Let (?) be a formation locally defined by f(P), G ∈ (?) and A a ZG-module, where p ∈ π = { all primes and symbol ∞}. Then a p-main-factor U/V of G is said to be (?)-central in G if G/CG(U/V) ∈f(p). In this paper,...Let (?) be a formation locally defined by f(P), G ∈ (?) and A a ZG-module, where p ∈ π = { all primes and symbol ∞}. Then a p-main-factor U/V of G is said to be (?)-central in G if G/CG(U/V) ∈f(p). In this paper, we have proved that: let (?) be a locally defined formation consisting of locally soluble groups, G a hyper-(cyclic or finite) locally soluble group and A an artinian ZG-module with all irreducible ZG-factors of A being finite; if G ∈ (?), f(∞) ≡ f(p) . f(p)≠φ for each p ∈ π, A has an (?)-decomposition.展开更多
Interferon regulatory factor 7 plays a crucial role in the innate immune response.However,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains unknown.Here we report...Interferon regulatory factor 7 plays a crucial role in the innate immune response.However,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains unknown.Here we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial cells.Both the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 phenotype.In addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and YM1.Taken together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.展开更多
为了从具有周期性的纱线毛羽H值数据中提取有代表性的毛羽H值周期模式(即周期时间或周期数据长度上毛羽数据的变化),使用动态时间规整(dynamic time warping,DTW)算法识别毛羽H值的周期模式,同时使用局部暴力搜索和剪枝算法对DTW算法进...为了从具有周期性的纱线毛羽H值数据中提取有代表性的毛羽H值周期模式(即周期时间或周期数据长度上毛羽数据的变化),使用动态时间规整(dynamic time warping,DTW)算法识别毛羽H值的周期模式,同时使用局部暴力搜索和剪枝算法对DTW算法进行优化。从14台细纱机上采集棉纺与混纺纱试样,利用乌斯特条干仪测得的毛羽H值计算理论周期及任意两周期模式间的DTW距离。结果表明:当DTW距离矩阵中出现显著不同于其他周期模式的现象时,该设备可能存在异常或故障;在设定的试验条件下,不同品种纱线的理论周期和实际周期存在差异,平均相差0.48 m,由此可根据实际周期反向推导纱线每分钟的实际卷绕长度。展开更多
Hot corrosion is a serious problem in aircraft, marine, industrial and land-base gas turbines. To obviate these problems, superalloy superfer 800H (Midhani grade) is one of the prominent materials for the high tempera...Hot corrosion is a serious problem in aircraft, marine, industrial and land-base gas turbines. To obviate these problems, superalloy superfer 800H (Midhani grade) is one of the prominent materials for the high temperature applications. The present work investigates hot corrosion behaviour of superfer 800H exposed to two different molten salt environments Na2SO4 + 60% V2O5 and Na2SO4 + 5% V2O5 + 5% NaCl respectively, at 900oC under cyclic conditions. The weight change measurements made on during the experiments are used to determine the kinetics of hot corrosion. It is observed that the formation of scale rich in Cr2O3, NiO and spinel NiCr2O4 has contributed for the better hot corrosion resistance of superfer 800H. Inspection for 10, 20, 35 and 50 cycles reveals that after 10 cycles Crack has been initiated in the scale and it is clearly visible in the presence of NaCl salt. On subsequent cycles, crack propagates perpendicular to surface and as it encounters inclusions.展开更多
AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally i...AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally induced surface damage, i. e., thermal fatigne,is believed to be controlled by the magnitude of the imposed cyclic strain. The thermal fatigue on the surface of hot working die, which is responsible to the initiation of the cracks, is reported to result in more than 80 % of the failure of dies.展开更多
The title complex [Cu（L1）（L2）（H2O）]·H2O（1,HL1 = N-（imino（pyridin-2-yl）me-thyl）picolinamidine）,HL2 = salicylic acid） has been obtained by volatilization method with L1 prepared from 2,4,6-tripyridyl-1...The title complex [Cu（L1）（L2）（H2O）]·H2O（1,HL1 = N-（imino（pyridin-2-yl）me-thyl）picolinamidine）,HL2 = salicylic acid） has been obtained by volatilization method with L1 prepared from 2,4,6-tripyridyl-1,3,5-triazine in situ.1 was fully characterized by single-crystal X-ray diffraction,elemental analysis and FT-IR.This complex exhibits a three-dimensional frame-work constructed through hydrogen bonding and C-H···π stacking interactions.The cyclic voltametric behavior of complex 1 was also investigated.1 belongs to the monoclinic system,space group P21/c with a = 15.112（5）,b = 7.115（2）,c = 19.899（6） ,β = 112.32°,V = 1979.4（11） 3,Mr = 460.94,Dc = 1.540 g/cm3,F（000） = 948,μ = 1.146 mm-1,Z = 4,the final R = 0.0612 and wR = 0.1813 for 2510 observed reflections with I 2σ（I）.展开更多
