studied in vitro. It was found that compound g-Br seemed to be the most sensitive andγ-Cl somewhat less, while a-Cl and a-Br had almost no action as compared with oxytocin(1 IU/ml).

CEOs’Diverse Career Experiences and the Effectiveness of Compensation Contracts:Evidence from Compensation Stickiness

CEO compensation stickiness represents an important indicator to measure the effectiveness of compensation contracts.This study uses CEO career experience data and compensation stickiness data from Shanghai and Shenzhen A-share listed companies from 2015 to 2020 to investigate the compensation contracts’effectiveness of CEOs with diverse career experiences.The findings are as follows:1)Compensation stickiness is more pronounced for CEOs with diverse career experiences.According to the mechanism test,these CEOs with diverse career experiences can obtain compensation incentives by reducing corporate uncertainty perception and improving total factor productivity.This approach leads to increased compensation stickiness and the effectiveness of compensation contracts.CEOs with diverse career experiences may receive excess compensation by raising agency costs,which intensifies compensation stickiness and weakens the effectiveness of compensation contracts.2)Compensation stickiness of CEOs with diverse career experiences is more significant in companies with lower investor protection,which brings about less effective compensation contracts.In contrast,in companies with higher diversification,the compensation stickiness of CEOs with diverse career experiences is more significant,which delivers more effective compensation contracts.The conclusions deepen the research of CEO compensation contracts and provide a helpful reference for CEO compensation management practices.

Electronic and Magnetic Properties of Small Iridium Clusters

The electronic and magnetic properties of small IrN clusters (N=5, 6, 9, 13, and 19 ) are studied by using the discrete-variational local-spin-density-functional method. The equilibrium bond length in the chosen geometry for IrN clusters are determined and show bond contraction compared with the bulk interatomic spacing. The clusters with magnetic ground state have ferromagnetic interaction and their average magnetic moment per atom has a complex size dependence. At last, the reactivity of IrN clusters toward H2, N2 and CO molecules is predicted.

EXPERIMENT STUDY ON THE EFFECT OF SHENG-MAI INJECTION ON THE CONTRACTIVITY OF DIAPHRAGM AND ITS MECHANISM

In this study the effect of Sheng-ai Injection i.e. Red Ginseng-Ophiopogon Root Injection (one kind of traditional Chinese medicines) on the contractivity of diaphragm was observed. The results confirmed that Sheng-ai Injection increased Pdi of the fatigued diaphragm in rabbits and reduced the time needed for the recovery of Pdi of fatigued diaphragm to the normal value. These results suggest that Sheng-Mai Injection can increase the contractive force and promote the recovery of the fatigued diaphragm. The effect of Sheng-ai Injection on the contractivity of the isolated diaphragmatic bundle of rats was also observed and the results confirmed that Sheng-ai Injection increased the diaphragmatic contractive force directly. This effect of increasing the contractive force of diaphragm was attenuated by adding calcium channel blocker isoptin and disappeared when there was no calcium in the extracellular fluid. It is deduced, therefore, that the mechanism of the effect of Sheng-mai Injection is related to the increased influx of calcium from extracellular fluid into the cells.