While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell canc...While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell cancer is rising.Literature concerning PCC-GC is scarce and unclear,mostly due to a large variety of historically used definitions and classifications.Compared to other histological subtypes of GC,PCC-GC is nevertheless characterized by a distinct set of epidemiological,histological and clinical features which require a specific diagnostic and therapeutic approach.The aim of this review was to provide an update on the definition,classification and therapeutic strategies of PCC-GC.We focus on the updated histological definition of PCC-GC,along with its implications on future treatment strategies and study design.Also,specific considerations in the diagnostic management are discussed.Finally,the impact of some recent developments in the therapeutic management of GC in general such as the recently validated taxane-based regimens(5-Fluorouracil,leucovorin,oxaliplatin and docetaxel),the use of hyperthermic intraperitoneal chemotherapy as well as pressurized intraperitoneal aerosol chemotherapy and targeted therapy have been reviewed in depth for their relative importance for PCC-GC in particular.展开更多
We examine the constraints to conservation and to successful forestlands’ monitoring/assessments in central Togo through GIS spatial analyses and through a critical overview of the current forestry administration’s ...We examine the constraints to conservation and to successful forestlands’ monitoring/assessments in central Togo through GIS spatial analyses and through a critical overview of the current forestry administration’s model. The major findings are that the land classification based on few inventory parameters cannot substitute for “what forest is”, rather these inventory parameters constitute a mean to sound forest management and conservation when relevantly decided. Also as these parameters measured from satellite imagery are supplemented by continuous fine management data they may consistently contribute to the classification of the vegetation cover. This helps to suggest that solution to forest degradation/deforestation, and monitoring/ assessment requires data refinement through local forest management. Else, the actual forestry administration is local communities and indigenous people’s needs biased because it has been negligent of the cultural forestry practices, the major constraints to conservation and the monitoring/assessment of forest lands. As a common pool-resource, the questions relative to forest cannot be addressed at a single environmental concerns level. Interests are multiple and various along the spectrum from the global environment level to the local environmental level that should be accounted for. Thus we recommend a reconsideration of the forestry administration model. What is required are simple policies processes to define forest management plans that promote simultaneously sustainable forest management while accounting for any stakeholder concern, importantly the cultural forestry that addresses specific local communities and indigenous people’s forest related interests.展开更多
Glacial lakes are not only the important refresh water resources in alpine region, but also act as a trigger of many glacial hazards such as glacial lake outburst flood （GLOF） and debris flow. Therefore, glacial lak...Glacial lakes are not only the important refresh water resources in alpine region, but also act as a trigger of many glacial hazards such as glacial lake outburst flood （GLOF） and debris flow. Therefore, glacial lakes play an important role on the cryosphere, climate change and alpine hazards. In this paper, the issues of glacial lake were systematically discussed, then from the view of glacial lake inventory and glacial lake hazards study, the glacial lake was defined as natural water mainly supplied by modern glacial meltwater or formed in glacier moraine＇s depression. Furthermore, a complete classification system of glacial lake was proposed based on its formation mechanism, topographic feature and geographical position. Glacial lakes were classified as 6 classes and 8 subclasses, i.e., glacial erosion lake （including cirque lake, gla- cial valley lake and other glacial erosion lake）, moraine-dammed lake （including end mo- raine-dammed lake, lateral moraine-dammed lake and moraine thaw lake）, ice-blocked lake （including advancing glacier-blocked lake and other glacier-blocked lake）, supraglacial lake, subglacial lake and other glacial lake. Meanwhile, some corresponding features exhibiting on remote sensing image and quantitative indices for identifying different glacial lake types were proposed in order to build a universal and operational classification system of glacial lake.展开更多
Definition and Classification of Acute Kidney Injury Before the RIFLE classification system of acute renal failure（ARF） was proposed in the Second Conference of Acute Dialysis Quality Initiative （ADQI,an internatio...Definition and Classification of Acute Kidney Injury Before the RIFLE classification system of acute renal failure（ARF） was proposed in the Second Conference of Acute Dialysis Quality Initiative （ADQI,an international volunteer organization mainly composed of intensivists and nephrologists in developed countries） in 2002, there were more than 35 diagnostic criteria of ARF in different literatures, which led to confusion in clinical practice and epidemiological investigation.展开更多
文摘While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell cancer is rising.Literature concerning PCC-GC is scarce and unclear,mostly due to a large variety of historically used definitions and classifications.Compared to other histological subtypes of GC,PCC-GC is nevertheless characterized by a distinct set of epidemiological,histological and clinical features which require a specific diagnostic and therapeutic approach.The aim of this review was to provide an update on the definition,classification and therapeutic strategies of PCC-GC.We focus on the updated histological definition of PCC-GC,along with its implications on future treatment strategies and study design.Also,specific considerations in the diagnostic management are discussed.Finally,the impact of some recent developments in the therapeutic management of GC in general such as the recently validated taxane-based regimens(5-Fluorouracil,leucovorin,oxaliplatin and docetaxel),the use of hyperthermic intraperitoneal chemotherapy as well as pressurized intraperitoneal aerosol chemotherapy and targeted therapy have been reviewed in depth for their relative importance for PCC-GC in particular.
