Experiments carried out using a lung model with a single horizontal bifurcation under different steady inhalation conditions explored the orientation of depositing carbon fibers, and particle deposition frac- tions. T...Experiments carried out using a lung model with a single horizontal bifurcation under different steady inhalation conditions explored the orientation of depositing carbon fibers, and particle deposition frac- tions. The orientations of deposited fibers were obtained from micrographs. Specifically, the effects of the sedimentation parameter （γ）, fiber length, and flow rate on orientations were analyzed. Our results indicate that gravitational effect on deposition cannot be neglected for 0.0228 〈 γ 〈 0.247. The absolute orientation angle of depositing fibers decreased linearly with increasing y for values 0.0228 〈 γ 〈 0.15. Correspondence between Stokes numbers and y suggests these characteristics can be used to estimate fiber deposition in the lower airways. Computer simulations with sphere-equivalent diameter models for the fibers explored deposition efficiency vs. Stokes number. Using the volume-equivalent diameter model, our experimental data for the horizontal bifurcation were replicated. Results for particle deposition using a lung model with a vertical bifurcation indicate that body position also affects deposition.展开更多
基金We acknowledge the financial support of the Foundation for the National Natural Science Foundation of China （No. 51176035）, and Author of National Excellent Doctoral Dissertation of China （No. 201040）. In addition, financial support was provided to Xiaole Chen under the Research and Innovation Project for College Gradua- tes of Jiangsu Province （CXZZ12_0099）, the Fundamental Research Funds for the Central Universities, China Scholarship Council （No. 201306090085）, and Scientific Research Foundation of Graduate School of Southeast University （No. YBJJ1209）. The experience gained by Xiaole Chen as a CSC-supported Visiting Student in the Computational Multi-Physics Lab （MAE Dept., NC State University, Raleigh, USA） is also acknowledged. Table 3, Figs. 5 and 7 were provided by Josin Tom, based on his spring 2015 course-project report for MAE558. Professor Goodarz Ahmadi at Clarkson Univer- sity （Clarkson, USA） provided advice for our experimental set-up, and Professor Yong Lu at Southeast University provided guidance in programming the image-processing method.
文摘Experiments carried out using a lung model with a single horizontal bifurcation under different steady inhalation conditions explored the orientation of depositing carbon fibers, and particle deposition frac- tions. The orientations of deposited fibers were obtained from micrographs. Specifically, the effects of the sedimentation parameter （γ）, fiber length, and flow rate on orientations were analyzed. Our results indicate that gravitational effect on deposition cannot be neglected for 0.0228 〈 γ 〈 0.247. The absolute orientation angle of depositing fibers decreased linearly with increasing y for values 0.0228 〈 γ 〈 0.15. Correspondence between Stokes numbers and y suggests these characteristics can be used to estimate fiber deposition in the lower airways. Computer simulations with sphere-equivalent diameter models for the fibers explored deposition efficiency vs. Stokes number. Using the volume-equivalent diameter model, our experimental data for the horizontal bifurcation were replicated. Results for particle deposition using a lung model with a vertical bifurcation indicate that body position also affects deposition.
