Despite growing research for residential crowding effects on housing market and public health perspectives, relatively little attention has been paid to explore and model spatial patterns of residential crowding over ...Despite growing research for residential crowding effects on housing market and public health perspectives, relatively little attention has been paid to explore and model spatial patterns of residential crowding over space. This paper focuses upon analyzing the spatial relationships between residential crowding and socio-demographic variables in Alexandria neighborhoods, Egypt. Global and local geo-statistical techniques were employed within GIS-based platform to identify spatial?variations of residential crowding determinates. The global ordinary least squares (OLS) model?assumes homogeneity of relationships between response variable and explanatory variables?across the study area. Consequently, it fails to account for heterogeneity of spatial relationships. Local model known as a geographically weighted regression (GWR) was also employed using the same?response variable and explanatory variables to capture spatial non-stationary of residential?crowding. A comparison of the outputs of both models indicated that OLS explained 74 percent of?residential crowding variations while GWR model explained 79 percent. The GWR improvedstrength of the model and provided a better goodness of fit than OLS. In addition, the findings of this analysis revealed that residential crowding was significantly associated with different structural measures particularly social characteristics of household such as higher education and illiteracy. Similarly, population size of neighborhood and number of dwelling rooms were found to have direct impacts on residential crowding rate. The spatial relationship of these measures distinctly varies over the study area.展开更多
Overcrowding has become a non negligible issue for metros in China.This paper analyzes the impact of crowding in metro carriages on people’s travel behaviors based on the stated preference survey data from college st...Overcrowding has become a non negligible issue for metros in China.This paper analyzes the impact of crowding in metro carriages on people’s travel behaviors based on the stated preference survey data from college students and full time workers in Guangzhou.The data were analyzed by using the constant value per trip model and the travel time multiplier model with the multinomial logit modeling technique.Results show that there is a significant impact of crowding in metro carriages on passengers’welfare.The relationship between the disutility of crowding and the standee density is not linear.Commuters do not care much about crowding in the metro,whereas non commuters and college students pay special attention to crowding in metro carriages,especially when the carriage is crowded.This paper presents new findings of the impact of demographic characteristics on the evaluation of crowding in metro carriages in developing countries.展开更多
Intraspecific competition at the larval stage is an important ecological factor affecting life-history,adaptation and evolutionary trajectory in holometabolous insects.However,the molecular pathways underpinning these...Intraspecific competition at the larval stage is an important ecological factor affecting life-history,adaptation and evolutionary trajectory in holometabolous insects.However,the molecular pathways underpinning these ecological processes are poorly characterized.We reared Drosophila melanogaster at three egg densities(5,60,and 300 eggs/mL)and sequenced the transcriptomes of pooled third-instar larvae.We also examined emergence time,egg-to-adult viability,adult mass,and adult sex-ratio at each density.Medium crowding had minor detrimental effects on adult phenotypes compared to low density and yielded 24 differentially expressed genes(DEGs),including several chitinase enzymes.In contrast,high crowding had substantial detrimental effects on adult phenotypes and yielded 2107 DEGs.Among these,upregulated gene sets were enriched in sugar,steroid and amino acid metabolism as well as DNA replication pathways,whereas downregulated gene sets were enriched in ABC transporters,taurine,Toll/Imd signaling,and P450 xenobiotics metabolism pathways.Overall,our findings show that larval crowding has a large consistent effect on several molecular pathways(i.e.,core responses)with few pathways displaying density-specific regulation(i.e.,idiosyncratic responses).This provides important insights into how holometabolous insects respond to intraspecific competition during development.展开更多
The dynamic pricing environment offers flexibility to the consumers to reschedule their switching appliances.Though the dynamic pricing environment results in several benefits to the utilities and consumers,it also po...The dynamic pricing environment offers flexibility to the consumers to reschedule their switching appliances.Though the dynamic pricing environment results in several benefits to the utilities and consumers,it also poses some challenges.The crowding among residential customers is one of such challenges.The scheduling of loads at low-cost intervals causes crowding among residential customers,which leads to a fall in voltage of the distribution system below its prescribed limits.In order to prevent crowding phenomena,this paper proposes a priority-based demand response program for local energy communities.In the program,past contributions made by residential houses and demand are considered as essential parameters while calculating the priority factor.The non-linear programming(NLP)model proposed in this study seeks to reschedule loads at low-cost intervals to alleviate crowding phenomena.Since the NLP model does not guarantee global optima due to its non-convex nature,a second-order cone programming model is proposed,which captures power flow characteristics and guarantees global optimum.The proposed formulation is solved using General Algebraic Modeling System(GAMS)software and is tested on a 12.66 kV IEEE 33-bus distribution system,which demonstrates its applicability and efficacy.展开更多
