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树突状细胞经cross-dressing递呈抗原在肿瘤免疫中的应用
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作者 卢国鹏 唐海鹏 王梦川(指导) 《中国免疫学杂志》 CAS CSCD 北大核心 2023年第9期1970-1974,共5页
cross-dressing是树突状细胞(DC)区别于交叉递呈和直接递呈的第三种抗原递呈方式,其优势在于DC捕获细胞抗原肽-MHCⅠ类分子复合物后,无须经过加工处理而直接递呈给效应T细胞。近十年来,cross-dressing在肿瘤免疫领域的研究取得了一些成... cross-dressing是树突状细胞(DC)区别于交叉递呈和直接递呈的第三种抗原递呈方式,其优势在于DC捕获细胞抗原肽-MHCⅠ类分子复合物后,无须经过加工处理而直接递呈给效应T细胞。近十年来,cross-dressing在肿瘤免疫领域的研究取得了一些成果,学者们利用小鼠和人源性细胞模型证实cross-dressing存在于不同肿瘤抗原识别和免疫应答过程,初步阐明了cross-dressing的具体途径和DC分子表型,并研究了cross-dressing与交叉递呈的关系。本文就上述问题进行了综述。 展开更多
关键词 树突状细胞 cross-dressing 肿瘤免疫应答
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Prediction of mechanical properties for deep drawing steel by deep learning 被引量:1
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作者 Gang Xu Jinshan He +2 位作者 Zhimin Lü Min Li Jinwu Xu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2023年第1期156-165,共10页
At present,iron and steel enterprises mainly use“after spot test ward”to control final product quality.However,it is impossible to realize on-line quality predetermining for all products by this traditional approach... At present,iron and steel enterprises mainly use“after spot test ward”to control final product quality.However,it is impossible to realize on-line quality predetermining for all products by this traditional approach,hence claims and returns often occur,resulting in major eco-nomic losses of enterprises.In order to realize the on-line quality predetermining for steel products during manufacturing process,the predic-tion models of mechanical properties based on deep learning have been proposed in this work.First,the mechanical properties of deep drawing steels were predicted by using LSTM(long short team memory),GRU(gated recurrent unit)network,and GPR(Gaussian process regression)model,and prediction accuracy and learning efficiency for different models were also discussed.Then,on-line re-learning methods for transfer learning models and model parameters were proposed.The experimental results show that not only the prediction accuracy of optimized trans-fer learning models has been improved,but also predetermining time was shortened to meet real time requirements of on-line property prede-termining.The industrial production data of interstitial-free(IF)steel was used to demonstrate that R2 value of GRU model in training stage reaches more than 0.99,and R2 value in testing stage is more than 0.96. 展开更多
关键词 machine learning recurrent natural network transfer learning on-line prediction deep drawing steel mechanical properties
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Tianmen textile machinery:Independently developed the drawing frame equipment
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《China Textile》 2023年第3期68-68,共1页
Hubei Tianmen Textile Machinery Co.,Ltd.is a well-known enterprise and key high-tech enterprise in China textile industry.The company's leading product,drawing frame,has completely independent intellectual propert... Hubei Tianmen Textile Machinery Co.,Ltd.is a well-known enterprise and key high-tech enterprise in China textile industry.The company's leading product,drawing frame,has completely independent intellectual property rights,among which TM 11 is well received by users and has a high market share in China. 展开更多
关键词 INDEPENDENT drawing Tian
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Research on the Reform of the Course“Reading of Concrete Structure Plan and Construction Drawings”Under the Background of“Promoting Teaching and Learning Through Competitions”
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作者 Guixiang Yu Xiaolong Tan 《Journal of Architectural Research and Development》 2023年第4期32-38,共7页
The inherent teaching approach can no longer meet the demands of society.In this paper,current issues within the teaching landscape of architectural engineering technology in higher vocational colleges as well as the ... The inherent teaching approach can no longer meet the demands of society.In this paper,current issues within the teaching landscape of architectural engineering technology in higher vocational colleges as well as the policies and teaching demands that formed the basis of this model were analyzed.The study shows the importance of the implementation of the teaching model“promoting teaching and learning through competitions.”This model puts emphasis on the curriculum and teaching resources,while also integrating the teaching process and evaluation with competition.These efforts aim to drive education reform in order to better align with the objectives of vocational education personnel training,while also acting as a reference for similar courses. 展开更多
