Brain tissue is one of the softest parts of the human body,composed of white matter and grey matter.The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function...Brain tissue is one of the softest parts of the human body,composed of white matter and grey matter.The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function.Besides,traumatic brain injury(TBI)and various brain diseases are also greatly influenced by the brain's mechanical properties.Whether white matter or grey matter,brain tissue contains multiscale structures composed of neurons,glial cells,fibers,blood vessels,etc.,each with different mechanical properties.As such,brain tissue exhibits complex mechanical behavior,usually with strong nonlinearity,heterogeneity,and directional dependence.Building a constitutive law for multiscale brain tissue using traditional function-based approaches can be very challenging.Instead,this paper proposes a data-driven approach to establish the desired mechanical model of brain tissue.We focus on blood vessels with internal pressure embedded in a white or grey matter matrix material to demonstrate our approach.The matrix is described by an isotropic or anisotropic nonlinear elastic model.A representative unit cell(RUC)with blood vessels is built,which is used to generate the stress-strain data under different internal blood pressure and various proportional displacement loading paths.The generated stress-strain data is then used to train a mechanical law using artificial neural networks to predict the macroscopic mechanical response of brain tissue under different internal pressures.Finally,the trained material model is implemented into finite element software to predict the mechanical behavior of a whole brain under intracranial pressure and distributed body forces.Compared with a direct numerical simulation that employs a reference material model,our proposed approach greatly reduces the computational cost and improves modeling efficiency.The predictions made by our trained model demonstrate sufficient accuracy.Specifically,we find that the level of internal blood pressure can greatly influence stress distribution and determine the possible related damage behaviors.展开更多
With the ongoing advancements in sensor networks and data acquisition technologies across various systems like manufacturing,aviation,and healthcare,the data driven vibration control(DDVC)has attracted broad interests...With the ongoing advancements in sensor networks and data acquisition technologies across various systems like manufacturing,aviation,and healthcare,the data driven vibration control(DDVC)has attracted broad interests from both the industrial and academic communities.Input shaping(IS),as a simple and effective feedforward method,is greatly demanded in DDVC methods.It convolves the desired input command with impulse sequence without requiring parametric dynamics and the closed-loop system structure,thereby suppressing the residual vibration separately.Based on a thorough investigation into the state-of-the-art DDVC methods,this survey has made the following efforts:1)Introducing the IS theory and typical input shapers;2)Categorizing recent progress of DDVC methods;3)Summarizing commonly adopted metrics for DDVC;and 4)Discussing the engineering applications and future trends of DDVC.By doing so,this study provides a systematic and comprehensive overview of existing DDVC methods from designing to optimizing perspectives,aiming at promoting future research regarding this emerging and vital issue.展开更多
The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fu...The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fulfill dynamic demands of information sharing between government agencies.Motivated by blockchain and data mining,a data-driven framework is proposed for IAGIS in this paper.Firstly,the blockchain is used as the core to design the whole framework for monitoring and preventing leakage and abuse of government information,in order to guarantee information security.Secondly,a four-layer architecture is designed for implementing the proposed framework.Thirdly,the classical data mining algorithms PageRank and Apriori are applied to dynamically design smart contracts for information sharing,for the purposed of flexibly adjusting the information sharing strategies according to the practical demands of government agencies for public management and public service.Finally,a case study is presented to illustrate the operation of the proposed framework.展开更多
Although big data is publicly available on water quality parameters,virtual simulation has not yet been adequately adapted in environmental chemistry research.Digital twin is different from conventional geospatial mod...Although big data is publicly available on water quality parameters,virtual simulation has not yet been adequately adapted in environmental chemistry research.Digital twin is different from conventional geospatial modeling approaches and is particularly useful when systematic laboratory/field experiment is not realistic(e.g.,climate impact and water-related environmental catastrophe)or difficult to design and monitor in a real time(e.g.,pollutant and nutrient cycles in estuaries,soils,and sediments).Data-driven water research could realize early warning and disaster readiness simulations for diverse environmental scenarios,including drinking water contamination.展开更多
