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Two-Mode Converters at 1.3μm Based on Multimode Interference Couplers on InP Substrates 被引量:1
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作者 郭菲 陆丹 +3 位作者 张瑞康 王会涛 王圩 吉晨 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第2期39-42,共4页
Two-mode converters at 1.3μm, aiming at applications in mode-division multiplexing in Ethernet systems, are proposed and experimentally demonstrated. Based on multimode interference couplers, the two-mode converters ... Two-mode converters at 1.3μm, aiming at applications in mode-division multiplexing in Ethernet systems, are proposed and experimentally demonstrated. Based on multimode interference couplers, the two-mode converters with 50% and 66% mode conversion efficiencies are designed and fabricated on InP substrates. AIode conver- sion from the fundamental mode (TEo) to the first order mode (TE1) is successfully demonstrated within the wavelength range of 1280-1320nm. The 1.3-μm mode converters should be important devices in mode-division multiplexing systems in Ethernet systems. 展开更多
关键词 MODE INP Two-Mode converters at 1.3 m based on Multimode Interference Couplers on InP Substrates of in TE on
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Hydrodynamic Simulation of Wave Energy Converter Using Particle-Based Computational Fluid Dynamics 被引量:1
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作者 Yodchai Tiaple 《Journal of Marine Science and Application》 CSCD 2019年第1期48-53,共6页
Wave energy from the ocean is currently a very popular renewable energy, and its development has primarily focused on the shape of the wave energy converter(WEC) used to efficiently convert wave energy into electrical... Wave energy from the ocean is currently a very popular renewable energy, and its development has primarily focused on the shape of the wave energy converter(WEC) used to efficiently convert wave energy into electrical energy. However, the free surface ocean wave problem is very complex and the parameters affecting WEC behavior are difficult to understand. In this paper, based on the Lattice-Boltzmann method, we present particle-based CFD simulation results for the pivoted-type WEC that exhibits both vertical and horizontal motions. In this method, the computation domain need not be a mesh and complex geometry is not a limiting factor. Using a free-surface turbulence model, we simulated the fluid-structure interaction. We detail our simulation results, which show good agreement with those in the literature. 展开更多
关键词 Wave energy converter Pivoted BUOY LATTICE-BOLTZMANN Particle-based CFD
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A distributed VSG control method for a battery energy storage system with a cascaded H-bridge in a grid-connected mode 被引量:6
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作者 Yichi Cai Donglian Qi 《Global Energy Interconnection》 EI CAS CSCD 2022年第4期343-352,共10页
With the high penetration of renewable energy,new challenges,such as power fluctuation suppression and inertial support capability,have arisen in the power sector.Battery energy storage systems play an essential role ... With the high penetration of renewable energy,new challenges,such as power fluctuation suppression and inertial support capability,have arisen in the power sector.Battery energy storage systems play an essential role in renewable energy integration.In this paper,a distributed virtual synchronous generator(VSG)control method for a battery energy storage system(BESS)with a cascaded H-bridge converter in a grid-connected mode is proposed.The VSG is developed without communication dependence,and state-of-charge(SOC)balancing control is achieved using the distributed average algorithm.Owing to the low varying speed of SOC,the bandwidth of the distributed communication networks is extremely slow,which decreases the cost.Therefore,the proposed method can simultaneously provide inertial support and accurate SOC balancing.The stability is also proved using root locus analysis.Finally,simulations under different conditions are carried out to verify the effectiveness of the proposed method. 展开更多
关键词 VSG Cascaded h-bridge converters Battery energy storage system Renewable energy integration
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Damping controller design based on FO-PID-EMA in VSC HVDC system to improve stability of hybrid power system 被引量:2
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作者 Nima SHAFAGHATIAN Arvin KIANI +2 位作者 Naser TAHERI Zahra RAHIMKHANI Seyyed Saeed MASOUMI 《Journal of Central South University》 SCIE EI CAS CSCD 2020年第2期403-417,共15页