Crowd counting is a promising hotspot of computer vision involving crowd intelligence analysis,achieving tremendous success recently with the development of deep learning.However,there have been stillmany challenges i...Crowd counting is a promising hotspot of computer vision involving crowd intelligence analysis,achieving tremendous success recently with the development of deep learning.However,there have been stillmany challenges including crowd multi-scale variations and high network complexity,etc.To tackle these issues,a lightweight Resconnection multi-branch network(LRMBNet)for highly accurate crowd counting and localization is proposed.Specifically,using improved ShuffleNet V2 as the backbone,a lightweight shallow extractor has been designed by employing the channel compression mechanism to reduce enormously the number of network parameters.A light multi-branch structure with different expansion rate convolutions is demonstrated to extract multi-scale features and enlarged receptive fields,where the information transmission and fusion of diverse scale features is enhanced via residual concatenation.In addition,a compound loss function is introduced for training themethod to improve global context information correlation.The proposed method is evaluated on the SHHA,SHHB,UCF-QNRF and UCF_CC_50 public datasets.The accuracy is better than those of many advanced approaches,while the number of parameters is smaller.The experimental results show that the proposed method achieves a good tradeoff between the complexity and accuracy of crowd counting,indicating a lightweight and high-precision method for crowd counting.展开更多
Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, manyresearchers proposed game theoreticmodels to avoid and remove obstacles for crowd evacuation. Game theoret...Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, manyresearchers proposed game theoreticmodels to avoid and remove obstacles for crowd evacuation. Game theoreticalmodels aim to study and analyze the strategic behaviors of individuals within a crowd and their interactionsduring the evacuation. Game theoretical models have some limitations in the context of crowd evacuation. Thesemodels consider a group of individuals as homogeneous objects with the same goals, involve complex mathematicalformulation, and cannot model real-world scenarios such as panic, environmental information, crowds that movedynamically, etc. The proposed work presents a game theoretic model integrating an agent-based model to removethe obstacles from exits. The proposed model considered the parameters named: (1) obstacle size, length, andwidth, (2) removal time, (3) evacuation time, (4) crowd density, (5) obstacle identification, and (6) route selection.The proposed work conducts various experiments considering different conditions, such as obstacle types, obstacleremoval, and several obstacles. Evaluation results show the proposed model’s effectiveness compared with existingliterature in reducing the overall evacuation time, cell selection, and obstacle removal. The study is potentially usefulfor public safety situations such as emergency evacuations during disasters and calamities.展开更多
In a crowd density estimation dataset,the annotation of crowd locations is an extremely laborious task,and they are not taken into the evaluation metrics.In this paper,we aim to reduce the annotation cost of crowd dat...In a crowd density estimation dataset,the annotation of crowd locations is an extremely laborious task,and they are not taken into the evaluation metrics.In this paper,we aim to reduce the annotation cost of crowd datasets,and propose a crowd density estimation method based on weakly-supervised learning,in the absence of crowd position supervision information,which directly reduces the number of crowds by using the number of pedestrians in the image as the supervised information.For this purpose,we design a new training method,which exploits the correlation between global and local image features by incremental learning to train the network.Specifically,we design a parent-child network(PC-Net)focusing on the global and local image respectively,and propose a linear feature calibration structure to train the PC-Net simultaneously,and the child network learns feature transfer factors and feature bias weights,and uses the transfer factors and bias weights to linearly feature calibrate the features extracted from the Parent network,to improve the convergence of the network by using local features hidden in the crowd images.In addition,we use the pyramid vision transformer as the backbone of the PC-Net to extract crowd features at different levels,and design a global-local feature loss function(L2).We combine it with a crowd counting loss(LC)to enhance the sensitivity of the network to crowd features during the training process,which effectively improves the accuracy of crowd density estimation.The experimental results show that the PC-Net significantly reduces the gap between fullysupervised and weakly-supervised crowd density estimation,and outperforms the comparison methods on five datasets of Shanghai Tech Part A,ShanghaiTech Part B,UCF_CC_50,UCF_QNRF and JHU-CROWD++.展开更多
Estimation of crowd count is becoming crucial nowadays,as it can help in security surveillance,crowd monitoring,and management for different events.It is challenging to determine the approximate crowd size from an ima...Estimation of crowd count is becoming crucial nowadays,as it can help in security surveillance,crowd monitoring,and management for different events.It is challenging to determine the approximate crowd size from an image of the crowd’s density.Therefore in this research study,we proposed a multi-headed convolutional neural network architecture-based model for crowd counting,where we divided our proposed model into two main components:(i)the convolutional neural network,which extracts the feature across the whole image that is given to it as an input,and(ii)the multi-headed layers,which make it easier to evaluate density maps to estimate the number of people in the input image and determine their number in the crowd.We employed the available public benchmark crowd-counting datasets UCF CC 50 and ShanghaiTech parts A and B for model training and testing to validate the model’s performance.To analyze the results,we used two metrics Mean Absolute Error(MAE)and Mean Square Error(MSE),and compared the results of the proposed systems with the state-of-art models of crowd counting.The results show the superiority of the proposed system.展开更多
AIM:To compare superficial and deep vascular properties of optic discs between crowded discs and controls using optical coherence tomography angiography(OCT-A).METHODS:Thirty patients with crowded discs,and 47 control...AIM:To compare superficial and deep vascular properties of optic discs between crowded discs and controls using optical coherence tomography angiography(OCT-A).METHODS:Thirty patients with crowded discs,and 47 control subjects were enrolled in the study.One eye of each individual was included and OCT-A scans of optic discs were obtained in a 4.5×4.5 mm^(2) rectangular area.Radial peripapillary capillary(RPC)density,peripapillary retinal nerve fiber layer(pRNFL)thickness,cup volume,rim area,disc area,cup-to-disc(c/d)area ratio,and vertical c/d ratio were obtained automatically using device software.Automated parapapillary choroidal microvasculature(PPCMv)density was calculated using MATLAB software.When the vertical c/d ratio of the optic disc was absent or small cup,it was considered as a crowded disc.RESULTS:The mean signal strength index of OCT-A images was similar between the crowded discs and control eyes(P=0.740).There was no difference in pRNFL between the two groups(P=0.102).There were no differences in RPC density in whole image(P=0.826)and peripapillary region(P=0.923),but inside disc RPC density was higher in crowded optic discs(P=0.003).The PPCMv density in the inner-hemisuperior region was also lower in crowded discs(P=0.026).The pRNFL thickness was positively correlated with peripapillary RPC density(r=0.498,P<0.001).The inside disc RPC density was negatively correlated with c/d area ratio(r=-0.341,P=0.002).CONCLUSION:The higher inside disc RPC density and lower inner-hemisuperior PPCMv density are found in eyes with crowded optic discs.展开更多