文摘We examine the constraints to conservation and to successful forestlands’ monitoring/assessments in central Togo through GIS spatial analyses and through a critical overview of the current forestry administration’s model. The major findings are that the land classification based on few inventory parameters cannot substitute for “what forest is”, rather these inventory parameters constitute a mean to sound forest management and conservation when relevantly decided. Also as these parameters measured from satellite imagery are supplemented by continuous fine management data they may consistently contribute to the classification of the vegetation cover. This helps to suggest that solution to forest degradation/deforestation, and monitoring/ assessment requires data refinement through local forest management. Else, the actual forestry administration is local communities and indigenous people’s needs biased because it has been negligent of the cultural forestry practices, the major constraints to conservation and the monitoring/assessment of forest lands. As a common pool-resource, the questions relative to forest cannot be addressed at a single environmental concerns level. Interests are multiple and various along the spectrum from the global environment level to the local environmental level that should be accounted for. Thus we recommend a reconsideration of the forestry administration model. What is required are simple policies processes to define forest management plans that promote simultaneously sustainable forest management while accounting for any stakeholder concern, importantly the cultural forestry that addresses specific local communities and indigenous people’s forest related interests.
基金National Natural Science Foundation of China,No.41261016,No.41561016Opening Foundation Projection of State Key Laboratory of Cryosphere Sciences,CAS,No.SKLCS-OP-2016-10+1 种基金Youth Scholar Scientific Capability Promoting Project of Northwest Normal University,No.NWNU-LKQN-14-4Geological Survey Project of China Geological Survey,No.DD2016034206
文摘Glacial lakes are not only the important refresh water resources in alpine region, but also act as a trigger of many glacial hazards such as glacial lake outburst flood （GLOF） and debris flow. Therefore, glacial lakes play an important role on the cryosphere, climate change and alpine hazards. In this paper, the issues of glacial lake were systematically discussed, then from the view of glacial lake inventory and glacial lake hazards study, the glacial lake was defined as natural water mainly supplied by modern glacial meltwater or formed in glacier moraine＇s depression. Furthermore, a complete classification system of glacial lake was proposed based on its formation mechanism, topographic feature and geographical position. Glacial lakes were classified as 6 classes and 8 subclasses, i.e., glacial erosion lake （including cirque lake, gla- cial valley lake and other glacial erosion lake）, moraine-dammed lake （including end mo- raine-dammed lake, lateral moraine-dammed lake and moraine thaw lake）, ice-blocked lake （including advancing glacier-blocked lake and other glacier-blocked lake）, supraglacial lake, subglacial lake and other glacial lake. Meanwhile, some corresponding features exhibiting on remote sensing image and quantitative indices for identifying different glacial lake types were proposed in order to build a universal and operational classification system of glacial lake.
文摘Definition and Classification of Acute Kidney Injury Before the RIFLE classification system of acute renal failure（ARF） was proposed in the Second Conference of Acute Dialysis Quality Initiative （ADQI,an international volunteer organization mainly composed of intensivists and nephrologists in developed countries） in 2002, there were more than 35 diagnostic criteria of ARF in different literatures, which led to confusion in clinical practice and epidemiological investigation.
