The effect of zinc(Zn) deficiency and excessive bicarbonate on the allocation and exudation of organic acids in plant organs(root, stem, and leaf) and root exudates of two Moraceae plants(Broussonetia papyrifera and M...The effect of zinc(Zn) deficiency and excessive bicarbonate on the allocation and exudation of organic acids in plant organs(root, stem, and leaf) and root exudates of two Moraceae plants(Broussonetia papyrifera and Morus alba) were investigated. Two Moraceae plants were hydroponically grown and cultured in nutrient solution in four different treatments with 0.02 mM Zn or no Zn,combined with no or 10 mM bicarbonate. The variations of organic acids in different plant organs were similar to those of root exudates in the four treatments except B. papyrifera, which was in a treatment that was a combination of 0.02 mM Zn and no bicarbonate. The response characteristics in the production, translocation, and allocation of organic acids in the plant organs and root exudates varied with species and treatments. Organic acids in plant organs and root exudates increased under Zn-deficient conditions,excessive bicarbonate, or both. An increase of organic acids in the leaves resulted in an increase of root-exuded organic acids. B. papyrifera translocated more oxalate and citrate from the roots to the rhizosphere than M. alba under the dual influence of 10 mM bicarbonate and Zn deficiency. Organic acids of leaves may be derived from dark respiration and photorespiration. By comparison, organic acids in stems, roots, and root exudates may be derived from dark respiration and organic acid translocation from the leaves. These results provide evidence for the selective adaptation of plants to environments with low Zn levels or high bicarbonate levels such as a karst ecosystem.展开更多
[目的]基于数据挖掘探讨中药治疗高血压肾损害的用药规律。[方法]收集中国知网(China National Knowledge Infrastructure,CNKI)建库至2022年3月运用中药治疗高血压肾损害的文献,按照纳入排除标准筛选处方,构建方药数据库,利用数据挖掘...[目的]基于数据挖掘探讨中药治疗高血压肾损害的用药规律。[方法]收集中国知网(China National Knowledge Infrastructure,CNKI)建库至2022年3月运用中药治疗高血压肾损害的文献,按照纳入排除标准筛选处方,构建方药数据库,利用数据挖掘技术对药物频次、类别、性味归经、聚类及关联规则进行分析。[结果]最终纳入文献85篇,方剂90首,中药144味,累及用药频次966次。使用频次前5位的中药依次是牛膝、黄芪、丹参、茯苓、杜仲。累计用药16类,排名前5的类别是补虚药、活血化瘀药、清热药、平肝息风药、利水渗湿药。中药性味及归经分析显示,常用药物以甘、平为主,归经主要为肝经、肾经、脾经。系统聚类可分为6类,涉及六味地黄丸、天麻钩藤饮等。关联规则分析共提取药对关联规则9条,药组关联规则10条,核心配伍的功效为补益肝肾、平肝潜阳。[结论]现代医家认为,高血压肾损害病性为本虚标实,治疗该病当以补虚为核心,随证治以清热利湿、活血化瘀、利水渗湿之法。展开更多
从病因病机、治则、遣方用药、疗效评价等角度对近20年中医药治疗胃癌前病变(precancerous lesion of gastric cancer,PLGC)的文献进行综述。中医学认为PLGC的病位在胃,与脾关系密切,基本病机为本虚标实、虚实夹杂,本虚为脾胃虚,标实有...从病因病机、治则、遣方用药、疗效评价等角度对近20年中医药治疗胃癌前病变(precancerous lesion of gastric cancer,PLGC)的文献进行综述。中医学认为PLGC的病位在胃,与脾关系密切,基本病机为本虚标实、虚实夹杂,本虚为脾胃虚,标实有血瘀、气滞、毒邪、痰凝、湿阻等。针对PLGC不同病机,多个学术团队研发出了多个经验方,在PLGC治疗方面有了长足发展,但也面临着疗效评价规范性等问题,有待整合国内外优势研究力量,集中开展大样本、高质量临床研究,做出中西医广泛认可的研究成果。展开更多
基金funded by the National Key Basic Research Program of China under Grant No. 2013CB956701the National Natural Science Foundation of China under Grant No. 31070365Funded by talents introduction of Anqing Normal University (No. 14000100032)
文摘The effect of zinc(Zn) deficiency and excessive bicarbonate on the allocation and exudation of organic acids in plant organs(root, stem, and leaf) and root exudates of two Moraceae plants(Broussonetia papyrifera and Morus alba) were investigated. Two Moraceae plants were hydroponically grown and cultured in nutrient solution in four different treatments with 0.02 mM Zn or no Zn,combined with no or 10 mM bicarbonate. The variations of organic acids in different plant organs were similar to those of root exudates in the four treatments except B. papyrifera, which was in a treatment that was a combination of 0.02 mM Zn and no bicarbonate. The response characteristics in the production, translocation, and allocation of organic acids in the plant organs and root exudates varied with species and treatments. Organic acids in plant organs and root exudates increased under Zn-deficient conditions,excessive bicarbonate, or both. An increase of organic acids in the leaves resulted in an increase of root-exuded organic acids. B. papyrifera translocated more oxalate and citrate from the roots to the rhizosphere than M. alba under the dual influence of 10 mM bicarbonate and Zn deficiency. Organic acids of leaves may be derived from dark respiration and photorespiration. By comparison, organic acids in stems, roots, and root exudates may be derived from dark respiration and organic acid translocation from the leaves. These results provide evidence for the selective adaptation of plants to environments with low Zn levels or high bicarbonate levels such as a karst ecosystem.
文摘[目的]基于数据挖掘探讨中药治疗高血压肾损害的用药规律。[方法]收集中国知网(China National Knowledge Infrastructure,CNKI)建库至2022年3月运用中药治疗高血压肾损害的文献,按照纳入排除标准筛选处方,构建方药数据库,利用数据挖掘技术对药物频次、类别、性味归经、聚类及关联规则进行分析。[结果]最终纳入文献85篇,方剂90首,中药144味,累及用药频次966次。使用频次前5位的中药依次是牛膝、黄芪、丹参、茯苓、杜仲。累计用药16类,排名前5的类别是补虚药、活血化瘀药、清热药、平肝息风药、利水渗湿药。中药性味及归经分析显示,常用药物以甘、平为主,归经主要为肝经、肾经、脾经。系统聚类可分为6类,涉及六味地黄丸、天麻钩藤饮等。关联规则分析共提取药对关联规则9条,药组关联规则10条,核心配伍的功效为补益肝肾、平肝潜阳。[结论]现代医家认为,高血压肾损害病性为本虚标实,治疗该病当以补虚为核心,随证治以清热利湿、活血化瘀、利水渗湿之法。
文摘从病因病机、治则、遣方用药、疗效评价等角度对近20年中医药治疗胃癌前病变(precancerous lesion of gastric cancer,PLGC)的文献进行综述。中医学认为PLGC的病位在胃,与脾关系密切,基本病机为本虚标实、虚实夹杂,本虚为脾胃虚,标实有血瘀、气滞、毒邪、痰凝、湿阻等。针对PLGC不同病机,多个学术团队研发出了多个经验方,在PLGC治疗方面有了长足发展,但也面临着疗效评价规范性等问题,有待整合国内外优势研究力量,集中开展大样本、高质量临床研究,做出中西医广泛认可的研究成果。
