The Einstein ring is usually explained in the framework of the gravitational lens. Conversely here we apply the framework of the expansion of a superbubble (SB) in order to explain the spherical appearance of the ring...The Einstein ring is usually explained in the framework of the gravitational lens. Conversely here we apply the framework of the expansion of a superbubble (SB) in order to explain the spherical appearance of the ring. Two classical equations of motion for SBs are derived in the presence of a linear and a trigonometric decrease for density. A relativistic equation of motion with an inverse square dependence for the density is derived. The angular distance, adopting the minimax approximation, is derived for three relativistic cosmologies: the standard, the flat and the wCDM. We derive the relation between redshift and Euclidean distance, which allows fixing the radius of the Einstein ring. The details of the ring are explained by a simple version of the theory of images.展开更多
This article concerns the integral related to the transverse comoving distance and, in turn, to the luminosity distance both in the standard non-flat and flat cosmology. The purpose is to determine a straightforward m...This article concerns the integral related to the transverse comoving distance and, in turn, to the luminosity distance both in the standard non-flat and flat cosmology. The purpose is to determine a straightforward mathematical formulation for the luminosity distance as function of the transverse comoving distance for all cosmology cases with a non-zero cosmological constant by adopting a different mindset. The applied method deals with incomplete elliptical integrals of the first kind associated with the polynomial roots admitted in the comoving distance integral according to the scientific literature. The outcome shows that the luminosity distance can be obtained by the combination of an analytical solution followed by a numerical integration in order to account for the redshift. This solution is solely compared to the current Gaussian quadrature method used as basic recognized algorithm in standard cosmology.展开更多
Three mechanisms for an alternative to the Doppler effect as an explanation for the redshift are reviewed. A fourth mechanism is the attenuation of the light as given by the Beer-Lambert law. The average value of the ...Three mechanisms for an alternative to the Doppler effect as an explanation for the redshift are reviewed. A fourth mechanism is the attenuation of the light as given by the Beer-Lambert law. The average value of the Hubble constant is therefore derived by processing the galaxies of the NED-D catalog in which the distances are independent of the redshift. The observed anisotropy of the Hubble constant is reproduced by adopting a rim model, a chord model, and both 2D and 3D Voronoi diagrams.展开更多
This paper introduces the two Upsilon constants to the reader. Their usefulness is described with respect to acting as coupling constants between the CMB temperature and the Hubble constant. In addition, this paper su...This paper introduces the two Upsilon constants to the reader. Their usefulness is described with respect to acting as coupling constants between the CMB temperature and the Hubble constant. In addition, this paper summarizes the current state of quantum cosmology with respect to the Flat Space Cosmology (FSC) model. Although the FSC quantum cosmology formulae were published in 2018, they are only rearrangements and substitutions of the other assumptions into the original FSC Hubble temperature formula. In a real sense, this temperature formula was the first quantum cosmology formula developed since Hawking’s black hole temperature formula. A recent development in the last month proves that the FSC Hubble temperature formula can be derived from the Stephan-Boltzmann law. Thus, this Hubble temperature formula effectively unites some quantum developments with the general relativity model inherent in FSC. More progress towards unification in the near-future is expected.展开更多
This paper shows how the Flat Space Cosmology model correlates the recom-bination epoch CMB temperature of 3000 K with a cosmological redshift of 1100. This proof is given in support of the recent publication that the...This paper shows how the Flat Space Cosmology model correlates the recom-bination epoch CMB temperature of 3000 K with a cosmological redshift of 1100. This proof is given in support of the recent publication that the Tatum and Seshavatharam Hubble temperature formulae can be derived using the Stephan-Boltzmann dispersion law. Thus, as explained herein, the era of high precision Planck scale quantum cosmology has arrived.展开更多
Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter lea...Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter leads to the disagreement in the galaxy clustering amplitude, quantified by the parameter S8. Within the same model we described the Hubble tension. We described also the mechanism that transforms the gravitational collapse into an explosion—it concerns the dynamics of virtual fields that lead to dark energy. Our calculations concern the Type Ia supernovae and the core-collapse supernovae. We calculated the quantized masses of the progenitors of supernovae, emitted total energy during explosion, and we calculated how much of the released energy was transferred to neutrinos. Value of the speed of sound in the strongly interacting matter measured at the LHC confirms that presented here model is correct. Our calculations show that the Universe is cyclic.展开更多
We develop a theory of cosmology, which is not based on the cosmological principle. We achieve this without violating the Copernican principle. It is well known that the gravitational redshift associated with the Schw...We develop a theory of cosmology, which is not based on the cosmological principle. We achieve this without violating the Copernican principle. It is well known that the gravitational redshift associated with the Schwarzschild solution applied to the distant supernova does not lead to the observed redsift-distance relationship. We show, however, that generalizations of the Schwarzschild metric, the Taub-NUT metrics, do indeed lead to the observed redshift-distance relationship and to the observed time dilation. These universes are not expanding rather the observed cosmological redshift is due to the gravitational redshift associated with these solutions. Time dilation in these stationary universes has the same dependency on redshift that generally has been seen as proof that space is expanding. Our theory resolves the Hubble tension.展开更多
