Multidisciplinary collaborative simulation （MCS） is an important area of research in the domain of multidisciplinary design optimization （MDO）.Although previous research for MCS has to some extent addressed some i...Multidisciplinary collaborative simulation （MCS） is an important area of research in the domain of multidisciplinary design optimization （MDO）.Although previous research for MCS has to some extent addressed some issues like using of multiple tools,integration stability,control of step size,data synchronization,etc,further work is still necessary to study how to achieve improved precision.A theoretical model is formulated to describe and analyze the integration process of MCS.A basic algorithm with equal major steps is proposed based on the model,along with two methods of implementation for the model,namely the serial method and the parallel method.A further algorithm based on convergent integration step is proposed,which has a more flexible strategy for run-time integration.The influence of interpolation techniques on simulation performance is studied as well.Simulations of the performance of various algorithms with different interpolation techniques are performed for both a simple numerical example and a complex mechatronic product.The novel algorithm based on convergent integration step,when used with a high-order interpolation technique,has better performance in terms of precision and efficiency.The innovation of this paper is mainly on the validation of high precision of the proposed convergent integration step algorithm.展开更多
Chlorospermines A and B are biologically interesting acridone natural products and recently isolated from Glycosmis chlorosperma.We report here a convergent approach to construct the tetracyclic core of the natural pr...Chlorospermines A and B are biologically interesting acridone natural products and recently isolated from Glycosmis chlorosperma.We report here a convergent approach to construct the tetracyclic core of the natural products.The two fragments are assembled together through Sonogashira coupling,and a cis-triene intermediate was prepared by using hydrosilylation/desilylation.A 6p-electrocyclization/aromatization sequence served as the key step of the synthesis,which formed the tetrasubstituted arene motif in one pot.展开更多
基金supported by National Natural Science Foundation of China (Grant No. 61074110)National Defense Pre-Research Foundation of China (Grant No. B0420060524)
文摘Multidisciplinary collaborative simulation （MCS） is an important area of research in the domain of multidisciplinary design optimization （MDO）.Although previous research for MCS has to some extent addressed some issues like using of multiple tools,integration stability,control of step size,data synchronization,etc,further work is still necessary to study how to achieve improved precision.A theoretical model is formulated to describe and analyze the integration process of MCS.A basic algorithm with equal major steps is proposed based on the model,along with two methods of implementation for the model,namely the serial method and the parallel method.A further algorithm based on convergent integration step is proposed,which has a more flexible strategy for run-time integration.The influence of interpolation techniques on simulation performance is studied as well.Simulations of the performance of various algorithms with different interpolation techniques are performed for both a simple numerical example and a complex mechatronic product.The novel algorithm based on convergent integration step,when used with a high-order interpolation technique,has better performance in terms of precision and efficiency.The innovation of this paper is mainly on the validation of high precision of the proposed convergent integration step algorithm.
基金Ministry of Science & Technology (No.2013CB836900)National Natural Science Foundation of China (Nos.21290180,21172235 and 21222202)China Postdoctoral Science Foundation (No.2014M561537,M.Y.)
文摘Chlorospermines A and B are biologically interesting acridone natural products and recently isolated from Glycosmis chlorosperma.We report here a convergent approach to construct the tetracyclic core of the natural products.The two fragments are assembled together through Sonogashira coupling,and a cis-triene intermediate was prepared by using hydrosilylation/desilylation.A 6p-electrocyclization/aromatization sequence served as the key step of the synthesis,which formed the tetrasubstituted arene motif in one pot.