This paper introduces a novel variant of particle swarm optimization that leverages local displacements through attractors for addressing multiobjective optimization problems. The method incorporates a square root dis...This paper introduces a novel variant of particle swarm optimization that leverages local displacements through attractors for addressing multiobjective optimization problems. The method incorporates a square root distance mechanism into the external archives to enhance the diversity. We evaluate the performance of the proposed approach on a set of constrained and unconstrained multiobjective test functions, establishing a benchmark for comparison. In order to gauge its effectiveness relative to established techniques, we conduct a comprehensive comparison with well-known approaches such as SMPSO, NSGA2 and SPEA2. The numerical results demonstrate that our method not only achieves efficiency but also exhibits competitiveness when compared to evolutionary algorithms. Particularly noteworthy is its superior performance in terms of convergence and diversification, surpassing the capabilities of its predecessors.展开更多
GaN-based vertical P-i-N diode with mesa edge terminal structure due to electric field crowding effect, the breakdown voltage of the device is significantly reduced. This work investigates three terminal structures, i...GaN-based vertical P-i-N diode with mesa edge terminal structure due to electric field crowding effect, the breakdown voltage of the device is significantly reduced. This work investigates three terminal structures, including deeply etched, bevel, and stepped-mesas terminal structures, to suppress electric field crowding effects at the device and junction edges. Deeply-etched mesa terminal yields a breakdown voltage of 1205 V, i.e., 89% of the ideal voltage. The bevel-mesa terminal achieves about 89% of the ideal breakdown voltage, while the step-mesa terminal is less effective in mitigating electric field crowding, at about 32% of the ideal voltage. This work can provide an important reference for the design of high-power, high-voltage GaN-based P-i-N power devices, finding a terminal protection structure suitable for GaNPiN diodes to further enhance the breakdown performance of the device and to unleash the full potential of GaN semiconductor materials.展开更多
An extended crowding genetic algorithm (ECGA) is introduced for solvingoptimal pump configuration problem, which was presented by T. Westerlund in 1994. This problem hasbeen found to be non-convex, and the objective f...An extended crowding genetic algorithm (ECGA) is introduced for solvingoptimal pump configuration problem, which was presented by T. Westerlund in 1994. This problem hasbeen found to be non-convex, and the objective function contained several local optima and globaloptimality could not be ensured by all the traditional MINLP optimization method. The concepts ofspecies conserving and composite encoding are introduced to crowding genetic algorithm (CGA) formaintain the diversity of population more effectively and coping with the continuous and/or discretevariables in MINLP problem. The solution of three-levels pump configuration got from DICOPT++software (OA algorithm) is also given. By comparing with the solutions obtained from DICOPT++, ECPmethod, and MIN-MIN method, the ECGA algorithm proved to be very effective in finding the globaloptimal solution of multi-levels pump configuration via using the problem-specific information.展开更多
This paper deals with the global dynamical behaviors of the positive solutions for a parabolic type ratio-dependent predator-prey system with a crowding term in the prey equation, where it is assumed that the coeffici...This paper deals with the global dynamical behaviors of the positive solutions for a parabolic type ratio-dependent predator-prey system with a crowding term in the prey equation, where it is assumed that the coefficient of the functional response is less than the coefficient of the intrinsic growth rates of the prey species. We demonstrated some special dynamical behaviors of the positive solutions of this system which the persistence of the coexistence of two species can be obtained when the crowding region in the prey equation only is designed suitably. Furthermore, we can obtain that under some conditions, the unique positive steady state solution of the system is globally asymptotically stable.展开更多
In this study,juvenile turbot Scophthalmus maximus were vaccinated with attenuated Edwardsiella tarda(EIBAV1)and reared at two different densities,low density(LD),(5.25±0.02)kg m−2,as control group and high densi...In this study,juvenile turbot Scophthalmus maximus were vaccinated with attenuated Edwardsiella tarda(EIBAV1)and reared at two different densities,low density(LD),(5.25±0.02)kg m−2,as control group and high density(HD),(20.53±0.05)kg m−2,as experimental group.Only density was considered as the variable.Five weeks after vaccination,the transcriptomes of spleen and head kidney from the turbot in two groups were analyzed with RNA-Seq technology.A total of 447 million reads were assembled into 41136 genes with an average length of 1274 bp and a N50 size of 2295 bp.A comparison of gene expression between HD and LD groups revealed 1155 differentially expressed genes(DEGs).Enrichment and pathway analysis of the 10 immune-related DEGs showed the centrality of toll-like receptor signaling pathway,cytosolic DNA-sensing pathway and platelet activation in the host immune responses.The 5 overexpressed inflammatory cytokines and 5 downregulated signal-regulated cytokines genes are covered by these immune-related DEGs.It was inferred that cells suffer damage and the immune response is restrained in turbot under crowding stress.展开更多