关键词 Promoting teaching through competitions Promoting learning through competitions Reading of concrete structure plan method construction drawings Course reform
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基于Visio Drawing Control控件的图形化潮流计算软件开发 被引量:7
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作者 张鸿博 蔡晓峰 《华北水利水电学院学报》 2009年第1期70-72,共3页
针对VC,Delphi等工具开发电力系统分析计算软件图形可视化的缺陷,提出并研究了一种基于VisioDrawing Control图形控件,利用VC进行二次开发的图形化电力系统潮流计算软件开发的技术,研究了基于该控件的图形化建模方法及电网拓扑结构的自... 针对VC,Delphi等工具开发电力系统分析计算软件图形可视化的缺陷,提出并研究了一种基于VisioDrawing Control图形控件,利用VC进行二次开发的图形化电力系统潮流计算软件开发的技术,研究了基于该控件的图形化建模方法及电网拓扑结构的自动识别,开发了实用的电力系统图形化潮流计算软件.实践表明,基于Visio Drawing Control的二次开发技术为图形化电力系统潮流计算软件的开发提供了新的有效的途径. 展开更多
关键词 VISIO drawing CONTROL 二次开发 图形化 潮流计算
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工程图协同审议与存档管理系统VHDrawings的设计与实现 被引量:3
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作者 许列飞 赵宏俊 +1 位作者 匡海峰 蔡士杰 《计算机工程与应用》 CSCD 北大核心 2003年第23期210-213,共4页
工程设计单位的审图工作是一个需要多人参与、多次往复的过程。用传统的方法传递设计图与修改意见,速度慢且易出错,限制了工程设计单位工作效率的提高。该文介绍了一个计算机辅助的工程图协同审议与存档管理系统VHDrawings的设计与实现... 工程设计单位的审图工作是一个需要多人参与、多次往复的过程。用传统的方法传递设计图与修改意见,速度慢且易出错,限制了工程设计单位工作效率的提高。该文介绍了一个计算机辅助的工程图协同审议与存档管理系统VHDrawings的设计与实现。着重讨论了协同审图工作流的管理以及工程图自动识别技术在图档管理中的应用。为设计单位提高工作效率、优化管理流程提供了一种参考。 展开更多
关键词 计算机支持协同工作(CSCW) 工作流管理 图档管理 异步交互 同步交互
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eDrawings在《工程制图》多媒体课件中的应用 被引量:5
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作者 陈光霞 《现代机械》 2010年第1期53-54,75,共3页
分析了在《工程制图》多媒体课件中使用AutoCAD和SolidWorks两种软件时存在的不足,阐述了eDrawings在课件中的应用优势。论述了CAD二维图形和SolidWorks三维模型转换成eDrawings文件的方法、常见问题、问题产生的原因和解决方法。给出... 分析了在《工程制图》多媒体课件中使用AutoCAD和SolidWorks两种软件时存在的不足,阐述了eDrawings在课件中的应用优势。论述了CAD二维图形和SolidWorks三维模型转换成eDrawings文件的方法、常见问题、问题产生的原因和解决方法。给出了应用实例。 展开更多
关键词 工程制图 EdrawingS AUTOCAD SOLIDWORKS 多媒体课件
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海外项目shop drawing的理解 被引量:2
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作者 杨艺冠 潘晓军 《中国港湾建设》 2012年第5期76-79,共4页
通过对海外项目shop drawing(细化图)的理解,阐述了shop drawing的定义以及绘制shop drawing过程中需要注意的问题。通过实例分析,为同类型国际港口工程中细化设计提供参考和借鉴。
关键词 海外项目 SHOP drawing 理解
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运用Pro/E Drawing参数设置功能生成压缩机零部件标准工程图
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作者 蔡晓君 刘湘晨 张建军 《压缩机技术》 2010年第4期16-18,21,共4页
作为机械三维参数化设计软件的佼佼者,Pro/E以其卓越的设计、分析和运动仿真等功能为企业新产品的开发带来了巨大的效益,但对企业来说新产品开发的最终目标是加工与生产。因此进一步开发研究使用Pro/E Drawing模块的各种功能,为企业定... 作为机械三维参数化设计软件的佼佼者,Pro/E以其卓越的设计、分析和运动仿真等功能为企业新产品的开发带来了巨大的效益,但对企业来说新产品开发的最终目标是加工与生产。因此进一步开发研究使用Pro/E Drawing模块的各种功能,为企业定制出符合国标要求的零部件工程图,具有巨大的应用前景。 展开更多
关键词 参数 标准 工程图
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EFFECTS OF SPECIFIED BLANK SIZE ON BODY WRINKLING DURING HYDRODYNAMIC DEEP DRAWING OF TAPERED RECTANGULAR BOX 被引量:21
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作者 L. H. Lang, D. C. Kang, S. H. Zhang, Z. R. Wang, S. J. Yuan, K. B. Nielsen and J. Dancket 1) Department of Materials Engineering, Harbin Institute of Technology, Harbin 150001, China 2) Aalberg University, Denmark 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2000年第2期476-480,共5页
In this paper, the forming features of tapered rectangular box during hydrodynamic deep drawing are studied by means of FEM.The effect rules of square blank corner corner amount on body wrinkling are recognized and co... In this paper, the forming features of tapered rectangular box during hydrodynamic deep drawing are studied by means of FEM.The effect rules of square blank corner corner amount on body wrinkling are recognized and corresponding methods are discussed. At last, the results of FEM are verified by experi- ment. 展开更多
关键词 SHEET metal FORMING HYDRODYNAMIC deep drawing FEM
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A LOOP DRAWBEAD RESTRAINING FORCE MODEL IN SHEET METAL DEEP DRAWING PROCESS 被引量:11
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作者 Y.J. Luo, S.P. Li, J.F. Zheng, D.N. He, Y.Q. Zhang, J.L. Cheng and J. Y. Jiang 1)National Mold & Die CAD Engineering Research Center, Shanghai 200030, China 2)Shanghai Volkswagen Automotive Company Ltd.(SVM), Shanghai 201805, China 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2001年第5期380-386,共7页
