The preliminary results for one-pot synthesis of dendronized aromatic polyamides with chloromethyl groups in the periphery by approach were reported first time. The GPC analysis of the resulting dendronized polymers h...The preliminary results for one-pot synthesis of dendronized aromatic polyamides with chloromethyl groups in the periphery by approach were reported first time. The GPC analysis of the resulting dendronized polymers has shown typical weight average molecular weight （Mw） of 41554 and a polydispersity of 2.74.展开更多
Tri-block amphiphilic copolymers with hybrid architectures were synthesized by coupling linear （poly（ethylene） glycol）（PEG） and dendritic second-generation Fréchet-type poly（benzyl ether）（PBE） via the W...Tri-block amphiphilic copolymers with hybrid architectures were synthesized by coupling linear （poly（ethylene） glycol）（PEG） and dendritic second-generation Fréchet-type poly（benzyl ether）（PBE） via the Williamson reaction （Gisotv,et al. Angew Chem,Int Ed Engl,1992,31:1200～1202）.Our experimental study shows that the powerful two-dimensional （）1H- （）13C heteronuclear multiple-quantum correlation （HMQC） and two-dimensional （）1H- （）13C heteronuclear multiple-bond correlation （HMBC） NMR techniques rather than the classical one-dimensional （）1H and （）13C-NMR methods can provide clear evidence to verify the formation of the tri-block copolymers.In our measurements HMQC and HMBC NMR techniques directly detected the signal of ether bonds bridged in-between PBE dendrons and PEG blocks,therefore,the formation of the block copolymers are evidently confirmed in molecular level.This work also provides a general method to exactly confirm the formation of block copolymers.展开更多
The synthesis and characterization of a series of peptide dendronswith glycin（Gly） and glutamate（Glu） as building blocks were described.The dendrons were prepared with convergent method by protection,deprotection ...The synthesis and characterization of a series of peptide dendronswith glycin（Gly） and glutamate（Glu） as building blocks were described.The dendrons were prepared with convergent method by protection,deprotection and DCC coupling reactions.With the characterization of elemental analysis,（）1H-NMR,（）13C-NMR,FTIR,EI-MS and MAILD-TOF MS,the designed molecular structure was proved.It could be predicted that the obtained compounds will exhibit unique properties and potential applications in the fields of biology,medicine and so on.Further studies on the properties of these compounds are in progress.展开更多
文摘The preliminary results for one-pot synthesis of dendronized aromatic polyamides with chloromethyl groups in the periphery by approach were reported first time. The GPC analysis of the resulting dendronized polymers has shown typical weight average molecular weight （Mw） of 41554 and a polydispersity of 2.74.
文摘Tri-block amphiphilic copolymers with hybrid architectures were synthesized by coupling linear （poly（ethylene） glycol）（PEG） and dendritic second-generation Fréchet-type poly（benzyl ether）（PBE） via the Williamson reaction （Gisotv,et al. Angew Chem,Int Ed Engl,1992,31:1200～1202）.Our experimental study shows that the powerful two-dimensional （）1H- （）13C heteronuclear multiple-quantum correlation （HMQC） and two-dimensional （）1H- （）13C heteronuclear multiple-bond correlation （HMBC） NMR techniques rather than the classical one-dimensional （）1H and （）13C-NMR methods can provide clear evidence to verify the formation of the tri-block copolymers.In our measurements HMQC and HMBC NMR techniques directly detected the signal of ether bonds bridged in-between PBE dendrons and PEG blocks,therefore,the formation of the block copolymers are evidently confirmed in molecular level.This work also provides a general method to exactly confirm the formation of block copolymers.
文摘The synthesis and characterization of a series of peptide dendronswith glycin（Gly） and glutamate（Glu） as building blocks were described.The dendrons were prepared with convergent method by protection,deprotection and DCC coupling reactions.With the characterization of elemental analysis,（）1H-NMR,（）13C-NMR,FTIR,EI-MS and MAILD-TOF MS,the designed molecular structure was proved.It could be predicted that the obtained compounds will exhibit unique properties and potential applications in the fields of biology,medicine and so on.Further studies on the properties of these compounds are in progress.
