A new sesquiterpene was isolated from transformation of curdione by cell suspension culture of Platycodon grandiflorum. The structure of the new compound was elucidated on the basis of spectral methods including 2D NMR.
(-)-curdione,the antipode of the antitumor principle of Chinese herb Curcuma aromtica Salisb.was synthesized from(-)-carvone via oxy-Cope rearrangement.This result also confirmed the absolute configuration of natural(...(-)-curdione,the antipode of the antitumor principle of Chinese herb Curcuma aromtica Salisb.was synthesized from(-)-carvone via oxy-Cope rearrangement.This result also confirmed the absolute configuration of natural(+)-curdione.展开更多
基金the National Outstanding Youth Foundation by NNSF of China(39925040)Trans-Century Training Program Foundation for the Talents by the Ministry of Education for financial support
文摘A new sesquiterpene was isolated from transformation of curdione by cell suspension culture of Platycodon grandiflorum. The structure of the new compound was elucidated on the basis of spectral methods including 2D NMR.
文摘(-)-curdione,the antipode of the antitumor principle of Chinese herb Curcuma aromtica Salisb.was synthesized from(-)-carvone via oxy-Cope rearrangement.This result also confirmed the absolute configuration of natural(+)-curdione.
