目的比较CURB一65评分和强化CURB评分对老年重症社区获得性肺炎（severe community acquired pneumonia，SCAP）预后的临床预测价值。方法回顾性分析2009—12—2015-07入住我院急诊科、呼吸内科以及老年呼吸内科的87例老年SCAP相关临床...目的比较CURB一65评分和强化CURB评分对老年重症社区获得性肺炎（severe community acquired pneumonia，SCAP）预后的临床预测价值。方法回顾性分析2009—12—2015-07入住我院急诊科、呼吸内科以及老年呼吸内科的87例老年SCAP相关临床资料，分别统计每例患者的CURB-65评分、强化CURB评分，以患者28d预后为临床观察终点，绘制受试者工作特征（receiver operator characteristic，ROC）曲线，通过比较曲线下面积（area under the curve，AUC）分析两种评分工具对老年SCAP预后的预测价值。结果87例患者CURB一65评分为3（2—3）分，强化CURB评分为11（10～12）分。死亡组中CURB-65评分和强化CURB评分均明显高于存活组，差异有统计学意义（P〈0．05）。强化CURB评分AUC为0．722，最佳截断值为12，敏感度为58．82％，特异度为69．81％，P=0．0001；CURB-65评分AUC为0．660，最佳截断值为3，敏感度为73．53％，特异度为49．06％，P=0．0091。强化CURB评分AUC大于CURB-65评分，差异有统计学意义（0．722vs．0．660，Z=2．176，P=0．029）。结论CURB-65评分和强化CURB评分均可预测老年SCAP预后，强化CURB评分预测价值高于CURB-65评分，且其特异度高于CURB-65评分。展开更多
Background: Despiteits recommendation in management guide lines for community acquired pneumonia (CAP), the CURB65 score is frequently not followed for disposition decisions in clinical routine. We therefore proposed ...Background: Despiteits recommendation in management guide lines for community acquired pneumonia (CAP), the CURB65 score is frequently not followed for disposition decisions in clinical routine. We therefore proposed an improved CURB65 A score, supplemented by proadre nome dull in (ProADM) levels for patients with CAP and other lower respiratory tract infections (LRTIs). In this study, we vali dated this risk based biomarker enhanced disposition in patients with LRTIs presenting to the emergency department of the University Hospital of Basel. Methods: In this prospective observational cohort study of 85 patients presenting with LRTIs, site of care was decided by the physicians in charge according to their judgement. Retro spectively the CURB65 A score was calculated and a virtual disposition assigned. This was compared with the existing disposition in order to identify efficacy of the novel risk based biomarker enhanced disposition. Results: The novel disposition criteria considered 14 patients suitable for outpatient treatment compared to 11 in the current disposition (p = 0.5). It detected 7 patients to be best treated outside the hospital for nursing reasons, while the current disposition detected only 1 patient requiring geriatric care (p = 0.09). Further, it decreased regular hospitalizations considerably (32 vs. 64, p 0.001). Conclusions: The novel risk based biomarker enhanced disposition is an objective, safe and probably more efficient disposition system to identify outpatient treatment options than the current practice at the University Hospital of Basel.展开更多
Curb detection provides road boundary information and is important to road detection.However,curb detection is challenging due to the problems such as various curb shapes,colour,discontinuity.In this work,a novel lear...Curb detection provides road boundary information and is important to road detection.However,curb detection is challenging due to the problems such as various curb shapes,colour,discontinuity.In this work,a novel learning-based method for curb detection is proposed using Lidar point clouds,considering that Lidars are not sensitive to illumination and are relatively stable to weather conditions.A deep neural network,named EdgeNet,is constructed and trained,which handles point clouds in an end-to-end way.After EdgeNet is properly trained,curb points are then segmented in the neural network output.In order to train,a curb point annotation algorithm is also designed to generate training dataset.The curb detection method works well with different road scenarios including intersections.The experimental results validate the effectiveness and robustness of this curb detection method.展开更多
Curb detection is an important research topic in the unmanned ground robot.In this paper,a novel curb detection method using a 2D laser range finder in an urban environment was presented.In the proposed method,firstly...Curb detection is an important research topic in the unmanned ground robot.In this paper,a novel curb detection method using a 2D laser range finder in an urban environment was presented.In the proposed method,firstly,2D sequential laser range finder data were aligned using a Dead-Reckoning(DR) and GPS localization method based on extended Kalman filter.Secondly,curb points were extracted from multi-frame laser data based on spatial-temporal correlation analysis.Finally,the straight and curved curbs were detected by coordinate axis conversion least square linear fitting method and piecewise weighted least square fitting model respectively.The proposed method can detect both raised and sunken curbs robustly in campus environment.The proposed method has been verified in a real robot platform.展开更多