Wind energy sources have different structures and functions from conventional power plants in the power system.These resources can affect the exchange of active and reactive power of the network.Therefore,power system... Wind energy sources have different structures and functions from conventional power plants in the power system.These resources can affect the exchange of active and reactive power of the network.Therefore,power system stability will be affected by the performance of wind power plants,especially in the event of a fault.In this paper,the improvement of the dynamic stability in power system equipped by wind farm is examined through the supplementary controller design in the high voltage direct current(HVDC)based on voltage source converter(VSC)transmission system.In this regard,impacts of the VSC HVDC system and wind farm on the improvement of system stability are considered.Also,an algorithm based on controllability(observability)concept is proposed to select most appropriate and effective coupling between inputs-outputs(IO)signals of system in different work conditions.The selected coupling is used to apply damping controller signal.Finally,a fractional order PID controller(FO-PID)based on exchange market algorithm(EMA)is designed as damping controller.The analysis of the results shows that the wind farm does not directly contribute to the improvement of the dynamic stability of power system.However,it can increase the controllability of the oscillatory mode and improve the performance of the supplementary controller. 展开更多
关键词 hybrid power system high voltage direct current based on voltage source converter(VSC HVDC) fractional order PID(FO-PID)damping controller exchange market algorithm
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DC Traction Power Supply System Based on Modular Multilevel Converter Suitable for Energy Feeding and De-icing 被引量:1
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作者 Lingxi Hou Shuqing Zhang +4 位作者 Yingdong Wei Xiaoqian Li Qirong Jiang Mingrui Li Weirui Li 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2024年第2期649-659,共11页
A novel DC traction power supply system suitable for energy feeding and de-icing is proposed in this paper for an urban rail transit catenary on the basis of the full bridge submodule (FBSM) modular multilevel convert... A novel DC traction power supply system suitable for energy feeding and de-icing is proposed in this paper for an urban rail transit catenary on the basis of the full bridge submodule (FBSM) modular multilevel converter (MMC). The FBSM-MMC is a novel type of voltage source converter (VSC) and can directly control the output DC voltage and conduct bipolar currents, thus flexibly controlling the power flow of the urban rail transit catenary. The proposed topology can overcome the inherent disadvantages of the output voltage drop in the diode rectifier units, increase the power supply distance and reduce the number of traction substations. The flexible DC technology can coordinate multiple FBSM-MMCs in a wide area and jointly complete the bidirectional control of catenary power flow during the operation of the electric locomotive, so as to realize the local consumption and optimal utilization of the recovered braking energy of the train. In addition, the FBSM-MMCs can also adjust the output current when the locomotive is out of service to prevent the catenary from icing in winter. The working modes of the proposed topology are illustrated in detail and the control strategy is specially designed for normal locomotive operations and catenary de-icing. Simulation cases conducted by PSCAD/EMTDC validate the proposed topology and its control strategy. 展开更多
关键词 DC traction power supply system de-icing for catenary energy feeding modular multilevel converter based on full-bridge submodules(FBSM-MMC) urban rail transit
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Hybrid Optimized PI Controller Design for Grid Tied PV Based Electric Vehicle
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作者 J.Aran Glenn Srinivasan Alavandar 《Intelligent Automation & Soft Computing》 SCIE 2023年第5期1523-1545,共23页
Nowadays,researchers are becoming increasingly concerned about developing a highly efficient emission free transportation and energy generation system for addressing the pressing issue of environmental crisis in the fo... Nowadays,researchers are becoming increasingly concerned about developing a highly efficient emission free transportation and energy generation system for addressing the pressing issue of environmental crisis in the form of pollution and climate change.The introduction of Electric Vehicles(EVs)solves the challenge of emission-free transportation while the necessity for decarbonized energy production is fulfilled by the installation and expansion of solar-powered Photovoltaic(PV)systems.Hence,this paper focuses on designing an effective PV based EV charging system that aids in stepping towards the achievement of a pollution free future.For overcoming the inherent intermittency associated with PV,a novel DC-DC converter is designed by integrating both Trans Z-source con-verter and Luo converter,which offers remarkable benefits of high conversion range,lesser voltage stress and excellent efficiency.A novel robust Lion Grey Wolf Optimized Proportional Integral(LGWO-PI)controller is designed for sig-nificantly strengthening the operation of the integrated converter in terms of peak overshoot,Total Harmonic Distortion(THD)and settling time.A 3’Voltage Source