Two complexes, [Cu2（Htdb）4（H2O）2] （1） and [Cd（bipy）2（Hmcmbc）2] （2） （H2tdb = 2,2-thiodibenzoic acid, H2mcmbc = m-（carboxyl-methyloxy）-benzenecarboxylic acid, bipy = 4,4＇-bipyridine）, have been prepared...Two complexes, [Cu2（Htdb）4（H2O）2] （1） and [Cd（bipy）2（Hmcmbc）2] （2） （H2tdb = 2,2-thiodibenzoic acid, H2mcmbc = m-（carboxyl-methyloxy）-benzenecarboxylic acid, bipy = 4,4＇-bipyridine）, have been prepared, and were characterized by elemental analysis, FT-IR and single-crystal X-ray diffraction. Structures indicate that complex 1 is a single molecule, and 2 is a one-dimensional chain. Their two-and three-dimensional frameworks are constructed through hydrogen bonding, π…π or C–H…π stacking, and such other weak interactions. The cyclic voltametric behavior of complex 1 and luminescence property of complex 2 were investigated. 1 belongs to the triclinic system, space group P with a = 7.8607（6）, b = 11.7619（9）, c = 15.3481（12） , α = 109.3670（10）, β = 92.4420（10）, γ = 92.0450（10）°, V = 1335.65（18） 3, Mr = 1256.26, Dc = 1.5619（2） g/cm3, F（000） = 642, μ = 1.029 mm–1, Z = 1, the final R = 0.0289 and wR = 0.0763 for 5199 observed reflections with I 2σ（I）. Complex 2 crystallizes in triclinic, space group P with a = 9.6378（10）, b = 9.7508（10）, c = 19.055（2） , α = 88.7020（10）, β = 80.5260（10）, γ = 69.2000（10）o, V = 1649.9（3） 3, Mr = 815.07, Dc = 1.641 g/cm3, μ = 0.732 mm-1, F（000） = 828, Z = 2, the final R = 0.0511 and wR = 0.1149 for 4729 observed reflections （I 2σ（I））.展开更多
文摘Let (?) be a formation locally defined by f(P), G ∈ (?) and A a ZG-module, where p ∈ π = { all primes and symbol ∞}. Then a p-main-factor U/V of G is said to be (?)-central in G if G/CG(U/V) ∈f(p). In this paper, we have proved that: let (?) be a locally defined formation consisting of locally soluble groups, G a hyper-(cyclic or finite) locally soluble group and A an artinian ZG-module with all irreducible ZG-factors of A being finite; if G ∈ (?), f(∞) ≡ f(p) . f(p)≠φ for each p ∈ π, A has an (?)-decomposition.
基金supported by the National Natural Science Foundation of China,Nos.82171429,81771384a grant from Wuxi Municipal Health Commission,No.1286010241190480(all to YS)。
文摘Interferon regulatory factor 7 plays a crucial role in the innate immune response.However,whether interferon regulatory factor 7-mediated signaling contributes to Parkinson's disease remains unknown.Here we report that interferon regulatory factor 7 is markedly up-regulated in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease and co-localizes with microglial cells.Both the selective cyclic guanosine monophosphate adenosine monophosphate synthase inhibitor RU.521 and the stimulator of interferon genes inhibitor H151 effectively suppressed interferon regulatory factor 7 activation in BV2 microglia exposed to 1-methyl-4-phenylpyridinium and inhibited transformation of mouse BV2 microglia into the neurotoxic M1 phenotype.In addition,si RNA-mediated knockdown of interferon regulatory factor 7 expression in BV2 microglia reduced the expression of inducible nitric oxide synthase,tumor necrosis factorα,CD16,CD32,and CD86 and increased the expression of the anti-inflammatory markers ARG1 and YM1.Taken together,our findings indicate that the cyclic guanosine monophosphate adenosine monophosphate synthase-stimulator of interferon genes-interferon regulatory factor 7 pathway plays a crucial role in the pathogenesis of Parkinson's disease.
