Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mo...Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mongolian medicine combined with external application for treatment,combination of Mongolian medicine acupuncture therapy and oral administration of Mongolian medicine for treatment,integrated treatment of Mongolian and Western medicine,and combination therapy of Mongolian and traditional Chinese medicine,providing new ideas and choices for clinical research.展开更多
Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie ...Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.展开更多
AIM: To evaluate the association between various lifestyle factors and achalasia risk.METHODS: A population-based case-control study was conducted in Northern Ireland, including n = 151 achalasia cases and n = 117 age...AIM: To evaluate the association between various lifestyle factors and achalasia risk.METHODS: A population-based case-control study was conducted in Northern Ireland, including n = 151 achalasia cases and n = 117 age- and sexmatched controls. Lifestyle factors were assessed via a face-to-face structured interview. The association between achalasia and lifestyle factors was assessed by unconditional logistic regression, to produce odds ratios(OR) and 95% confidence interval(CI).RESULTS: Individuals who had low-class occupations were at the highest risk of achalasia(OR = 1.88, 95%CI: 1.02-3.45), inferring that high-class occupation holders have a reduced risk of achalasia. A history of foreign travel, a lifestyle factor linked to upper socioeconomic class, was also associated with a reduced risk of achalasia(OR = 0.59, 95%CI: 0.35-0.99). Smoking and alcohol consumption carried significantly reduced risks of achalasia, even after adjustment for socio-economic status. The presence of pets in the house was associated with a two-fold increased risk of achalasia(OR = 2.00, 95%CI: 1.17-3.42). Nochildhood household factors were associated with achalasia risk.CONCLUSION: Achalasia is a disease of inequality, and individuals from low socio-economic backgrounds are at highest risk. This does not appear to be due to corresponding alcohol and smoking behaviours. An observed positive association between pet ownership and achalasia risk suggests an interaction between endotoxin and viral infection exposure in achalasia aetiology.展开更多
Objectives: The main aim of the current study is to examine the influence of socio-economic status and environmental factors on serologically diagnosed Japanese encephalitis cases in the state of West Bengal, India du...Objectives: The main aim of the current study is to examine the influence of socio-economic status and environmental factors on serologically diagnosed Japanese encephalitis cases in the state of West Bengal, India during 2005-2010. Materials and methods: A total of 648 blood/CSF specimens were collected and/or referred from the suspected AES cases, admitted in the different medical colleges and hospitals of the state during the year of 2005-2010. These specimens were subjected to JE Mac ELISA to determine the actual JE case amongst these AES. The association of the socio-economic status and environmental factors with the serologically diagnosed JE positive cases was studied by a statistical analysis through Normal Deviate test or Z test. Result: Out of 648 specimens, only 175 (27.0%) specimens were reactive to JE IgM antibody, of which 60.0% were from the male individuals and 40.0% from the female population. Major cases were observed in the age group of 0 - 10 years;followed by 11 - 20 years. Regarding literacy, only 58.3% cases had no education and 41.7% were from the literate with varying level of education, i.e., from primary level to post gra- duate level. A total of 65.7% cases were from low income group where as only 34.3% cases were from high income group. Regarding house type, 62.3% cases lived in mud house and 37.7% cases lived in the brick house. In most of the cases (74.3%), persons were living in close proximity to rice fields/lakes/ponds. 69.7% cases were found to occur in the monsoon and post-monsoon period whereas 30.3% cases were reported in the pre-monsoon period. Conclusion: Our study concludes that socio-economic status and environmental conditions were statistically significant contextual risk factors for serologically diagnosed JE incidences in West Bengal where JE is proved to be endemic in nature and such study constitutes a new report of this kind in the region.展开更多
Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future developmen...Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future development of high-speed rail technology.Design/methodology/approach–This paper elaborates on the demand and significance of developing high-speed maglev technology worldwide and examines the current status and technological maturity of several major high-speed maglev systems globally.Findings–This paper summarizes the challenges in the development of high-speed maglev railways in China.Based on this analysis,it puts forward considerations for future research on high-speed maglev railways.Originality/value–This paper describes the development status and technical maturity of several major high-speed maglev systems in the world for the first time,summarizes the existing problems in the development of China’s high-speed maglev railway and on this basis,puts forward the thinking of the next research of China’s high-speed maglev railway.展开更多
