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Acetylcholinesterase inhibitor modifications: a promising strategy to delay the progression of Alzheimer's disease 被引量:5
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作者 Soumee Bhattacharya Dirk Montag 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第1期43-45,共3页
Alzheimer's disease (AD), a fatal, progressive, neurodegener- ative disorder, is the most common cause of old-age demen- tia, accounting for 50-75% of dementia patients. Early stages of AD are marked by vocabulary ... Alzheimer's disease (AD), a fatal, progressive, neurodegener- ative disorder, is the most common cause of old-age demen- tia, accounting for 50-75% of dementia patients. Early stages of AD are marked by vocabulary shrinkage, spatial disori- entation, depression, apraxia, and deterioration of recent forms of declarative memory. In course of time, the patients require close supervision due to the loss of cognitive and functional abilities, and at the terminal stages of the disease, all forms of memory are severely impaired with the patients needing nursing home care (World Alzheimer Report, 2013). 展开更多
关键词 Acetylcholinesterase inhibitor modifications a promising strategy to delay the progression of Alzheimer’s disease ACH ORAL
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