This paper is a further elaboration of the author’s Time Dilation Cosmology (TDC) holographic model that ties gravitation and celestial mechanics and kinematics directly to time dilation, resolving all the major conu...This paper is a further elaboration of the author’s Time Dilation Cosmology (TDC) holographic model that ties gravitation and celestial mechanics and kinematics directly to time dilation, resolving all the major conundrums in astrophysics, and ties astrophysics directly to quantum physics. It begins with a brief summary of the TDC model and contains the new derivation for the time dilation version of the formula for summing relativistic velocities, Einstein’s gravitational constant and the time dilation versions for the Lorentz factor and the Euclidean norm of the 3d velocity vector, the two of which can then be used in the Four-velocity formula. It is demonstrated how orbital curvature is manifested as the resultant of two time dilation-manifested velocities. It also explains why an interferometer cannot distinguish free fall from zero gravity and further elaborates on the author’s previous explanations of how spiral galaxies are formed, and contains mathematical proof that Black Holes are actually Magnetospheric Eternally Collapsing Objects (MECOs) that are massless spacetime vortices.展开更多
This paper reports a detailed study of generalized Chaplygin gas(GCG)with power law form of scale factor and truncated form of the scale factor using binomial expansion in both interacting and non-interacting scenario...This paper reports a detailed study of generalized Chaplygin gas(GCG)with power law form of scale factor and truncated form of the scale factor using binomial expansion in both interacting and non-interacting scenarios along with its cosmological consequences,studied in terms of equation of state(EoS)parameter.In the non-interacting scenario,the EoS parameter behaves as quintessence in both forms of the scale factor.In the interacting scenario,the EoS parameter behaves as phantom and for the truncated form of the scale factor,it violates the constraints of the positive parameterα.The cosmological implementation of GCG interacting with pressureless dark matter is investigated in the framework of f(T)modified gravity,where T is the torsion scalar in teleparallelism.The interaction term is directly proportional to the GCG density with positive coupling constant.In f(T)gravity,the EoS is behaving like phantom.The stability of the reconstructed model is investigated and it is found to be stable against small gravitational perturbations,i.e.,the squared speed of sound is non-negative and an increasing function of cosmic time t.We have observed that our reconstructed f(T)model satisfies one of the sufficient conditions of a realistic reconstructed model and it is consistent with the CMB constraints and primordial nucleosynthesis.Cosmology of primordial perturbations has also been analyzed and the self-interacting potential has been found to be an increasing function of cosmic time t.展开更多
In this letter, we report on our trials to remove the instability of black holes in brane world cosmological models consisting of two branes and a bulk. In order to resolve this problem, general types of interaction p...In this letter, we report on our trials to remove the instability of black holes in brane world cosmological models consisting of two branes and a bulk. In order to resolve this problem, general types of interaction potentials were employed. Careful analyses have shown that although the black holes instabilities were removed, a sort of arbitrariness adherent to the motion of the two branes towards each other has taken place leading to an unstable system. Thus, the models seem to us rather paradoxical.展开更多
This model ties gravitation and celestial mechanics and kinematics directly to time dilation. It is a new theory of cosmology and the evolution of galaxies. Space and time are not two separate things, but two aspects ...This model ties gravitation and celestial mechanics and kinematics directly to time dilation. It is a new theory of cosmology and the evolution of galaxies. Space and time are not two separate things, but two aspects of a single thing, “spacetime”. Whatever affects space, affects time, and vice-versa. If time speeds up, space must contract to maintain the speed of light, c, and when space thickens into a mass, it is harder to evolve forward, and time appears to slow. If spatial events are spinning as time passes, then the forward direction of time is spinning. This is Einstein’s curvature in the forward direction of time. Herein, the basis is outlined for time dilation cosmology in a spacetime/quantum continuum, including the time dilation-based derivation of the mass of the Cosmic Microwave Background Radiation (CMBR), and time dilation formulas are derived for stellar system orbital, and galactic rotation, velocities, the force in time in Newtons, the Hamiltonian, the Hubble shift, the empirical gravitational constant, G, and other formulas, showing their direct relationship to the difference in the rate of time between the far distant observer’s invariant 1 s/s rate of time and the slower rate of time at the coordinate point, proving the universe is not composed of separate bodies moving through space, but is an evolving 3-dimensional holographic continuum containing varying densities evolving forward in the forward direction of time, the 4th dimension, at apparently different rates of time, the velocities merely being compensation for those slower rates of time in a continuum evolving forward overall at c, which is why light propagates at c, even from a moving source. As per General Relativity, if there is no rate of time difference between coordinate points, there is no gravitational attraction between those points, and no gravitationally induced velocity. This model resolves all the major conundrums in astrophysics, eliminating Dark Energy and Dark Matter, and ties astrophysics directly to quantum physics.展开更多
BACKGROUND Colorectal cancer(CRC)is a serious threat worldwide.Although early screening is suggested to be the most effective method to prevent and control CRC,the current situation of early screening for CRC is still...BACKGROUND Colorectal cancer(CRC)is a serious threat worldwide.Although early screening is suggested to be the most effective method to prevent and control CRC,the current situation of early screening for CRC is still not optimistic.In China,the incidence of CRC in the Yangtze River Delta region is increasing dramatically,but few studies have been conducted.Therefore,it is necessary to develop a simple and efficient early screening model for CRC.AIM To develop and validate an early-screening nomogram model to identify individuals at high risk of CRC.METHODS Data of 64448 participants obtained from Ningbo Hospital,China between 2014 and 2017 were retrospectively analyzed.The cohort comprised 64448 individuals,of which,530 were excluded due to missing or incorrect data.Of 63918,7607(11.9%)individuals were considered to be high risk for CRC,and 56311(88.1%)were not.The participants were randomly allocated to a training set(44743)or