There is substantial individual variation in the growth rates of sea cucumber Apostichopus japonicus individuals. This necessitates additional work to grade the seed stock and lengthens the production period. We evalu...There is substantial individual variation in the growth rates of sea cucumber Apostichopus japonicus individuals. This necessitates additional work to grade the seed stock and lengthens the production period. We evaluated the infl uence of three culture methods(free-mixed, isolated-mixed, isolated-alone) on individual variation in growth and assessed the relationship between feeding, energy conversion efficiency, and individual growth variation in individually cultured sea cucumbers. Of the different culture methods, animals grew best when reared in the isolated-mixed treatment(i.e., size classes were held separately), though there was no difference in individual variation in growth between rearing treatment groups. The individual variation in growth was primarily attributed to genetic factors. The difference in food conversion efficiency caused by genetic differences among individuals was thought to be the origin of the variance. The level of individual growth variation may be altered by interactions among individuals and environmental heterogeneity. Our results suggest that, in addition to traditional seed grading, design of a new kind of substrate that changes the spatial distribution of sea cucumbers would effectively enhance growth and reduce individual variation in growth of sea cucumbers in culture.展开更多
The thesis analysis Chinese collectivism and American individualism mainly from food culture.The thesis has four parts.The first part expounds the two different values' concept.The second part analysis the two dif...The thesis analysis Chinese collectivism and American individualism mainly from food culture.The thesis has four parts.The first part expounds the two different values' concept.The second part analysis the two different values in detail from the way of cooking,diet style,dietary ideas and different types of payment through comparison.Chinese pay attention to seasoning,while America natural taste in the way of preparing;Chinese diet style is group dining system,while American diet style is individual dining system;Chinese dietary idea is emotional,while American dietary idea is rational;Chinese like my treat,American like go Dutch.The third part expounds the reasons of different values reflected in the two food culture.And it analysis the main reason from four part above mentioned in detail.The fourth part expounds that the paper aims at letting us learn about two countries' deep-structure culture hidden in food culture.And then we can keep the communication open.展开更多
Background:Patients with pancreatic ductal adenocarcinoma(PDAC)who undergo surgical resection and receive effective chemotherapy have the best chance for longterm survival.Unfortunately,because of the heterogeneity of...Background:Patients with pancreatic ductal adenocarcinoma(PDAC)who undergo surgical resection and receive effective chemotherapy have the best chance for longterm survival.Unfortunately,because of the heterogeneity of pancreatic cancer,it is difficult to find a personalized treatment strategy for patients.Organoids are ideal preclinical models for personalized medicine.Therefore,we explore the cultivation conditions and construction methods of PDAC organoid models to screen the individualized therapy strategy.Methods:Fresh PDAC tissues from surgical resection were collected and digested with digestive enzymes;then the tumor cells were embedded in Matrigel with a suitable medium to establish the PDAC organoid models.The genetic stability of the organoids was analyzed using whole exon sequencing;hematoxylin and eosin staining and immunohistochemistry of organoids were performed to analyze their consistency with the pathological morphology of the patient's tumor tissue;After 2 days of organoid culture,we selected four commonly used clinical chemotherapy drugs for single or combined treatment to analyze drug sensitivity.Results:Two cases of PDAC organoid models were successfully established,and the results of their pathological characteristics and exome sequencing were consistent with those of the patient's tumor tissue.Both PDAC organoids showed more sensitivity to gemcitabine and cisplatin,and the combined treatment was more effective than monotherapy.Conclusion:Both organoids better retained the pathological characteristics,genomic stability,and heterogeneity with the original tumor.Individual PDAC organoids exhibited different sensitivities to the same drugs.Thus,this study provided ideal experimental models for screening individualized therapy strategy for patients with PDAC.展开更多
Western culture emphasizes on individualism,individual freedom and personal choice,while Chinese people put more emphasis on collectivism.Collectivism-Individualism value differences can also be reflected in Chinese a...Western culture emphasizes on individualism,individual freedom and personal choice,while Chinese people put more emphasis on collectivism.Collectivism-Individualism value differences can also be reflected in Chinese and Western Family Relationships,which may sometimes lead to conflicts between the couples in the cross-cultural marriage and their families.展开更多
Objective Independent from noise exposure, noise sensitivity plays a pivotal role in people's noise annoyance perception and concomitant health deteriorations. The present study empirically investigated the psychomet...Objective Independent from noise exposure, noise sensitivity plays a pivotal role in people's noise annoyance perception and concomitant health deteriorations. The present study empirically investigated the psychometric properties of the Chinese version of the Weinstein Noise Sensitivity Scale-Short Form (CNSS-SF), the widely used inventory measuring individual differences in noise perception.Methods In total, 373 Chinese participants (age = 21.41 ± 3.36) completed the online, anonymous questionnaire package. Examination of the CNSS-SF's reliability (internal consistency), factorial validity through validation and cross-validation, nomological validity and measurement invariance across gender groups were undertaken.Results The Cronbach alpha coefficients and composite reliabilities indicated sufficient reliability of the CNSS-SF. Two confirmatory factor analyses (CFA), in two randomly partitioned groups of participants, substantiated the factorial validity of the scale. The nomological validity of the scale was also corroborated by the significant positive association of its score with the trait anxiety score. Measurement invariance of the CNSS-SF was also found across genders via multi-group CFA.Conclusion Though not without limitations, findings from the present research provide promising evidence for the utility of the scale in measuring noise sensitivity among the Chinese population. The availability of the CNSS-SF can promote research related to environmental noise and health in China, as well as facilitate cross-cultural comparisons.展开更多
