Purpose:To evaluate the clinical efficacy and safety of sulcus transscleral intraocular lens suture fixation with small incision through scleral tunnel in eyes the with posterior capsule defect or insufficient zonula ...Purpose:To evaluate the clinical efficacy and safety of sulcus transscleral intraocular lens suture fixation with small incision through scleral tunnel in eyes the with posterior capsule defect or insufficient zonula support. Methods:Thirty nine eyes with severe posterior capsule defect and zonula damages caused by small-incision cataract surgery,and those with capsule absence or intraocular lens dislocation were selected in this investigation from February 2007 to December 2009.Sulcus transscleral intraocular lens suture combined with puncture needle-guided external approach and."one- or two-point fixation" method in the small sclera tunnel incision were employed. Results:The mean follow-up was 12.1 months (range from 3 to 28 months). Six eyes were complicated by some eye diseases postoperatively.The best-corrected visual acuity was 20/40 or better in other 34 eyes.(87.17%).All eyes with secondary IOL fixation presented equal or better naked visual acuity than best-corrected visual acuity best-corrected preoperatively.No intraoperative and postoperative complications such as hemorrhage, retinal detachment, intraocular lens tilt and decentration occurred. Conclusion:Sulcus transscleral intraocular lens suture fixation via small sclera tunnel incision was easy to operate and master,required less operative time,and made primary intraocular lens fixation more effective in eyes with posterior capsule defect or insufficient zonula support in small sclera tunnel incision surgery.In addition,the technique was safe and effcacious for secondary intraocular lens fixation.展开更多
Objective:To study the effect of the conjunctival flap with limbus tunnel incision on change in tear function after phacoemulsification cataract surgery in diabetic cataract.Methods:One hundred and twenty patients wit...Objective:To study the effect of the conjunctival flap with limbus tunnel incision on change in tear function after phacoemulsification cataract surgery in diabetic cataract.Methods:One hundred and twenty patients with type 2diabetes(120 eyes)were enrolled,The patients were randomly divided into two groups,A:3.0mm clear corneal incision phacoemulsification cataract extraction and intraocular lens(IOL)implantation;sixty patients(60 eyes)in group,B:3.0mm conjunctival flap with limbus tunnel incision phacoemulsification cataract extraction and intraocular lens(IOL)implantation;sixty patients(60 eyes)in group.The difference of demographic characteristics between two groups were insignificant.Theocular surface disease index(OSDI),corneal sensation,break up time(BUT)and corneal fluorescein staining(FL)were examined preoperatively and 1wk,1 and 3mo postoperatively.Results:the OSDI score of group A was significantly higher than those of group B and the differences were statistically significant(P<0.05).The corneal sensation in two groups decreased after operations and the corneal sensation of group A was significantly lower than those of group B after surgery 1 week and 1 month、3month,and the differences were statistically significant(all P<0.05).the BUT in two groups decreased after operations and the BUT of group B was significantly better than those of group A after surgery,and the differences were statistically significant(P<0.05).At 1wk,1 and 3mo postoperatively,the FL score in two groups increased and the FL score of group A was significantly higher than those of group B and the differences were statistically significant(P<0.05).Conclusions:With conjunctival flap limbal tunnel incision,and the tunnel incision into the anterior chamber,closed more general limbal incision closed better,not easy infection and without the stitches,affecting small ocular tear film,This is especially suitable for patients with type 2 diabetes and cataract.It is worthy of clinical application.展开更多
Laser refractive surgery is one of the most commonly performed procedures worldwide.In laser refractive surgery,Femtosecond Laser in Situ Keratomileusis and Refractive Lenticule Extraction have emerged as promising al...Laser refractive surgery is one of the most commonly performed procedures worldwide.In laser refractive surgery,Femtosecond Laser in Situ Keratomileusis and Refractive Lenticule Extraction have emerged as promising alternatives to microkeratome Laser in Situ Keratomileusis and Photorefractive Keratectomy.Following laser refractive surgery,the corneal nerves,epithelial and stromal cells release neuromediators,including neurotrophins,neuropeptides and neurotransmitters.Notably,nerve growth factor,substance P,calcitonin gene-related peptide and various cytokines are important mediators of neurogenic inflammation and corneal nerve regeneration.Alterations in neuromediator profiles and ocular surface parameters following laser refractive surgery are attributed to the surgical techniques and the severity of tissue insult induced.In this review,we will discuss the(1)Functions of neuromediators and their physiological and clinical significance;(2)Changes in the neuromediators following various laser refractive surgeries;(3)Correlation between neuromediators,ocular surface health and corneal nerve status;and(4)Future directions,including the use of neuromediators as potential biomarkers for ocular surface health following laser refractive surgery,and as adjuncts to aid in corneal regeneration after laser refractive surgery.展开更多
