An efficient copper-catalyzed decarboxylative hydroboration of phenylpropiolic acids with bis（pinacolato）diboron was developed, affording b-vinylboronates as the only products in high yields. Extra hydrogen sources ...An efficient copper-catalyzed decarboxylative hydroboration of phenylpropiolic acids with bis（pinacolato）diboron was developed, affording b-vinylboronates as the only products in high yields. Extra hydrogen sources such as methanol are not needed in this catalytic system. This reaction could be performed successfully under ligand- and base-free conditions. It demonstrated that phenylpropiolic acids can be employed as alkyne synthons in the hydroboration reaction and exhibited good reactivity and higher selectivity than terminal alkynes.展开更多
Aromatic nitriles were synthesized through copper-catalyzed cyanations of aromatic bromides using benzoyl cyanide as the cyanide source.A series of functional groups were tolerated under the reaction conditions to pro...Aromatic nitriles were synthesized through copper-catalyzed cyanations of aromatic bromides using benzoyl cyanide as the cyanide source.A series of functional groups were tolerated under the reaction conditions to provide the products in good yields.Moreover,this protocol avoids using of highly toxic alkali cyanides and expensive palladium catalysts.展开更多
基金Financial support from the National Science Foundation of China (No. 21202049)the Recruitment Program of Global Experts (1000 Talents Plan)+2 种基金Fujian Hundred Talents PlanProgram of Innovative Research Team of Huaqiao UniversityInstrumental Analysis Center of Huaqiao University for analysis support
文摘An efficient copper-catalyzed decarboxylative hydroboration of phenylpropiolic acids with bis（pinacolato）diboron was developed, affording b-vinylboronates as the only products in high yields. Extra hydrogen sources such as methanol are not needed in this catalytic system. This reaction could be performed successfully under ligand- and base-free conditions. It demonstrated that phenylpropiolic acids can be employed as alkyne synthons in the hydroboration reaction and exhibited good reactivity and higher selectivity than terminal alkynes.
基金This project was financially supported by the National Natural Science Foundation of China(No.21302014)the Natural Science Foundation for Colleges and Universities of Jiangsu Province(13KJB150002)the Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology(grant No.BM2012110).
文摘Aromatic nitriles were synthesized through copper-catalyzed cyanations of aromatic bromides using benzoyl cyanide as the cyanide source.A series of functional groups were tolerated under the reaction conditions to provide the products in good yields.Moreover,this protocol avoids using of highly toxic alkali cyanides and expensive palladium catalysts.