The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding sign...The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding significance to translation practice.展开更多
In recent years,the Chinese beverage market has become more mature and customers have changed their priorities when buying drinks.Furthermore,Chinese people who are more likely to focus on group interests tend to have...In recent years,the Chinese beverage market has become more mature and customers have changed their priorities when buying drinks.Furthermore,Chinese people who are more likely to focus on group interests tend to have more collectivism.The purpose of this article is to analyze the reasons why the investments of American beverage corporates and the American individualism should be welcomed.The findings are(1)Coca-Cola Company have more strengths and opportunities than weaknesses when they advertise in China;(2)the carbonated industry is predicted to have a not very bright future;(3)the methods that American beverage industry advertise make Chinese people’s lives colorful owing to their advocacies and CSR awareness;(4)American individualism can push Chinese employees to be more competent.展开更多
In China,individualism is translated into "个人主义",whereas in western culture,the connotation of individualism doesn't equal to "个人主义" in China.Individualism is the soul of western cultur...In China,individualism is translated into "个人主义",whereas in western culture,the connotation of individualism doesn't equal to "个人主义" in China.Individualism is the soul of western culture which consists of the core part of western civilization,however,when interpreted into Chinese,individualism represents selfish.It is obvious that individualism is turned from positive into negative.The paper attempts at the proper translation and proves into the equivalence theory to find the reason.展开更多
The world could be analyzed in many dimensions,like rich and poor,peace and warfare,equal and oppressive,but one of the most important dimensions may be the difference between different societies of individualist and ...The world could be analyzed in many dimensions,like rich and poor,peace and warfare,equal and oppressive,but one of the most important dimensions may be the difference between different societies of individualist and collectivist.This article is trying to discuss is the difference between individualism and collectivism in the western and eastern cultures,and also will explain and discuss it in some aspects,such as their viewpoint,their attitude on self-enhancement and self-criticism,and the goal setting and motivation,and take some cases which some researches and psychologists did and some cases found for example to describe it.Also it presents that social orientation and environment,and culture background will take important role to impact people’s mind and choice on individualism and collectivism.No matter individual or collective,it all have advantage and disadvantage for each,it needs comprehensive evaluation for differential environment which can obtain relative reasonable conclusion.展开更多
基金Supported by the National Natural Science Foundation of China(No.41106134)the National Marine Public Welfare Research Project of China(No.201305043)+1 种基金the National High Technology Research and Development Program of China(863 Program)(No.2012AA10A412)the Agriculture Science Technology Achievement Transformation Fund(No.2012GB24910656)
文摘There is substantial individual variation in the growth rates of sea cucumber Apostichopus japonicus individuals. This necessitates additional work to grade the seed stock and lengthens the production period. We evaluated the infl uence of three culture methods(free-mixed, isolated-mixed, isolated-alone) on individual variation in growth and assessed the relationship between feeding, energy conversion efficiency, and individual growth variation in individually cultured sea cucumbers. Of the different culture methods, animals grew best when reared in the isolated-mixed treatment(i.e., size classes were held separately), though there was no difference in individual variation in growth between rearing treatment groups. The individual variation in growth was primarily attributed to genetic factors. The difference in food conversion efficiency caused by genetic differences among individuals was thought to be the origin of the variance. The level of individual growth variation may be altered by interactions among individuals and environmental heterogeneity. Our results suggest that, in addition to traditional seed grading, design of a new kind of substrate that changes the spatial distribution of sea cucumbers would effectively enhance growth and reduce individual variation in growth of sea cucumbers in culture.
文摘The thesis analysis Chinese collectivism and American individualism mainly from food culture.The thesis has four parts.The first part expounds the two different values' concept.The second part analysis the two different values in detail from the way of cooking,diet style,dietary ideas and different types of payment through comparison.Chinese pay attention to seasoning,while America natural taste in the way of preparing;Chinese diet style is group dining system,while American diet style is individual dining system;Chinese dietary idea is emotional,while American dietary idea is rational;Chinese like my treat,American like go Dutch.The third part expounds the reasons of different values reflected in the two food culture.And it analysis the main reason from four part above mentioned in detail.The fourth part expounds that the paper aims at letting us learn about two countries' deep-structure culture hidden in food culture.And then we can keep the communication open.
基金Laboratory Animal Foundation Program,Grant/Award Number:SYDW_KY 2021-14National Natural Science Foundation of China,Grant/Award Number:32070532 and 32270566+1 种基金Promotion Plan of the Air Force Medical University,Grant/Award Number:2020SWAQ11the Ethics Committee of Xijing Hospital of FMMU(ethics approval number:KY20203128-1).
