期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
上颌窦鳞癌中CyclinD1和CyclinE的表达及其意义 被引量:1
1
作者 王建波 王瑛 《中国肿瘤临床与康复》 2004年第4期300-302,共3页
目的检测上颌窦鳞癌、上颌窦内翻性乳头状瘤及上颌窦炎性黏膜中CyclinD1和CyclinE的表达情况,并分析其表达与上颌窦鳞癌临床病理特性之间的关系。方法应用免疫组化方法检测50例上颌窦鳞癌、20例上颌窦内翻性乳头状瘤、10例上颌窦炎性黏... 目的检测上颌窦鳞癌、上颌窦内翻性乳头状瘤及上颌窦炎性黏膜中CyclinD1和CyclinE的表达情况,并分析其表达与上颌窦鳞癌临床病理特性之间的关系。方法应用免疫组化方法检测50例上颌窦鳞癌、20例上颌窦内翻性乳头状瘤、10例上颌窦炎性黏膜中CyclinD1和CyclinE的表达情况。结果在上颌窦鳞癌、上颌窦内翻性乳头状瘤及上颌窦炎性黏膜中,CyclinD1阳性表达率分别为10.0%、25.0%和48.0%(P<0.05);CyclinE阳性表达率分别为20.0%、35.0%和58.0%(P<0.05)。CyclinD1和CyclinE阳性表达率与上颌窦鳞癌患者的性别、T分型无显著相关(P>0.05)。CyclinD1和CyclinE在高、中和低分化的喉癌中阳性表达率组间比较差异无显著性(P均>0.05)。结论在上颌窦炎性黏膜、上颌窦内翻性乳头状瘤及上颌窦鳞癌中,随病变加重,CyclinD1、CyclinE阳性表达率呈逐渐升高的趋势。细胞周期调控网络中,细胞周期调控因子的异常可能是上颌窦鳞癌发生发展的内在原因。 展开更多
关键词 上颌窦肿瘤 CycliD1基因 CyclinE基因
下载PDF
Cyclical Elliptical Pedal Surfaces
2
作者 Eva Baranova 《Journal of Mathematics and System Science》 2011年第1期1-6,共6页
Intensive use of geometrical modelling started with the development of computer graphics and CAD/CAM technologies, comprising a wide area of mathematical disciplines. Geometrical modelling is a synthesis of the geomet... Intensive use of geometrical modelling started with the development of computer graphics and CAD/CAM technologies, comprising a wide area of mathematical disciplines. Geometrical modelling is a synthesis of the geometry and computer graphics, which enable us to develop complex mathematical models that would be rather difficult to display without using a computer. The author recognizes two basic methods of research of geometrical models, synthetic and analytic. The synthetic method makes use of geometrical constructions and in the analytic method geometrical objects are characterized by numerical data. The author uses these methods in this contribution. The aim of this research is to show central cyclides (Dupin's cyclides) as a special kind of the cyclical elliptical pedal surfaces. Firstly, applying the method of synthetic geometry, a new class of such surfaces in the 3-dimensional Euclidean space (model of the projective space) is defined. The geometrical construction of these surfaces is dependent on the given ellipse and the position of the pole P. It is the point at which the pencil of perpendicular planes passes to the plane of the ellipse, wherein the generating circles of the surface are lying. The parametric equations of the cyclical elliptical surface are derived applying the method of analytic geometry. The author classifies the surfaces according to the number of generating circles with a zero radius. The evolute of the ellipse divides the plane of the ellipse into two areas, Ω1 and Ω2. The shape of the surface depends on the position of the pole P in the areas of Ω1 and Ω2. The surface can have 4, 3 or 2 circles with a zero radius. The author then describes the relationship between these surfaces and the Dupin's cyclides, obtained in the case when the pole P is the point on the major axis of the ellipse. Finally, the transformation of these surfaces is shown by changing of the orthonormal base in the parameterization of the generating circles of the surface. The author visualizes the resulting surfaces obtained by the parametric approach in the MAPLE program environment. 展开更多
关键词 Cyclical elliptical pedal surfaces CREATION CLASSIFICATION Dupin's cyclides.
下载PDF
卡泊三醇对银屑病患者角质形成细胞的细胞周期素 D1、周期蛋白依赖性激酶及其抑制物 P16表达的影响 被引量:3
3
作者 李银涛 李世荫 +1 位作者 桑建利 张波 《中华皮肤科杂志》 CSCD 北大核心 2000年第2期108-109,共2页
关键词 银屑病 角质形成细胞 CycliD1 CDK4 CKI
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部