Inverter(VSI)is employed to convert the stable DC output from the PV sys-tem to AC,which is then used for driving the Brushless Direct Current Motor(BLDC)motor of EV.The speed of the BLDC is regulated using a PI controller.The BLDC motor gets the power supply from the grid during the unavailability of PV based power supply.The grid is integrated with the designed EV charging system through a 1’VSI and the process of grid voltage synchronization is carried out with the application of PI controller.The simulation for evaluating the operation of the presented EV charging system is done using MATLAB and the attained out-comes have validated that this introduced methodology delivers enhanced perfor-mance with optimal efficiency of 97.6%and lesser THD of 2.1%. 展开更多
关键词 PV system trans Z-source based luo converter LGWO-PI controller BLDC motor PI controller single phase VSI three phase VSI
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Research on System Architecture of Novel Universal Integrated Control and Protection Platform for Converter Stations 被引量:1
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作者 HU Jing ZHAO Chengyong +3 位作者 ZHAO Guoliang ZHOU Fei WANG Jing CAI Xinhong 《中国电机工程学报》 EI CSCD 北大核心 2012年第22期I0018-I0018,共1页
关键词 保护系统 集成控制 高压直流输电工程 换流站 架构 平台 通用 HVDC
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Capacitor Pattern H-Bridge Multilevel Inverter (CPHMLI) Using Phase Diposition Pulse Width Modulation for Grid Applications
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作者 M. S. Saravanan R. Jeyabharath 《Circuits and Systems》 2016年第10期3310-3319,共10页
This work presents an implementation of an innovative single phase multilevel inverter using capacitors with reduced switches. The proposed Capacitor pattern H-bridge Multilevel Inverter (CPHMLI) topology consists of ... This work presents an implementation of an innovative single phase multilevel inverter using capacitors with reduced switches. The proposed Capacitor pattern H-bridge Multilevel Inverter (CPHMLI) topology consists of a proper number of Capacitor connected with switches and power sources. The advanced switching control supplied by Pulse Width Modulation (PDPWM) to attain mixed staircase switching state. The charging and discharging mode are achieved by calculating the voltage error at the load. Furthermore, to accomplish the higher voltage levels at the output with less number of semiconductors switches and simple commutation designed using CPHMLI topology. To prove the performance and effectiveness of the proposed approach, a set of experiments performed under various load conditions using MATLAB tool. 展开更多
关键词 Switched Capacitor Multilevel Inverter Phase Diposition Pulse Width Modulation Capacitor Pattern based Multilevel Inverter Total Harmonic Distortion Cascaded h-bridge 17-Level Inverter
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Application of GaN in Hard-switching Converters:Challenges and Potential Solutions
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作者 Bo LIU Zhe-yu ZHANG +1 位作者 Edward Jones Fei(Fred) WANG 《电力电子技术》 CSCD 北大核心 2017年第9期3-11,共9页
This paper overviews the benefits,challenges,research trends and potential solutions on the design and application of gallium nitride(GaN) technology in hard-switching power electronic converters from the device level... This paper overviews the benefits,challenges,research trends and potential solutions on the design and application of gallium nitride(GaN) technology in hard-switching power electronic converters from the device level up to converter level. 展开更多
关键词 氮化镓 功率 电子变换器 电子技术
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Converted-wave diodic moveout and application in the land gas cloud area
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作者 张四海 李向阳 戴恒昌 《Applied Geophysics》 SCIE CSCD 2011年第3期171-180,239,共11页
PS converted-waves (C-waves) have been commonly used to image through gas clouds but the C-wave imaging may also be degraded by the diodic effect introduced by the gas cloud. It may be compensated for using a veloci... PS converted-waves (C-waves) have been commonly used to image through gas clouds but the C-wave imaging may also be degraded by the diodic effect introduced by the gas cloud. It may be compensated for using a velocity perturbation method which decouples the diodic moveout into two parts: the base velocity and the velocity perturbation. Gas clouds are widely distributed in the Sanhu area in the Qaidam basin of northwest China which is rich in natural gas. A land 2D3C seismic dataset is analyzed from the Sanhu area and significant diodic effects are observed in the data which harm the C-wave imaging. The diodic correction is applied to this data and the resultant C-wave imaging and the details of the reservoir structure are significantly improved. The diodic moveout plays an important role in working out the residu~ shear wave statics and the association of diodie correction and shear wave residual statics computation is a key step of C-wave high fidelity imaging in the gas cloud area. Finally, the new process workflow with diodic moveout is given. 展开更多
