Stuck up and fracture of coronary angioplasty hardware are unwonted complications of percutaneous coronary interventions (PCI) for which surgical retrieval and management is once in a while required. We present one ca...Stuck up and fracture of coronary angioplasty hardware are unwonted complications of percutaneous coronary interventions (PCI) for which surgical retrieval and management is once in a while required. We present one case of a 59-year-old diabetic, a hypertensive gentleman who attended the emergency room (ER) with central chest pain for 2 hours. After evaluation of the patient <span>by physical and noninvasive diagnostic tests, he was diagnosed as a case of</span> acute myocardial infarction (AMI) with stable hemodynamic. For the aforementioned findings, the patient was treated first with a thrombolytic agent in <span>ER and then shifted to Cardiology Department for monitoring and further</span> <span>coronary evaluation by coronary angiography (CAG). CAG revealed essen</span><span>tially single vessel disease (SVD) with complex left anterior descending (LAD) </span>artery lesion, so PCI was attempted but failed with an unfortunate incidence of the broken delivery shaft and left <i>in vivo</i>. Immediate decision making and <span>surgical management for retrieval of lost angioplasty device and correction</span> coronary lesion with revascularization save the patient from grave complica<span>tion. All the series of events and management approaches of this very com</span>plex coronary artery lesion are discussed in this article.展开更多
Objective To study the clinical value of coronary stenting in treatment of severe complex coronary artery lesions, to evaluate the short and long term outcome of the patients imployed coronary stents, and to well reco...Objective To study the clinical value of coronary stenting in treatment of severe complex coronary artery lesions, to evaluate the short and long term outcome of the patients imployed coronary stents, and to well recognize the role of stenting in dealing with the complications of PTCA.Methods In this study, two hundrad sixty four patients with coronary artery disease were included, who were classified as PTCA group (138 cases)and coronary stented group(126 cases).They all received Exercise Test(ET)、Ultrasound Cardiogram(UCG)and Ambulatory Electrocardiography (AECG)at admission and before discharge, respectively. The coronary artery lesions were categorized into type A.B.C according to the methods reported by ACC/AHA . It was that the data between two groups including clinical information, cronary artery lesion characteristicis, procedural success rate, major complications, Minimum Lumen Diameter (MLD),residual stenosis, collateral circulation scores both before and after procedure had been compared. Following up were performed 6 months to 3 years after procedure. Results The study showed that there were no significant different in two groups including the clinical information, positive rate of ET, EF, results of AECG. But the rate of type B2/C lesions were higher in CS group than that in PTCA group( P <0.05). Both PTCA Group and CS Group had extremely success rate in type A and type B1, but CS had a higher success rate than that in PTCA in type B2 and type C (94.28%VS 89.2%, P <0.05). CS group had a lower rate of complication in procedure than that of PTCA group. There are no signifiance in MLD between the two groups (0.53± 0.22)mm vs (0.42±0.26)mm,( P >0.05) before procedure. But MLD was signifantly higher in CS group than that in PTCA group (2.51±0.66)mm vs (3.08±0.66)mm,( P <0.001) after procedure.The collateral circulation scrores were signifantly decreased after procedure (1.7±0.6) vs (0.8±0.4); (2.1±0.3) vs (0.3±0.4) in both PTCA Group and PTCA Group respectivesly,( P <0.001). Residual stenosis were higher in PTCA group(15±6%)than that in CS group (6±3%, P <0.001). The positive rate of ET, exercise capacity, ST depressions, EF and wall motion were all improved significantly both in PTCA group and CS group, CS group has a higher effect in exercise