Magnesium(Mg)is a promising alternative to lithium(Li)as an anode material in solid-state batteries due to its abundance and high theoretical volumetric capacity.However,the sluggish Mg-ion conduction in the lattice o...Magnesium(Mg)is a promising alternative to lithium(Li)as an anode material in solid-state batteries due to its abundance and high theoretical volumetric capacity.However,the sluggish Mg-ion conduction in the lattice of solidstate electrolytes(SSEs)is one of the key challenges that hamper the development of Mg-ion solid-state batteries.Though various Mg-ion SSEs have been reported in recent years,key insights are hard to be derived from a single literature report.Besides,the structure-performance relationships of Mg-ion SSEs need to be further unraveled to provide a more precise design guideline for SSEs.In this viewpoint article,we analyze the structural characteristics of the Mg-based SSEs with high ionic conductivity reported in the last four decades based upon data mining-we provide big-data-derived insights into the challenges and opportunities in developing next-generation Mg-ion SSEs.展开更多
Long-term navigation ability based on consumer-level wearable inertial sensors plays an essential role towards various emerging fields, for instance, smart healthcare, emergency rescue, soldier positioning et al. The ...Long-term navigation ability based on consumer-level wearable inertial sensors plays an essential role towards various emerging fields, for instance, smart healthcare, emergency rescue, soldier positioning et al. The performance of existing long-term navigation algorithm is limited by the cumulative error of inertial sensors, disturbed local magnetic field, and complex motion modes of the pedestrian. This paper develops a robust data and physical model dual-driven based trajectory estimation(DPDD-TE) framework, which can be applied for long-term navigation tasks. A Bi-directional Long Short-Term Memory(Bi-LSTM) based quasi-static magnetic field(QSMF) detection algorithm is developed for extracting useful magnetic observation for heading calibration, and another Bi-LSTM is adopted for walking speed estimation by considering hybrid human motion information under a specific time period. In addition, a data and physical model dual-driven based multi-source fusion model is proposed to integrate basic INS mechanization and multi-level constraint and observations for maintaining accuracy under long-term navigation tasks, and enhanced by the magnetic and trajectory features assisted loop detection algorithm. Real-world experiments indicate that the proposed DPDD-TE outperforms than existing algorithms, and final estimated heading and positioning accuracy indexes reaches 5° and less than 2 m under the time period of 30 min, respectively.展开更多
Peanut allergy is majorly related to severe food induced allergic reactions.Several food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fis...Peanut allergy is majorly related to severe food induced allergic reactions.Several food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fish and shellfish are responsible for more than 90%of food allergies.Here,we provide promising insights using a large-scale data-driven analysis,comparing the mechanistic feature and biological relevance of different ingredients presents in peanuts,tree nuts(walnuts,almonds,cashews,pecans and pistachios)and soybean.Additionally,we have analysed the chemical compositions of peanuts in different processed form raw,boiled and dry-roasted.Using the data-driven approach we are able to generate new hypotheses to explain why nuclear receptors like the peroxisome proliferator-activated receptors(PPARs)and its isoform and their interaction with dietary lipids may have significant effect on allergic response.The results obtained from this study will direct future experimeantal and clinical studies to understand the role of dietary lipids and PPARisoforms to exert pro-inflammatory or anti-inflammatory functions on cells of the innate immunity and influence antigen presentation to the cells of the adaptive immunity.展开更多
With the increased availability of experimental measurements aiming at probing wind resources and wind turbine operations,machine learning(ML)models are poised to advance our understanding of the physics underpinning ...With the increased availability of experimental measurements aiming at probing wind resources and wind turbine operations,machine learning(ML)models are poised to advance our understanding of the physics underpinning the interaction between the atmospheric boundary layer and wind turbine arrays,the generated wakes and their interactions,and wind energy harvesting.However,the majority of the existing ML models for predicting wind turbine wakes merely recreate Computational fluid dynamics(CFD)simulated data with analogous accuracy but reduced computational costs,thus providing surrogate models rather than enhanced data-enabled physics insights.Although ML-based surrogate models are useful to overcome current limitations associated with the high computational costs of CFD models,using ML to unveil processes from experimental data or enhance modeling capabilities is deemed a potential research direction to pursue.In this letter,we discuss recent achievements in the realm of ML modeling of wind turbine wakes and operations,along with new promising research strategies.展开更多
Cable-stayed bridges have been widely used in high-speed railway infrastructure.The accurate determination of cable’s representative temperatures is vital during the intricate processes of design,construction,and mai...Cable-stayed bridges have been widely used in high-speed railway infrastructure.The accurate determination of cable’s representative temperatures is vital during the intricate processes of design,construction,and maintenance of cable-stayed bridges.However,the representative temperatures of stayed cables are not specified in the existing design codes.To address this issue,this study investigates the distribution of the cable temperature and determinates its representative temperature.First,an experimental investigation,spanning over a period of one year,was carried out near the bridge site to obtain the temperature data.According to the statistical analysis of the measured data,it reveals that the temperature distribution is generally uniform along the cable cross-section without significant temperature gradient.Then,based on the limited data,the Monte Carlo,the gradient boosted regression trees(GBRT),and univariate linear regression(ULR)methods are employed to predict the cable’s representative temperature throughout the service life.These methods effectively overcome the limitations of insufficient monitoring data and accurately predict the representative temperature of the cables.However,each method has its own advantages and limitations in terms of applicability and accuracy.A comprehensive evaluation of the performance of these methods is conducted,and practical recommendations are provided for their application.The proposed methods and representative temperatures provide a good basis for the operation and maintenance of in-service long-span cable-stayed bridges.展开更多
Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subse...Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are missing.We recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within clusters.Here we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical testing.These general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical datasets.We demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.展开更多
There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful...There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful aids in their clinical decision-making while also preserving patient privacy.This is especially important given the epidemiology of chronic kidney disease,renal oncology,and hypertension worldwide.However,there remains a need to create a framework for guidance regarding how to better utilize synthetic data as a practical application in this research.展开更多
Dynamic data driven simulation (DDDS) is proposed to improve the model by incorporaing real data from the practical systems into the model. Instead of giving a static input, multiple possible sets of inputs are fed ...Dynamic data driven simulation (DDDS) is proposed to improve the model by incorporaing real data from the practical systems into the model. Instead of giving a static input, multiple possible sets of inputs are fed into the model. And the computational errors are corrected using statistical approaches. It involves a variety of aspects, including the uncertainty modeling, the measurement evaluation, the system model and the measurement model coupling ,the computation complexity, and the performance issue. Authors intend to set up the architecture of DDDS for wildfire spread model, DEVS-FIRE, based on the discrete event speeification (DEVS) formalism. The experimental results show that the framework can track the dynamically changing fire front based on fire sen- sor data, thus, it provides more aecurate predictions.展开更多
Hydrocarbon production from shale has attracted much attention in the recent years. When applied to this prolific and hydrocarbon rich resource plays, our understanding of the complexities of the flow mechanism(sorpt...Hydrocarbon production from shale has attracted much attention in the recent years. When applied to this prolific and hydrocarbon rich resource plays, our understanding of the complexities of the flow mechanism(sorption process and flow behavior in complex fracture systems- induced or natural) leaves much to be desired. In this paper, we present and discuss a novel approach to modeling, history matching of hydrocarbon production from a Marcellus shale asset in southwestern Pennsylvania using advanced data mining, pattern recognition and machine learning technologies. In this new approach instead of imposing our understanding of the flow mechanism, the impact of multi-stage hydraulic fractures, and the production process on the reservoir model, we allow the production history, well log, completion and hydraulic fracturing data to guide our model and determine its behavior. The uniqueness of this technology is that it incorporates the so-called "hard data" directly into the reservoir model, so that the model can be used to optimize the hydraulic fracture process. The "hard data" refers to field measurements during the hydraulic fracturing process such as fluid and proppant type and amount, injection pressure and rate as well as proppant concentration. This novel approach contrasts with the current industry focus on the use of "soft data"(non-measured, interpretive data such as frac length, width,height and conductivity) in the reservoir models. The study focuses on a Marcellus shale asset that includes 135 wells with multiple pads, different landing targets, well length and reservoir properties. The full field history matching process was successfully completed using this data driven approach thus capturing the production behavior with acceptable accuracy for individual wells and for the entire asset.展开更多
During the past few decades,mobile wireless communications have experienced four generations of technological revolution,namely from 1 G to 4 G,and the deployment of the latest 5 G networks is expected to take place i...During the past few decades,mobile wireless communications have experienced four generations of technological revolution,namely from 1 G to 4 G,and the deployment of the latest 5 G networks is expected to take place in 2019.One fundamental question is how we can push forward the development of mobile wireless communications while it has become an extremely complex and sophisticated system.We believe that the answer lies in the huge volumes of data produced by the network itself,and machine learning may become a key to exploit such information.In this paper,we elaborate why the conventional model-based paradigm,which has been widely proved useful in pre-5 G networks,can be less efficient or even less practical in the future 5 G and beyond mobile networks.Then,we explain how the data-driven paradigm,using state-of-the-art machine learning techniques,can become a promising solution.At last,we provide a typical use case of the data-driven paradigm,i.e.,proactive load balancing,in which online learning is utilized to adjust cell configurations in advance to avoid burst congestion caused by rapid traffic changes.展开更多