Objectives:The study examined socio-economic status and gender as determinant of dietary practices of senior secondary school students in Edo South Senatorial district for healthy living and sustainability.Methodology...Objectives:The study examined socio-economic status and gender as determinant of dietary practices of senior secondary school students in Edo South Senatorial district for healthy living and sustainability.Methodology:Quasi experimental research design was employed in the study.Three research questions were raised and formulated into hypotheses,tested at 0.05 level of significance.A multistage random sampling technique was used to sample 245 students from two public schools in Oredo local government areas within Edo south senatorial district.Two(2)instruments(questionnaire and achievement test)validated and reliability of 0.64 and 0.84 reliability co-efficient were obtained.The demographic data/SES,dietary practices(DDPSESQ)was used to obtain information on their dietary practices and socio-economic status,while the pictorial nutrition achievement test(PNAT)consisted of the pre-and post-test.The treatment package comprised planned lessons of 40 minutes each for six(6)weeks.The data collected were analyzed using inferential statistics;hypotheses 1 and 2 were tested using the independent t-test while hypothesis 3 was tested using One-Way ANOVA statistics.Findings:The study revealed that there is no significant difference in dietary practices of students of high,medium and low socio-economic status as a result of exposure to pictorial nutrition education.There was no significant difference in dietary practices by gender.The study concluded that socio-economic status does not determine dietary practices of secondary school students for responsible living.展开更多
Every day many students apply for and enroll in language-teaching courses to achieve their aims through learning another language. However, learning another language does not occur identically among all students. Some...Every day many students apply for and enroll in language-teaching courses to achieve their aims through learning another language. However, learning another language does not occur identically among all students. Some students learn a language, even their own mother tongue earlier but some others may need to spend more time acquiring a language. Seeking out for the probable reasons for such a difference, the current study following the constructivist approach to language learning and bearing in mind the role of society and human communities in language learning, was concluded to investigate the probable impact(s) of some social variables (social status, attitudinal and motivational status of learners) on language learning outcomes of Iranian adult learners assessed through a standardized English proficiency test. The findings have revealed that the social milieu in which learners live may play a decisive role as far as learning opportunities, input and resources are concerned.展开更多
In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as...In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as different standard in educational management and requirements, insufficiency of trilingual teachers and unreasonableness in teacher structure, shortage both in the number and characteristics of trilingual teaching materials, lateness in the study on TETAC and insufficiency of study result, and backwardness in teaching approaches and methods, etc.展开更多
The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as governm...The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as government begin to attach importance to it.There is a hospice and palliative care movement now in China.This article gives an overview of the progress and the current status in multiple aspects of hospice and palliative care in China's Mainland,and points out the barriers and challenges for its further development in the future.展开更多
Non-human primates (NHPs) are phylogenetically close to humans, with many similarities in terms of physiology, anatomy, immunology, as well as neurology, all of which make them excellent experimental models for biom...Non-human primates (NHPs) are phylogenetically close to humans, with many similarities in terms of physiology, anatomy, immunology, as well as neurology, all of which make them excellent experimental models for biomedical research. Compared with developed countries in America and Europe, China has relatively rich primate resources and has continually aimed to develop NHPs resources. Currently, China is a leading producer and a major supplier of NHPs on the international market. However, there are some deficiencies in feeding and management that have hampered China's growth in NHP research and materials. Nonetheless, China has recently established a number of primate animal models for human diseases and achieved marked scientific progress on infectious diseases, cardiovascular diseases, endocrine diseases, reproductive diseases, neurological diseases, and ophthalmic diseases, etc. Advances in these fields via NHP models will undoubtedly further promote the development of China's life sciences and pharmaceutical industry, and enhance China's position as a leader in NHP research. This review covers the current status of NHPs in China and other areas, highlighting the latest developments in disease models using NHPs, as well as outlining basic problems and proposing effective to better utilize NHP resources and further foster NHP research in China.展开更多
The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity ...The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity and mortality remain high,and many patients progress to end-stage heart failure.Heart transplantation has become standard treatment for selected patients with end-stage heart failure,though challenges still exist.However,multiple advances over the past few years will improve the survival and quality-of-life of heart transplant recipients.This article elaborates on the specific characteristics of heart transplantation in China,the current issues,development trends,and related experiences with heart transplantation in Wuhan Union Hospital.展开更多
Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improve...Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improvement. Although homology-directed repair(HDR)is a feasible approach to achieve precise gene replacement and base substitution in some plant species, the dominance of the non-homologous end joining pathway and low efficiency of HDR in plant cells have limited its application. Base editing has emerged as an alternative tool to HDR-mediated replacement, facilitating precise editing of plant genome by converting one single base to another in a programmable manner without a doublestranded break and a donor repair template. In this review, we summarize the latest developments in base-editing technologies as well as their underlying mechanisms. We review current applications of these technologies in plant species. Finally, we address the challenges and future perspectives of this emerging technology in plants.展开更多