capacity, MLD, EF and ischemia duration.Seventy nine patients were followed up and the rate of cardiac events in the CS group were lower than in PTCA group.Conclusions 1.Coronary stenting had a high success rate and low complication in treatment of severe and complex coronary artery lesions.2.Coronary stentig reduced residual stenosis, improved blood supply, salvaged the hibernating and /or stunned myocardium, improved the left ventricular function. CS have offered a new, safe and effective metbods for treatment of left main trunk lesions; 3.Coronary stenting has broden the indication for invasive treatment of coronary artery diseases.展开更多
Objective:The optimal percutaneous coronary intervention(PCI)technique for bifurcation lesions remains controversial,especially considering the variability of the side branch(SB).A provisional stenting technique is cu...Objective:The optimal percutaneous coronary intervention(PCI)technique for bifurcation lesions remains controversial,especially considering the variability of the side branch(SB).A provisional stenting technique is currently recommended in most cases.This meta-analysis aimed to compare outcomes of different bifurcation PCI strategies,clarifying their scope of application.Methods:Randomized controlled trials comparing PCI strategies for coronary bifurcation lesions were systematically retrieved from PubMed,Cochrane,Web of Science,and EBSCO literature databases without limitations on published date or language.Major adverse cardiovascular events(MACEs)were stipulated as main outcomes.Secondary outcomes of interest were all-cause mortality,cardiovascular mortality,target lesion revascularization(TLR),target vessel revascularization,myocardial infarction(MI),and stent thrombosis.Both pooled analysis and sub-group analysis were performed.Results:Twenty-three randomized controlled trials with 6380 participants were included.Eighteen studies compared the provisional strategy with 2-stent approaches.No significant difference in MACEs(relative risk(RR),1.16;95%confidence interval(CI),0.90-1.48;I2=62%)was found between 1-stent and 2-stent techniques.However,when SB lesion length was used as the separation condition,the 2-stent strategy was associated with fewer MACEs(RR,1.87;95%CI,1.46-2.41;I2=70%),TLRs(RR,2.13;95%CI,1.50-3.02;I2=59%),and MIs(RR,2.17;95%CI,1.19-3.95;I2=52%)than the provisional strategy in those where SB lesions measured>10 mm long.Conclusions:In the current work,there was no significant difference between 1-stent and 2-stent techniques in terms of MACEs or secondary outcomes.However,2-stent approaches have clinical advantages over the provisional strategy in bifurcation when the SB lesion length is>10 mm due to fewer cases of TLR and MI.展开更多
文摘Stuck up and fracture of coronary angioplasty hardware are unwonted complications of percutaneous coronary interventions (PCI) for which surgical retrieval and management is once in a while required. We present one case of a 59-year-old diabetic, a hypertensive gentleman who attended the emergency room (ER) with central chest pain for 2 hours. After evaluation of the patient <span>by physical and noninvasive diagnostic tests, he was diagnosed as a case of</span> acute myocardial infarction (AMI) with stable hemodynamic. For the aforementioned findings, the patient was treated first with a thrombolytic agent in <span>ER and then shifted to Cardiology Department for monitoring and further</span> <span>coronary evaluation by coronary angiography (CAG). CAG revealed essen</span><span>tially single vessel disease (SVD) with complex left anterior descending (LAD) </span>artery lesion, so PCI was attempted but failed with an unfortunate incidence of the broken delivery shaft and left <i>in vivo</i>. Immediate decision making and <span>surgical management for retrieval of lost angioplasty device and correction</span> coronary lesion with revascularization save the patient from grave complica<span>tion. All the series of events and management approaches of this very com</span>plex coronary artery lesion are discussed in this article.
