A novel {[bis（pyridine-κN）bis（3,5-dinitrosalicylato κ-O,O＇）Zn（Ⅱ）][bis（pyridine-κN）Zn（Ⅱ）]}（C_（34）H_（24）N_8O_（14）Zn_2） was synthesized by a self-assemble method at room temperature. The molecular...A novel {[bis（pyridine-κN）bis（3,5-dinitrosalicylato κ-O,O＇）Zn（Ⅱ）][bis（pyridine-κN）Zn（Ⅱ）]}（C_（34）H_（24）N_8O_（14）Zn_2） was synthesized by a self-assemble method at room temperature. The molecular structure was determined by single-crystal X-ray analysis. The compound crystallizes in the monoclinic system, space group P2_1/n with a = 12.2156, b = 13.5696, c = 22.5602 A, β = 90.061o, Z = 4 and V = 3739.6（3）A^3. The new 1D binuclear coordination polymer {[bis（py-κN）bis（3,5-dinitrosal κ-O,O′） Zn（Ⅱ）][bis（py-κN）Zn（Ⅱ）]} resulted from two different types of moieties. The polymer [bis（py-κN）bis（3,5-dinitrosal κ-O,O′）Zn（Ⅱ）] unit is connected with [bis（py-κN） Zn（Ⅱ）] by zigzag topology. One zinc（Ⅱ） cation has a six-fold coordination environment, in which the metal atom is connected with four oxygen atoms of two 3,5-dinitrosalicylic acids to form equatorial bonds and two nitrogen atoms of pyridine to generate the axial bonds. Other four-fold nucleus contain two Zn-O bonds from different 3,5-dinitrosalicylic acids and two bonds with the Natom of pyridine. Antimicrobial assay results indicated that the compound showed moderate activities against different bacterial and fungal strains.展开更多
The title compound 1-（3-（（benzo[d][1,3]dioxol-5-yloxy）methyl）phenethyl）-4- phenylpiperidin-4-ol （4, C27H29NO4, Mr = 431.51） was synthesized by a four-step reaction and characterized by 1H NMR, 13C NMR, element...The title compound 1-（3-（（benzo[d][1,3]dioxol-5-yloxy）methyl）phenethyl）-4- phenylpiperidin-4-ol （4, C27H29NO4, Mr = 431.51） was synthesized by a four-step reaction and characterized by 1H NMR, 13C NMR, elemental analysis and single-crystal X-ray diffraction. The crystal is of triclinic, space group P1 with a = 5.8033（12）, b = 10.705（2）, c = 18.393（4）A, a = 83A4（3）, β = 82.71（3）, γ = 88.88 （3）°, V= 1126.0（4） A3, Z= 1, Dc= 1.273 g/cm3, S = 1.070, p = 0.681 mm^-1, F（000） = 460, R = 0.0618 and wR = 0.1619 for 6452 observed reflections with I 〉 2σ（I） Geometry conformations revealed that the dihedral angle between benzodioxole and aromatic planes contributed to the formation of C-H…π interactions. Hydrogen bonds and van der waals interactions were observed to stabilize the three-dimensional packing structure. The compound showed a moderate inhibitory activity against the prostate cancer cells.展开更多
The compound 3,3＇-（anthracene-9,10-diyl）bis（1-phenylpropan-1-one）（C32H26O2,Mr=442.55） has been synthesized by the reaction of 2,2＇-（anthracene-9,10-diylbis（methy-lene））bis（1,3-diphenylpropane-1,3-dione） ...The compound 3,3＇-（anthracene-9,10-diyl）bis（1-phenylpropan-1-one）（C32H26O2,Mr=442.55） has been synthesized by the reaction of 2,2＇-（anthracene-9,10-diylbis（methy-lene））bis（1,3-diphenylpropane-1,3-dione） with CsCO3,and its structure was characterized by 1H NMR and single-crystal X-ray diffraction.The crystal of the title compound belongs to monoclinic,space group P21/c with a=9.154（3）,b=5.2777（16）,c=24.897（7） nm,β=107.337（10）°,Z=2 and V=1.1482 nm3.X-ray analysis indicates that an intermolecular hydrogen bond C（8）-H（8A）…O（1）,weak C-H···π between H（9A） and the centre of anthracene rings and weak π-π interactions between two anthracene ring planes are observed.展开更多
The title compound S,S?bis(8-quinolyl)-1,8-dithiaoctane crystallizes in the monoclinic system, space group P21/n with a = 7.537(1), b = 20.434(3), c = 13.857(2) , = 97.102(3)? V = 2117.8(5) 3, Dc = 1.269 g/cm3, Z = ...The title compound S,S?bis(8-quinolyl)-1,8-dithiaoctane crystallizes in the monoclinic system, space group P21/n with a = 7.537(1), b = 20.434(3), c = 13.857(2) , = 97.102(3)? V = 2117.8(5) 3, Dc = 1.269 g/cm3, Z = 4, C24H24N2S2, Mr = 404.57, (MoK? = 0.263 mm-1 and F(000) = 856, and its structure was refined to R = 0.0417 and wR = 0.1077 for 2814 observed reflections (I > 2(I)). The compound crystallizes in conformations A and B with equal occupation ratio. A acts as both a donor and acceptor in the CH… interactions, but B only acts as a donor. Edge-to-face CH…?interactions between AA along the a axis and BABA along the c axis result in an infinite layered-structure in the ac plane.展开更多