This paper presented the current status quo of hybrid rice in India from the breeding,seed production and extension and the existing problems and barriers,based on which the corresponding countermeasures were put forw...This paper presented the current status quo of hybrid rice in India from the breeding,seed production and extension and the existing problems and barriers,based on which the corresponding countermeasures were put forward.展开更多
For the purpose of accommodating the relationship between the protection of nature reserve and the development of local society and economy,this paper,taking Dalian Chengshantou Nature Reserve as a study area and PRA ...For the purpose of accommodating the relationship between the protection of nature reserve and the development of local society and economy,this paper,taking Dalian Chengshantou Nature Reserve as a study area and PRA as a main research method,investigated and analyzed the status of social and economical development and the existing problems in the study area. The result shows that: the contradictory between the protection of nature reserve and the local development of social and economical activities are still prominent,and the principle of " integration of protection and reasonable development" proposed by the general plan of nature reserve has not reached the expected result.Therefore,further efforts should be made firstly to accommodating relationship between the protection of nature reserve and the local development activities,secondly to accelerating the development of eco-tourism and the relevant service industries in accordance with the local practical situations,and finally to promoting the sustainable development of both the protection of nature reserve and the local society and economy.展开更多
In recent years,due to regional pollution and deteriorating environment,combined with intense social competition and heavier life pressure,an increasing number of people are affected by lifestyle-related diseases and ...In recent years,due to regional pollution and deteriorating environment,combined with intense social competition and heavier life pressure,an increasing number of people are affected by lifestyle-related diseases and remain in a state of being sub-healthy.Therefore,health issue has been receiving unprecedented attention.展开更多
Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean w...Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean was first introduced to SSA by Chinese traders in the19 th century and was cultivated as an economic crop as early as 1903 in South Africa. In the past four decades, soybean cultivation area and production in SSA has increased exponentially, from about 20,000 ha and 13,000 t in the early 1970 s to 1,500,000 ha and2,300,000 t in 2016. Soybean yield has been stagnant in SSA for decades at about 1.1 t ha^(-1),much lower than the world average, representing one of the most challenging issues in the soybean industry in SSA. The low soybean yield in SSA can be attributed to the use of poorperforming varieties and to the limited application of fertilizers and rhizobial inoculants in soils with no history of soybean production. South Africa, Nigeria, Zambia, and Uganda are the leading soybean producers in SSA. Soybean research in SSA is conducted by international and national research institutions, including IITA, national soybean improvement programs, universities, and the private sector. Between 1970 and 2011, 195 soybean varieties were released by IITA, private breeders, and national soybean improvement programs in SSA. This paper reviews the history and current state of soybean production and of the utilization and adoption of tropical varieties in SSA, addresses the major soybean yield-limiting factors across the region, and discusses the potential of the soybean industry in SSA. It also highlights soybean improvement efforts and lessons learned from previous soybean improvement efforts and the current progress of some national soybean improvement programs in SSA. Opportunities for scaling up tropical soybean as a major crop across SSA countries are promising.展开更多
Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsi...Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsible for the identification, diagnosis, treatment, supervision, and management of TB patients .展开更多
The concept, pathways and the present status of biological invasion in China are reviewed in the paper, and the effect of biological invasion on ecological security is also introduced. On this basis, the measures such...The concept, pathways and the present status of biological invasion in China are reviewed in the paper, and the effect of biological invasion on ecological security is also introduced. On this basis, the measures such as establishing early-warning mechanism, strengthening the management of invasive species and quarantine of alien species, establishing scientific system of introduction and improving people awareness are proposed to control the invasion of alien species, so as to ensure the ecological security in china.展开更多
Latest advances in network sensor technology and state of the art of mobile robotics and artificial intelligence research can be applied to develop autonomous and distributed monitoring systems. Intelligent Space (iS...Latest advances in network sensor technology and state of the art of mobile robotics and artificial intelligence research can be applied to develop autonomous and distributed monitoring systems. Intelligent Space (iSpace) is an environmental system, which is able to support human in informative and physical ways. iSpace observing the space with distributed sensors, extracts useful information from the obtained data and provides various services to users. This means that essential functions of iSpace are "observation", "recognition" and "actuation." In this paper, we focus on the observation function of iSpace. And we describe observation systems to get information of both human and mobile agents in the space to show new results.展开更多
s: The current status of AEE in Hunan Province is introduced in brief. The reasons why the AEE was polluted and destroyed are analyzed; the countermeasures for improving AEE are brought forward.