In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead fo... In sheet metal forming, drawbeads are often used to control uneven material flow which may cause defects such as wrinkles, fracture, surface distortion and springback. Appropriate setting and adjusting the drawbead force is one of the most important pa- rameters in sheet metal forming process control. This paper derives the model of loop drawbead restraining force (DBRF) using plastic forming theory, and gives the min imum blankholding force. Experiments are carried out to verify the proposed DBRF model. The good agreement between the calculated values and experiments data justi- fies the proposed loop drawbead restraining force model. 展开更多
关键词 drawbead restraining force SHEET metal DEEP drawing
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RESEARCH ON THE EVALUATION METHOD OF FRICTION AND LUBRICATION IN DEEP DRAWING 被引量:13
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作者 D. N. He, X. F. Yin, H. Z. Thao, D. L*, X. Y. Ruan, J. L. Cheng and J. Y. Jiang 1) Shanghai Jiao Tong University, National Die & Mold CAD E. R. C, Shanghai 200030, China 2) Shanghai Vopkswagen Automotive Company Ltd., Shanghai 201805, China Manuscript re 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2000年第2期439-445,共7页
The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other... The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other plastic process. The common test methods in laboratories are analyzed. It shows that though all those test methods can test the friction coefficient, the probe test method is most suitable for the research of friction and lubrication and the process in deep drawing, for this method is identical with the actual work condition either from the test principle or deformation status of the blank. Last the successful application in the deep drawing simulator newly developed the the probe method are intro- duced in detail. 展开更多
关键词 deep drawing PROBE test METHOD FRICTION and LUBRICATION evaluation METHOD
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High-Performance Solid-State Supercapacitors Fabricated by Pencil Drawing and Polypyrrole Depositing on Paper Substrate 被引量:4
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作者 Jiayou Tao Wenzhen Ma +4 位作者 Nishuang Liu Xiaoliang Ren Yuling Shi Jun Su Yihua Gao 《Nano-Micro Letters》 SCIE EI CAS 2015年第3期276-281,共6页
A solid-state powerful supercapacitor(SC) is fabricated with a substrate of Xerox paper. Its current collector based on a foldable electronic circuit is developed by simply pencil drawing. Thin graphite sheets on pape... A solid-state powerful supercapacitor(SC) is fabricated with a substrate of Xerox paper. Its current collector based on a foldable electronic circuit is developed by simply pencil drawing. Thin graphite sheets on paper provide effective channels for electron transmission with a low resistance of 95 X sq-1. The conductive organic material of polypyrrole coated on thin graphite sheets acts as the electrode material of the device. The as-fabricated SC exhibits a high specific capacitance of 52.9 F cm-3at a scan rate of 1 m V s-1. An energy storage unit fabricated by three full-charged series SCs can drive a commercial light-emitting diode robustly. This work demonstrated a simple, versatile and costeffective method for paper-based devices. 展开更多
关键词 SUPERCAPACITOR PAPER Pencil drawing POLYPYRROLE
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谈国际港口工程中Shop Drawing的绘制 被引量:2
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作者 潘晓军 《工程建设与设计》 2011年第11期130-133,共4页
通过对巴基斯坦卡拉奇卡西姆港已实施的国际集装箱码头施工总承包项目现场施工图ShopDrawing的绘制,总结了绘制ShopDrawing的前提条件以及在图纸绘制过程中需要注意的事项,为同类型国际港口工程中细化设计提供了一些参考和借鉴。
关键词 港口工程 SHOP drawing 绘制
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Phase-Division-Based Dynamic Optimization of Linkages for Drawing Servo Presses 被引量:4
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作者 Zhi-Gang Zhang Li-Ping Wang Yan-Ke Cao 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2017年第6期1426-1437,共12页
