The value of combined application of both ECG gated cine MRA and 3D CEMRA in the detection of large intracranial aneurysms was evaluated and the findings were compared with those of conventional MRA and DSA. Twenty ...The value of combined application of both ECG gated cine MRA and 3D CEMRA in the detection of large intracranial aneurysms was evaluated and the findings were compared with those of conventional MRA and DSA. Twenty four patients with 26 large intracranial aneurysms underwent MRI and DSA. All these aneurysms, diameter from 15 to 39 mm, were located at internal cerebral artery ( n= 12), vertebral artery ( n= 3), basilar artery ( n= 4), anterior cerebral artery ( n= 2), middle cerebral artery ( n= 2), anterior communicate artery ( n= 2) and posterior communicate artery ( n= 1). Thirteen cases of hematoma or cavernoma were studied as control group. All patients were examined on GE 1.5T MR system. ECG gated cine MRA was performed with 2D multi phase fast gradient recalled echo sequence in a single section. All the images were analyzed with signal intensity VS time curve for differentiating intraaneurysmal blood flow from static tissue. The results were analzsed by statistic ' t ' test. 3D CEMRA was performed with spoiled gradient recalled echo and one dose of Gd DTPA. All data was processed with multi plannar reformat (MPR) and tomography for the demonstration of aneurysms in detail. All 26 aneurysms were demonstrated successfully by combined application of both cine MRA and 3D CEMRA. Compared to DSA and conventional 3D MOTSA, its sensitivity and specificity figures were both 100 %. Cine MRA could differentiate the blood flow from the static tissue. The intensity VS time curves of intraaneurysmal blood flow offered fluctuating form and average signal change between systole and diastole period was about 89.8±37.4; However, under the control group, intraaneurysmal thrombus or cerebral hemorrhage or cavernomas had no significant signal change and the curves offered steady form with the average signal change being about 8.2±6.3. There was statistically significant difference between the intraaneurysmal blood flow and static tissue ( P =0.025, <0.05). 3D CEMRA was very useful in demonstrating the aneurysmal size, intraaneurysmal thrombus formation, neck and the detailed relationship of the aneurysm to the surrounding structures. It was concluded that the combined application of both cine MRA and 3D CEMRA might be a valuable clinical tool for the detection of large intracranial aneurysms.展开更多
文摘The value of combined application of both ECG gated cine MRA and 3D CEMRA in the detection of large intracranial aneurysms was evaluated and the findings were compared with those of conventional MRA and DSA. Twenty four patients with 26 large intracranial aneurysms underwent MRI and DSA. All these aneurysms, diameter from 15 to 39 mm, were located at internal cerebral artery ( n= 12), vertebral artery ( n= 3), basilar artery ( n= 4), anterior cerebral artery ( n= 2), middle cerebral artery ( n= 2), anterior communicate artery ( n= 2) and posterior communicate artery ( n= 1). Thirteen cases of hematoma or cavernoma were studied as control group. All patients were examined on GE 1.5T MR system. ECG gated cine MRA was performed with 2D multi phase fast gradient recalled echo sequence in a single section. All the images were analyzed with signal intensity VS time curve for differentiating intraaneurysmal blood flow from static tissue. The results were analzsed by statistic ' t ' test. 3D CEMRA was performed with spoiled gradient recalled echo and one dose of Gd DTPA. All data was processed with multi plannar reformat (MPR) and tomography for the demonstration of aneurysms in detail. All 26 aneurysms were demonstrated successfully by combined application of both cine MRA and 3D CEMRA. Compared to DSA and conventional 3D MOTSA, its sensitivity and specificity figures were both 100 %. Cine MRA could differentiate the blood flow from the static tissue. The intensity VS time curves of intraaneurysmal blood flow offered fluctuating form and average signal change between systole and diastole period was about 89.8±37.4; However, under the control group, intraaneurysmal thrombus or cerebral hemorrhage or cavernomas had no significant signal change and the curves offered steady form with the average signal change being about 8.2±6.3. There was statistically significant difference between the intraaneurysmal blood flow and static tissue ( P =0.025, <0.05). 3D CEMRA was very useful in demonstrating the aneurysmal size, intraaneurysmal thrombus formation, neck and the detailed relationship of the aneurysm to the surrounding structures. It was concluded that the combined application of both cine MRA and 3D CEMRA might be a valuable clinical tool for the detection of large intracranial aneurysms.