This paper deals with a Lotka-Volterra predator-prey model with a crowding term in the predator equation.We obtain a critical value λ1^D(Ω0),and demonstrate that the existence of the predator inΩ0 only depends on t...This paper deals with a Lotka-Volterra predator-prey model with a crowding term in the predator equation.We obtain a critical value λ1^D(Ω0),and demonstrate that the existence of the predator inΩ0 only depends on the relationship of the growth rateμof the predator and λ1^D(Ω0),not on the prey.Furthermore,whenμ<λ1^D(Ω0),we obtain the existence and uniqueness of its positive steady state solution,while whenμ≥λ1^D(Ω0),the predator and the prey cannot coexist inΩ0.Our results show that the coexistence of the prey and the predator is sensitive to the size of the crowding regionΩ0,which is different from that of the classical Lotka-Volterra predator-prey model.展开更多
This study analyzes drift phenomena of deterministic crowding and probabilistic crowding by using equivalence class model and expectation proportion equations. It is proved that the replacement errors of deterministic...This study analyzes drift phenomena of deterministic crowding and probabilistic crowding by using equivalence class model and expectation proportion equations. It is proved that the replacement errors of deterministic crowding cause the population converging to a single individual, thus resulting in premature stagnation or losing optional optima. And probabilistic crowding can maintain equilibrium multiple subpopulations as the population size is adequate large. An improved niching method using clustering crowding is proposed. By analyzing topology of fitness landscape using hill valley function and extending the search space for similarity analysis, clustering crowding determines the locality of search space more accurately, thus greatly decreasing replacement errors of crowding. The integration of deterministic and probabilistic replacement increases the capacity of both parallel local hill climbing and maintaining multiple subpopulations. The experimental results optimizing various multimodal functions show that,the performances of clustering crowding, such as the number of effective peaks maintained, average peak ratio and global optimum ratio are uniformly superior to those of the evolutionary algorithms using fitness sharing, simple deterministic crowding and probabilistic crowding.展开更多
This study was undertaken to examine which factors contributed to the correction of crowding in two patients who underwent nonextraction orthodontic treatment. A study model analysis was conducted to determine the eff...This study was undertaken to examine which factors contributed to the correction of crowding in two patients who underwent nonextraction orthodontic treatment. A study model analysis was conducted to determine the effects of the orthodontic treatment for crowding with high canines on crown angulation and dental arch width in two patients. The results showed that the crown angulation was significantly increased, indicating distal tipping in the maxillary dental arch. This tendency was most commonly observed in the premolars among the lateral teeth. With respect to the dental arch width, the largest change was evident in the first molar and first premolar regions in cases 1 and 2, respectively. On the basis of these results, up-righting of mesially tipped lateral teeth and expansion of narrow dental arches could prove to be the keys to the success of space regaining or correction of high canines and mild crowding.展开更多
BACKGROUND:In patients with chest pain who arrive at the emergency department(ED)by ambulance,venous access is frequently established prehospital,and could be utilized to sample blood.Prehospital blood sampling may sa...BACKGROUND:In patients with chest pain who arrive at the emergency department(ED)by ambulance,venous access is frequently established prehospital,and could be utilized to sample blood.Prehospital blood sampling may save time in the diagnostic process.In this study,the association of prehospital blood draw with blood sample arrival times,troponin turnaround times,and ED length of stay(LOS),number of blood sample mix-ups and blood sample quality were assessed.METHODS:The study was conducted from October 1,2019 to February 29,2020.In patients who were transported to the ED with acute chest pain with low suspicion for acute coronary syndrome(ACS),outcomes were compared between cases,in whom prehospital blood draw was performed,and controls,in whom blood was drawn at the ED.Regression analyses were used to assess the association of prehospital blood draw with the time intervals.RESULTS:Prehospital blood draw was performed in 100 patients.In 406 patients,blood draw was performed at the ED.Prehospital blood draw was independently associated with shorter blood sample arrival times,shorter troponin turnaround times and decreased LOS(P<0.001).No differences in the number of blood sample mix-ups and quality were observed(P>0.05).CONCLUSION:For patients with acute chest pain with low suspicion for ACS,prehospital blood sampling is associated with shorter time intervals,while there were no significant differences between the two groups in the validity of the blood samples.展开更多
Overcrowding and cell deformation lead to the shedding of apoptotic and live cells to maintain homeostasis in the epithelium. Recent studies have attempted to explain the effect of extrusion on epithelial homeostasis ...Overcrowding and cell deformation lead to the shedding of apoptotic and live cells to maintain homeostasis in the epithelium. Recent studies have attempted to explain the effect of extrusion on epithelial homeostasis and tumor metastasis, but lack the requisite quantitative models for testing extrusion. Here, we designed a petri dish inversion model to detect the extrusion ability of both normal epithelial cells and epithelial cancer cells. Firstly, we found cell extrusion was observed in both normal epithelial cells (LO2 cells) and cancer cells;in confluent LO2 cell culture, certain cells were surrounded by their neighbors, suffered "collective attack", and were then made round in shape. Green fluorescent protein (GFP)-labeled cancer cells were also found to be squeezed by normal LO2 cells. Using the petri dish inversion model, we quantified the number of extrusion cells, and demonstrated that the ability of cancer cell extrusion was related to the metastatic potential of cancer cell lines. Our findings provide a novel model to detect crowdinginduced epithelial cell and cancer cell extrusion. This novel model provides a quantitative method for research into apoptotic and cancer cell extrusion, particularly in human hepatocellular carcinoma.展开更多
