Clinical Value of Predictive Nursing Intervention on Deep Venous Thrombosis of Lower Extremities after Cesarean Section

[Objectives]To explore the clinical nursing value of predictive nursing intervention in patients with deep venous thrombosis of lower extremities after cesarean section.[Methods]From December 2022 to April 2023,105 pregnant and lying-in women who were hospitalized in the Gynecology Department of Pingquan Hospital and underwent cesarean section and met the inclusion criteria were included as the study objects.According to the medical records,they were divided into observation group(n=52 cases)and control group(n=53 cases).The clinical experimental subjects were divided into two groups.One group was the control group with routine nursing,and the other group was the observation group with predictive nursing intervention.The number of cases of deep venous thrombosis of lower extremities in the two groups was recorded to evaluate the clinical value.[Results]The incidence of deep venous thrombosis of lower extremities in the two groups after cesarean section was compared,and it was suggested that the incidence of the observation group was lower than that of the control group(P<0.05).[Conclusions]Special predictive nursing intervention can greatly reduce the incidence of deep venous thrombosis of lower extremities after cesarean section,improve nursing satisfaction,and improve clinical efficacy,which is worthy of recommendation.

Predictive Value of Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation, and Systemic Inflammation Response Index in Lower Extremity Deep Venous Thrombosis Following Severe Trauma

Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lower extremity deep venous thrombosis(LEDVT)in a severely traumatized population and to evaluate their predictive value for LEDVT.Methods This was a retrospective,single-center observational study.All subjects were severely traumatized patients who were admitted to the Traumatic Intensive Care Unit from January 2021 to May 2024.Based on Doppler ultrasound findings of both lower extremities from the time of injury to 30 days post-injury,patients who developed LEDVT were enrolled in the LEDVT group,and those who did not develop LEDVT were enrolled in the NLEDVT group.Demographic,clinical,and laboratory data were collected upon admission.Multivariable logistic regression analysis was performed to identify risk factors for LEDVT.Receiver operating characteristic(ROC)curve was used to evaluate the overall fit of the final model.Results There were 56 patients enrolled in the LEDVT group and 81 patients in the NLEDVT group.Age,Aggregate Index of Systemic Inflammation(AISI),Systemic Inflammation Response Index(SIRI),ICU length of stay,and albumin were identified as independent risk factors for LEDVT(all P<0.05).The area under their ROC curves were 0.604,0.657,0.694,0.668,and 0.405,respectively.Combined model for early clinical prediction of LEDVT in severely traumatized patients by age,SIRI,AISI,and albumin resulted in an area under the ROC curve of 0.805(95%CI:0.73-0.88,SE=0.037).Conclusion The combination of age,SIRI,AISI,and albumin has a predictive value for LEDVT in severely traumatized patients.

Efficacy of percutaneous mechanical thrombus removal in acute lower extremity deep venous thrombosis

BACKGROUND Acute lower extremity deep venous thrombosis(LEDVT)is a common vascular emergency with significant morbidity risks,including post-thrombotic syndrome(PTS)and pulmonary embolism.Traditional treatments like catheter-directed thrombolysis(CDT)often result in variable success rates and complications.AIM To investigate the therapeutic efficacy of percutaneous mechanical thrombus removal in acute LEDVT.METHODS A retrospective analysis was performed to examine 58 hospitalised patients with acute LEDVT between August 2019 and August 2022.The patients were categorised into the percutaneous mechanical thrombectomy(PMT)group(n=24)and CDT group(n=32).The follow-up,safety and treatment outcomes were compared between the two groups.The main observational indexes were venous patency score,thrombus removal effect,complications,hospitalisation duration and PTS.RESULTS The venous patency score was 9.04±1.40 in the PMT group and 8.81±1.60 in the CDT group,and the thrombus clearance rate was 100%in both groups.The complication rate was 8.33%in the PMT group and 34.84%in the CDT group,and the difference was statistically significant(P<0.05).The average hospitalisation duration was 6.54±2.48 days in the PMT group and 8.14±3.56 days in the CDT group.The incidence of PTS was lower in the PMT group than in the CDT group;however,the difference was not statistically significant(P<0.05).CONCLUSION Compared with CDT,treatment of LEDVT via PMT was associated with a better thrombus clearance rate,clinical therapeutic effect and PTS prevention function,but the difference was not statistically significant.Moreover,PMT was associated with a reduced urokinase dosage,shortened hospitalisation duration and reduced incidence of complications,such as infections and small haemorrhages.These results indicate that PMT has substantial beneficial effects in the treatment of LEDVT.

