AIM： To analyze the correlations between ocular biomechanical and biometric data of the eye,measured by Scheimpflug-based devices on healthy subjects.METHODS： Three consecutive measurements were carried out using th...AIM： To analyze the correlations between ocular biomechanical and biometric data of the eye,measured by Scheimpflug-based devices on healthy subjects.METHODS： Three consecutive measurements were carried out using the corneal visualization Scheimpflug technology（Cor Vis ST） device on healthy eyes and the 10 device-specific parameters were recorded.Pentacam HR-derived parameters（corneal curvature radii on the anterior and posterior surfaces;apical pachymetry;corneal volume;corneal aberration data;depth,volume and angle of the anterior chamber） and axial length（AL） from IOLMaster were correlated with the 10 specific CorV is ST parameters.RESULTS： Measurements were conducted in 43 eyes of 43 volunteers（age 61.24±15.72y）.The 10 specific Cor Vis ST data showed significant relationships with corneal curvature radii both on the anterior and posterior surface,pachymetric data,root mean square（RMS） data of lower-order aberrations,and posterior RMS of higher-order aberrations and spherical aberration of the posterior cornea.Anterior chamber depth showed a significant relationship,but there were no significant correlations between corneal volume,anterior chamber volume,mean chamber angle or AL and the 10 specific CorV is ST parameters.CONCLUSION： Cor Vis ST-generated parameters are influenced by corneal curvature radii,some corneal RMS data,but corneal volume,anterior chamber volume,chamber angle and AL have no correlation with the biomechan-ical parameters.The parameters measured by CorV is ST seem to refer mostly to corneal properties of the eye.展开更多
目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并...目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并按中央角膜厚度(central corneal thickness,CCT)将患者分为3组:薄角膜组(CCT≤520μm)、正常角膜组(520μm<CCT≤570μm)、厚角膜组(CCT>570μm),分别采用Corvis ST、A超、Lenstar三种仪器测量3组患者的中央角膜厚度,并纳入对比指标。结果:Cor vis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组的测量值对比差异均有统计学意义(均P<0.05);在相关性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组呈正相关(r=0.841,P<0.001 vs r=0.832,P<0.001;r=0.866,P<0.001 vs r=0.918,P<0.001;r=0.497,P<0.001 vs r=0.801,P<0.001);在一致性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组上一致性系数ICC及95%置信区间分别为0.602(0.091,0.857),0.758(0.221,0.901)、0.741(0.207,0.890),0.845(0.396,0.938)、0.417(0.005,0.679),0.667(0.172,0.851),95%一致性区间范围分别是(−2.2~24.2μm,−6.7~19.5μm;−8.4~24.6μm,−6.8~19.4μm;−8.7~23.8μm,−7.0~18.3μm)。结论:通过对3组数据统计分析得出,Corvis ST与A超、Lens tar的测量值相比,差异均有统计学意义,且Corvis ST的测量值均高于后两种仪器;Cor vis ST与后两者均有着较高的相关性,且在正常角膜厚度测量上相关性最高;在一致性方面,从ICC点估计及95%置信区间数值分析,一致性较差;从Bland-Altman角度分析,Corvis ST与后两者的绝对值最大差值超过10μm,一致性较差,但在与Lenstar的绝对值最大差值均在20μm内。因此,在测量精度要求较高的屈光手术筛查方面,Corvis ST与A超、Lenstar之间不能相互替代,而对于大规模临床筛查,其角膜厚度测量值对眼压的影响有一定的临床参考意义。展开更多
文摘AIM： To analyze the correlations between ocular biomechanical and biometric data of the eye,measured by Scheimpflug-based devices on healthy subjects.METHODS： Three consecutive measurements were carried out using the corneal visualization Scheimpflug technology（Cor Vis ST） device on healthy eyes and the 10 device-specific parameters were recorded.Pentacam HR-derived parameters（corneal curvature radii on the anterior and posterior surfaces;apical pachymetry;corneal volume;corneal aberration data;depth,volume and angle of the anterior chamber） and axial length（AL） from IOLMaster were correlated with the 10 specific CorV is ST parameters.RESULTS： Measurements were conducted in 43 eyes of 43 volunteers（age 61.24±15.72y）.The 10 specific Cor Vis ST data showed significant relationships with corneal curvature radii both on the anterior and posterior surface,pachymetric data,root mean square（RMS） data of lower-order aberrations,and posterior RMS of higher-order aberrations and spherical aberration of the posterior cornea.Anterior chamber depth showed a significant relationship,but there were no significant correlations between corneal volume,anterior chamber volume,mean chamber angle or AL and the 10 specific CorV is ST parameters.CONCLUSION： Cor Vis ST-generated parameters are influenced by corneal curvature radii,some corneal RMS data,but corneal volume,anterior chamber volume,chamber angle and AL have no correlation with the biomechan-ical parameters.The parameters measured by CorV is ST seem to refer mostly to corneal properties of the eye.