Mobile Crowd Sensing(MCS)is an emerging paradigm that leverages sensor-equipped smart devices to collect data.The introduction of MCS also poses some challenges such as providing highquality data for upper layer MCS a...Mobile Crowd Sensing(MCS)is an emerging paradigm that leverages sensor-equipped smart devices to collect data.The introduction of MCS also poses some challenges such as providing highquality data for upper layer MCS applications,which requires adequate participants.However,recruiting enough participants to provide the sensing data for free is hard for the MCS platform under a limited budget,which may lead to a low coverage ratio of sensing area.This paper proposes a novel method to choose participants uniformly distributed in a specific sensing area based on the mobility patterns of mobile users.The method consists of two steps:(1)A second-order Markov chain is used to predict the next positions of users,and select users whose next places are in the target sensing area to form a candidate pool.(2)The Average Entropy(DAE)is proposed to measure the distribution of participants.The participant maximizing the DAE value of a specific sensing area with different granular sub-areas is chosen to maximize the coverage ratio of the sensing area.Experimental results show that the proposed method can maximize the coverage ratio of a sensing area under different partition granularities.展开更多
文摘Despite growing research for residential crowding effects on housing market and public health perspectives, relatively little attention has been paid to explore and model spatial patterns of residential crowding over space. This paper focuses upon analyzing the spatial relationships between residential crowding and socio-demographic variables in Alexandria neighborhoods, Egypt. Global and local geo-statistical techniques were employed within GIS-based platform to identify spatial?variations of residential crowding determinates. The global ordinary least squares (OLS) model?assumes homogeneity of relationships between response variable and explanatory variables?across the study area. Consequently, it fails to account for heterogeneity of spatial relationships. Local model known as a geographically weighted regression (GWR) was also employed using the same?response variable and explanatory variables to capture spatial non-stationary of residential?crowding. A comparison of the outputs of both models indicated that OLS explained 74 percent of?residential crowding variations while GWR model explained 79 percent. The GWR improvedstrength of the model and provided a better goodness of fit than OLS. In addition, the findings of this analysis revealed that residential crowding was significantly associated with different structural measures particularly social characteristics of household such as higher education and illiteracy. Similarly, population size of neighborhood and number of dwelling rooms were found to have direct impacts on residential crowding rate. The spatial relationship of these measures distinctly varies over the study area.
基金the National Natural Science Foundation of China(Grant No.51108192 and 51208500).
文摘Overcrowding has become a non negligible issue for metros in China.This paper analyzes the impact of crowding in metro carriages on people’s travel behaviors based on the stated preference survey data from college students and full time workers in Guangzhou.The data were analyzed by using the constant value per trip model and the travel time multiplier model with the multinomial logit modeling technique.Results show that there is a significant impact of crowding in metro carriages on passengers’welfare.The relationship between the disutility of crowding and the standee density is not linear.Commuters do not care much about crowding in the metro,whereas non commuters and college students pay special attention to crowding in metro carriages,especially when the carriage is crowded.This paper presents new findings of the impact of demographic characteristics on the evaluation of crowding in metro carriages in developing countries.
基金supported by Drothermal project of The French National Research Agency(ANR-20-CE02-0011-01)supported by the Royal Society(RGS/R2/202220)a BBSRC grant(BB/V015249/1).
文摘Intraspecific competition at the larval stage is an important ecological factor affecting life-history,adaptation and evolutionary trajectory in holometabolous insects.However,the molecular pathways underpinning these ecological processes are poorly characterized.We reared Drosophila melanogaster at three egg densities(5,60,and 300 eggs/mL)and sequenced the transcriptomes of pooled third-instar larvae.We also examined emergence time,egg-to-adult viability,adult mass,and adult sex-ratio at each density.Medium crowding had minor detrimental effects on adult phenotypes compared to low density and yielded 24 differentially expressed genes(DEGs),including several chitinase enzymes.In contrast,high crowding had substantial detrimental effects on adult phenotypes and yielded 2107 DEGs.Among these,upregulated gene sets were enriched in sugar,steroid and amino acid metabolism as well as DNA replication pathways,whereas downregulated gene sets were enriched in ABC transporters,taurine,Toll/Imd signaling,and P450 xenobiotics metabolism pathways.Overall,our findings show that larval crowding has a large consistent effect on several molecular pathways(i.e.,core responses)with few pathways displaying density-specific regulation(i.e.,idiosyncratic responses).This provides important insights into how holometabolous insects respond to intraspecific competition during development.
基金supported by the Project entitled“Indo-Danish Collaboration for Data-driven Control and Optimization for a Highly Efficient Distribution Grid (ID-EDGe)”funded by Department of Science and Technology (DST),India (No.DST-1390-EED)。
文摘The dynamic pricing environment offers flexibility to the consumers to reschedule their switching appliances.Though the dynamic pricing environment results in several benefits to the utilities and consumers,it also poses some challenges.The crowding among residential customers is one of such challenges.The scheduling of loads at low-cost intervals causes crowding among residential customers,which leads to a fall in voltage of the distribution system below its prescribed limits.In order to prevent crowding phenomena,this paper proposes a priority-based demand response program for local energy communities.In the program,past contributions made by residential houses and demand are considered as essential parameters while calculating the priority factor.The non-linear programming(NLP)model proposed in this study seeks to reschedule loads at low-cost intervals to alleviate crowding phenomena.Since the NLP model does not guarantee global optima due to its non-convex nature,a second-order cone programming model is proposed,which captures power flow characteristics and guarantees global optimum.The proposed formulation is solved using General Algebraic Modeling System(GAMS)software and is tested on a 12.66 kV IEEE 33-bus distribution system,which demonstrates its applicability and efficacy.
基金Double First-Class Innovation Research Project for People’s Public Security University of China(2023SYL08).