Existing linkage-optimization methods are designed for mechanical presses; few can be directly used for servo presses, so development of the servo press is limited. Based on the complementarity of linkage optimization... Existing linkage-optimization methods are designed for mechanical presses; few can be directly used for servo presses, so development of the servo press is limited. Based on the complementarity of linkage optimization and motion planning, a phase-division-based linkage-optimization model for a drawing servo press is established. Considering the motion-planning principles of a drawing servo press, and taking account of work rating and efficiency, the constraints of the optimization model are constructed. Linkage is optimized in two modes: use of either constant eccentric speed or constant slide speed in the work segments. The performances of optimized linkages are compared with those of a mature linkage SL4-2000A,which is optimized by a traditional method. The results show that the work rating of a drawing servo press equipped with linkages optimized by this new method improved and the root-mean-square torque of the servo motors is reduced by more than 10%. This research provides a promising method for designing energy-saving drawing servo presses with high work ratings. 展开更多
关键词 drawing servo press Linkage optimization Phase-division Motion planning
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Theoretical description of drawing body shape in an inclined seam with longwall top coal caving mining 被引量:6
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作者 Jiachen Wang Weijie Wei Jinwang Zhang 《International Journal of Coal Science & Technology》 EI 2020年第1期182-195,共14页
Understanding the characteristics of drawing body shape is essential for optimization of drawing parameters in longwall top coal caving mining.In this study,both physical experiments and theoretical analysis are emplo... Understanding the characteristics of drawing body shape is essential for optimization of drawing parameters in longwall top coal caving mining.In this study,both physical experiments and theoretical analysis are employed to investigate these characteristics and derive a theoretical equation for the drawing body shape along the working face in an inclined seam.By analyzing the initial positions of drawn marked particles,the characteristics of the drawing body shape for different seam dip angles are obtained.It is shown that the drawing body of the top coal exhibits a shape-difference and volume-symmetry characteristic,on taking a vertical line through the center of support opening as the axis of symmetry,the shapes of the drawing body on the two sides of this axis are clearly different,but their volumes are equal.By establishing theoretical models of the drawing body in the initial drawing stage and the normal drawing stage,a theoretical equation for the drawing body in an inclined seam is proposed,which can accurately describe the characteristics of the drawing body shape.The shape characteristics and volume symmetry of the drawing body are further analyzed by comparing the results of theoretical calculations and numerical simulations.It is shown that one side of the drawing body is divided into two parts by an inflection point,with the lower part being a variation development area.This variation development area increases gradually with increasing seam dip angle,resulting in an asymmetry of the drawing body shape.However,the volume symmetry coefficient fluctuates around 1 for all values of the seam dip angle variation,and the volumes of the drawing body on the two sides are more or less equal as the variation development volume is more or less equal to the cut volume.Both theoretical calculations and numerical simulations confirm that the drawing body of the top coal exhibits the shape-difference and volume-symmetry characteristic. 展开更多
关键词 Longwall top coal caving mining Inclined seam Top coal drawing body shape Equation for drawing body
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Effect of Friction Coefficient on Deep Drawing of 6A16 Aluminum Alloy for Automobile Body 被引量:2
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作者 刘钊扬 熊柏青 +4 位作者 LI Xiwu YAN Lizhen LI Zhihui ZHANG Yongan LIU Hongwei 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2020年第1期208-214,共7页