The debate about climate change is highly politicized.Not everyone is convinced that CO_(2)emissions are worth curbing despite seemingly irrefutable evidence in the IPCC’s latest report.[1]Some have vested interests ...The debate about climate change is highly politicized.Not everyone is convinced that CO_(2)emissions are worth curbing despite seemingly irrefutable evidence in the IPCC’s latest report.[1]Some have vested interests in exploiting fossil fuels while others think alternative,cheaper solutions can be found.Countries that have shifted from manufacturing to service-based economies will find it easier to decarbonize.Other countries with relatively low carbon emissions per capita but large populations believe it is unfair that they should have to bear heavy costs of decarbonization to solve a problem that wealthier countries have created.展开更多
In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain ...In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain value abruptly, the charging current in the circuit is very large at the rising and falling edges. This large charging current makes measurement of the actual emissive current from the cathode difficult, constitutes a threat to the components in the circuit and causes attenuation of the emissive current within the pulse. To alleviate these drawbacks, trapezoid voltage pulses, whose rising edges are extended dramatically in comparison with square voltage pulses, are employed to extract the field emission. Under a trapezoid voltage pulse, the charging current is clearly lowered as expected. Furthermore, the heat generated by the charging current under the trapezoid voltage pulse is much smaller than that under the square voltage pulse. Hence the emissive current does not show any attenuation within the pulse. Finally, the average emissive currents are found to decrease with the repetition frequency of the pulses.展开更多
China’s government should continue taking measuresto prevent "structural price rises" from becoming "obviousinflation", said Wang Yiming, an expert from the
Recently, a restriction rule on car ownership in Hangzhou, capital city of east China＇s Zhejiang Province, raised widespread controversy among Chinese citizens. On March 25, the local government announced a car purch...Recently, a restriction rule on car ownership in Hangzhou, capital city of east China＇s Zhejiang Province, raised widespread controversy among Chinese citizens. On March 25, the local government announced a car purchase restriction and implemented it from the next day onwards,making it the sixth Chinese city to clamp down on car ownership. According to the local authority, the regulation aims at easing traffic congestion and combating air pollution.展开更多
文摘目的比较CURB一65评分和强化CURB评分对老年重症社区获得性肺炎（severe community acquired pneumonia，SCAP）预后的临床预测价值。方法回顾性分析2009—12—2015-07入住我院急诊科、呼吸内科以及老年呼吸内科的87例老年SCAP相关临床资料，分别统计每例患者的CURB-65评分、强化CURB评分，以患者28d预后为临床观察终点，绘制受试者工作特征（receiver operator characteristic，ROC）曲线，通过比较曲线下面积（area under the curve，AUC）分析两种评分工具对老年SCAP预后的预测价值。结果87例患者CURB一65评分为3（2—3）分，强化CURB评分为11（10～12）分。死亡组中CURB-65评分和强化CURB评分均明显高于存活组，差异有统计学意义（P〈0．05）。强化CURB评分AUC为0．722，最佳截断值为12，敏感度为58．82％，特异度为69．81％，P=0．0001；CURB-65评分AUC为0．660，最佳截断值为3，敏感度为73．53％，特异度为49．06％，P=0．0091。强化CURB评分AUC大于CURB-65评分，差异有统计学意义（0．722vs．0．660，Z=2．176，P=0．029）。结论CURB-65评分和强化CURB评分均可预测老年SCAP预后，强化CURB评分预测价值高于CURB-65评分，且其特异度高于CURB-65评分。
文摘Background: Despiteits recommendation in management guide lines for community acquired pneumonia (CAP), the CURB65 score is frequently not followed for disposition decisions in clinical routine. We therefore proposed an improved CURB65 A score, supplemented by proadre nome dull in (ProADM) levels for patients with CAP and other lower respiratory tract infections (LRTIs). In this study, we vali dated this risk based biomarker enhanced disposition in patients with LRTIs presenting to the emergency department of the University Hospital of Basel. Methods: In this prospective observational cohort study of 85 patients presenting with LRTIs, site of care was decided by the physicians in charge according to their judgement. Retro spectively the CURB65 A score was calculated and a virtual disposition assigned. This was compared with the existing disposition in order to identify efficacy of the novel risk based biomarker enhanced disposition. Results: The novel disposition criteria considered 14 patients suitable for outpatient treatment compared to 11 in the current disposition (p = 0.5). It detected 7 patients to be best treated outside the hospital for nursing reasons, while the current disposition detected only 1 patient requiring geriatric care (p = 0.09). Further, it decreased regular hospitalizations considerably (32 vs. 64, p 0.001). Conclusions: The novel risk based biomarker enhanced disposition is an objective, safe and probably more efficient disposition system to identify outpatient treatment options than the current practice at the University Hospital of Basel.