文摘Through literature and clinical research,the current status of Mongolian medicine treatment for breast hyperplasia is discussed,such as oral administration of Mongolian medicine for treatment,oral administration of Mongolian medicine combined with external application for treatment,combination of Mongolian medicine acupuncture therapy and oral administration of Mongolian medicine for treatment,integrated treatment of Mongolian and Western medicine,and combination therapy of Mongolian and traditional Chinese medicine,providing new ideas and choices for clinical research.
基金Guangzhou Planned Project of Science and Technology,No.2023A04J0612。
文摘Metabolic-associated fatty liver disease(MAFLD)is one of the most common chronic liver diseases worldwide.In recent years,the occurrence rate of MAFLD has been on the rise,mainly due to lifestyle changes,high-calorie diets,and imbalanced dietary structures,thereby posing a threat to human health and creating heavy social and economic burdens.With the development of 16S sequencing and integrated multi-omics analysis,the role of the gut microbiota(GM)and its metabolites in MAFLD has been further recognized.The GM plays a role in digestion,energy metabolism,vitamin synthesis,the prevention of pathogenic bacteria colonisation,and immunoregulation.The gut-liver axis is one of the vital links between the GM and the liver.Toxic substances in the intestine can enter the liver through the portal vascular system when the intestinal barrier is severely damaged.The liver also influences the GM in various ways,such as bile acid circulation.The gut-liver axis is essential in maintaining the body’s normal physiological state and plays a role in the onset and prognosis of many diseases,including MAFLD.This article reviews the status of the GM and MAFLD and summarizes the GM characteristics in MAFLD.The relationship between the GM and MAFLD is discussed in terms of bile acid circulation,energy metabolism,micronutrients,and signalling pathways.Current MAFLD treat ments targeting the GM are also listed.
文摘AIM: To evaluate the association between various lifestyle factors and achalasia risk.METHODS: A population-based case-control study was conducted in Northern Ireland, including n = 151 achalasia cases and n = 117 age- and sexmatched controls. Lifestyle factors were assessed via a face-to-face structured interview. The association between achalasia and lifestyle factors was assessed by unconditional logistic regression, to produce odds ratios(OR) and 95% confidence interval(CI).RESULTS: Individuals who had low-class occupations were at the highest risk of achalasia(OR = 1.88, 95%CI: 1.02-3.45), inferring that high-class occupation holders have a reduced risk of achalasia. A history of foreign travel, a lifestyle factor linked to upper socioeconomic class, was also associated with a reduced risk of achalasia(OR = 0.59, 95%CI: 0.35-0.99). Smoking and alcohol consumption carried significantly reduced risks of achalasia, even after adjustment for socio-economic status. The presence of pets in the house was associated with a two-fold increased risk of achalasia(OR = 2.00, 95%CI: 1.17-3.42). Nochildhood household factors were associated with achalasia risk.CONCLUSION: Achalasia is a disease of inequality, and individuals from low socio-economic backgrounds are at highest risk. This does not appear to be due to corresponding alcohol and smoking behaviours. An observed positive association between pet ownership and achalasia risk suggests an interaction between endotoxin and viral infection exposure in achalasia aetiology.