文摘Objective To study the clinical value of coronary stenting in treatment of severe complex coronary artery lesions, to evaluate the short and long term outcome of the patients imployed coronary stents, and to well recognize the role of stenting in dealing with the complications of PTCA.Methods In this study, two hundrad sixty four patients with coronary artery disease were included, who were classified as PTCA group (138 cases)and coronary stented group(126 cases).They all received Exercise Test(ET)、Ultrasound Cardiogram(UCG)and Ambulatory Electrocardiography (AECG)at admission and before discharge, respectively. The coronary artery lesions were categorized into type A.B.C according to the methods reported by ACC/AHA . It was that the data between two groups including clinical information, cronary artery lesion characteristicis, procedural success rate, major complications, Minimum Lumen Diameter (MLD),residual stenosis, collateral circulation scores both before and after procedure had been compared. Following up were performed 6 months to 3 years after procedure. Results The study showed that there were no significant different in two groups including the clinical information, positive rate of ET, EF, results of AECG. But the rate of type B2/C lesions were higher in CS group than that in PTCA group( P <0.05). Both PTCA Group and CS Group had extremely success rate in type A and type B1, but CS had a higher success rate than that in PTCA in type B2 and type C (94.28%VS 89.2%, P <0.05). CS group had a lower rate of complication in procedure than that of PTCA group. There are no signifiance in MLD between the two groups (0.53± 0.22)mm vs (0.42±0.26)mm,( P >0.05) before procedure. But MLD was signifantly higher in CS group than that in PTCA group (2.51±0.66)mm vs (3.08±0.66)mm,( P <0.001) after procedure.The collateral circulation scrores were signifantly decreased after procedure (1.7±0.6) vs (0.8±0.4); (2.1±0.3) vs (0.3±0.4) in both PTCA Group and PTCA Group respectivesly,( P <0.001). Residual stenosis were higher in PTCA group(15±6%)than that in CS group (6±3%, P <0.001). The positive rate of ET, exercise capacity, ST depressions, EF and wall motion were all improved significantly both in PTCA group and CS group, CS group has a higher effect in exercise capacity, MLD, EF and ischemia duration.Seventy nine patients were followed up and the rate of cardiac events in the CS group were lower than in PTCA group.Conclusions 1.Coronary stenting had a high success rate and low complication in treatment of severe and complex coronary artery lesions.2.Coronary stentig reduced residual stenosis, improved blood supply, salvaged the hibernating and /or stunned myocardium, improved the left ventricular function. CS have offered a new, safe and effective metbods for treatment of left main trunk lesions; 3.Coronary stenting has broden the indication for invasive treatment of coronary artery diseases.
基金funded by grants from the Nanjing Health Science and Technology Development Special Fund Project(ZKX20034)the Jiangsu Provincial Special Program of Medical Science(BE2019615).
文摘Objective:The optimal percutaneous coronary intervention(PCI)technique for bifurcation lesions remains controversial,especially considering the variability of the side branch(SB).A provisional stenting technique is currently recommended in most cases.This meta-analysis aimed to compare outcomes of different bifurcation PCI strategies,clarifying their scope of application.Methods:Randomized controlled trials comparing PCI strategies for coronary bifurcation lesions were systematically retrieved from PubMed,Cochrane,Web of Science,and EBSCO literature databases without limitations on published date or language.Major adverse cardiovascular events(MACEs)were stipulated as main outcomes.Secondary outcomes of interest were all-cause mortality,cardiovascular mortality,target lesion revascularization(TLR),target vessel revascularization,myocardial infarction(MI),and stent thrombosis.Both pooled analysis and sub-group analysis were performed.Results:Twenty-three randomized controlled trials with 6380 participants were included.Eighteen studies compared the provisional strategy with 2-stent approaches.No significant difference in MACEs(relative risk(RR),1.16;95%confidence interval(CI),0.90-1.48;I2=62%)was found between 1-stent and 2-stent techniques.However,when SB lesion length was used as the separation condition,the 2-stent strategy was associated with fewer MACEs(RR,1.87;95%CI,1.46-2.41;I2=70%),TLRs(RR,2.13;95%CI,1.50-3.02;I2=59%),and MIs(RR,2.17;95%CI,1.19-3.95;I2=52%)than the provisional strategy in those where SB lesions measured>10 mm long.Conclusions:In the current work,there was no significant difference between 1-stent and 2-stent techniques in terms of MACEs or secondary outcomes.However,2-stent approaches have clinical advantages over the provisional strategy in bifurcation when the SB lesion length is>10 mm due to fewer cases of TLR and MI.