validation set(19175).The discriminatory ability,predictive accuracy,and clinical utility of the model were evaluated by constructing and analyzing receiver operating characteristic(ROC)curves and calibration curves and by decision curve analysis.Finally,the model was validated internally using a bootstrap resampling technique.RESULTS Seven variables,including demographic,lifestyle,and family history information,were examined.Multifactorial logistic regression analysis revealed that age[odds ratio(OR):1.03,95%confidence interval(CI):1.02-1.03,P<0.001],body mass index(BMI)(OR:1.07,95%CI:1.06-1.08,P<0.001),waist circumference(WC)(OR:1.03,95%CI:1.02-1.03 P<0.001),lifestyle(OR:0.45,95%CI:0.42-0.48,P<0.001),and family history(OR:4.28,95%CI:4.04-4.54,P<0.001)were the most significant predictors of high-risk CRC.Healthy lifestyle was a protective factor,whereas family history was the most significant risk factor.The area under the curve was 0.734(95%CI:0.723-0.745)for the final validation set ROC curve and 0.735(95%CI:0.728-0.742)for the training set ROC curve.The calibration curve demonstrated a high correlation between the CRC high-risk population predicted by the nomogram model and the actual CRC high-risk population.CONCLUSION The early-screening nomogram model for CRC prediction in high-risk populations developed in this study based on age,BMI,WC,lifestyle,and family history exhibited high accuracy.展开更多
This article poses the question of a minimum cosmological constant, i.e. vacuum energy at the start of the cosmological evolution from a near singularity. We pose this comparing formalism as given by Berry (1976) as t...This article poses the question of a minimum cosmological constant, i.e. vacuum energy at the start of the cosmological evolution from a near singularity. We pose this comparing formalism as given by Berry (1976) as to a small time length, and compare that in its entirety to compare this value given by Berry (1976) with a minimum time length at the start of cosmological space-time evolution. Using the methodology of Zeldovich (1972) as to a problem with electron-positron pair production we also propose another upper bound to the problem of minimum time length which may be accessible to experimental inquiry. This then makes the problem of minimum time length a way of specifying a magnetic field dependence of the cosmological constant, which has major implications to answering if quintessence, i.e. a changing cosmological vacuum energy, or a constant for the “cosmological constant” problem. Our answer is an initial value for the cosmological vacuum energy 10<sup>10</sup> - 10<sup>20</sup> times greater than today which suggests either Quintessence, or if still a constant, a much better value for this parameter than what is suggested by traditional field theory methods. In closing we review how our construct supports work done by Corda, as to early universe models and what the implications are, as to the choices we have made.展开更多
The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~10.In the scenari...The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~10.In the scenario of a low or moderate star formation efficiency,because massive neutrinos tend to suppress the growth of structure of the universe,the JWST observation tightens the upper bound of the neutrino masses.Assuming A cold dark matter cosmology and a star formation efficiency∈[0.05,0.3](flat prior),we perform joint analyses of Planck+JWST and Planck+BAO+JWST,and obtain improved constraints∑m_(ν)<0.196 eV and ∑m_(ν)+<0.111 eV at 95% confidence level,respectively.Based on the above assumptions,the inverted mass ordering,which implies ∑m_(ν)≥0.1 eV,is excluded by Planck+BAO+JWST at 92.7% confidence level.展开更多
In 1937, P. Dirac proposed the Large Number Hypothesis and the Hypothesis of the variable gravitational “constant”, and later added the notion of continuous creation of Matter in the World. The Hypersphere World-Uni...In 1937, P. Dirac proposed the Large Number Hypothesis and the Hypothesis of the variable gravitational “constant”, and later added the notion of continuous creation of Matter in the World. The Hypersphere World-Universe Model (WUM) follows these ideas, albeit introducing a different mechanism of Matter creation. In this paper, we show that Gravitational parameter G that can be measured directly makes measurable all Cosmological parameters, which cannot be measured directly.展开更多
We develop a Python tool to estimate the tail distribution of the number of dark matter halos beyond a mass threshold and in a given volume in a light-cone.The code is based on the extended Press-Schechter model and i...We develop a Python tool to estimate the tail distribution of the number of dark matter halos beyond a mass threshold and in a given volume in a light-cone.The code is based on the extended Press-Schechter model and is computationally efficient,typically taking a few seconds on a personal laptop for a given set of cosmological parameters.The high efficiency of the code allows a quick estimation of the tension between cosmological models and the red candidate massive galaxies released by the James Webb Space Telescope,as well as scanning the theory space with the Markov Chain Monte Carlo method.As an example application,we use the tool to study the cosmological implication of the candidate galaxies presented in Labbéet al.The standard Λcold dark matter(ΛCDM)model is well consistent with the data if the star formation efficiency can reach~0.3 at high redshift.For a low star formation efficiency ε~0.1,theΛCDM model is disfavored at~2σ-3σconfidence level.展开更多
The Multi-channel Photometric Survey Telescope(Mephisto)is a real-time,three-color photometric system designed to capture the color evolution of stars and transients accurately.This telescope system can be crucial in ...The Multi-channel Photometric Survey Telescope(Mephisto)is a real-time,three-color photometric system designed to capture the color evolution of stars and transients accurately.This telescope system can be crucial in cosmological distance measurements of low-redshift(low-z,z■0.1)Type Ia supernovae(SNe Ia).To optimize the capabilities of this instrument,we perform a comprehensive simulation study before its official operation is scheduled to start.By considering the impact of atmospheric extinction,weather conditions,and the lunar phase at the observing site involving the instrumental features,we simulate light curves of SNe Ia obtained by Mephisto.The best strategy in the case of SN Ia cosmology is to take the image at an exposure time of 130 s with a cadence of 3 days.In this condition,Mephisto can obtain hundreds of high-quality SNe Ia to achieve a distance measurement better than 4.5%.Given the on-time spectral classification and monitoring of the Lijiang 2.4 m Telescope at the same observatory,Mephisto,in the whole operation,can significantly enrich the well-calibrated sample of supernovae at low-z and improve the calibration accuracy of high-z SNe Ia.展开更多
Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is...Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is a major problem in this part of the world. This non-union is a major treatment challenge with increased cost of care and morbidity in this part of the world. Humeral shaft non-union can be treated with locked intra-medullary nailing (LIMN) or dynamic compression plating (DCP). Study on comparison of these methods of fixation in this part of the world is scarce in literature search, hence the reason for this study. Objective: The objectives of this study are: (1) to compare early clinical outcome following fixation of humeral shaft fracture nonunion with DCP versus LIMN;(2) to compare the time of radiologic fracture union of DCP with LIMN;(3) to compare complications following fixation of humeral shaft fracture nonunion with DCP versus LIMN. Patients and Methods: This was a randomized control study done for 2 years in which fifty adult patients with humeral shaft non-union were recruited. The patients were grouped into 2 (P = DCP & N = LIMN). Forty five of the patients completed the follow up periods of the study and then analyzed. The P group had ORIF with DCP while the N group had ORIF with LIMN. Both groups had grafting with cancellous bones. Each patient was followed up for a period of 6 months at the time which radiographic union is expected. Any patient without clinical and/or radiographic evidence of union after six months of surgery was diagnosed as having recurrent non-union. The data generated was analyzed using SPSS Version 23. The results were presented in charts and tables. The paired t-test was used while considering p value Result: Forty five patients completed follow up. There was a male preponderance (4:1), right humerus predominated (3:2). Motor vehicular accidents were the commonest cause of the fractures (62%). Most non-union fractures occurred at the level of the middle 3<sup>rd</sup> of the humeral shaft (60%). Failed TBS treatment was the commonest indication for the osteosynthesis (71%). More patients had plating (53%) compared to 47% who had LIMN. Most patients (93.4%) had union between 3 to 6 months irrespective of fixation type with no significant statistical difference between the union rate of DCP and LIMN (p value 0.06) with similar functional outcome and complication rates irrespective of the type of fixation. Conclusion: This study showed that the success rates in term of fracture union, outcome functional grades and complication rates were not directly dependent on the types of the fixation: plating or locked intra-medullary nailing.展开更多
This editorial comments on the article by Qu et al in a recent edition of World Journal of Gastrointestinal Oncology,focusing on the importance of early diagnosis in managing esophageal cancer and strategies for achie...This editorial comments on the article by Qu et al in a recent edition of World Journal of Gastrointestinal Oncology,focusing on the importance of early diagnosis in managing esophageal cancer and strategies for achieving“early detection”.The five-year age-standardized net survival for esophageal cancer patients falls short of expectations.Early detection and accurate diagnosis are critical strategies for improving the treatment outcomes of esophageal cancer.While advancements in endoscopic technology have been significant,there seems to be an excessive emphasis on the latest high-end endoscopic devices and various endoscopic resection techniques.Therefore,it is imperative to redirect focus towards proactive early detection strategies for esophageal cancer,investigate the most cost-effective screening methods suitable for different regions,and persistently explore practical solutions to improve the five-year survival rate of patients with esophageal cancer.展开更多
BACKGROUND Gastric cancer is a common malignant tumor of the digestive tract,and endosco-pic submucosal dissection(ESD)is the preferred treatment for early-stage gastric cancer.The analysis of the epidemiological char...BACKGROUND Gastric cancer is a common malignant tumor of the digestive tract,and endosco-pic submucosal dissection(ESD)is the preferred treatment for early-stage gastric cancer.The analysis of the epidemiological characteristics of gastric mucosal tumors with different differentiation degrees and the influencing factors of long-term ESD efficacy may have certain significance for revealing the development of gastric cancer and ESD.AIM To analyze the features of gastric mucosal tumors at different differentiation levels,and to explore the prognostic factors of ESD.METHODS We retrospectively studied 301 lesions in 285 patients at The Second Affiliated Hospital of Xi'an Jiaotong University from 2014 to 2021,according to the latest Japanese guidelines(sixth edition),and divided them into low-grade intrae-pithelial neoplasia(LGIN),high-grade intraepithelial neoplasia(HGIN),and computed tomography at 3,6 and 12 months after ESD.We compared clinicopathologic characteristics,ESD efficacy,and complications with different degrees of differentiation,and analyzed the related factors associated with ESD.RESULTS HGIN and differentiated carcinoma patients were significantly older compared with LGIN patients(P<0.001)and accounted for more 0-IIc(P<0.001),atrophic gastritis was common(P<0.001),and irregular microvascular patterns(IMVPs)and demarcation lines(DLs)were more obvious(P<0.001).There was more infiltration in the undifferentiated carcinoma tissue(P<0.001),more abnormal folds and poorer mucosal peristalsis(P<0.001),and more obvious IMVPs,irregular microsurface patterns and DLs(P<0.05)than in the LGIN and HGIN tissues.The disease-free survival rates at 2,5,and 8 years after ESD were 95.0%,90.1%,and 86.9%,respectively.Undifferen-tiated lesions(HR 5.066),white moss(HR 7.187),incomplete resection(HR 3.658),and multiple primary cancers(HR 2.462)were significantly associated with poor prognosis.CONCLUSION Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics,which are closely related to the safety and efficacy of ESD.展开更多
文摘The Einstein ring is usually explained in the framework of the gravitational lens. Conversely here we apply the framework of the expansion of a superbubble (SB) in order to explain the spherical appearance of the ring. Two classical equations of motion for SBs are derived in the presence of a linear and a trigonometric decrease for density. A relativistic equation of motion with an inverse square dependence for the density is derived. The angular distance, adopting the minimax approximation, is derived for three relativistic cosmologies: the standard, the flat and the wCDM. We derive the relation between redshift and Euclidean distance, which allows fixing the radius of the Einstein ring. The details of the ring are explained by a simple version of the theory of images.