文摘Objectives: The main aim of the current study is to examine the influence of socio-economic status and environmental factors on serologically diagnosed Japanese encephalitis cases in the state of West Bengal, India during 2005-2010. Materials and methods: A total of 648 blood/CSF specimens were collected and/or referred from the suspected AES cases, admitted in the different medical colleges and hospitals of the state during the year of 2005-2010. These specimens were subjected to JE Mac ELISA to determine the actual JE case amongst these AES. The association of the socio-economic status and environmental factors with the serologically diagnosed JE positive cases was studied by a statistical analysis through Normal Deviate test or Z test. Result: Out of 648 specimens, only 175 (27.0%) specimens were reactive to JE IgM antibody, of which 60.0% were from the male individuals and 40.0% from the female population. Major cases were observed in the age group of 0 - 10 years;followed by 11 - 20 years. Regarding literacy, only 58.3% cases had no education and 41.7% were from the literate with varying level of education, i.e., from primary level to post gra- duate level. A total of 65.7% cases were from low income group where as only 34.3% cases were from high income group. Regarding house type, 62.3% cases lived in mud house and 37.7% cases lived in the brick house. In most of the cases (74.3%), persons were living in close proximity to rice fields/lakes/ponds. 69.7% cases were found to occur in the monsoon and post-monsoon period whereas 30.3% cases were reported in the pre-monsoon period. Conclusion: Our study concludes that socio-economic status and environmental conditions were statistically significant contextual risk factors for serologically diagnosed JE incidences in West Bengal where JE is proved to be endemic in nature and such study constitutes a new report of this kind in the region.
基金This paper was supported by the funding of Strategic research and consulting project of Chinese Academy of Engineering(Grant No.2022-XBZD-20).
文摘Purpose–High-speed maglev technology can address the issues of adhesion,friction,vibration and highspeed current collection in traditional wheel-rail systems,making it an important direction for the future development of high-speed rail technology.Design/methodology/approach–This paper elaborates on the demand and significance of developing high-speed maglev technology worldwide and examines the current status and technological maturity of several major high-speed maglev systems globally.Findings–This paper summarizes the challenges in the development of high-speed maglev railways in China.Based on this analysis,it puts forward considerations for future research on high-speed maglev railways.Originality/value–This paper describes the development status and technical maturity of several major high-speed maglev systems in the world for the first time,summarizes the existing problems in the development of China’s high-speed maglev railway and on this basis,puts forward the thinking of the next research of China’s high-speed maglev railway.
文摘Objectives:The study examined socio-economic status and gender as determinant of dietary practices of senior secondary school students in Edo South Senatorial district for healthy living and sustainability.Methodology:Quasi experimental research design was employed in the study.Three research questions were raised and formulated into hypotheses,tested at 0.05 level of significance.A multistage random sampling technique was used to sample 245 students from two public schools in Oredo local government areas within Edo south senatorial district.Two(2)instruments(questionnaire and achievement test)validated and reliability of 0.64 and 0.84 reliability co-efficient were obtained.The demographic data/SES,dietary practices(DDPSESQ)was used to obtain information on their dietary practices and socio-economic status,while the pictorial nutrition achievement test(PNAT)consisted of the pre-and post-test.The treatment package comprised planned lessons of 40 minutes each for six(6)weeks.The data collected were analyzed using inferential statistics;hypotheses 1 and 2 were tested using the independent t-test while hypothesis 3 was tested using One-Way ANOVA statistics.Findings:The study revealed that there is no significant difference in dietary practices of students of high,medium and low socio-economic status as a result of exposure to pictorial nutrition education.There was no significant difference in dietary practices by gender.The study concluded that socio-economic status does not determine dietary practices of secondary school students for responsible living.
文摘Every day many students apply for and enroll in language-teaching courses to achieve their aims through learning another language. However, learning another language does not occur identically among all students. Some students learn a language, even their own mother tongue earlier but some others may need to spend more time acquiring a language. Seeking out for the probable reasons for such a difference, the current study following the constructivist approach to language learning and bearing in mind the role of society and human communities in language learning, was concluded to investigate the probable impact(s) of some social variables (social status, attitudinal and motivational status of learners) on language learning outcomes of Iranian adult learners assessed through a standardized English proficiency test. The findings have revealed that the social milieu in which learners live may play a decisive role as far as learning opportunities, input and resources are concerned.