关键词 Diodic converted wave gas cloud base velocity PERTURBATION
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R&D and application of voltage sourced converter based high voltage direct current engineering technology in China 被引量:56
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作者 Guangfu TANG Zhiyuan HE Hui PANG 《Journal of Modern Power Systems and Clean Energy》 SCIE EI 2014年第1期1-15,共15页
As a new generation of direct current(DC)transmission technology,voltage sourced converter(VSC)based high voltage direct current(HVDC)has been widely developed and applied all over the world.China has also carried out... As a new generation of direct current(DC)transmission technology,voltage sourced converter(VSC)based high voltage direct current(HVDC)has been widely developed and applied all over the world.China has also carried out a deep technical research and engineering application in this area,and at present,it has been stepped into a fast growing period.This paper gives a general review over China’s VSC based HVDC in terms of engineering technology,application and future development.It comprehensively analyzes the technical difficulties and future development orientation on the aspects of the main configurations of VSC based HVDC system,topological structures of converters,control and protection technologies,flexible DC cables,converter valve tests,etc.It introduces the applicable fields and current status of China’s VSC based HVDC projects,and analyzes the application trends of VSC based HVDC projects both in China and all over the world according to the development characteristics and demands of future power grids. 展开更多
关键词 Voltage sourced converter based high voltage direct current(VSC based HVDC) Two-level converter Modular multi-level converter(MMC) Direct current grid(DC grid)
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Mode converter based on dual-core all-solid photonic bandgap fiber 被引量:4
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作者 Yong Jun Zhang Yuan Wang +3 位作者 Shan Yong Cai Ming Ying Lan Song Yu Wan Yi Gu 《Photonics Research》 SCIE EI 2015年第5期220-223,共4页
In this paper, we present a mode-selective coupler based on a dual-core all-solid photonic bandgap fiber(AS-PBGF). Because they are all-solid, AS-PBGF-based mode converters are easier to splice to other fibers than ... In this paper, we present a mode-selective coupler based on a dual-core all-solid photonic bandgap fiber(AS-PBGF). Because they are all-solid, AS-PBGF-based mode converters are easier to splice to other fibers than those based on air-hole photonic crystal fibers. Mode conversions between the LP01 and LP11modes, LP01 and LP21modes, and LP01 and LP02modes are obtained at the wavelength λ=1550 nm. The 3 dB wavelength bandwidth of these mode converters are 47.8,20.3, and 20.3 nm, respectively. 展开更多
关键词 core mode Mode converter based on dual-core all-solid photonic bandgap fiber LP PCF
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A DC Chopper Topology to Mitigate Commutation Failure of Line Commutated Converter Based High Voltage Direct Current Transmission 被引量:5
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作者 Chunyi Guo Bo Liu Chengyong Zhao 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2020年第2期345-355,共11页
To reduce the probability of commutation failure(CF)of a line commutated converter based high-voltage direct current(LCC-HVDC)transmission,a DC chopper topology composed of power consumption sub-modules based on thyri... To reduce the probability of commutation failure(CF)of a line commutated converter based high-voltage direct current(LCC-HVDC)transmission,a DC chopper topology composed of power consumption sub-modules based on thyristor full-bridge module(TFB-PCSM)is proposed.Firstly,the mechanism of the proposed topology to mitigate CF is analyzed,and the working modes of TFB-PCSM in different operation states are introduced.Secondly,the coordinated control strategy between the proposed DC chopper and LCC-HVDC is designed,and the voltage-current stresses of the TFB-PCSMs are investigated.Finally,the ability to mitigate the CF issues and the fault recovery performance of LCC-HVDC system are studied in PSCAD/EMTDC.The results show that the probability of CF of LCC-HVDC is significantly reduced,and the performances of fault recovery are effectively improved by the proposed DC chopper. 展开更多
关键词 Line commutated converter based high-voltage direct current(LCC-HVDC)transmission DC chopper power consumption sub-module based on thyristor full-bridge module(TFB-PCSM) commutation failure(CF) fault recovery capability
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Wideband signal detection based on high-speed photonic analog-to-digital converter 被引量:3
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作者 Guang Yang Weiwen Zou +1 位作者 Ye Yuan Jianping Chen 《Chinese Optics Letters》 SCIE EI CAS CSCD 2018年第3期6-10,共5页