文摘A novel {[bis（pyridine-κN）bis（3,5-dinitrosalicylato κ-O,O＇）Zn（Ⅱ）][bis（pyridine-κN）Zn（Ⅱ）]}（C_（34）H_（24）N_8O_（14）Zn_2） was synthesized by a self-assemble method at room temperature. The molecular structure was determined by single-crystal X-ray analysis. The compound crystallizes in the monoclinic system, space group P2_1/n with a = 12.2156, b = 13.5696, c = 22.5602 A, β = 90.061o, Z = 4 and V = 3739.6（3）A^3. The new 1D binuclear coordination polymer {[bis（py-κN）bis（3,5-dinitrosal κ-O,O′） Zn（Ⅱ）][bis（py-κN）Zn（Ⅱ）]} resulted from two different types of moieties. The polymer [bis（py-κN）bis（3,5-dinitrosal κ-O,O′）Zn（Ⅱ）] unit is connected with [bis（py-κN） Zn（Ⅱ）] by zigzag topology. One zinc（Ⅱ） cation has a six-fold coordination environment, in which the metal atom is connected with four oxygen atoms of two 3,5-dinitrosalicylic acids to form equatorial bonds and two nitrogen atoms of pyridine to generate the axial bonds. Other four-fold nucleus contain two Zn-O bonds from different 3,5-dinitrosalicylic acids and two bonds with the Natom of pyridine. Antimicrobial assay results indicated that the compound showed moderate activities against different bacterial and fungal strains.
基金supported by the Natural Science Foundation of Guangdong Province(No.S2013040014088)the Postdoctoral Science Foundation of Guangzhou City(Q188)
文摘The title compound 1-（3-（（benzo[d][1,3]dioxol-5-yloxy）methyl）phenethyl）-4- phenylpiperidin-4-ol （4, C27H29NO4, Mr = 431.51） was synthesized by a four-step reaction and characterized by 1H NMR, 13C NMR, elemental analysis and single-crystal X-ray diffraction. The crystal is of triclinic, space group P1 with a = 5.8033（12）, b = 10.705（2）, c = 18.393（4）A, a = 83A4（3）, β = 82.71（3）, γ = 88.88 （3）°, V= 1126.0（4） A3, Z= 1, Dc= 1.273 g/cm3, S = 1.070, p = 0.681 mm^-1, F（000） = 460, R = 0.0618 and wR = 0.1619 for 6452 observed reflections with I 〉 2σ（I） Geometry conformations revealed that the dihedral angle between benzodioxole and aromatic planes contributed to the formation of C-H…π interactions. Hydrogen bonds and van der waals interactions were observed to stabilize the three-dimensional packing structure. The compound showed a moderate inhibitory activity against the prostate cancer cells.
基金Supported by the National Natural Science Foundation of China (No. 20772152) and the State Key Laboratory of Structural Chemistry
文摘The compound 3,3＇-（anthracene-9,10-diyl）bis（1-phenylpropan-1-one）（C32H26O2,Mr=442.55） has been synthesized by the reaction of 2,2＇-（anthracene-9,10-diylbis（methy-lene））bis（1,3-diphenylpropane-1,3-dione） with CsCO3,and its structure was characterized by 1H NMR and single-crystal X-ray diffraction.The crystal of the title compound belongs to monoclinic,space group P21/c with a=9.154（3）,b=5.2777（16）,c=24.897（7） nm,β=107.337（10）°,Z=2 and V=1.1482 nm3.X-ray analysis indicates that an intermolecular hydrogen bond C（8）-H（8A）…O（1）,weak C-H···π between H（9A） and the centre of anthracene rings and weak π-π interactions between two anthracene ring planes are observed.
基金the National Natural Science Foundation of China and Natural Science Foundation of Guangdong province
文摘The title compound S,S?bis(8-quinolyl)-1,8-dithiaoctane crystallizes in the monoclinic system, space group P21/n with a = 7.537(1), b = 20.434(3), c = 13.857(2) , = 97.102(3)? V = 2117.8(5) 3, Dc = 1.269 g/cm3, Z = 4, C24H24N2S2, Mr = 404.57, (MoK? = 0.263 mm-1 and F(000) = 856, and its structure was refined to R = 0.0417 and wR = 0.1077 for 2814 observed reflections (I > 2(I)). The compound crystallizes in conformations A and B with equal occupation ratio. A acts as both a donor and acceptor in the CH… interactions, but B only acts as a donor. Edge-to-face CH…?interactions between AA along the a axis and BABA along the c axis result in an infinite layered-structure in the ac plane.