文摘In China trilingual education, as an important part of Chinese national education, is likely to be not only required, but essential. However, among the tremendous achievements, there still exist some problems, such as different standard in educational management and requirements, insufficiency of trilingual teachers and unreasonableness in teacher structure, shortage both in the number and characteristics of trilingual teaching materials, lateness in the study on TETAC and insufficiency of study result, and backwardness in teaching approaches and methods, etc.
基金supported by the Educational Reform Project of Peking Union Medical College(2015zlgc0120)
文摘The concept of End-of-Life Care(EOLC)came into China in the late1980s.However,hospice and palliative care in medical practice develope slowly.In recent years,profesionals,patients and their families,as well as government begin to attach importance to it.There is a hospice and palliative care movement now in China.This article gives an overview of the progress and the current status in multiple aspects of hospice and palliative care in China's Mainland,and points out the barriers and challenges for its further development in the future.
基金supported by the National Natural Science Foundation of China(81172876,81273251,U1202228,81471620)the National Special Science Research Program of China(2012CBA01305)+1 种基金the National Science and Technology Major Project(2013ZX10001-002,2012ZX10001-007)the Knowledge Innovation Program of CAS(KSCX2-EW-R-13,KJZD-EW-L10-02)
文摘Non-human primates (NHPs) are phylogenetically close to humans, with many similarities in terms of physiology, anatomy, immunology, as well as neurology, all of which make them excellent experimental models for biomedical research. Compared with developed countries in America and Europe, China has relatively rich primate resources and has continually aimed to develop NHPs resources. Currently, China is a leading producer and a major supplier of NHPs on the international market. However, there are some deficiencies in feeding and management that have hampered China's growth in NHP research and materials. Nonetheless, China has recently established a number of primate animal models for human diseases and achieved marked scientific progress on infectious diseases, cardiovascular diseases, endocrine diseases, reproductive diseases, neurological diseases, and ophthalmic diseases, etc. Advances in these fields via NHP models will undoubtedly further promote the development of China's life sciences and pharmaceutical industry, and enhance China's position as a leader in NHP research. This review covers the current status of NHPs in China and other areas, highlighting the latest developments in disease models using NHPs, as well as outlining basic problems and proposing effective to better utilize NHP resources and further foster NHP research in China.
文摘The purpose of this review is to provide a comprehensive update on recent advances in heart transplantation in China.Despite advances in pharmacologic and device treatment of chronic heart failure,long-term morbidity and mortality remain high,and many patients progress to end-stage heart failure.Heart transplantation has become standard treatment for selected patients with end-stage heart failure,though challenges still exist.However,multiple advances over the past few years will improve the survival and quality-of-life of heart transplant recipients.This article elaborates on the specific characteristics of heart transplantation in China,the current issues,development trends,and related experiences with heart transplantation in Wuhan Union Hospital.
基金partly funded by the Transgenesis Initiative Project supported by the Ministry of Agriculture and Rural Affairs of China(2019ZX08010001,2019ZX08010003)the Central Non-Profit Fundamental Research Funding supported by the Institute of Crop Sciences,Chinese Academy of Agricultural Sciences(S2018QY05)。
文摘Genome editing technologies have revolutionized the field of plant science by enabling targeted modification of plant genomes and are emerging as powerful tools for both plant gene functional analyses and crop improvement. Although homology-directed repair(HDR)is a feasible approach to achieve precise gene replacement and base substitution in some plant species, the dominance of the non-homologous end joining pathway and low efficiency of HDR in plant cells have limited its application. Base editing has emerged as an alternative tool to HDR-mediated replacement, facilitating precise editing of plant genome by converting one single base to another in a programmable manner without a doublestranded break and a donor repair template. In this review, we summarize the latest developments in base-editing technologies as well as their underlying mechanisms. We review current applications of these technologies in plant species. Finally, we address the challenges and future perspectives of this emerging technology in plants.
基金Supported by the Scientific Cooperation Project of the Ministry of Science and Technology Innovation of Malaysia (07-04-01PB015)~~
文摘This paper presented the current status quo of hybrid rice in India from the breeding,seed production and extension and the existing problems and barriers,based on which the corresponding countermeasures were put forward.