基金Supported by the National Natural Science Foundation of China (No.51875331)。
文摘Curb detection provides road boundary information and is important to road detection.However,curb detection is challenging due to the problems such as various curb shapes,colour,discontinuity.In this work,a novel learning-based method for curb detection is proposed using Lidar point clouds,considering that Lidars are not sensitive to illumination and are relatively stable to weather conditions.A deep neural network,named EdgeNet,is constructed and trained,which handles point clouds in an end-to-end way.After EdgeNet is properly trained,curb points are then segmented in the neural network output.In order to train,a curb point annotation algorithm is also designed to generate training dataset.The curb detection method works well with different road scenarios including intersections.The experimental results validate the effectiveness and robustness of this curb detection method.
基金National Natural Science Foundation of China(No.61603184)the Key Laboratory of Intelligent Perception and Systems for High-Dimensional Information(Nanjing University of Science and Technology),Ministry of Education,China(No.30920140122006)the Fundamental Research Funds for the Central Universities,China(No.30915011321)
文摘Curb detection is an important research topic in the unmanned ground robot.In this paper,a novel curb detection method using a 2D laser range finder in an urban environment was presented.In the proposed method,firstly,2D sequential laser range finder data were aligned using a Dead-Reckoning(DR) and GPS localization method based on extended Kalman filter.Secondly,curb points were extracted from multi-frame laser data based on spatial-temporal correlation analysis.Finally,the straight and curved curbs were detected by coordinate axis conversion least square linear fitting method and piecewise weighted least square fitting model respectively.The proposed method can detect both raised and sunken curbs robustly in campus environment.The proposed method has been verified in a real robot platform.
文摘The debate about climate change is highly politicized.Not everyone is convinced that CO_(2)emissions are worth curbing despite seemingly irrefutable evidence in the IPCC’s latest report.[1]Some have vested interests in exploiting fossil fuels while others think alternative,cheaper solutions can be found.Countries that have shifted from manufacturing to service-based economies will find it easier to decarbonize.Other countries with relatively low carbon emissions per capita but large populations believe it is unfair that they should have to bear heavy costs of decarbonization to solve a problem that wealthier countries have created.
基金Supported by the Natural Science Foundation of Jiangsu Province of China under Grant Nos BK20161243 and BK20161242the National Natural Science Foundation of China under Grant No 61774007
文摘In field emission under a non-dc voltage, a displacement current is inevitable due to charging the cathode–anode condenser. Under an often-used square voltage pulse, in which the voltage rises from zero to a certain value abruptly, the charging current in the circuit is very large at the rising and falling edges. This large charging current makes measurement of the actual emissive current from the cathode difficult, constitutes a threat to the components in the circuit and causes attenuation of the emissive current within the pulse. To alleviate these drawbacks, trapezoid voltage pulses, whose rising edges are extended dramatically in comparison with square voltage pulses, are employed to extract the field emission. Under a trapezoid voltage pulse, the charging current is clearly lowered as expected. Furthermore, the heat generated by the charging current under the trapezoid voltage pulse is much smaller than that under the square voltage pulse. Hence the emissive current does not show any attenuation within the pulse. Finally, the average emissive currents are found to decrease with the repetition frequency of the pulses.
文摘China’s government should continue taking measuresto prevent "structural price rises" from becoming "obviousinflation", said Wang Yiming, an expert from the
文摘Recently, a restriction rule on car ownership in Hangzhou, capital city of east China＇s Zhejiang Province, raised widespread controversy among Chinese citizens. On March 25, the local government announced a car purchase restriction and implemented it from the next day onwards,making it the sixth Chinese city to clamp down on car ownership. According to the local authority, the regulation aims at easing traffic congestion and combating air pollution.