Fault prognosis is mainly referred to the estimation of the operating time before a failure occurs,which is vital for ensuring the stability,safety and long lifetime of degrading industrial systems.According to the re...Fault prognosis is mainly referred to the estimation of the operating time before a failure occurs,which is vital for ensuring the stability,safety and long lifetime of degrading industrial systems.According to the results of fault prognosis,the maintenance strategy for underlying industrial systems can realize the conversion from passive maintenance to active maintenance.With the increased complexity and the improved automation level of industrial systems,fault prognosis techniques have become more and more indispensable.Particularly,the datadriven based prognosis approaches,which tend to find the hidden fault factors and determine the specific fault occurrence time of the system by analysing historical or real-time measurement data,gain great attention from different industrial sectors.In this context,the major task of this paper is to present a systematic overview of data-driven fault prognosis for industrial systems.Firstly,the characteristics of different prognosis methods are revealed with the data-based ones being highlighted.Moreover,based on the different data characteristics that exist in industrial systems,the corresponding fault prognosis methodologies are illustrated,with emphasis on analyses and comparisons of different prognosis methods.Finally,we reveal the current research trends and look forward to the future challenges in this field.This review is expected to serve as a tutorial and source of references for fault prognosis researchers.展开更多
To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions...To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions of the machine and tooling during machining processes,the relevant diagnosis systems currently adopted in industries are incompetent.To address this issue,this paper presents a novel data-driven diagnosis system for anomalies.In this system,power data for condition monitoring are continuously collected during dynamic machining processes to support online diagnosis analysis.To facilitate the analysis,preprocessing mechanisms have been designed to de-noise,normalize,and align the monitored data.Important features are extracted from the monitored data and thresholds are defined to identify anomalies.Considering the dynamic conditions of the machine and tooling during machining processes,the thresholds used to identify anomalies can vary.Based on historical data,the values of thresholds are optimized using a fruit fly optimization(FFO)algorithm to achieve more accurate detection.Practical case studies were used to validate the system,thereby demonstrating the potential and effectiveness of the system for industrial applications.展开更多
This paper presents a simple nonparametric regression approach to data-driven computing in elasticity. We apply the kernel regression to the material data set, and formulate a system of nonlinear equations solved to o...This paper presents a simple nonparametric regression approach to data-driven computing in elasticity. We apply the kernel regression to the material data set, and formulate a system of nonlinear equations solved to obtain a static equilibrium state of an elastic structure. Preliminary numerical experiments illustrate that, compared with existing methods, the proposed method finds a reasonable solution even if data points distribute coarsely in a given material data set.展开更多
文摘Brain tissue is one of the softest parts of the human body,composed of white matter and grey matter.The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function.Besides,traumatic brain injury(TBI)and various brain diseases are also greatly influenced by the brain's mechanical properties.Whether white matter or grey matter,brain tissue contains multiscale structures composed of neurons,glial cells,fibers,blood vessels,etc.,each with different mechanical properties.As such,brain tissue exhibits complex mechanical behavior,usually with strong nonlinearity,heterogeneity,and directional dependence.Building a constitutive law for multiscale brain tissue using traditional function-based approaches can be very challenging.Instead,this paper proposes a data-driven approach to establish the desired mechanical model of brain tissue.We focus on blood vessels with internal pressure embedded in a white or grey matter matrix material to demonstrate our approach.The matrix is described by an isotropic or anisotropic nonlinear elastic model.A representative unit cell(RUC)with blood vessels is built,which is used to generate the stress-strain data under different internal blood pressure and various proportional displacement loading paths.The generated stress-strain data is then used to train a mechanical law using artificial neural networks to predict the macroscopic mechanical response of brain tissue under different internal pressures.Finally,the trained material model is implemented into finite element software to predict the mechanical behavior of a whole brain under intracranial pressure and distributed body forces.Compared with a direct numerical simulation that employs a reference material model,our proposed approach greatly reduces the computational cost and improves modeling efficiency.The predictions made by our trained model demonstrate sufficient accuracy.Specifically,we find that the level of internal blood pressure can greatly influence stress distribution and determine the possible related damage behaviors.