文摘为了从具有周期性的纱线毛羽H值数据中提取有代表性的毛羽H值周期模式(即周期时间或周期数据长度上毛羽数据的变化),使用动态时间规整(dynamic time warping,DTW)算法识别毛羽H值的周期模式,同时使用局部暴力搜索和剪枝算法对DTW算法进行优化。从14台细纱机上采集棉纺与混纺纱试样,利用乌斯特条干仪测得的毛羽H值计算理论周期及任意两周期模式间的DTW距离。结果表明:当DTW距离矩阵中出现显著不同于其他周期模式的现象时,该设备可能存在异常或故障;在设定的试验条件下,不同品种纱线的理论周期和实际周期存在差异,平均相差0.48 m,由此可根据实际周期反向推导纱线每分钟的实际卷绕长度。
文摘Hot corrosion is a serious problem in aircraft, marine, industrial and land-base gas turbines. To obviate these problems, superalloy superfer 800H (Midhani grade) is one of the prominent materials for the high temperature applications. The present work investigates hot corrosion behaviour of superfer 800H exposed to two different molten salt environments Na2SO4 + 60% V2O5 and Na2SO4 + 5% V2O5 + 5% NaCl respectively, at 900oC under cyclic conditions. The weight change measurements made on during the experiments are used to determine the kinetics of hot corrosion. It is observed that the formation of scale rich in Cr2O3, NiO and spinel NiCr2O4 has contributed for the better hot corrosion resistance of superfer 800H. Inspection for 10, 20, 35 and 50 cycles reveals that after 10 cycles Crack has been initiated in the scale and it is clearly visible in the presence of NaCl salt. On subsequent cycles, crack propagates perpendicular to surface and as it encounters inclusions.
文摘AISI H13 hot work tool steel is widely used for hot forging, hot-extrusion and die-casting because of its high temperature strength, impact toughness, heat checking resistance and wear resistance, etc. The thermally induced surface damage, i. e., thermal fatigne,is believed to be controlled by the magnitude of the imposed cyclic strain. The thermal fatigue on the surface of hot working die, which is responsible to the initiation of the cracks, is reported to result in more than 80 % of the failure of dies.
基金supported by the University Science Foundation of Anhui Province (No.KJ2009B104)the Applied Chemistry Key Constructing Subject of Anhui Province (No.200802187C)
文摘The title complex [Cu（L1）（L2）（H2O）]·H2O（1,HL1 = N-（imino（pyridin-2-yl）me-thyl）picolinamidine）,HL2 = salicylic acid） has been obtained by volatilization method with L1 prepared from 2,4,6-tripyridyl-1,3,5-triazine in situ.1 was fully characterized by single-crystal X-ray diffraction,elemental analysis and FT-IR.This complex exhibits a three-dimensional frame-work constructed through hydrogen bonding and C-H···π stacking interactions.The cyclic voltametric behavior of complex 1 was also investigated.1 belongs to the monoclinic system,space group P21/c with a = 15.112（5）,b = 7.115（2）,c = 19.899（6） ,β = 112.32°,V = 1979.4（11） 3,Mr = 460.94,Dc = 1.540 g/cm3,F（000） = 948,μ = 1.146 mm-1,Z = 4,the final R = 0.0612 and wR = 0.1813 for 2510 observed reflections with I 2σ（I）.
基金supported by the University Science Foundation of Anhui Province (No. KJ2011Z271)the Applied Chemistry Key Constructing Subject of Anhui Province (No. 200802187C)
文摘Two complexes, [Cu2（Htdb）4（H2O）2] （1） and [Cd（bipy）2（Hmcmbc）2] （2） （H2tdb = 2,2-thiodibenzoic acid, H2mcmbc = m-（carboxyl-methyloxy）-benzenecarboxylic acid, bipy = 4,4＇-bipyridine）, have been prepared, and were characterized by elemental analysis, FT-IR and single-crystal X-ray diffraction. Structures indicate that complex 1 is a single molecule, and 2 is a one-dimensional chain. Their two-and three-dimensional frameworks are constructed through hydrogen bonding, π…π or C–H…π stacking, and such other weak interactions. The cyclic voltametric behavior of complex 1 and luminescence property of complex 2 were investigated. 1 belongs to the triclinic system, space group P with a = 7.8607（6）, b = 11.7619（9）, c = 15.3481（12） , α = 109.3670（10）, β = 92.4420（10）, γ = 92.0450（10）°, V = 1335.65（18） 3, Mr = 1256.26, Dc = 1.5619（2） g/cm3, F（000） = 642, μ = 1.029 mm–1, Z = 1, the final R = 0.0289 and wR = 0.0763 for 5199 observed reflections with I 2σ（I）. Complex 2 crystallizes in triclinic, space group P with a = 9.6378（10）, b = 9.7508（10）, c = 19.055（2） , α = 88.7020（10）, β = 80.5260（10）, γ = 69.2000（10）o, V = 1649.9（3） 3, Mr = 815.07, Dc = 1.641 g/cm3, μ = 0.732 mm-1, F（000） = 828, Z = 2, the final R = 0.0511 and wR = 0.1149 for 4729 observed reflections （I 2σ（I））.