文摘This article concerns the integral related to the transverse comoving distance and, in turn, to the luminosity distance both in the standard non-flat and flat cosmology. The purpose is to determine a straightforward mathematical formulation for the luminosity distance as function of the transverse comoving distance for all cosmology cases with a non-zero cosmological constant by adopting a different mindset. The applied method deals with incomplete elliptical integrals of the first kind associated with the polynomial roots admitted in the comoving distance integral according to the scientific literature. The outcome shows that the luminosity distance can be obtained by the combination of an analytical solution followed by a numerical integration in order to account for the redshift. This solution is solely compared to the current Gaussian quadrature method used as basic recognized algorithm in standard cosmology.
文摘Three mechanisms for an alternative to the Doppler effect as an explanation for the redshift are reviewed. A fourth mechanism is the attenuation of the light as given by the Beer-Lambert law. The average value of the Hubble constant is therefore derived by processing the galaxies of the NED-D catalog in which the distances are independent of the redshift. The observed anisotropy of the Hubble constant is reproduced by adopting a rim model, a chord model, and both 2D and 3D Voronoi diagrams.
文摘This paper introduces the two Upsilon constants to the reader. Their usefulness is described with respect to acting as coupling constants between the CMB temperature and the Hubble constant. In addition, this paper summarizes the current state of quantum cosmology with respect to the Flat Space Cosmology (FSC) model. Although the FSC quantum cosmology formulae were published in 2018, they are only rearrangements and substitutions of the other assumptions into the original FSC Hubble temperature formula. In a real sense, this temperature formula was the first quantum cosmology formula developed since Hawking’s black hole temperature formula. A recent development in the last month proves that the FSC Hubble temperature formula can be derived from the Stephan-Boltzmann law. Thus, this Hubble temperature formula effectively unites some quantum developments with the general relativity model inherent in FSC. More progress towards unification in the near-future is expected.
文摘This paper shows how the Flat Space Cosmology model correlates the recom-bination epoch CMB temperature of 3000 K with a cosmological redshift of 1100. This proof is given in support of the recent publication that the Tatum and Seshavatharam Hubble temperature formulae can be derived using the Stephan-Boltzmann dispersion law. Thus, as explained herein, the era of high precision Planck scale quantum cosmology has arrived.
文摘Here, using the Scale-Symmetric Theory (SST) we explain the cosmological tension and the origin of the largest cosmic structures. We show that a change in value of strong coupling constant for cold baryonic matter leads to the disagreement in the galaxy clustering amplitude, quantified by the parameter S8. Within the same model we described the Hubble tension. We described also the mechanism that transforms the gravitational collapse into an explosion—it concerns the dynamics of virtual fields that lead to dark energy. Our calculations concern the Type Ia supernovae and the core-collapse supernovae. We calculated the quantized masses of the progenitors of supernovae, emitted total energy during explosion, and we calculated how much of the released energy was transferred to neutrinos. Value of the speed of sound in the strongly interacting matter measured at the LHC confirms that presented here model is correct. Our calculations show that the Universe is cyclic.
文摘We develop a theory of cosmology, which is not based on the cosmological principle. We achieve this without violating the Copernican principle. It is well known that the gravitational redshift associated with the Schwarzschild solution applied to the distant supernova does not lead to the observed redsift-distance relationship. We show, however, that generalizations of the Schwarzschild metric, the Taub-NUT metrics, do indeed lead to the observed redshift-distance relationship and to the observed time dilation. These universes are not expanding rather the observed cosmological redshift is due to the gravitational redshift associated with these solutions. Time dilation in these stationary universes has the same dependency on redshift that generally has been seen as proof that space is expanding. Our theory resolves the Hubble tension.
文摘This paper is a further elaboration of the author’s Time Dilation Cosmology (TDC) holographic model that ties gravitation and celestial mechanics and kinematics directly to time dilation, resolving all the major conundrums in astrophysics, and ties astrophysics directly to quantum physics. It begins with a brief summary of the TDC model and contains the new derivation for the time dilation version of the formula for summing relativistic velocities, Einstein’s gravitational constant and the time dilation versions for the Lorentz factor and the Euclidean norm of the 3d velocity vector, the two of which can then be used in the Four-velocity formula. It is demonstrated how orbital curvature is manifested as the resultant of two time dilation-manifested velocities. It also explains why an interferometer cannot distinguish free fall from zero gravity and further elaborates on the author’s previous explanations of how spiral galaxies are formed, and contains mathematical proof that Black Holes are actually Magnetospheric Eternally Collapsing Objects (MECOs) that are massless spacetime vortices.