文摘目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并按中央角膜厚度(central corneal thickness,CCT)将患者分为3组:薄角膜组(CCT≤520μm)、正常角膜组(520μm<CCT≤570μm)、厚角膜组(CCT>570μm),分别采用Corvis ST、A超、Lenstar三种仪器测量3组患者的中央角膜厚度,并纳入对比指标。结果:Cor vis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组的测量值对比差异均有统计学意义(均P<0.05);在相关性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组呈正相关(r=0.841,P<0.001 vs r=0.832,P<0.001;r=0.866,P<0.001 vs r=0.918,P<0.001;r=0.497,P<0.001 vs r=0.801,P<0.001);在一致性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组上一致性系数ICC及95%置信区间分别为0.602(0.091,0.857),0.758(0.221,0.901)、0.741(0.207,0.890),0.845(0.396,0.938)、0.417(0.005,0.679),0.667(0.172,0.851),95%一致性区间范围分别是(−2.2~24.2μm,−6.7~19.5μm;−8.4~24.6μm,−6.8~19.4μm;−8.7~23.8μm,−7.0~18.3μm)。结论:通过对3组数据统计分析得出,Corvis ST与A超、Lens tar的测量值相比,差异均有统计学意义,且Corvis ST的测量值均高于后两种仪器;Cor vis ST与后两者均有着较高的相关性,且在正常角膜厚度测量上相关性最高;在一致性方面,从ICC点估计及95%置信区间数值分析,一致性较差;从Bland-Altman角度分析,Corvis ST与后两者的绝对值最大差值超过10μm,一致性较差,但在与Lenstar的绝对值最大差值均在20μm内。因此,在测量精度要求较高的屈光手术筛查方面,Corvis ST与A超、Lenstar之间不能相互替代,而对于大规模临床筛查,其角膜厚度测量值对眼压的影响有一定的临床参考意义。
基金Supported by Xi'an Social Development Research Project Grant[No.SF1513(2)]Shaanxi Social Development Research Project Grant(No.2016SF-274)Shaanxi Provincial Health Research Project(No.2016E002)~~
文摘目的:应用可视化角膜生物力学分析仪(Corvis ST)及眼反应分析仪(ORA)评估飞秒激光制瓣准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)术后角膜生物力学变化,并分析与其他参数的相关性。方法:收集63例飞秒制瓣LASIK手术患者,所有收集对象采用右眼数据进行分析。角膜生物力学测量仪器应用可视化角膜生物力学分析仪Corvis ST及眼反应分析仪ORA,手术前及手术后1mo进行生物力学数据采集分析。配对t检验或Mann-Whitney U检验进行手术前后生物力学对比分析。Pearson或Spearman统计学方法进行相关性分析。结果:与FS-LASIK手术前相比,手术后1stA-time,Vin,2ndA length,Vout以及Radius下降,有统计学差异(P=0.00,P=0.00,P=0.00,P=0.00,P=0.00)。2ndA-time,DA以及PD手术后增加,有统计学差异(P=0.00,P=0.00,P=0.00)。1stA length以及HC time手术后改变不明显,无统计学差异(P=0.96,P=0.08)。与FS-LASIK手术前相比,手术后CH,CRF下降,有统计学差异(P=0.00,P=0.00)。手术后1stA-time,2ndA-time,DA and Radius变化量与手术前角膜中央厚度有明显相关性(P=0.01,P=0.04,P=0.03,P=0.01)。结论:飞秒激光LASIK手术后角膜生物力学参数有较明显改变,可通过Corvis ST及ORA生物力学参数计算得出相应变化,手术后生物力学参数变化与角膜厚度相关性明显。