文摘Background:Patients with pancreatic ductal adenocarcinoma(PDAC)who undergo surgical resection and receive effective chemotherapy have the best chance for longterm survival.Unfortunately,because of the heterogeneity of pancreatic cancer,it is difficult to find a personalized treatment strategy for patients.Organoids are ideal preclinical models for personalized medicine.Therefore,we explore the cultivation conditions and construction methods of PDAC organoid models to screen the individualized therapy strategy.Methods:Fresh PDAC tissues from surgical resection were collected and digested with digestive enzymes;then the tumor cells were embedded in Matrigel with a suitable medium to establish the PDAC organoid models.The genetic stability of the organoids was analyzed using whole exon sequencing;hematoxylin and eosin staining and immunohistochemistry of organoids were performed to analyze their consistency with the pathological morphology of the patient's tumor tissue;After 2 days of organoid culture,we selected four commonly used clinical chemotherapy drugs for single or combined treatment to analyze drug sensitivity.Results:Two cases of PDAC organoid models were successfully established,and the results of their pathological characteristics and exome sequencing were consistent with those of the patient's tumor tissue.Both PDAC organoids showed more sensitivity to gemcitabine and cisplatin,and the combined treatment was more effective than monotherapy.Conclusion:Both organoids better retained the pathological characteristics,genomic stability,and heterogeneity with the original tumor.Individual PDAC organoids exhibited different sensitivities to the same drugs.Thus,this study provided ideal experimental models for screening individualized therapy strategy for patients with PDAC.
文摘Western culture emphasizes on individualism,individual freedom and personal choice,while Chinese people put more emphasis on collectivism.Collectivism-Individualism value differences can also be reflected in Chinese and Western Family Relationships,which may sometimes lead to conflicts between the couples in the cross-cultural marriage and their families.
文摘Objective Independent from noise exposure, noise sensitivity plays a pivotal role in people's noise annoyance perception and concomitant health deteriorations. The present study empirically investigated the psychometric properties of the Chinese version of the Weinstein Noise Sensitivity Scale-Short Form (CNSS-SF), the widely used inventory measuring individual differences in noise perception.Methods In total, 373 Chinese participants (age = 21.41 ± 3.36) completed the online, anonymous questionnaire package. Examination of the CNSS-SF's reliability (internal consistency), factorial validity through validation and cross-validation, nomological validity and measurement invariance across gender groups were undertaken.Results The Cronbach alpha coefficients and composite reliabilities indicated sufficient reliability of the CNSS-SF. Two confirmatory factor analyses (CFA), in two randomly partitioned groups of participants, substantiated the factorial validity of the scale. The nomological validity of the scale was also corroborated by the significant positive association of its score with the trait anxiety score. Measurement invariance of the CNSS-SF was also found across genders via multi-group CFA.Conclusion Though not without limitations, findings from the present research provide promising evidence for the utility of the scale in measuring noise sensitivity among the Chinese population. The availability of the CNSS-SF can promote research related to environmental noise and health in China, as well as facilitate cross-cultural comparisons.
文摘The theory of linguistic individuality and second language individuality,especially the three-level structure of Y.N.Karaulov,reveals the two most important factors influencing translation,which has great guiding significance to translation practice.
文摘In recent years,the Chinese beverage market has become more mature and customers have changed their priorities when buying drinks.Furthermore,Chinese people who are more likely to focus on group interests tend to have more collectivism.The purpose of this article is to analyze the reasons why the investments of American beverage corporates and the American individualism should be welcomed.The findings are(1)Coca-Cola Company have more strengths and opportunities than weaknesses when they advertise in China;(2)the carbonated industry is predicted to have a not very bright future;(3)the methods that American beverage industry advertise make Chinese people’s lives colorful owing to their advocacies and CSR awareness;(4)American individualism can push Chinese employees to be more competent.
文摘In China,individualism is translated into "个人主义",whereas in western culture,the connotation of individualism doesn't equal to "个人主义" in China.Individualism is the soul of western culture which consists of the core part of western civilization,however,when interpreted into Chinese,individualism represents selfish.It is obvious that individualism is turned from positive into negative.The paper attempts at the proper translation and proves into the equivalence theory to find the reason.
文摘The world could be analyzed in many dimensions,like rich and poor,peace and warfare,equal and oppressive,but one of the most important dimensions may be the difference between different societies of individualist and collectivist.This article is trying to discuss is the difference between individualism and collectivism in the western and eastern cultures,and also will explain and discuss it in some aspects,such as their viewpoint,their attitude on self-enhancement and self-criticism,and the goal setting and motivation,and take some cases which some researches and psychologists did and some cases found for example to describe it.Also it presents that social orientation and environment,and culture background will take important role to impact people’s mind and choice on individualism and collectivism.No matter individual or collective,it all have advantage and disadvantage for each,it needs comprehensive evaluation for differential environment which can obtain relative reasonable conclusion.