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The potential value of CDV3 in the prognosis evaluation in Hepatocellular carcinoma
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作者 Heng Xiao Baoyong Zhou +5 位作者 Ning Jiang Yunshi Cai Xiongwei Liu Zhengrong Shi Ming Li Chengyou Du 《Genes & Diseases》 SCIE 2018年第2期167-171,共5页
CDV3 is correlated with tumorigenesis and may affect some biological process in cancer.In this study,we explore the role of CDV3 in HCC.According to the TCGA data base,CDV3 is over-expressed in HCC tissues.Up-regulati... CDV3 is correlated with tumorigenesis and may affect some biological process in cancer.In this study,we explore the role of CDV3 in HCC.According to the TCGA data base,CDV3 is over-expressed in HCC tissues.Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients.In HCC samples from our hospital,CDV3 is also enriched in cancer tissues and CDV3 expression associated with HCC pathological T stage.What is more,higher CDV3 expression could forecast poor survival rate in HCC patients.In conclusion,CDV3 is a biomarker of HCC and could be a potential therapeutic target. 展开更多
关键词 Carnitine deficiencyassociated gene expressed in ventricle 3(CDV3) Hepatocellular carcinoma(HCC) The cancer genome Atlas(TCGA) Prognostic value Therapeutic biomarker
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