文摘Crowd counting is a promising hotspot of computer vision involving crowd intelligence analysis,achieving tremendous success recently with the development of deep learning.However,there have been stillmany challenges including crowd multi-scale variations and high network complexity,etc.To tackle these issues,a lightweight Resconnection multi-branch network(LRMBNet)for highly accurate crowd counting and localization is proposed.Specifically,using improved ShuffleNet V2 as the backbone,a lightweight shallow extractor has been designed by employing the channel compression mechanism to reduce enormously the number of network parameters.A light multi-branch structure with different expansion rate convolutions is demonstrated to extract multi-scale features and enlarged receptive fields,where the information transmission and fusion of diverse scale features is enhanced via residual concatenation.In addition,a compound loss function is introduced for training themethod to improve global context information correlation.The proposed method is evaluated on the SHHA,SHHB,UCF-QNRF and UCF_CC_50 public datasets.The accuracy is better than those of many advanced approaches,while the number of parameters is smaller.The experimental results show that the proposed method achieves a good tradeoff between the complexity and accuracy of crowd counting,indicating a lightweight and high-precision method for crowd counting.
文摘Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, manyresearchers proposed game theoreticmodels to avoid and remove obstacles for crowd evacuation. Game theoreticalmodels aim to study and analyze the strategic behaviors of individuals within a crowd and their interactionsduring the evacuation. Game theoretical models have some limitations in the context of crowd evacuation. Thesemodels consider a group of individuals as homogeneous objects with the same goals, involve complex mathematicalformulation, and cannot model real-world scenarios such as panic, environmental information, crowds that movedynamically, etc. The proposed work presents a game theoretic model integrating an agent-based model to removethe obstacles from exits. The proposed model considered the parameters named: (1) obstacle size, length, andwidth, (2) removal time, (3) evacuation time, (4) crowd density, (5) obstacle identification, and (6) route selection.The proposed work conducts various experiments considering different conditions, such as obstacle types, obstacleremoval, and several obstacles. Evaluation results show the proposed model’s effectiveness compared with existingliterature in reducing the overall evacuation time, cell selection, and obstacle removal. The study is potentially usefulfor public safety situations such as emergency evacuations during disasters and calamities.
基金the Humanities and Social Science Fund of the Ministry of Education of China(21YJAZH077)。
文摘In a crowd density estimation dataset,the annotation of crowd locations is an extremely laborious task,and they are not taken into the evaluation metrics.In this paper,we aim to reduce the annotation cost of crowd datasets,and propose a crowd density estimation method based on weakly-supervised learning,in the absence of crowd position supervision information,which directly reduces the number of crowds by using the number of pedestrians in the image as the supervised information.For this purpose,we design a new training method,which exploits the correlation between global and local image features by incremental learning to train the network.Specifically,we design a parent-child network(PC-Net)focusing on the global and local image respectively,and propose a linear feature calibration structure to train the PC-Net simultaneously,and the child network learns feature transfer factors and feature bias weights,and uses the transfer factors and bias weights to linearly feature calibrate the features extracted from the Parent network,to improve the convergence of the network by using local features hidden in the crowd images.In addition,we use the pyramid vision transformer as the backbone of the PC-Net to extract crowd features at different levels,and design a global-local feature loss function(L2).We combine it with a crowd counting loss(LC)to enhance the sensitivity of the network to crowd features during the training process,which effectively improves the accuracy of crowd density estimation.The experimental results show that the PC-Net significantly reduces the gap between fullysupervised and weakly-supervised crowd density estimation,and outperforms the comparison methods on five datasets of Shanghai Tech Part A,ShanghaiTech Part B,UCF_CC_50,UCF_QNRF and JHU-CROWD++.
基金funded by Naif Arab University for Security Sciences under grant No.NAUSS-23-R10.
文摘Estimation of crowd count is becoming crucial nowadays,as it can help in security surveillance,crowd monitoring,and management for different events.It is challenging to determine the approximate crowd size from an image of the crowd’s density.Therefore in this research study,we proposed a multi-headed convolutional neural network architecture-based model for crowd counting,where we divided our proposed model into two main components:(i)the convolutional neural network,which extracts the feature across the whole image that is given to it as an input,and(ii)the multi-headed layers,which make it easier to evaluate density maps to estimate the number of people in the input image and determine their number in the crowd.We employed the available public benchmark crowd-counting datasets UCF CC 50 and ShanghaiTech parts A and B for model training and testing to validate the model’s performance.To analyze the results,we used two metrics Mean Absolute Error(MAE)and Mean Square Error(MSE),and compared the results of the proposed systems with the state-of-art models of crowd counting.The results show the superiority of the proposed system.
文摘AIM:To compare superficial and deep vascular properties of optic discs between crowded discs and controls using optical coherence tomography angiography(OCT-A).METHODS:Thirty patients with crowded discs,and 47 control subjects were enrolled in the study.One eye of each individual was included and OCT-A scans of optic discs were obtained in a 4.5×4.5 mm^(2) rectangular area.Radial peripapillary capillary(RPC)density,peripapillary retinal nerve fiber layer(pRNFL)thickness,cup volume,rim area,disc area,cup-to-disc(c/d)area ratio,and vertical c/d ratio were obtained automatically using device software.Automated parapapillary choroidal microvasculature(PPCMv)density was calculated using MATLAB software.When the vertical c/d ratio of the optic disc was absent or small cup,it was considered as a crowded disc.RESULTS:The mean signal strength index of OCT-A images was similar between the crowded discs and control eyes(P=0.740).There was no difference in pRNFL between the two groups(P=0.102).There were no differences in RPC density in whole image(P=0.826)and peripapillary region(P=0.923),but inside disc RPC density was higher in crowded optic discs(P=0.003).The PPCMv density in the inner-hemisuperior region was also lower in crowded discs(P=0.026).The pRNFL thickness was positively correlated with peripapillary RPC density(r=0.498,P<0.001).The inside disc RPC density was negatively correlated with c/d area ratio(r=-0.341,P=0.002).CONCLUSION:The higher inside disc RPC density and lower inner-hemisuperior PPCMv density are found in eyes with crowded optic discs.