基金financial support from the Council of Scientific and Industrial Research(Government of India)with Grant No.03(1420)/18/EMR-II。
文摘This paper reports a detailed study of generalized Chaplygin gas(GCG)with power law form of scale factor and truncated form of the scale factor using binomial expansion in both interacting and non-interacting scenarios along with its cosmological consequences,studied in terms of equation of state(EoS)parameter.In the non-interacting scenario,the EoS parameter behaves as quintessence in both forms of the scale factor.In the interacting scenario,the EoS parameter behaves as phantom and for the truncated form of the scale factor,it violates the constraints of the positive parameterα.The cosmological implementation of GCG interacting with pressureless dark matter is investigated in the framework of f(T)modified gravity,where T is the torsion scalar in teleparallelism.The interaction term is directly proportional to the GCG density with positive coupling constant.In f(T)gravity,the EoS is behaving like phantom.The stability of the reconstructed model is investigated and it is found to be stable against small gravitational perturbations,i.e.,the squared speed of sound is non-negative and an increasing function of cosmic time t.We have observed that our reconstructed f(T)model satisfies one of the sufficient conditions of a realistic reconstructed model and it is consistent with the CMB constraints and primordial nucleosynthesis.Cosmology of primordial perturbations has also been analyzed and the self-interacting potential has been found to be an increasing function of cosmic time t.
文摘In this letter, we report on our trials to remove the instability of black holes in brane world cosmological models consisting of two branes and a bulk. In order to resolve this problem, general types of interaction potentials were employed. Careful analyses have shown that although the black holes instabilities were removed, a sort of arbitrariness adherent to the motion of the two branes towards each other has taken place leading to an unstable system. Thus, the models seem to us rather paradoxical.
文摘This model ties gravitation and celestial mechanics and kinematics directly to time dilation. It is a new theory of cosmology and the evolution of galaxies. Space and time are not two separate things, but two aspects of a single thing, “spacetime”. Whatever affects space, affects time, and vice-versa. If time speeds up, space must contract to maintain the speed of light, c, and when space thickens into a mass, it is harder to evolve forward, and time appears to slow. If spatial events are spinning as time passes, then the forward direction of time is spinning. This is Einstein’s curvature in the forward direction of time. Herein, the basis is outlined for time dilation cosmology in a spacetime/quantum continuum, including the time dilation-based derivation of the mass of the Cosmic Microwave Background Radiation (CMBR), and time dilation formulas are derived for stellar system orbital, and galactic rotation, velocities, the force in time in Newtons, the Hamiltonian, the Hubble shift, the empirical gravitational constant, G, and other formulas, showing their direct relationship to the difference in the rate of time between the far distant observer’s invariant 1 s/s rate of time and the slower rate of time at the coordinate point, proving the universe is not composed of separate bodies moving through space, but is an evolving 3-dimensional holographic continuum containing varying densities evolving forward in the forward direction of time, the 4th dimension, at apparently different rates of time, the velocities merely being compensation for those slower rates of time in a continuum evolving forward overall at c, which is why light propagates at c, even from a moving source. As per General Relativity, if there is no rate of time difference between coordinate points, there is no gravitational attraction between those points, and no gravitationally induced velocity. This model resolves all the major conundrums in astrophysics, eliminating Dark Energy and Dark Matter, and ties astrophysics directly to quantum physics.
基金Supported by the Project of NINGBO Leading Medical Health Discipline,No.2022-B11Ningbo Natural Science Foundation,No.202003N4206Public Welfare Foundation of Ningbo,No.2021S108.
文摘BACKGROUND Colorectal cancer(CRC)is a serious threat worldwide.Although early screening is suggested to be the most effective method to prevent and control CRC,the current situation of early screening for CRC is still not optimistic.In China,the incidence of CRC in the Yangtze River Delta region is increasing dramatically,but few studies have been conducted.Therefore,it is necessary to develop a simple and efficient early screening model for CRC.AIM To develop and validate an early-screening nomogram model to identify individuals at high risk of CRC.METHODS Data of 64448 participants obtained from Ningbo Hospital,China between 2014 and 2017 were retrospectively analyzed.The cohort comprised 64448 individuals,of which,530 were excluded due to missing or incorrect data.Of 63918,7607(11.9%)individuals were considered to be high risk for CRC,and 56311(88.1%)were not.The participants were randomly allocated to a training set(44743)or validation set(19175).The discriminatory ability,predictive accuracy,and clinical utility of the model were evaluated by constructing and analyzing receiver operating characteristic(ROC)curves and calibration curves and by decision curve analysis.Finally,the model was validated internally using a bootstrap resampling technique.RESULTS Seven variables,including demographic,lifestyle,and family history information,were examined.Multifactorial logistic regression analysis revealed that age[odds ratio(OR):1.03,95%confidence interval(CI):1.02-1.03,P<0.001],body mass index(BMI)(OR:1.07,95%CI:1.06-1.08,P<0.001),waist circumference(WC)(OR:1.03,95%CI:1.02-1.03 P<0.001),lifestyle(OR:0.45,95%CI:0.42-0.48,P<0.001),and family history(OR:4.28,95%CI:4.04-4.54,P<0.001)were the most significant predictors of high-risk CRC.Healthy lifestyle was a protective factor,whereas family history was the most significant risk factor.The area under the curve was 0.734(95%CI:0.723-0.745)for the final validation set ROC curve and 0.735(95%CI:0.728-0.742)for the training set ROC curve.The calibration curve demonstrated a high correlation between the CRC high-risk population predicted by the nomogram model and the actual CRC high-risk population.CONCLUSION The early-screening nomogram model for CRC prediction in high-risk populations developed in this study based on age,BMI,WC,lifestyle,and family history exhibited high accuracy.
