CDV3 is correlated with tumorigenesis and may affect some biological process in cancer.In this study,we explore the role of CDV3 in HCC.According to the TCGA data base,CDV3 is over-expressed in HCC tissues.Up-regulati...CDV3 is correlated with tumorigenesis and may affect some biological process in cancer.In this study,we explore the role of CDV3 in HCC.According to the TCGA data base,CDV3 is over-expressed in HCC tissues.Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients.In HCC samples from our hospital,CDV3 is also enriched in cancer tissues and CDV3 expression associated with HCC pathological T stage.What is more,higher CDV3 expression could forecast poor survival rate in HCC patients.In conclusion,CDV3 is a biomarker of HCC and could be a potential therapeutic target.展开更多
基金This study was funded by The National Natural Science Foundation of China(Grant No.81702408)the Science Foundation for Fostering Talents of The First Affiliated Hospital of Chongqing Medical University(Grant No.PYJJ2017-08)The Medical research program from Board of Health in Chongqing(Grant No.2013-2-009).
文摘CDV3 is correlated with tumorigenesis and may affect some biological process in cancer.In this study,we explore the role of CDV3 in HCC.According to the TCGA data base,CDV3 is over-expressed in HCC tissues.Up-regulation of CDV3 is correlated with lower over-all survival rate in HCC patients.In HCC samples from our hospital,CDV3 is also enriched in cancer tissues and CDV3 expression associated with HCC pathological T stage.What is more,higher CDV3 expression could forecast poor survival rate in HCC patients.In conclusion,CDV3 is a biomarker of HCC and could be a potential therapeutic target.