文摘This paper introduces a novel variant of particle swarm optimization that leverages local displacements through attractors for addressing multiobjective optimization problems. The method incorporates a square root distance mechanism into the external archives to enhance the diversity. We evaluate the performance of the proposed approach on a set of constrained and unconstrained multiobjective test functions, establishing a benchmark for comparison. In order to gauge its effectiveness relative to established techniques, we conduct a comprehensive comparison with well-known approaches such as SMPSO, NSGA2 and SPEA2. The numerical results demonstrate that our method not only achieves efficiency but also exhibits competitiveness when compared to evolutionary algorithms. Particularly noteworthy is its superior performance in terms of convergence and diversification, surpassing the capabilities of its predecessors.
文摘GaN-based vertical P-i-N diode with mesa edge terminal structure due to electric field crowding effect, the breakdown voltage of the device is significantly reduced. This work investigates three terminal structures, including deeply etched, bevel, and stepped-mesas terminal structures, to suppress electric field crowding effects at the device and junction edges. Deeply-etched mesa terminal yields a breakdown voltage of 1205 V, i.e., 89% of the ideal voltage. The bevel-mesa terminal achieves about 89% of the ideal breakdown voltage, while the step-mesa terminal is less effective in mitigating electric field crowding, at about 32% of the ideal voltage. This work can provide an important reference for the design of high-power, high-voltage GaN-based P-i-N power devices, finding a terminal protection structure suitable for GaNPiN diodes to further enhance the breakdown performance of the device and to unleash the full potential of GaN semiconductor materials.
基金This project is supported by Provincial Science Foundation of Hebei (No.01213553).
文摘An extended crowding genetic algorithm (ECGA) is introduced for solvingoptimal pump configuration problem, which was presented by T. Westerlund in 1994. This problem hasbeen found to be non-convex, and the objective function contained several local optima and globaloptimality could not be ensured by all the traditional MINLP optimization method. The concepts ofspecies conserving and composite encoding are introduced to crowding genetic algorithm (CGA) formaintain the diversity of population more effectively and coping with the continuous and/or discretevariables in MINLP problem. The solution of three-levels pump configuration got from DICOPT++software (OA algorithm) is also given. By comparing with the solutions obtained from DICOPT++, ECPmethod, and MIN-MIN method, the ECGA algorithm proved to be very effective in finding the globaloptimal solution of multi-levels pump configuration via using the problem-specific information.
基金supported by the National Natural Science Foundation of China(11271120,11426099)the Project of Hunan Natural Science Foundation of China(13JJ3085)
文摘This paper deals with the global dynamical behaviors of the positive solutions for a parabolic type ratio-dependent predator-prey system with a crowding term in the prey equation, where it is assumed that the coefficient of the functional response is less than the coefficient of the intrinsic growth rates of the prey species. We demonstrated some special dynamical behaviors of the positive solutions of this system which the persistence of the coexistence of two species can be obtained when the crowding region in the prey equation only is designed suitably. Furthermore, we can obtain that under some conditions, the unique positive steady state solution of the system is globally asymptotically stable.
基金the National Key R&D Program of China(No.2017YFB0404001)the Central Public-Interest Scientific Institution Basal Research Fund,CAFS(No.2017HYZD04)+1 种基金the Qingdao Shinan District Science and Technology Bureau(No.2016-3-006)the Modern Agriculture Industry System Construction Special Funds(No.CARS-47-G24).
文摘In this study,juvenile turbot Scophthalmus maximus were vaccinated with attenuated Edwardsiella tarda(EIBAV1)and reared at two different densities,low density(LD),(5.25±0.02)kg m−2,as control group and high density(HD),(20.53±0.05)kg m−2,as experimental group.Only density was considered as the variable.Five weeks after vaccination,the transcriptomes of spleen and head kidney from the turbot in two groups were analyzed with RNA-Seq technology.A total of 447 million reads were assembled into 41136 genes with an average length of 1274 bp and a N50 size of 2295 bp.A comparison of gene expression between HD and LD groups revealed 1155 differentially expressed genes(DEGs).Enrichment and pathway analysis of the 10 immune-related DEGs showed the centrality of toll-like receptor signaling pathway,cytosolic DNA-sensing pathway and platelet activation in the host immune responses.The 5 overexpressed inflammatory cytokines and 5 downregulated signal-regulated cytokines genes are covered by these immune-related DEGs.It was inferred that cells suffer damage and the immune response is restrained in turbot under crowding stress.
基金the Hunan Provincial Natural Science Foundation of China(2019JJ40079,2019JJ50160)the Scientific Research Fund of Hunan Provincial Education Department(16A071,19A179)the National Natural Science Foundation of China(11701169)。
文摘This paper deals with a Lotka-Volterra predator-prey model with a crowding term in the predator equation.We obtain a critical value λ1^D(Ω0),and demonstrate that the existence of the predator inΩ0 only depends on the relationship of the growth rateμof the predator and λ1^D(Ω0),not on the prey.Furthermore,whenμ<λ1^D(Ω0),we obtain the existence and uniqueness of its positive steady state solution,while whenμ≥λ1^D(Ω0),the predator and the prey cannot coexist inΩ0.Our results show that the coexistence of the prey and the predator is sensitive to the size of the crowding regionΩ0,which is different from that of the classical Lotka-Volterra predator-prey model.
