Clinical significance of large decompressive craniectomy to control intractable increased intracranial pressure in patients with traumatic brain injury

Objective To investigate the role of decompressive craniectomy (DC) to decrease intractable intracranial hypertension(ICH) due to diffuse brain swelling and / or cerebral edema after severe traumatic brain injury and the time window of DC to affect on prognosis. Methods The clinical record of 132 patients who underwent DC for posttraumatic intractable ICH in our hospital from July 2003 to

Effect of increased intra-abdominal pressure and decompressive laparotomy on aerated lung volume distribution

Increased intra-abdominal pressure(IAP) is common in intensive care patients,affecting aerated lung volume distribution.The current study deals with the effect of increased IAP and decompressive laparotomy on aerated lung volume distribution.The serial whole-lung computed tomography scans of 16 patients with increased IAP were retrospectively analyzed between July 2006 and July 2008 and compared to controls.The IAP increased from(12.1±2.3) mmHg on admission to(25.2±3.6) mmHg(P<0.01) before decompressive laparotomy and decreased to(14.7±2.8) mmHg after decompressive laparotomy.Mean time from admission to decompressive laparotomy and length of intensive-care unit(ICU) stay were 26 h and 16.2 d,respectively.The percentage of normally aerated lung volume on admission was significantly lower than that of controls(P<0.01).Prior to decompressive laparotomy,the total lung volume and percentage of normally aerated lung were significantly less in patients compared to controls(P<0.01),and the absolute volume of non-aerated lung and percentage of non-aerated lung were significantly higher in patients(P<0.01).Peak inspiratory pressure,partial pressure of carbon dioxide in arterial blood,and central venous pressure were higher in patients,while the ratio of partial pressure of arterial O2 to the fraction of inspired O2(PaO2/FIO2) was decreased relative to controls prior to laparotomy.An approximately 1.8 cm greater cranial displacement of the diaphragm in patients versus controls was observed before laparotomy.The sagittal diameter of the lung at the T6 level was significantly increased compared to controls on admission(P<0.01).After laparotomy,the volume and percentage of non-aerated lung decreased significantly while the percentage of normally aerated lung volume increased significantly(P<0.01).In conclusion,increased IAP decreases total lung volume while increasing non-aerated lung volume.Decompressive laparotomy is associated with resolution of these effects on lung volumes.