基金Supported by Commissioned Project of Dalian Chengshantou Coastal Landform National Nature Reserve Administration
文摘For the purpose of accommodating the relationship between the protection of nature reserve and the development of local society and economy,this paper,taking Dalian Chengshantou Nature Reserve as a study area and PRA as a main research method,investigated and analyzed the status of social and economical development and the existing problems in the study area. The result shows that: the contradictory between the protection of nature reserve and the local development of social and economical activities are still prominent,and the principle of " integration of protection and reasonable development" proposed by the general plan of nature reserve has not reached the expected result.Therefore,further efforts should be made firstly to accommodating relationship between the protection of nature reserve and the local development activities,secondly to accelerating the development of eco-tourism and the relevant service industries in accordance with the local practical situations,and finally to promoting the sustainable development of both the protection of nature reserve and the local society and economy.
基金supported by funds from the National Natural Science Foundation of China[31670701]Health Bureau of Zhejiang Province[2016KYB005]
文摘In recent years,due to regional pollution and deteriorating environment,combined with intense social competition and heavier life pressure,an increasing number of people are affected by lifestyle-related diseases and remain in a state of being sub-healthy.Therefore,health issue has been receiving unprecedented attention.
基金supported by the Agricultural Science and Technology Innovation Program of CAAS and China Agriculture Research System (CARS-04) awarded to T.Han of CAAS and S.E.Ibrahim of Agricultural Research Corporation(ARC)Soybean Research Program,Wad Medani,Sudan
文摘Soybean(Glycine max(L.) Merr.) is a non-native and non-staple crop in sub-Saharan Africa(SSA) with potential to be a commercial crop owing to its wide range of uses as food, feed,and industrial raw material. Soybean was first introduced to SSA by Chinese traders in the19 th century and was cultivated as an economic crop as early as 1903 in South Africa. In the past four decades, soybean cultivation area and production in SSA has increased exponentially, from about 20,000 ha and 13,000 t in the early 1970 s to 1,500,000 ha and2,300,000 t in 2016. Soybean yield has been stagnant in SSA for decades at about 1.1 t ha^(-1),much lower than the world average, representing one of the most challenging issues in the soybean industry in SSA. The low soybean yield in SSA can be attributed to the use of poorperforming varieties and to the limited application of fertilizers and rhizobial inoculants in soils with no history of soybean production. South Africa, Nigeria, Zambia, and Uganda are the leading soybean producers in SSA. Soybean research in SSA is conducted by international and national research institutions, including IITA, national soybean improvement programs, universities, and the private sector. Between 1970 and 2011, 195 soybean varieties were released by IITA, private breeders, and national soybean improvement programs in SSA. This paper reviews the history and current state of soybean production and of the utilization and adoption of tropical varieties in SSA, addresses the major soybean yield-limiting factors across the region, and discusses the potential of the soybean industry in SSA. It also highlights soybean improvement efforts and lessons learned from previous soybean improvement efforts and the current progress of some national soybean improvement programs in SSA. Opportunities for scaling up tropical soybean as a major crop across SSA countries are promising.
基金funded by the China-Gates Foundation TB Control Project(Phase Ⅱ)(51914)
文摘Health care facilities are a high-risk environment for generating and spreading respiratory infectious diseases such as tuberculosis (TB). The TB prevention and treatment staff in health care facilities are responsible for the identification, diagnosis, treatment, supervision, and management of TB patients .
文摘The concept, pathways and the present status of biological invasion in China are reviewed in the paper, and the effect of biological invasion on ecological security is also introduced. On this basis, the measures such as establishing early-warning mechanism, strengthening the management of invasive species and quarantine of alien species, establishing scientific system of introduction and improving people awareness are proposed to control the invasion of alien species, so as to ensure the ecological security in china.
文摘Latest advances in network sensor technology and state of the art of mobile robotics and artificial intelligence research can be applied to develop autonomous and distributed monitoring systems. Intelligent Space (iSpace) is an environmental system, which is able to support human in informative and physical ways. iSpace observing the space with distributed sensors, extracts useful information from the obtained data and provides various services to users. This means that essential functions of iSpace are "observation", "recognition" and "actuation." In this paper, we focus on the observation function of iSpace. And we describe observation systems to get information of both human and mobile agents in the space to show new results.
文摘s: The current status of AEE in Hunan Province is introduced in brief. The reasons why the AEE was polluted and destroyed are analyzed; the countermeasures for improving AEE are brought forward.