Two-point compression ultrasonography: Enough to rule out lower extremity deep venous thrombosis?

BACKGROUND: Deep venous thrombosis(DVT) is a major cause of morbidity and is a common presenting complaint to the emergency department(ED). Point-of-care two-point compression ultrasonography has evolved as a quick and effective way of diagnosing DVT. The purpose of this study is to validate the prevalence and distribution of venous thrombi isolated to proximal lower extremity veins, other than common femoral and popliteal veins in patients with DVT.METHODS: This is a single-center retrospective study that looked at patients presenting to the ED of a tertiary care hospital between January 2014 and August 2018. The clinical presentation and laboratory and imaging results were obtained using the hospital's electronic medical record.RESULTS: A total of 2,507 patients underwent a lower extremity duplex ultrasound during the study period. Among them, 379(15%) were included in the study. The percentages of isolated thrombi to the femoral vein and deep femoral vein were 7.92% and 0.53%, respectively. When the patients were stratified into the two groups of isolated DVT and two-point compression DVT, there were no statistically significant differences in the laboratory results between both groups. However, immobilized patients and patients with recent surgeries were more likely to have an isolated DVT.CONCLUSIONS: Thrombi isolated to proximal lower extremity veins other than the common femoral and popliteal veins make up 8.45% of DVTs. Given this significant number of missed DVTs, the authors recommend the addition of the femoral and deep femoral veins to the two-point compression exam.

Analysis thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis in the lower extremities

Objective: To explore the effect of thrombolysis with anticoagulation treatment for early stage of deep vein thrombosis of lower extremity. Methods: The clinical data of 106 patients at the early stage of deep vein thrombosis (DVT) in the lower extremities treated by thrombolysis with anticoagulation and dispersion drugs were analyzed retrospectively. Results: The thrombolytic effect was significant. After treatment, the deep veins were recanalized without regurgitation in 75.3% of the patients. The total effective rate was 100%. Only three patients had hemorrhagic complication, but none of the patients died. Conclusion: Thrombolysis with anticoagulation treatment is an effective and safe method for DVT at the early stage.

Clinical Application of Percutaneous Transluminal Angioplasty and Stent Implantation in Acute Lower Extremity Deep Venous Thrombosis

Purpose: To analyze the application of percutaneous transluminal angioplasty and stenting in acute deep venous thrombosis of lower extremities. Methods: 70 patients were divided into two groups according to the presence or absence of percutaneous transluminal angioplasty and stenting. Results: The mean circumferential diameter difference between the affected limbs and the healthy limbs and the knees at 15 cm was statistically significant. The cure rate and effective rate of the research group were higher than those of the control group (P<0.05). Conclusion: Percutaneous transluminal angioplasty and stenting are of high value in acute lower extremity deep venous thrombosis.

Discussion on Prevention and Treatment of Lower Extremity Deep Venous Thrombosis in Orthopedic Perioperative Period from Spleen and Stomach Meridians

Deep venous thrombosis of lower extremity is one of the common complications in orthopedic perioperative period.It is caused by many factors,such as peripheral vein dilation,slow blood flow;long-term immobilization,bed rest and so on.On the one hand,it affects the early postoperative functional exercise and functional recovery,on the other hand,it increases the length of hospital stay and economic burden,increases the pain of patients and even endangers their lives.Effective treatment of traditional Chinese medicine combined with western medicine can play a better role in the prevention and treatment of lower extremity deep venous thrombosis.This study expounds the concept of spleen and stomach meridians in the prevention and treatment of lower extremity deep venous thrombosis,and puts forward some opinions on the dialectical treatment and daily conditioning of lower extremity deep venous thrombosis,hoping to provide ideas for the clinical prevention and treatment of lower extremity deep venous thrombosis in traditional Chinese medicine.

Deep Venous Thrombosis: Commonly Affected Veins in the Lower Limbs

Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow.