基金supported by the National Natural Science Foundation of China (62272078)。
文摘With the ongoing advancements in sensor networks and data acquisition technologies across various systems like manufacturing,aviation,and healthcare,the data driven vibration control(DDVC)has attracted broad interests from both the industrial and academic communities.Input shaping(IS),as a simple and effective feedforward method,is greatly demanded in DDVC methods.It convolves the desired input command with impulse sequence without requiring parametric dynamics and the closed-loop system structure,thereby suppressing the residual vibration separately.Based on a thorough investigation into the state-of-the-art DDVC methods,this survey has made the following efforts:1)Introducing the IS theory and typical input shapers;2)Categorizing recent progress of DDVC methods;3)Summarizing commonly adopted metrics for DDVC;and 4)Discussing the engineering applications and future trends of DDVC.By doing so,this study provides a systematic and comprehensive overview of existing DDVC methods from designing to optimizing perspectives,aiming at promoting future research regarding this emerging and vital issue.
基金Supported by the Project of Guangdong Science and Technology Department(2020B010166005)the Post-Doctoral Research Project(Z000158)+2 种基金the Ministry of Education Social Science Fund(22YJ630167)the Fund project of Department of Science and Technology of Guangdong Province(GDK TP2021032500)the Guangdong Philosophy and Social Science(GD22YYJ15).
文摘The inter-agency government information sharing(IAGIS)plays an important role in improving service and efficiency of government agencies.Currently,there is still no effective and secure way for data-driven IAGIS to fulfill dynamic demands of information sharing between government agencies.Motivated by blockchain and data mining,a data-driven framework is proposed for IAGIS in this paper.Firstly,the blockchain is used as the core to design the whole framework for monitoring and preventing leakage and abuse of government information,in order to guarantee information security.Secondly,a four-layer architecture is designed for implementing the proposed framework.Thirdly,the classical data mining algorithms PageRank and Apriori are applied to dynamically design smart contracts for information sharing,for the purposed of flexibly adjusting the information sharing strategies according to the practical demands of government agencies for public management and public service.Finally,a case study is presented to illustrate the operation of the proposed framework.
文摘Although big data is publicly available on water quality parameters,virtual simulation has not yet been adequately adapted in environmental chemistry research.Digital twin is different from conventional geospatial modeling approaches and is particularly useful when systematic laboratory/field experiment is not realistic(e.g.,climate impact and water-related environmental catastrophe)or difficult to design and monitor in a real time(e.g.,pollutant and nutrient cycles in estuaries,soils,and sediments).Data-driven water research could realize early warning and disaster readiness simulations for diverse environmental scenarios,including drinking water contamination.
基金supported by the Ensemble Grant for Early Career Researchers 2022-2023 and the 2023 Ensemble Continuation Grant of Tohoku University,the Hirose Foundation,and the AIMR Fusion Research Grantsupported by JSPS KAKENHI Nos.JP23K13599,JP23K13703,JP22H01803,JP18H05513,and JP23K13542.F.Y.and Q.W.acknowledge the China Scholarship Council(CSC)to support their studies in Japan.