文摘This study analyzes drift phenomena of deterministic crowding and probabilistic crowding by using equivalence class model and expectation proportion equations. It is proved that the replacement errors of deterministic crowding cause the population converging to a single individual, thus resulting in premature stagnation or losing optional optima. And probabilistic crowding can maintain equilibrium multiple subpopulations as the population size is adequate large. An improved niching method using clustering crowding is proposed. By analyzing topology of fitness landscape using hill valley function and extending the search space for similarity analysis, clustering crowding determines the locality of search space more accurately, thus greatly decreasing replacement errors of crowding. The integration of deterministic and probabilistic replacement increases the capacity of both parallel local hill climbing and maintaining multiple subpopulations. The experimental results optimizing various multimodal functions show that,the performances of clustering crowding, such as the number of effective peaks maintained, average peak ratio and global optimum ratio are uniformly superior to those of the evolutionary algorithms using fitness sharing, simple deterministic crowding and probabilistic crowding.
文摘This study was undertaken to examine which factors contributed to the correction of crowding in two patients who underwent nonextraction orthodontic treatment. A study model analysis was conducted to determine the effects of the orthodontic treatment for crowding with high canines on crown angulation and dental arch width in two patients. The results showed that the crown angulation was significantly increased, indicating distal tipping in the maxillary dental arch. This tendency was most commonly observed in the premolars among the lateral teeth. With respect to the dental arch width, the largest change was evident in the first molar and first premolar regions in cases 1 and 2, respectively. On the basis of these results, up-righting of mesially tipped lateral teeth and expansion of narrow dental arches could prove to be the keys to the success of space regaining or correction of high canines and mild crowding.
文摘BACKGROUND:In patients with chest pain who arrive at the emergency department(ED)by ambulance,venous access is frequently established prehospital,and could be utilized to sample blood.Prehospital blood sampling may save time in the diagnostic process.In this study,the association of prehospital blood draw with blood sample arrival times,troponin turnaround times,and ED length of stay(LOS),number of blood sample mix-ups and blood sample quality were assessed.METHODS:The study was conducted from October 1,2019 to February 29,2020.In patients who were transported to the ED with acute chest pain with low suspicion for acute coronary syndrome(ACS),outcomes were compared between cases,in whom prehospital blood draw was performed,and controls,in whom blood was drawn at the ED.Regression analyses were used to assess the association of prehospital blood draw with the time intervals.RESULTS:Prehospital blood draw was performed in 100 patients.In 406 patients,blood draw was performed at the ED.Prehospital blood draw was independently associated with shorter blood sample arrival times,shorter troponin turnaround times and decreased LOS(P<0.001).No differences in the number of blood sample mix-ups and quality were observed(P>0.05).CONCLUSION:For patients with acute chest pain with low suspicion for ACS,prehospital blood sampling is associated with shorter time intervals,while there were no significant differences between the two groups in the validity of the blood samples.
基金This study was supported by the National Natural Science Foundation of China (No.81472311,No.81572419 and No.81702396).
文摘Overcrowding and cell deformation lead to the shedding of apoptotic and live cells to maintain homeostasis in the epithelium. Recent studies have attempted to explain the effect of extrusion on epithelial homeostasis and tumor metastasis, but lack the requisite quantitative models for testing extrusion. Here, we designed a petri dish inversion model to detect the extrusion ability of both normal epithelial cells and epithelial cancer cells. Firstly, we found cell extrusion was observed in both normal epithelial cells (LO2 cells) and cancer cells;in confluent LO2 cell culture, certain cells were surrounded by their neighbors, suffered "collective attack", and were then made round in shape. Green fluorescent protein (GFP)-labeled cancer cells were also found to be squeezed by normal LO2 cells. Using the petri dish inversion model, we quantified the number of extrusion cells, and demonstrated that the ability of cancer cell extrusion was related to the metastatic potential of cancer cell lines. Our findings provide a novel model to detect crowdinginduced epithelial cell and cancer cell extrusion. This novel model provides a quantitative method for research into apoptotic and cancer cell extrusion, particularly in human hepatocellular carcinoma.
基金supported by the Open Foundation of State key Laboratory of Networking and Switching Technology(Beijing University of Posts and Telecommunications)(SKLNST-2021-1-18)the General Program of Natural Science Foundation of Chongqing(cstc2020jcyj-msxmX1021)+1 种基金the Science and Technology Research Program of Chongqing Municipal Education Commission(KJZD-K202000602)Chongqing graduate research and innovation project(CYS22478).
文摘Mobile Crowd Sensing(MCS)is an emerging paradigm that leverages sensor-equipped smart devices to collect data.The introduction of MCS also poses some challenges such as providing highquality data for upper layer MCS applications,which requires adequate participants.However,recruiting enough participants to provide the sensing data for free is hard for the MCS platform under a limited budget,which may lead to a low coverage ratio of sensing area.This paper proposes a novel method to choose participants uniformly distributed in a specific sensing area based on the mobility patterns of mobile users.The method consists of two steps:(1)A second-order Markov chain is used to predict the next positions of users,and select users whose next places are in the target sensing area to form a candidate pool.(2)The Average Entropy(DAE)is proposed to measure the distribution of participants.The participant maximizing the DAE value of a specific sensing area with different granular sub-areas is chosen to maximize the coverage ratio of the sensing area.Experimental results show that the proposed method can maximize the coverage ratio of a sensing area under different partition granularities.