Comparison of four clinical scores for the predicting lower limb deep venous thrombosis in Chinese patients

Objective：To evaluate Wells, Kahn, St.Andr 6 and Constans scores for the prediction of deep venous thrombosis in Chinese patients. Methods：One hundred and seventy-two patients, prospectively, blinded referred for evaluation with four clinical-score systems for suspected deep venous thrombosis, were examined by ultrasonography. Sensitivity, specificity, positive predictive value, negative predictive value and receiver operation curves were calculated for four clinical scores. The difference between areas of the ROC curve for each of the scores was compared with others and reference line. Results：Forty-six of 172 patients had deep venous thrombosis proven by sonography. The sensitivity, specificity, positive predictive value and negative predictive value for Wells score was 91.3%, 57.1%, 43.8% and 94.7%, respectively, for Kahn score; 65.2%, 71.4%, 45.5% and 84.9%, respectively, for St.Andr 6 score; 63%, 38.9%, 27.4% and 74.2% respectively, for Constans score; 95.7%, 34.9%, 34.9% and 95.7% respectively. Area under ROV curve of Constans score was 0.814, which was similar to that of Wells score, then followed by Kahn score and that of St.Andr 6 score was no difference with the reference line. Conclusion：Based on the results of our study, the sensitivity, negative prediction value and area under ROC curve are larger for Constans score and Wells score in Chinese hospitalized patients than that of Kahn score or St.Andr 6 score. Considering the aim of the clinical assessment, Constans score and Wells score are more efficient for Chinese hospitalized patients.

椎管内麻醉与全身麻醉下手术的下肢骨折老年患者LDVT发生率比较

目的:比较椎管内麻醉与全身麻醉下手术对下肢骨折老年患者下肢深静脉血栓(LDVT)发生率的影响。方法:选取2020年1月至2022年1月在永城市人民医院接受手术治疗的90例下肢骨折老年患者,依据随机数字表将全部患者均分为对照组(全身麻醉)与观察组(椎管内麻醉),各45例。比较两组患者手术情况、术后恢复情况、麻醉情况、术中生命体征、术后48 h运动功能状态,统计术后LDVT与麻醉并发症发生率。结果:观察组患者手术时间、术中出血量、术后床旁活动时间及住院时间均少于对照组,差异具有统计学意义(P<0.05);观察组患者麻醉生效时间、术后睁眼时间、语言陈述恢复时间、术中麻醉药物用量均少于对照组,差异具有统计学意义(P<0.05);观察组患者麻醉后10 min(T1)、术毕即刻(T2)时心率、平均动脉压均低于对照组,差异具有统计学意义(P<0.05);观察组患者术后48 h的运动功能分级优于对照组,差异具有统计学意义(Z=2.183,P<0.05);观察组患者术后LDVT发生率与麻醉不良反应总发生率均低于对照组,差异具有统计学意义(P<0.05)。结论:椎管内麻醉与全身麻醉相比,能够有效降低下肢骨折老年患者术后LDVT发生风险。

血浆D-D、凝血因子、PC变化与乳腺癌根治术后发生DVT的多因素研究

目的探讨血浆D-二聚体(D-D)、凝血因子、血浆蛋白C(PC)与乳腺癌根治术后发生下肢深静脉血栓(DVT)的关系。方法选取接受乳腺癌根治术治疗且术后发生DVT的患者45例作为病例组,同期接受乳腺癌根治术未发生DVT的患者90例作为对照组;统计并分析两组的年龄、体质量指数(BMI)、乳腺癌病理学类型、肿瘤淋巴结转移分期(TNM)、辅助化疗、合并疾病情况、红细胞(RBC)、纤维蛋白原(FIB)、凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)、D-D、凝血因子Ⅷ(FⅧ)、血浆PC的水平,并采用向前Logistic回归分析法分析D-D、FⅧ、血浆PC与乳腺癌根治术后发生DVT的关系。结果两组年龄、体质量指数(BMI)、患侧分布、病理学类型、TNM分期、高血压、糖尿病、RBC、TT水平比较,差异无统计学意义(P>0.05),病例组的辅助性化疗患者占比、FIB水平均高于对照组,PT、APTT水平均低于对照组(P<0.05);病例组D-D、FⅧ水平高于对照组(P<0.05);病例组血浆PC水平低于对照组(P<0.05);Logistic回归模型结果显示FIB增高、D-D升高、FⅧ水平升高及APTT水平降低是乳腺癌根治术术后发生DVT的独立危险因素(OR=1.602,2.042,2.134,1.430,P<0.05)。结论引起乳腺癌术后发生DVT的因素众多,D-D、FⅧ水平升高会显著的增高乳腺癌根治术后发生DVT的风险。