Based on the ABAQUS/Explicit finite element method,the forming force changing trend of deep drawing test for 6A16 aluminum alloy plate after pre-aging and storage at room temperature for one month was simulated under ... Based on the ABAQUS/Explicit finite element method,the forming force changing trend of deep drawing test for 6A16 aluminum alloy plate after pre-aging and storage at room temperature for one month was simulated under friction coefficient ranging from 0 to 0.22.The lubricants selected for the tests were mechanical oil,butter and dry film lubricant,and the friction coefficient of these lubricants were 0.05,0.10 and 0.15,respectively.Microstructural evolution of 6 A16 aluminum alloy plate during drawing forming was investigated by OM,SEM and EBSD.The results showed that,with the increase of friction coefficient,the stress,strain and deformation degree in deformation zone increased,while the grain size in deformation zone decreased.Thus,the hardness of the cup-typed component increased with the increase of friction coefficient.Butter-lubricated cups had the highest tensile strength and yield strength after paint-bake cycle.The combination of simulation results and microstructure analysis of 6A16 aluminum alloy plate after drawing forming indicates that the appropriate lubricant is butter. 展开更多
关键词 FINITE element method 6A16 aluminum alloys deep drawing test FRICTION COEFFICIENT
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SURFACE INTEGRAL OF THREE-DIMENSIONAL VELOCITY FIELD FOR SQUARE BAR DRAWING THROUGH CONICAL DIE 被引量:2
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作者 Zhao, DW Guo, CW +1 位作者 Liu, XH Fang, YK 《中国有色金属学会会刊:英文版》 CSCD 1996年第3期131-135,共5页
SURFACEINTEGRALOFTHREE-DIMENSIONALVELOCITYFIELDFORSQUAREBARDRAWINGTHROUGHCONICALDIE¥ZhaoDewen;GuoChangwu;Liu... SURFACEINTEGRALOFTHREE-DIMENSIONALVELOCITYFIELDFORSQUAREBARDRAWINGTHROUGHCONICALDIE¥ZhaoDewen;GuoChangwu;LiuXianghua(RollingT... 展开更多
关键词 SQUARE BAR drawing three dimensional VELOCITY FIELD surface INTEGRAL
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Prediction of Eight Earings in Deep Drawing of 5754O Aluminum Alloy Sheet 被引量:1
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作者 Haibo Wang Mingliang Men +2 位作者 Yu Yan Min Wan Qiang Li 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2019年第5期136-144,共9页
Earings appear easily during deep drawing of cylindrical parts owing to the anisotropic properties of materials.However,current methods cannot fully utilize the mechanical properties of material,and the number of eari... Earings appear easily during deep drawing of cylindrical parts owing to the anisotropic properties of materials.However,current methods cannot fully utilize the mechanical properties of material,and the number of earings obtained differ with the simulation methods.In order to predict the eight-earing problem in the cylindrical deep drawing of 5754O aluminum alloy sheet,a new method of combining the yield stress and anisotropy index(r-value)to solve the parameters of the Hil 148 yield function is proposed.The general formula for the yield stress and r-value in any direction is presented.Taking a 5754O aluminum alloy sheet as an example in this study,the deformation area in deep drawing is divided into several equal sectorial regions based on the anisotropy.The parameters of the Hill48 yield function are solved based on the yield stress and r-value simultaneously for the corresponding deformation area.Finite element simulations of deep drawing based on new and existing methods are carried out for comparison with experimental results.This study provides a convenient and reliable way to predict the formation of eight earings in the deep drawing process,which is expected to be useful in industrial applications.The results of this study lay the foundation for the optimization of the cylindrical deep drawing process,including the optimization of the blank shape to eliminate earing defects on the final product,which is of great importance in the actual production process. 展开更多
关键词 ANISOTROPY Deep drawing YIELD function FINITE element simulation
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Integral as a Function of the Upper Limit to Solve Axial Symmetrical Rod Drawing and Extrusion 被引量:1
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作者 赵德文 赵志业 张强 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 1990年第4期282-288,共7页
A kinematically admissible velocity field which is different from Avitzur’s has been proposed for axialsymmetrical rod drawing and extrusion.An upper-bound analytical solution in cylindrical coordinates hasbeen obtai... A kinematically admissible velocity field which is different from Avitzur’s has been proposed for axialsymmetrical rod drawing and extrusion.An upper-bound analytical solution in cylindrical coordinates hasbeen obtained without any mathematical simplification in this paper. 展开更多
关键词 drawing EXTRUSION velocity field upper-bound power
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