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Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer
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作者 Jie Chang Ruirui Yang +11 位作者 Lifan Chen Zisheng Fan Jingyi Zhou Hao Guo Yinghui Zhang Yadan Liu Guizhen Zhou Keke Zhang Kaixian Chen Hualiang Jiang Mingyue Zheng Sulin Zhang 《Acta Pharmaceutica Sinica B》 SCIE CAS CSCD 2022年第5期2619-2622,共4页
To the Editor:ADP-ribosylation factor 1 (ARF1) plays a critical role in regulating vesicle formation and transport1. The dysregulation of ARF1 expression and/or activity is involved in many human cancers, such as brea... To the Editor:ADP-ribosylation factor 1 (ARF1) plays a critical role in regulating vesicle formation and transport1. The dysregulation of ARF1 expression and/or activity is involved in many human cancers, such as breast cancer2,3. Therefore, ARF1 is one of the promising therapeutic targets for cancer treatment. 展开更多
关键词 ADP-ribosylation factor 1 Breast cancer demethylzeylasteral Virtual screening
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