CDT联合支架置入与系统溶栓治疗IVCS合并下肢DVT的效果及安全性对比

目的:探究并对比导管接触性溶栓(CDT)联合支架置入与系统溶栓治疗髂静脉受压综合征(IVCS)合并下肢深静脉血栓(DVT)的效果及安全性。方法:选取新余市人民医院2020年6月—2022年6月收治的70例IVCS合并下肢DVT患者作为研究对象,采用随机数字表法分为非手术组和手术组,各35例。非手术组患者给予系统溶栓治疗,手术组患者给予CDT联合支架置入治疗。观察并比较两组患者凝血指标[D-二聚体(D-D)、组织型纤溶酶原激活物(t-PA)、凝血酶原时间(PT)];静脉阻塞情况(阻塞评分、溶栓率、静脉通畅率);水肿情况(患肢围径差、消肿率);治疗期间住院情况(住院天数、住院费用);预后效果[继发性下肢深静脉瓣膜功能不全、下肢深静脉血栓后遗症(PTS)]。结果:治疗5 d后,手术组患者D-D水平低于非手术组,t-PA水平高于非手术组,PT长于非手术组(P<0.05)。治疗3个月后,手术组患者阻塞评分低于非手术组(P<0.05);手术组患者溶栓率、静脉通畅率均高于非手术组(P<0.05)。治疗3个月后,手术组患者膝上、膝下腿围径差均小于非手术组(P<0.05);手术组患者膝上、膝下消肿率均高于非手术组(P<0.05)。手术组患者住院天数少于非手术组(P<0.05)。手术组患者继发性下肢深静脉瓣膜功能不全发生率及PTS发生率均低于非手术组(P<0.05)。结论:CDT联合支架置入治疗用于IVCS合并下肢DVT患者可改善其临床症状,治疗效果较常规系统溶栓治疗更佳,且治疗后恢复更快,预后更为理想。

MAKO机器人辅助全髋关节置换术患者预防DVT的护理策略构建及实施效果探讨

目的:探讨MAKO机器人辅助全髋关节置换术患者预防下肢深静脉血栓(DVT)的护理策略构建及实施效果。方法:选取2022年1月—2023年8月首都医科大学附属北京积水潭医院收治的120例行MAKO机器人辅助全髋关节置换术的患者,随机分为对照组(n=60,常规护理)和观察组(n=60,构建预防DVT的护理干预策略),并比较两组患者DVT发生情况及肢体功能康复情况。结果:观察组在术后1周、2周的DVT发生率均低于对照组,差异有统计学意义(P<0.05)。观察组在术后第1 d、2 d、3 d、5 d、7 d的患肢周径差值及患肢疼痛数字等级评定量表(NRS)评分均低于对照组,差异有统计学意义(P<0.05);观察组在术后第1 d、3 d的D-二聚体(D-D)水平、纤维蛋白原(Fbg)水平、血浆黏度、红细胞聚集指数均低于对照组,差异有统计学意义(P<0.05)。观察组在出院时、出院1个月的Harris评分高于对照组,且观察组在出院时、出院3个月的步长、步速均高于对照组,差异有统计学意义(P<0.05)。结论:构建MAKO机器人辅助全髋关节置换术患者的围手术期护理策略,可减少术后DVT的发生,减轻患肢肿胀程度,促进患者关节功能恢复,值得临床应用。

