Human rights merit global attention in the current era of globalization. The realization and protectionof human rights is an important part of the process of global governance. Meanwhile, global governance plays a dou...Human rights merit global attention in the current era of globalization. The realization and protectionof human rights is an important part of the process of global governance. Meanwhile, global governance plays a double role in the protection and development of human rights. On the one hand, global governance and hu- man rights have a lot in common, both calling for democracy under the rule of law and protection of citizen rights. On the other hand, to varying degrees global governance weakens the au- thoritv of sovereien states.展开更多
Pollen development is a,pre-requisite for sexual reproduction of angiosperms, during which various cellular activities are involved. Pollen development accompanies dynamic remodeling of vacuoles through fission and fu...Pollen development is a,pre-requisite for sexual reproduction of angiosperms, during which various cellular activities are involved. Pollen development accompanies dynamic remodeling of vacuoles through fission and fusion, disruption of which often compromises pollen viability. We previously reported that the Y subunit of adaptor protein 1 （AP1G） mediates synergid degeneration during pollen tube reception. Here, we demonstrate that AP1G is essential for pollen development. AP1G loss-of-function resulted in male gametophytic lethality due to defective pollen development. By ultrastructural analysis and fluorescence labeling, we demonstrate that AP1G loss-of-function compromised dynamic vacuolar remodeling during pollen development and impaired vacuolar acidification of pollen. Results presented here support a key role of vacuoles in gametophytic pollen development.展开更多
The absence or inadequacy of critical thinking is one of the prevalent problems in English teaching and learning in China, which gives rise to various problems in learners’ writing: digression from the topic, unorigi...The absence or inadequacy of critical thinking is one of the prevalent problems in English teaching and learning in China, which gives rise to various problems in learners’ writing: digression from the topic, unoriginal or uncreative ideas, loose logic, logical fallacies, and lack of real content. Under such circumstances, the present paper proposes the “teaching-learning-assessing-testing Four in One” flipped classroom mode in Educational Informatization 2.0 Background to develop learners’ critical thinking ability relying on technical support provided by the researcher’s school and the mode is then applied in English writing course. The application of the mode has achieved some effects. It is applauded by learners and may thus have some implications for the development of learners’ critical thinking ability in writing courses.展开更多
Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially ...Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially during the critical developmental period.There is a strong interplay between the viral infection as a trigger and a result of ASD.We aim to highlight the mutual relationship between autism and viruses.We performed a thorough literature review and included 158 research in this review.Most of the literature agreed on the possible effects of the viral infection during the critical period of development on the risk of developing autism,especially for specific viral infections such as Rubella,Cytomegalovirus,Herpes Simplex virus,Varicella Zoster Virus,Influenza virus,Zika virus,and severe acute respiratory syndrome coronavirus 2.Viral infection directly infects the brain,triggers immune activation,induces epigenetic changes,and raises the risks of having a child with autism.At the same time,there is some evidence of increased risk of infection,including viral infections in children with autism,due to lots of factors.There is an increased risk of developing autism with a specific viral infection during the early developmental period and an increased risk of viral infections in children with autism.In addition,children with autism are at increased risk of infection,including viruses.Every effort should be made to prevent maternal and early-life infections and reduce the risk of autism.Immune modulation of children with autism should be considered to reduce the risk of infection.展开更多
文摘Human rights merit global attention in the current era of globalization. The realization and protectionof human rights is an important part of the process of global governance. Meanwhile, global governance plays a double role in the protection and development of human rights. On the one hand, global governance and hu- man rights have a lot in common, both calling for democracy under the rule of law and protection of citizen rights. On the other hand, to varying degrees global governance weakens the au- thoritv of sovereien states.
基金supported by Major Research Plan(2013CB945102)from the Ministry of Science,Technology of ChinaNational Natural Science Foundation of China(31625003 and 31471304 to Y.Z.)partially supported by Tai-Shan Scholar Program by Shandong Provincial Government
文摘Pollen development is a,pre-requisite for sexual reproduction of angiosperms, during which various cellular activities are involved. Pollen development accompanies dynamic remodeling of vacuoles through fission and fusion, disruption of which often compromises pollen viability. We previously reported that the Y subunit of adaptor protein 1 （AP1G） mediates synergid degeneration during pollen tube reception. Here, we demonstrate that AP1G is essential for pollen development. AP1G loss-of-function resulted in male gametophytic lethality due to defective pollen development. By ultrastructural analysis and fluorescence labeling, we demonstrate that AP1G loss-of-function compromised dynamic vacuolar remodeling during pollen development and impaired vacuolar acidification of pollen. Results presented here support a key role of vacuoles in gametophytic pollen development.
文摘The absence or inadequacy of critical thinking is one of the prevalent problems in English teaching and learning in China, which gives rise to various problems in learners’ writing: digression from the topic, unoriginal or uncreative ideas, loose logic, logical fallacies, and lack of real content. Under such circumstances, the present paper proposes the “teaching-learning-assessing-testing Four in One” flipped classroom mode in Educational Informatization 2.0 Background to develop learners’ critical thinking ability relying on technical support provided by the researcher’s school and the mode is then applied in English writing course. The application of the mode has achieved some effects. It is applauded by learners and may thus have some implications for the development of learners’ critical thinking ability in writing courses.
文摘Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially during the critical developmental period.There is a strong interplay between the viral infection as a trigger and a result of ASD.We aim to highlight the mutual relationship between autism and viruses.We performed a thorough literature review and included 158 research in this review.Most of the literature agreed on the possible effects of the viral infection during the critical period of development on the risk of developing autism,especially for specific viral infections such as Rubella,Cytomegalovirus,Herpes Simplex virus,Varicella Zoster Virus,Influenza virus,Zika virus,and severe acute respiratory syndrome coronavirus 2.Viral infection directly infects the brain,triggers immune activation,induces epigenetic changes,and raises the risks of having a child with autism.At the same time,there is some evidence of increased risk of infection,including viral infections in children with autism,due to lots of factors.There is an increased risk of developing autism with a specific viral infection during the early developmental period and an increased risk of viral infections in children with autism.In addition,children with autism are at increased risk of infection,including viruses.Every effort should be made to prevent maternal and early-life infections and reduce the risk of autism.Immune modulation of children with autism should be considered to reduce the risk of infection.