AIM:To investigate and compare the visual and refractive outcomes of small incision lenticule extraction(SMILE),laser assisted sub-epithelial keratomileusis(LASEK),and LASEK combined with corneal collagen cross-linkin...AIM:To investigate and compare the visual and refractive outcomes of small incision lenticule extraction(SMILE),laser assisted sub-epithelial keratomileusis(LASEK),and LASEK combined with corneal collagen cross-linking(LASEKCXL)surgery in patients with less than 500μm of central corneal thickness(CCT).METHODS:The retrospective medical records review was conducted on the patients with CCT less than 500μm treated with SMILE,LASEK,and LASEK-CXL.There was a total of 172 eyes,76 eyes were in the SMILE group,53 eyes in the LASEK group,and 43 eyes in the LASEK-CXL group.Uncorrected distance visual acuity(UDVA),spherical equivalent refraction(SE),and corneal haze were followed up in the three groups for 12 mo.RESULTS:At 12 mo postoperatively,there were no statistically significant differences in UDVA and in the absolute value of SE between the three groups.The predictability within±0.50 D in the SMILE group(85.5%)was significantly higher than in both the LASEK group(64.2%,P<0.01)and the LASEK-CXL group(69.8%,P=0.04).The efficacy index and safety index were not significantly different among the three groups.Corneal haze at 12 mo postoperatively was higher in the LASEK-CXL group(27.9%)than in the SMILE group(2.6%,P<0.01)and in the LASEK group(7.5%,P<0.01).CONCLUSION:In patients with CCT less than 500μm,SMILE,LASEK,and LASEK-CXL appear to be effective for myopic correction.Among them,SMILE surgery shows the highest predictability.展开更多
AIM: To evaluate the clinical and functional results after repair of distal biceps tendon tears, following the Morrey's modified double-incision approach.METHODS: We retrospectively reviewed 47 patients with dista...AIM: To evaluate the clinical and functional results after repair of distal biceps tendon tears, following the Morrey's modified double-incision approach.METHODS: We retrospectively reviewed 47 patients with distal rupture of biceps brachii treated between2003 and 2012 in our Orthopedic Department with muscle-splitting double-incision technique. Outcome measures included the Mayo elbow performance, the DASH questionnaire, patient's satisfaction, elbow and forearm motion, grip strength and complications occurrence.RESULTS: At an average 18 mo follow-up(range, 7 mo-10 years) the average Mayo elbow performance and DASH score were respectively 97.2 and 4.8. The elbow flexion range was 94%, extension was-2°, supination was 93% and pronation 96% compared with the uninjured limb. The mean grip strength, expressed as percentage of respective contralateral limb, was 83%. The average patient satisfaction rating on a Likert scale(from 0 to 10) was 9.4. The following complications were observed: 3 cases of heterotopic ossification(6.4%), one(2.1%) re-rupture of the tendon at the site of reattachment and 2 cases(4.3%) of posterior interosseous nerve palsy. No complication required further surgical treatment.CONCLUSION: This technique allows an anatomic reattachment of distal biceps tendon at the radial tuberosity providing full functional recovery with low complication rate.展开更多
基金Science and technology project of Fujian Province(2008F3031)
文摘Purpose:To evaluate the clinical efficacy and safety of sulcus transscleral intraocular lens suture fixation with small incision through scleral tunnel in eyes the with posterior capsule defect or insufficient zonula support. Methods:Thirty nine eyes with severe posterior capsule defect and zonula damages caused by small-incision cataract surgery,and those with capsule absence or intraocular lens dislocation were selected in this investigation from February 2007 to December 2009.Sulcus transscleral intraocular lens suture combined with puncture needle-guided external approach and."one- or two-point fixation" method in the small sclera tunnel incision were employed. Results:The mean follow-up was 12.1 months (range from 3 to 28 months). Six eyes were complicated by some eye diseases postoperatively.The best-corrected visual acuity was 20/40 or better in other 34 eyes.(87.17%).All eyes with secondary IOL fixation presented equal or better naked visual acuity than best-corrected visual acuity best-corrected preoperatively.No intraoperative and postoperative complications such as hemorrhage, retinal detachment, intraocular lens tilt and decentration occurred. Conclusion:Sulcus transscleral intraocular lens suture fixation via small sclera tunnel incision was easy to operate and master,required less operative time,and made primary intraocular lens fixation more effective in eyes with posterior capsule defect or insufficient zonula support in small sclera tunnel incision surgery.In addition,the technique was safe and effcacious for secondary intraocular lens fixation.
基金It is supported by Youth cultivation fund of the first affiliated hospital of Hainan Medical University(Number:HYFYPY20160).