文摘Magnesium(Mg)is a promising alternative to lithium(Li)as an anode material in solid-state batteries due to its abundance and high theoretical volumetric capacity.However,the sluggish Mg-ion conduction in the lattice of solidstate electrolytes(SSEs)is one of the key challenges that hamper the development of Mg-ion solid-state batteries.Though various Mg-ion SSEs have been reported in recent years,key insights are hard to be derived from a single literature report.Besides,the structure-performance relationships of Mg-ion SSEs need to be further unraveled to provide a more precise design guideline for SSEs.In this viewpoint article,we analyze the structural characteristics of the Mg-based SSEs with high ionic conductivity reported in the last four decades based upon data mining-we provide big-data-derived insights into the challenges and opportunities in developing next-generation Mg-ion SSEs.
文摘Long-term navigation ability based on consumer-level wearable inertial sensors plays an essential role towards various emerging fields, for instance, smart healthcare, emergency rescue, soldier positioning et al. The performance of existing long-term navigation algorithm is limited by the cumulative error of inertial sensors, disturbed local magnetic field, and complex motion modes of the pedestrian. This paper develops a robust data and physical model dual-driven based trajectory estimation(DPDD-TE) framework, which can be applied for long-term navigation tasks. A Bi-directional Long Short-Term Memory(Bi-LSTM) based quasi-static magnetic field(QSMF) detection algorithm is developed for extracting useful magnetic observation for heading calibration, and another Bi-LSTM is adopted for walking speed estimation by considering hybrid human motion information under a specific time period. In addition, a data and physical model dual-driven based multi-source fusion model is proposed to integrate basic INS mechanization and multi-level constraint and observations for maintaining accuracy under long-term navigation tasks, and enhanced by the magnetic and trajectory features assisted loop detection algorithm. Real-world experiments indicate that the proposed DPDD-TE outperforms than existing algorithms, and final estimated heading and positioning accuracy indexes reaches 5° and less than 2 m under the time period of 30 min, respectively.
文摘Peanut allergy is majorly related to severe food induced allergic reactions.Several food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fish and shellfish are responsible for more than 90%of food allergies.Here,we provide promising insights using a large-scale data-driven analysis,comparing the mechanistic feature and biological relevance of different ingredients presents in peanuts,tree nuts(walnuts,almonds,cashews,pecans and pistachios)and soybean.Additionally,we have analysed the chemical compositions of peanuts in different processed form raw,boiled and dry-roasted.Using the data-driven approach we are able to generate new hypotheses to explain why nuclear receptors like the peroxisome proliferator-activated receptors(PPARs)and its isoform and their interaction with dietary lipids may have significant effect on allergic response.The results obtained from this study will direct future experimeantal and clinical studies to understand the role of dietary lipids and PPARisoforms to exert pro-inflammatory or anti-inflammatory functions on cells of the innate immunity and influence antigen presentation to the cells of the adaptive immunity.
基金supported by the National Science Foundation(NSF)CBET,Fluid Dynamics CAREER program(Grant No.2046160),program manager Ron Joslin.
文摘With the increased availability of experimental measurements aiming at probing wind resources and wind turbine operations,machine learning(ML)models are poised to advance our understanding of the physics underpinning the interaction between the atmospheric boundary layer and wind turbine arrays,the generated wakes and their interactions,and wind energy harvesting.However,the majority of the existing ML models for predicting wind turbine wakes merely recreate Computational fluid dynamics(CFD)simulated data with analogous accuracy but reduced computational costs,thus providing surrogate models rather than enhanced data-enabled physics insights.Although ML-based surrogate models are useful to overcome current limitations associated with the high computational costs of CFD models,using ML to unveil processes from experimental data or enhance modeling capabilities is deemed a potential research direction to pursue.In this letter,we discuss recent achievements in the realm of ML modeling of wind turbine wakes and operations,along with new promising research strategies.