This Letter demonstrates the effectiveness of a high-speed high-resolution photonic analog-to-digital converter (PADC) for wideband signal detection. The PADC system is seeded by a high-speed actively mode locked la... This Letter demonstrates the effectiveness of a high-speed high-resolution photonic analog-to-digital converter (PADC) for wideband signal detection. The PADC system is seeded by a high-speed actively mode locked laser, and the sampling rate is multiplied via a time-wavelength interleaving scheme. According to the laboratory test, an X-band linear frequency modulation signal is detected and digitized by the PADC system. The channel mismatch effect in wideband signal detection is compensated via an algorithm based on a short-time Fourier transform. Consequently, the signal-to-distortion ratio (SDR) of the wideband signal detection is enhanced to the comparable SDR of the single-tone signal detection. 展开更多
关键词 SDR Wideband signal detection based on high-speed photonic analog-to-digital converter LFM
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Single-ended Fault Detection Scheme Using Support Vector Machine for Multi-terminal Direct Current Systems Based on Modular Multilevel Converter 被引量:1
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作者 Guangyang Zhou Xiahui Zhang +2 位作者 Minxiao Han Shaahin Filizadeh Zhi Geng 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2023年第3期990-1000,共11页
This paper proposes a single-ended fault detection scheme for long transmission lines using support vector machine(SVM)for multi-terminal direct current systems based on modular multilevel converter(MMC-MTDC).The sche... This paper proposes a single-ended fault detection scheme for long transmission lines using support vector machine(SVM)for multi-terminal direct current systems based on modular multilevel converter(MMC-MTDC).The scheme overcomes existing detection difficulties in the protection of long transmission lines resulting from high grounding resistance and attenuation,and also avoids the sophisticated process of threshold value selection.The high-frequency components in the measured voltage extracted by a wavelet transform and the amplitude of the zero-mode set of the positive-sequence voltage are the inputs to a trained SVM.The output of the SVM determines the fault type.A model of a four-terminal DC power grid with overhead transmission lines is built in PSCAD/EMTDC.Simulation results of EMTDC confirm that the proposed scheme achieves 100%accuracy in detecting short-circuit faults with high resistance on long transmission lines.The proposed scheme eliminates mal-operation of DC circuit breakers when faced with power order changes or AC-side faults.Its robustness and time delay are also assessed and shown to have no perceptible effect on the speed and accuracy of the detection scheme,thus ensuring its reliability and stability. 展开更多
关键词 Fault detection short-circuit fault multi-terminal direct current systems based on modular multilevel converter support vector machine(SVM) wavelet transform
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Energy-based modeling and control for grid-side converter of doubly fed wind generator 被引量:1
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作者 Huihui SONG Yanbin QU 《控制理论与应用(英文版)》 EI 2012年第4期435-440,共6页
To avoid dealing with the zero dynamics limitation brought by the bidirectional power flow through the back-to-back converter in a doubly fed wind generator, a new energy-based modeling and control approach for the gr... To avoid dealing with the zero dynamics limitation brought by the bidirectional power flow through the back-to-back converter in a doubly fed wind generator, a new energy-based modeling and control approach for the grid- side converter is presented. During the modeling process, the grid-side converter is divided into two subsystems with the feedback interconnection structure, and the interactive matrix of the model takes into account the concrete port structure. Then, an energy-based controller is proposed to realize the grid-side control objectives based on the new model. Simulation studies are carried out in MATLAB/Simulink. Comparative results between the proportional-integral controller and the energy-based controller show that the latter one can obtain faster convergence rate and global stability as the load current varies. Moreover, the energy-based controller is also competent for grid-side control when simulated in a 2 MW wind energy conversion system with random wind. 展开更多
关键词 Wind energy Grid-side converter Energy-based control Port-controlled Hamilton
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Mode field converter based on embedded photonic crystal fiber
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作者 孙伟民 刘晓颀 +4 位作者 柴全 张建中 付枫华 姜宇 Tim A.Birks 《Chinese Optics Letters》 SCIE EI CAS CSCD 2009年第10期921-923,共3页
Six high-index cores are embedded around the central solid core of the photonic crystal fiber to form a fiber embedded photonic crystal fiber (FEPCF), which is investigated based on the beam propagation method. In t... Six high-index cores are embedded around the central solid core of the photonic crystal fiber to form a fiber embedded photonic crystal fiber (FEPCF), which is investigated based on the beam propagation method. In this structure, the Gaussian mode could be transferred to the ring mode. So FEPCF could used as a mode convertor. 展开更多