文摘Objective:To study the effect of the conjunctival flap with limbus tunnel incision on change in tear function after phacoemulsification cataract surgery in diabetic cataract.Methods:One hundred and twenty patients with type 2diabetes(120 eyes)were enrolled,The patients were randomly divided into two groups,A:3.0mm clear corneal incision phacoemulsification cataract extraction and intraocular lens(IOL)implantation;sixty patients(60 eyes)in group,B:3.0mm conjunctival flap with limbus tunnel incision phacoemulsification cataract extraction and intraocular lens(IOL)implantation;sixty patients(60 eyes)in group.The difference of demographic characteristics between two groups were insignificant.Theocular surface disease index(OSDI),corneal sensation,break up time(BUT)and corneal fluorescein staining(FL)were examined preoperatively and 1wk,1 and 3mo postoperatively.Results:the OSDI score of group A was significantly higher than those of group B and the differences were statistically significant(P<0.05).The corneal sensation in two groups decreased after operations and the corneal sensation of group A was significantly lower than those of group B after surgery 1 week and 1 month、3month,and the differences were statistically significant(all P<0.05).the BUT in two groups decreased after operations and the BUT of group B was significantly better than those of group A after surgery,and the differences were statistically significant(P<0.05).At 1wk,1 and 3mo postoperatively,the FL score in two groups increased and the FL score of group A was significantly higher than those of group B and the differences were statistically significant(P<0.05).Conclusions:With conjunctival flap limbal tunnel incision,and the tunnel incision into the anterior chamber,closed more general limbal incision closed better,not easy infection and without the stitches,affecting small ocular tear film,This is especially suitable for patients with type 2 diabetes and cataract.It is worthy of clinical application.
文摘Laser refractive surgery is one of the most commonly performed procedures worldwide.In laser refractive surgery,Femtosecond Laser in Situ Keratomileusis and Refractive Lenticule Extraction have emerged as promising alternatives to microkeratome Laser in Situ Keratomileusis and Photorefractive Keratectomy.Following laser refractive surgery,the corneal nerves,epithelial and stromal cells release neuromediators,including neurotrophins,neuropeptides and neurotransmitters.Notably,nerve growth factor,substance P,calcitonin gene-related peptide and various cytokines are important mediators of neurogenic inflammation and corneal nerve regeneration.Alterations in neuromediator profiles and ocular surface parameters following laser refractive surgery are attributed to the surgical techniques and the severity of tissue insult induced.In this review,we will discuss the(1)Functions of neuromediators and their physiological and clinical significance;(2)Changes in the neuromediators following various laser refractive surgeries;(3)Correlation between neuromediators,ocular surface health and corneal nerve status;and(4)Future directions,including the use of neuromediators as potential biomarkers for ocular surface health following laser refractive surgery,and as adjuncts to aid in corneal regeneration after laser refractive surgery.
文摘AIM:To investigate and compare the visual and refractive outcomes of small incision lenticule extraction(SMILE),laser assisted sub-epithelial keratomileusis(LASEK),and LASEK combined with corneal collagen cross-linking(LASEKCXL)surgery in patients with less than 500μm of central corneal thickness(CCT).METHODS:The retrospective medical records review was conducted on the patients with CCT less than 500μm treated with SMILE,LASEK,and LASEK-CXL.There was a total of 172 eyes,76 eyes were in the SMILE group,53 eyes in the LASEK group,and 43 eyes in the LASEK-CXL group.Uncorrected distance visual acuity(UDVA),spherical equivalent refraction(SE),and corneal haze were followed up in the three groups for 12 mo.RESULTS:At 12 mo postoperatively,there were no statistically significant differences in UDVA and in the absolute value of SE between the three groups.The predictability within±0.50 D in the SMILE group(85.5%)was significantly higher than in both the LASEK group(64.2%,P<0.01)and the LASEK-CXL group(69.8%,P=0.04).The efficacy index and safety index were not significantly different among the three groups.Corneal haze at 12 mo postoperatively was higher in the LASEK-CXL group(27.9%)than in the SMILE group(2.6%,P<0.01)and in the LASEK group(7.5%,P<0.01).CONCLUSION:In patients with CCT less than 500μm,SMILE,LASEK,and LASEK-CXL appear to be effective for myopic correction.Among them,SMILE surgery shows the highest predictability.
文摘AIM: To evaluate the clinical and functional results after repair of distal biceps tendon tears, following the Morrey's modified double-incision approach.METHODS: We retrospectively reviewed 47 patients with distal rupture of biceps brachii treated between2003 and 2012 in our Orthopedic Department with muscle-splitting double-incision technique. Outcome measures included the Mayo elbow performance, the DASH questionnaire, patient's satisfaction, elbow and forearm motion, grip strength and complications occurrence.RESULTS: At an average 18 mo follow-up(range, 7 mo-10 years) the average Mayo elbow performance and DASH score were respectively 97.2 and 4.8. The elbow flexion range was 94%, extension was-2°, supination was 93% and pronation 96% compared with the uninjured limb. The mean grip strength, expressed as percentage of respective contralateral limb, was 83%. The average patient satisfaction rating on a Likert scale(from 0 to 10) was 9.4. The following complications were observed: 3 cases of heterotopic ossification(6.4%), one(2.1%) re-rupture of the tendon at the site of reattachment and 2 cases(4.3%) of posterior interosseous nerve palsy. No complication required further surgical treatment.CONCLUSION: This technique allows an anatomic reattachment of distal biceps tendon at the radial tuberosity providing full functional recovery with low complication rate.