文摘This article poses the question of a minimum cosmological constant, i.e. vacuum energy at the start of the cosmological evolution from a near singularity. We pose this comparing formalism as given by Berry (1976) as to a small time length, and compare that in its entirety to compare this value given by Berry (1976) with a minimum time length at the start of cosmological space-time evolution. Using the methodology of Zeldovich (1972) as to a problem with electron-positron pair production we also propose another upper bound to the problem of minimum time length which may be accessible to experimental inquiry. This then makes the problem of minimum time length a way of specifying a magnetic field dependence of the cosmological constant, which has major implications to answering if quintessence, i.e. a changing cosmological vacuum energy, or a constant for the “cosmological constant” problem. Our answer is an initial value for the cosmological vacuum energy 10<sup>10</sup> - 10<sup>20</sup> times greater than today which suggests either Quintessence, or if still a constant, a much better value for this parameter than what is suggested by traditional field theory methods. In closing we review how our construct supports work done by Corda, as to early universe models and what the implications are, as to the choices we have made.
基金supported by the National SKA Program of China No.2020SKA0110402the National Natural Science Foundationof China(NSFC)under grant No.12073088the National Key R&D Program of China(grant No.2020YFC2201600)。
文摘The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~10.In the scenario of a low or moderate star formation efficiency,because massive neutrinos tend to suppress the growth of structure of the universe,the JWST observation tightens the upper bound of the neutrino masses.Assuming A cold dark matter cosmology and a star formation efficiency∈[0.05,0.3](flat prior),we perform joint analyses of Planck+JWST and Planck+BAO+JWST,and obtain improved constraints∑m_(ν)<0.196 eV and ∑m_(ν)+<0.111 eV at 95% confidence level,respectively.Based on the above assumptions,the inverted mass ordering,which implies ∑m_(ν)≥0.1 eV,is excluded by Planck+BAO+JWST at 92.7% confidence level.
文摘In 1937, P. Dirac proposed the Large Number Hypothesis and the Hypothesis of the variable gravitational “constant”, and later added the notion of continuous creation of Matter in the World. The Hypersphere World-Universe Model (WUM) follows these ideas, albeit introducing a different mechanism of Matter creation. In this paper, we show that Gravitational parameter G that can be measured directly makes measurable all Cosmological parameters, which cannot be measured directly.
基金supported by the National Key R&D Program of China(grant No.2020YFC2201600)the National Natural Science Foundation of China(NSFC,grant No.12073088)the National SKA Program of China(grant No.2020SKA0110402)。
文摘We develop a Python tool to estimate the tail distribution of the number of dark matter halos beyond a mass threshold and in a given volume in a light-cone.The code is based on the extended Press-Schechter model and is computationally efficient,typically taking a few seconds on a personal laptop for a given set of cosmological parameters.The high efficiency of the code allows a quick estimation of the tension between cosmological models and the red candidate massive galaxies released by the James Webb Space Telescope,as well as scanning the theory space with the Markov Chain Monte Carlo method.As an example application,we use the tool to study the cosmological implication of the candidate galaxies presented in Labbéet al.The standard Λcold dark matter(ΛCDM)model is well consistent with the data if the star formation efficiency can reach~0.3 at high redshift.For a low star formation efficiency ε~0.1,theΛCDM model is disfavored at~2σ-3σconfidence level.
基金supported by the National Key R&D Program of China(2021YFA1600404)the National Natural Science Foundation of China(NSFC,grant No.12173082)+11 种基金science research grants from the China Manned Space Project(CMS-CSST-2021-A12)the Yunnan Province Foundation(202201AT070069)the Top-notch Young Talents Program of Yunnan Provincethe Light of West China Program provided by the Chinese Academy of Sciencesthe International Centre of Supernovae,Yunnan Key Laboratory(202302AN360001)Funding for the LJT has been provided by the CAS and the People’s Government of Yunnan Provincefunded by the“Yunnan University Development Plan for World-Class University”“Yunnan University Development Plan for World-Class Astronomy Discipline”obtained supports from the“Science&Technology Champion Project”(202005AB160002)from two“Team Projects”—the“Innovation Team”(202105AE160021)the“Top Team”(202305AT350002)funded by the“Yunnan Revitalization Talent Support Program.”。
文摘The Multi-channel Photometric Survey Telescope(Mephisto)is a real-time,three-color photometric system designed to capture the color evolution of stars and transients accurately.This telescope system can be crucial in cosmological distance measurements of low-redshift(low-z,z■0.1)Type Ia supernovae(SNe Ia).To optimize the capabilities of this instrument,we perform a comprehensive simulation study before its official operation is scheduled to start.By considering the impact of atmospheric extinction,weather conditions,and the lunar phase at the observing site involving the instrumental features,we simulate light curves of SNe Ia obtained by Mephisto.The best strategy in the case of SN Ia cosmology is to take the image at an exposure time of 130 s with a cadence of 3 days.In this condition,Mephisto can obtain hundreds of high-quality SNe Ia to achieve a distance measurement better than 4.5%.Given the on-time spectral classification and monitoring of the Lijiang 2.4 m Telescope at the same observatory,Mephisto,in the whole operation,can significantly enrich the well-calibrated sample of supernovae at low-z and improve the calibration accuracy of high-z SNe Ia.