关键词 PCF MODE Mode field converter based on embedded photonic crystal fiber
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Efficiency and Output Power Evaluation of a Wavelength Converter Based on FWM in a Single Mode Fiber
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作者 B. C. Sarker S. P. Majumder T. Yoshino 《光学学报》 EI CAS CSCD 北大核心 2003年第S1期43-44,共2页
A frequency domain analysis is presented to determine the performance characteristics of a tunable all-optical wavelength converter using four-wave mixing (FWM) in a single mode fiber (SMF) around the zero dispersion ... A frequency domain analysis is presented to determine the performance characteristics of a tunable all-optical wavelength converter using four-wave mixing (FWM) in a single mode fiber (SMF) around the zero dispersion wavelength using two pump lasers. The output converted signal power as well as efficiency evaluated at a bit rate of 10 Gb/s show that the signal power is substantially higher at lower values of wavelength separation. 展开更多
关键词 FWM AS of Efficiency and Output Power Evaluation of a Wavelength converter based on FWM in a Single Mode Fiber in on
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A novel 40-Gb/s all-optical inverted wavelength converter based on a modified terahertz optical asymmetric demultiplexer
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作者 黄学田 叶培大 +1 位作者 张民 王凌 《Chinese Optics Letters》 SCIE EI CAS CSCD 2004年第12期691-693,共3页
A novel scheme for all-optical inverted wavelength conversion with 40-Gb/s pseudorandom bit sequences (PRBSs) based on a modified terahertz optical asymmetric demultiplexer (TOAD) is proposed. The performance of the p... A novel scheme for all-optical inverted wavelength conversion with 40-Gb/s pseudorandom bit sequences (PRBSs) based on a modified terahertz optical asymmetric demultiplexer (TOAD) is proposed. The performance of the proposed wavelength converter is analyzed in term of extinction ratio (ER) through numerical simulations. For a typical ER of 10 dB, some key characteristic parameters of the semiconductor optical amplifier (SOA) are designed. With the properly designed parameters, a high quality eye diagram is achievable, indicating that the amplitude fluctuation of the output signal is effectively reduced. 展开更多
关键词 SOA A novel 40-Gb/s all-optical inverted wavelength converter based on a modified terahertz optical asymmetric demultiplexer dBm length CCW
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Serum angiotensin-converting enzyme level for evaluating significant fibrosis in chronic hepatitis B 被引量:7
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作者 Ryuichi Noguchi Kosuke Kaji +9 位作者 Tadashi Namisaki Kei Moriya Mitsuteru Kitade Kosuke Takeda Hideto Kawaratani Yasushi Okura Yosuke Aihara Masanori Furukawa Akira Mitoro Hitoshi Yoshiji 《World Journal of Gastroenterology》 SCIE CAS 2017年第36期6705-6714,共10页
AIM To evaluate the diagnostic performance of angiotensinconverting enzyme(ACE)on significant liver fibrosis in patients with chronic hepatitis B(CHB). METHODS In total,100 patients with CHB who underwent liver biopsy... AIM To evaluate the diagnostic performance of angiotensinconverting enzyme(ACE)on significant liver fibrosis in patients with chronic hepatitis B(CHB). METHODS In total,100 patients with CHB who underwent liver biopsy in our hospital were enrolled,and 70 patients except for 30 patients with hypertension,fatty liver or habitual alcoholic consumption were analyzed.We compared histological liver fibrosis and serum ACE levels and evaluated the predictive potential to diagnose significant liver fibrosis by comparison with several biochemical marker-based indexes such as the aspartate aminotransferase(AST)-to-platelet ratio index(APRI),the fibrosis index based on four factors(FIB-4),the Mac-2 binding protein glycosylation isomer(M2BPGi)level and the number of platelets(Plt). RESULTS Serum ACE levels showed moderately positive correlation with liver fibrotic stages(R2=0.181).Patients with significant,advanced fibrosis and cirrhosis(F2-4)had significantly higher serum ACE levels than those with early-stage fibrosis and cirrhosis(F0-1).For significant fibrosis(≥F2),the 12.8 U/L cut-off value of ACE showed 91.7%sensitivity and 75.0%specificity.The receiver-operating characteristic(ROC)curves analysis revealed that the area under the curve(AUC)value of ACE was 0.871,which was higher than that of APRI,FIB-4,M2BPGi and Plt. CONCLUSION The serum ACE level could be a novel noninvasive,easy,accurate,and inexpensive marker of significant fibrosis stage in patients with CHB. 展开更多
关键词 Angiotensin-converting enzyme Hepatitis B virus Liver FIBROSIS Noninvasive FIBROSIS marker ASPARTATE aminotransferase-to-platelet ratio INDEX FIBROSIS INDEX based on four factors Mac-2 binding protein GLYCOSYLATION ISOMER
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