基金Project(2017G006-N)supported by the Project of Science and Technology Research and Development Program of China Railway Corporation。
文摘Cable-stayed bridges have been widely used in high-speed railway infrastructure.The accurate determination of cable’s representative temperatures is vital during the intricate processes of design,construction,and maintenance of cable-stayed bridges.However,the representative temperatures of stayed cables are not specified in the existing design codes.To address this issue,this study investigates the distribution of the cable temperature and determinates its representative temperature.First,an experimental investigation,spanning over a period of one year,was carried out near the bridge site to obtain the temperature data.According to the statistical analysis of the measured data,it reveals that the temperature distribution is generally uniform along the cable cross-section without significant temperature gradient.Then,based on the limited data,the Monte Carlo,the gradient boosted regression trees(GBRT),and univariate linear regression(ULR)methods are employed to predict the cable’s representative temperature throughout the service life.These methods effectively overcome the limitations of insufficient monitoring data and accurately predict the representative temperature of the cables.However,each method has its own advantages and limitations in terms of applicability and accuracy.A comprehensive evaluation of the performance of these methods is conducted,and practical recommendations are provided for their application.The proposed methods and representative temperatures provide a good basis for the operation and maintenance of in-service long-span cable-stayed bridges.
基金supported in part by NIH grants R01NS39600,U01MH114829RF1MH128693(to GAA)。
文摘Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are missing.We recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within clusters.Here we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical testing.These general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical datasets.We demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.
文摘There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful aids in their clinical decision-making while also preserving patient privacy.This is especially important given the epidemiology of chronic kidney disease,renal oncology,and hypertension worldwide.However,there remains a need to create a framework for guidance regarding how to better utilize synthetic data as a practical application in this research.
文摘Dynamic data driven simulation (DDDS) is proposed to improve the model by incorporaing real data from the practical systems into the model. Instead of giving a static input, multiple possible sets of inputs are fed into the model. And the computational errors are corrected using statistical approaches. It involves a variety of aspects, including the uncertainty modeling, the measurement evaluation, the system model and the measurement model coupling ,the computation complexity, and the performance issue. Authors intend to set up the architecture of DDDS for wildfire spread model, DEVS-FIRE, based on the discrete event speeification (DEVS) formalism. The experimental results show that the framework can track the dynamically changing fire front based on fire sen- sor data, thus, it provides more aecurate predictions.
基金Supported by National Basic Research Program of China (973 Program) (2009CB320600), National Natural Science Foundation of China (60828007, 60534010, 60821063), the Leverhulme Trust (F/00. 120/BC) in the United Kingdom, and the 111 Project (B08015)
基金Supported by State Key Program of National Natural Science Foundation of China (60834001) and National Natural Science Foundation of China (60774022).Acknowledgement Authors would like to thank NSFC organizers and participants who shared their ideas and works with us during the NSFC workshop on data-based control, decision making, scheduling, and fault diagnosis. In particular, authors would like to thank Chai Tian-You, Sun You-Xian, Wang Hong, Yan Hong-Sheng, and Gao Fu-Rong for discussing the concept on design model shown in Fig. 12, the concept on temporal multi-scale shown in Fig. 8, the concept on fault diagnosis shown in Fig. 14, the concept on dynamic scheduling shown in Fig. 15, and the concept on interval model shown in Fig. 16, respectively.
基金RPSEA and U.S.Department of Energy for partially funding this study
文摘Hydrocarbon production from shale has attracted much attention in the recent years. When applied to this prolific and hydrocarbon rich resource plays, our understanding of the complexities of the flow mechanism(sorption process and flow behavior in complex fracture systems- induced or natural) leaves much to be desired. In this paper, we present and discuss a novel approach to modeling, history matching of hydrocarbon production from a Marcellus shale asset in southwestern Pennsylvania using advanced data mining, pattern recognition and machine learning technologies. In this new approach instead of imposing our understanding of the flow mechanism, the impact of multi-stage hydraulic fractures, and the production process on the reservoir model, we allow the production history, well log, completion and hydraulic fracturing data to guide our model and determine its behavior. The uniqueness of this technology is that it incorporates the so-called "hard data" directly into the reservoir model, so that the model can be used to optimize the hydraulic fracture process. The "hard data" refers to field measurements during the hydraulic fracturing process such as fluid and proppant type and amount, injection pressure and rate as well as proppant concentration. This novel approach contrasts with the current industry focus on the use of "soft data"(non-measured, interpretive data such as frac length, width,height and conductivity) in the reservoir models. The study focuses on a Marcellus shale asset that includes 135 wells with multiple pads, different landing targets, well length and reservoir properties. The full field history matching process was successfully completed using this data driven approach thus capturing the production behavior with acceptable accuracy for individual wells and for the entire asset.