急性和亚急性下肢DVT的超声鉴别诊断

目的 探讨超声检查鉴别急性和亚急性下肢深静脉血栓 (DVT)的可行性。方法 经超声诊断的 43例 46条下肢DVT患者 ,根据其诱因和症状出现的时间分为急性组和亚急性组 ,比较两组血栓形成部位、回声特点及病变静脉管径。结果 两组血栓的形成部位、回声特点有显著差别 (P <0 .0 5 ) ,而管径无明显差别 (P >0 .0 5 )。以低回声表现的局段性、周围型和中央型血栓诊断急性下肢DVT的特异性分别为 10 0 %、84.6%和 75 %。而以中回声表现的血栓和混合型血栓诊断亚急性下肢DVT的特异性分别为 10 0 %和 86.9%。结论 对于诱因及症状不明确的下肢DVT患者 ,根据超声检查多数可区别急性和亚急性DVT ,但少数仍不能明确区分。

滤器置入联合手术取栓治疗产后下肢DVT的临床分析

目的总结产后急性期单侧下肢深静脉血栓形成(DVT)腔静脉滤器联合手术取栓治疗的疗效及应用。方法回顾性分析59例产后单侧下肢急性期DVT行腔静脉滤器联合手术取栓治疗的患者临床资料。结果 56例成功行腔静脉滤器置入及手术切开取栓,3例因髂静脉近端血栓闭塞严重无法开通,股静脉切口远端成功行手术取栓,术后拔除腔静脉滤器。本组有效率为100%,治愈率为88.1%,无死亡及新发肺动脉栓塞病例。随访3～36个月,1例髂静脉狭窄病例于球囊扩张3个月后复发,再次手术置入髂静脉支架后患肢肿胀明显减轻。结论腔静脉滤器置入联合手术取栓治疗急性期产后单侧下肢DVT安全可行、疗效确切。

基于D-D、MMP-1、IR水平分析急性中毒患者血液净化联合达比加群酯的效果及下肢DVT危险因素

目的探究血液净化联合达比加群酯对急性中毒患者下肢深静脉血栓(DVT)的防治效果及对D-二聚体(D-D)、血清基质金属蛋白酶-1(MMP-1)、胰岛素抵抗(IR)水平的影响。方法选取本院急诊科在2020年2月至2021年8月期间诊治的160例急性中毒患者血清展开研究。160例患者按照数字表法随机分为两组,研究组、常规组均为80例患者。常规组使用血液净化治疗方案,研究组应用血液净化联合达比加群酯治疗方案,检测并对比两组患者的D-D、MMP-1、IR水平差异,记录对比两组患者的下肢DVT发生率并进一步分析影响因素。结果(1)K-S检验显示所有计量资料均呈正态分布(P>0.05),两组的D-D均呈降低趋势变化且研究组变化幅度更大(P<0.05)。(2)两组的MMP-1水平均呈降低趋势变化且研究组的变化幅度更大(P<0.05)。(3)两组的IR水平均呈降低趋势变化且研究组的变化幅度更大(P<0.05)。(4)相比于常规组,研究组的下肢DVT发生率明显降低(P<0.05)。年龄≥60岁、BMI≥24kg/m 2、中度以上中毒者、D-D≥0.5mg/L的下肢DVT发生率明显升高,是下肢DVT发生的危险因素(P<0.05)。结论血液净化治疗联合达比加群酯治疗可以改善急性中毒患者的D-D、MMP-1、IR水平,同时该方案具有一定的安全性。针对存在下肢DVT风险的急性中毒患者进行重点看护。

风险预警机制护理对腹腔镜子宫肌瘤切除术患者血清D-D、FDP、TAT及DVT发生率的影响研究

目的:研究风险预警机制建立的干预方法及其在腹腔镜下子宫切除术(LTH)患者护理中的应用价值。方法:将于某院行LTH治疗的100例患者随机分为C组和C+F组各50例,C组采用常规护理,C+F组在C组的基础上采用下肢深静脉血栓(DVT)风险预警机制干预。于两组患者护理前后,分别检查血清血栓因子(D-D、FDP、TAT),并统计术后DVT的发生率及生活质量。结果:干预后,C+F组患者血清D-D、FDP、TAT均低于C组(P<0.05);C+F组患者下肢肿胀、DVT的发生率依次为10%、2%,均低于C组的26%、10%(P<0.05);C+F组生活质量显著高于C组(P<0.05)。结论:于LTH患者护理中通过建立DVT风险预警机制能有效降低血栓因子水平,预防DVT发生并提高患者生活质量,值得推广和应用。

