Eight 1,2-disubstituted cyclododecenes were synthesized from -alkoxycarbonyl-cyclododecanone and alkyl chloroformate. Their configuration and conformation determined by IR, NMR spectroscopy and X-ray diffraction analy...Eight 1,2-disubstituted cyclododecenes were synthesized from -alkoxycarbonyl-cyclododecanone and alkyl chloroformate. Their configuration and conformation determined by IR, NMR spectroscopy and X-ray diffraction analysis showed that the carbon-carbon double bond of all of the synthesized compounds has cis-configuration, and the ring skeleton of their preferred conformation is [1ene2333] in solid, and they may adopt two different [1ene2333] conformations,which exist in a dynamic equilibrium in solution.展开更多
基金Project supported by the National Natural Science Foundation of China (No. 20072053).
文摘Eight 1,2-disubstituted cyclododecenes were synthesized from -alkoxycarbonyl-cyclododecanone and alkyl chloroformate. Their configuration and conformation determined by IR, NMR spectroscopy and X-ray diffraction analysis showed that the carbon-carbon double bond of all of the synthesized compounds has cis-configuration, and the ring skeleton of their preferred conformation is [1ene2333] in solid, and they may adopt two different [1ene2333] conformations,which exist in a dynamic equilibrium in solution.