基金partially supported by the National Natural Science Foundation of China(61751306,61801208,61671233)the Jiangsu Science Foundation(BK20170650)+2 种基金the Postdoctoral Science Foundation of China(BX201700118,2017M621712)the Jiangsu Postdoctoral Science Foundation(1701118B)the Fundamental Research Funds for the Central Universities(021014380094)
文摘During the past few decades,mobile wireless communications have experienced four generations of technological revolution,namely from 1 G to 4 G,and the deployment of the latest 5 G networks is expected to take place in 2019.One fundamental question is how we can push forward the development of mobile wireless communications while it has become an extremely complex and sophisticated system.We believe that the answer lies in the huge volumes of data produced by the network itself,and machine learning may become a key to exploit such information.In this paper,we elaborate why the conventional model-based paradigm,which has been widely proved useful in pre-5 G networks,can be less efficient or even less practical in the future 5 G and beyond mobile networks.Then,we explain how the data-driven paradigm,using state-of-the-art machine learning techniques,can become a promising solution.At last,we provide a typical use case of the data-driven paradigm,i.e.,proactive load balancing,in which online learning is utilized to adjust cell configurations in advance to avoid burst congestion caused by rapid traffic changes.
基金supported by the National Natural Science Foundation of China(61773087)the National Key Research and Development Program of China(2018YFB1601500)High-tech Ship Research Project of Ministry of Industry and Information Technology-Research of Intelligent Ship Testing and Verifacation([2018]473)
文摘Fault prognosis is mainly referred to the estimation of the operating time before a failure occurs,which is vital for ensuring the stability,safety and long lifetime of degrading industrial systems.According to the results of fault prognosis,the maintenance strategy for underlying industrial systems can realize the conversion from passive maintenance to active maintenance.With the increased complexity and the improved automation level of industrial systems,fault prognosis techniques have become more and more indispensable.Particularly,the datadriven based prognosis approaches,which tend to find the hidden fault factors and determine the specific fault occurrence time of the system by analysing historical or real-time measurement data,gain great attention from different industrial sectors.In this context,the major task of this paper is to present a systematic overview of data-driven fault prognosis for industrial systems.Firstly,the characteristics of different prognosis methods are revealed with the data-based ones being highlighted.Moreover,based on the different data characteristics that exist in industrial systems,the corresponding fault prognosis methodologies are illustrated,with emphasis on analyses and comparisons of different prognosis methods.Finally,we reveal the current research trends and look forward to the future challenges in this field.This review is expected to serve as a tutorial and source of references for fault prognosis researchers.
基金funding from the EU Smarter project(PEOPLE-2013-IAPP-610675)
文摘To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions of the machine and tooling during machining processes,the relevant diagnosis systems currently adopted in industries are incompetent.To address this issue,this paper presents a novel data-driven diagnosis system for anomalies.In this system,power data for condition monitoring are continuously collected during dynamic machining processes to support online diagnosis analysis.To facilitate the analysis,preprocessing mechanisms have been designed to de-noise,normalize,and align the monitored data.Important features are extracted from the monitored data and thresholds are defined to identify anomalies.Considering the dynamic conditions of the machine and tooling during machining processes,the thresholds used to identify anomalies can vary.Based on historical data,the values of thresholds are optimized using a fruit fly optimization(FFO)algorithm to achieve more accurate detection.Practical case studies were used to validate the system,thereby demonstrating the potential and effectiveness of the system for industrial applications.
基金Supported by National Basic Research Program of China(973 Program)(2013CB035500) National Natural Science Foundation of China(61233004,61221003,61074061)+1 种基金 International Cooperation Program of Shanghai Science and Technology Commission (12230709600) the Higher Education Research Fund for the Doctoral Program of China(20120073130006)
基金supported by JSPS KAKENHI (Grants 17K06633 and 18K18898)
文摘This paper presents a simple nonparametric regression approach to data-driven computing in elasticity. We apply the kernel regression to the material data set, and formulate a system of nonlinear equations solved to obtain a static equilibrium state of an elastic structure. Preliminary numerical experiments illustrate that, compared with existing methods, the proposed method finds a reasonable solution even if data points distribute coarsely in a given material data set.