补阳还五汤加减防治股骨粗隆间骨折术后早期下肢DVT形成

目的:观察补阳还五汤加减方对股骨粗隆间骨折术后早期下肢深静脉血栓(DVT)形成的防治效果及作用机制。方法:104例患者随机分为对照组和治疗组各52例。两组均采用低分子量肝素钙注射液预防DVT,术前1 h预防性用药1次,术后每天腹壁下注射4100 U,连续用药14 d。治疗组在此基础上于术后第1天开始加服补阳还五汤加减方,水煎服,日1剂,早晚分服,连续14 d。两组分别观察DVT发生率,观察记录患肢肿胀程度、股静脉血流速度和术后引流量,检测血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白介素-1(IL-1)、白介素-6(IL-6)及各项凝血指标水平。结果:治疗组DVT总发生率5.77%,低于对照组的19.23%(P<0.01);术后第7、14天,治疗组髌上和髌下肿胀程度均轻于对照组(P<0.01);术后第14天治疗组血清CRP、TNF-α、IL-1和IL-6水平均低于对照组(P<0.01);两组术后第14天血清D-二聚体(D-dimer)均下降,治疗组低于对照组(P<0.01)。结论:股骨粗隆间骨折术后使用补阳还五汤加减方可明显改善患者症状和体征,降低血清CRP、TNF-α、IL-1、IL-6和D-dimer水平,减轻炎症反应,预防DVT发生。

探讨分级监控管理联合精细化护理预防重症颅脑损伤术后下肢深静脉血栓形成(DVT)的价值

目的探讨对重症颅脑损伤术后患者行分级监控管理+精细化护理后预防术后下肢深静脉血栓(DVT)形成的效果。方法以2020年6月-2021年8月在本院接受手术治疗的重症颅脑损伤患者64例为研究对象,以随机数字表法进行分组,每组患者32例。观察组患者接受分级监控管理+精细化护理,对照组接受常规护理。对比两组护理前后股、腘静脉血流速度、下肢深静脉血栓形成情况以及生活质量改善情况。结果腘静脉、股静脉血流速度指标以及物质生活、社会功能、心理健康、躯体健康评分指标对比,护理后两组均高于干预前(P<0.05),而组间对比,为观察组更高(P<0.05);组间术后发生下肢深静脉血栓对比,为观察组更低(P<0.05)。结论对重症颅脑损伤术后患者行分级监控管理+精细化护理干预,术后股、腘静脉血流速度得以提高,明显降低了DVT的形成率,保障了患者术后生活质量。

髋关节置换术围术期FM动态检测在下肢DVT早期诊断中的意义

目的探讨髋关节置换术围术期纤维蛋白单体(FM)动态检测在下肢深静脉血栓(DVT)早期诊断中的意义。方法选取2017年3月至2018年6月在该院行髋关节置换术的患者120例,于入院第2天以及术后1、3、7d行下肢静脉彩超检查,根据多普勒彩色超声检查结果分为DVT组与非DVT组,统计入院第2天以及术后1、3、7dFM、D-二聚体(D-D)、纤维蛋白原(FIB)及纤维蛋白降解产物(FDP)水平,比较术后FM、D-D、FIB、FDP不同时点单独及联合诊断的灵敏度与特异度。结果 FM、D-D、FDP均在术后1d明显增高,术后3d短暂下降,术后7d又出现增高,均明显高于术前,且DVT组高于非DVT组(P<0.05),FIB术后处于较平稳状态,且DVT组高于非DVT组(P<0.05);FM在术后1、3、7d单独诊断DVT的灵敏度与特异度均高于DD、FIB、FDP;FM+D-D+FIB+FDP联合检测在术后1、3、7d的特异度均明显高于FM、D-D、FIB、FDP单独检测,且在术后3d检测时的灵敏度与特异度分别为93.55%、94.38%。结论与D-D、FIB、FDP相比,FM单独检测DVT具有更高的灵敏度与特异度,FM、D-D、FIB、FDP联合检测可提高术后DVT诊断的特异度,且在术后3d其灵敏度与特异度最为理想。