文摘Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is a major problem in this part of the world. This non-union is a major treatment challenge with increased cost of care and morbidity in this part of the world. Humeral shaft non-union can be treated with locked intra-medullary nailing (LIMN) or dynamic compression plating (DCP). Study on comparison of these methods of fixation in this part of the world is scarce in literature search, hence the reason for this study. Objective: The objectives of this study are: (1) to compare early clinical outcome following fixation of humeral shaft fracture nonunion with DCP versus LIMN;(2) to compare the time of radiologic fracture union of DCP with LIMN;(3) to compare complications following fixation of humeral shaft fracture nonunion with DCP versus LIMN. Patients and Methods: This was a randomized control study done for 2 years in which fifty adult patients with humeral shaft non-union were recruited. The patients were grouped into 2 (P = DCP & N = LIMN). Forty five of the patients completed the follow up periods of the study and then analyzed. The P group had ORIF with DCP while the N group had ORIF with LIMN. Both groups had grafting with cancellous bones. Each patient was followed up for a period of 6 months at the time which radiographic union is expected. Any patient without clinical and/or radiographic evidence of union after six months of surgery was diagnosed as having recurrent non-union. The data generated was analyzed using SPSS Version 23. The results were presented in charts and tables. The paired t-test was used while considering p value Result: Forty five patients completed follow up. There was a male preponderance (4:1), right humerus predominated (3:2). Motor vehicular accidents were the commonest cause of the fractures (62%). Most non-union fractures occurred at the level of the middle 3<sup>rd</sup> of the humeral shaft (60%). Failed TBS treatment was the commonest indication for the osteosynthesis (71%). More patients had plating (53%) compared to 47% who had LIMN. Most patients (93.4%) had union between 3 to 6 months irrespective of fixation type with no significant statistical difference between the union rate of DCP and LIMN (p value 0.06) with similar functional outcome and complication rates irrespective of the type of fixation. Conclusion: This study showed that the success rates in term of fracture union, outcome functional grades and complication rates were not directly dependent on the types of the fixation: plating or locked intra-medullary nailing.
基金Supported by the Education and Teaching Reform Project,the First Clinical College of Chongqing Medical University,No.CMER202305Program for Youth Innovation in Future Medicine,Chongqing Medical University,No.W0138.
文摘This editorial comments on the article by Qu et al in a recent edition of World Journal of Gastrointestinal Oncology,focusing on the importance of early diagnosis in managing esophageal cancer and strategies for achieving“early detection”.The five-year age-standardized net survival for esophageal cancer patients falls short of expectations.Early detection and accurate diagnosis are critical strategies for improving the treatment outcomes of esophageal cancer.While advancements in endoscopic technology have been significant,there seems to be an excessive emphasis on the latest high-end endoscopic devices and various endoscopic resection techniques.Therefore,it is imperative to redirect focus towards proactive early detection strategies for esophageal cancer,investigate the most cost-effective screening methods suitable for different regions,and persistently explore practical solutions to improve the five-year survival rate of patients with esophageal cancer.
基金Supported by Development Program of Shaanxi Province,No.2021SF-221.
文摘BACKGROUND Gastric cancer is a common malignant tumor of the digestive tract,and endosco-pic submucosal dissection(ESD)is the preferred treatment for early-stage gastric cancer.The analysis of the epidemiological characteristics of gastric mucosal tumors with different differentiation degrees and the influencing factors of long-term ESD efficacy may have certain significance for revealing the development of gastric cancer and ESD.AIM To analyze the features of gastric mucosal tumors at different differentiation levels,and to explore the prognostic factors of ESD.METHODS We retrospectively studied 301 lesions in 285 patients at The Second Affiliated Hospital of Xi'an Jiaotong University from 2014 to 2021,according to the latest Japanese guidelines(sixth edition),and divided them into low-grade intrae-pithelial neoplasia(LGIN),high-grade intraepithelial neoplasia(HGIN),and computed tomography at 3,6 and 12 months after ESD.We compared clinicopathologic characteristics,ESD efficacy,and complications with different degrees of differentiation,and analyzed the related factors associated with ESD.RESULTS HGIN and differentiated carcinoma patients were significantly older compared with LGIN patients(P<0.001)and accounted for more 0-IIc(P<0.001),atrophic gastritis was common(P<0.001),and irregular microvascular patterns(IMVPs)and demarcation lines(DLs)were more obvious(P<0.001).There was more infiltration in the undifferentiated carcinoma tissue(P<0.001),more abnormal folds and poorer mucosal peristalsis(P<0.001),and more obvious IMVPs,irregular microsurface patterns and DLs(P<0.05)than in the LGIN and HGIN tissues.The disease-free survival rates at 2,5,and 8 years after ESD were 95.0%,90.1%,and 86.9%,respectively.Undifferen-tiated lesions(HR 5.066),white moss(HR 7.187),incomplete resection(HR 3.658),and multiple primary cancers(HR 2.462)were significantly associated with poor prognosis.CONCLUSION Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics,which are closely related to the safety and efficacy of ESD.